3d And 4d Printing In Biomedical Applications

Ein professioneller Leitfaden zu 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie. 3D and 4D Printing in Biomedical Applications führt fundiert in 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie ein. Dieses Fachbuch enthält Beiträge von internationalen Wissenschaftlern und Industrieexperten und bietet einen Überblick über das Thema, aktuelle Forschungsergebnisse und Innovationen zu Anwendungen in der Pharmazie und Biomedizin. Untersucht werden Prozessoptimierung, Innovationsprozesse, Engineering- und Plattformtechnologien. Darüber hinaus informiert das Werk über Entwicklungen in der Biomedizin, u. a. über Formgedächtnispolymere, Biofabrikation in 4D und Knochen aus dem Drucker. Eine Fülle von Themen werden behandelt und näher beleuchtet: Potenzial des 3D-Drucks für die Wirkstoffverabreichung, neue Fertigungsprozess, Bio-Scaffolding, neueste Trends und Herausforderungen für 3D- und 4D-Bioprinting in der Biofabrikation. Dieses wertvolle Referenzwerk - ist ein umfassender Leitfaden zu 3D- und 4D-Drucktechniken in der Biomedizin und Pharmazie. - informiert u. a. über die erste 3D-Druckplattform mit FDA-Zulassung für ein pharmazeutisches Erzeugnis. - enthält Reviews der derzeit verfügbaren pharmazeutischen Erzeugnisse, die per 3D-Druck hergestellt wurden. - präsentiert die jüngsten Fortschritte bei neuartigen Materialien für den 3D- und 4D-Druck und biomedizinische Anwendungen.

3D and 4D Printing of Polymer Nanocomposite Materials: Processing, Applications, and Challenges covers advanced 3D and 4D printing processes and the latest developments in novel polymer-based printing materials, thus enabling the reader to understand and benefit from the advantages of this groundbreaking technology. The book presents processes, materials selection, and printability issues, along with sections on the preparation of polymer composite materials for 3D and 4D printing. Across the book, advanced printing techniques are covered and discussed thoroughly, including fused deposition modeling (FDM), selective laser sintering (SLS), selective laser melting (SLM), electron beam melting (EBM), inkjet 3D printing (3DP), stereolithography (SLA), and 3D plotting. Finally, major applications areas are discussed, including electronic, aerospace, construction and biomedical applications, with detailed information on the design, fabrication and processing methods required in each case. Provides a thorough, clear understanding of polymer preparation techniques and 3D and 4D printing processes, with a view to specific applications Examines synthesis, formation methodology, the dispersion of fillers, characterization, properties, and performance of polymer nanocomposites Explores the possibilities of 4D printing, covering the usage of stimuli responsive hydrogels and shape memory polymers

4D-Printed Smart Materials and Structures: Mechanics, Modeling, and Advanced Engineering Applications provides a thorough introduction to the fundamentals of the mechanics, manufacturing, modeling and applications of 4D printed smart materials and structures. The book starts by covering the basic theories, definitions and fabrication details of 4D printing and various smart materials such as shape memory polymers, stimuli-responsive hydrogels, pneumatic soft actuators, dielectric elastomer soft robots, liquid crystal elastomers, shape memory alloys, and magnetic stimulus structures. The book then examines the mechanics of these materials and their various applications, covering topics such as variable stiffness, miniature-sized 4D printing, and more. The book also includes a chapter on machine learning in 4D printing and provides applications in mechanical, aerospace, civil and structural engineering, among others. Covers the mechanics, manufacturing processes and applications of 4D-printed smart materials and structures Discusses applications in civil, mechanical, aerospace, polymer and biomedical engineering Presents experimental, numerical and analytical studies in a simple and straightforward manner, providing tools that can be immediately implemented and adapted by readers to fit their work

Materials Development and Processing for Biomedical Applications focuses on various methods of manufacturing, surface modifications, and advancements in biomedical applications. This book examines in detail about five different aspects including, materials properties, development, processing, surface coatings, future perspectives and fabrication of advanced biomedical devices. Fundamental aspects are discussed to better understand the processing of various biomedical materials such as metals, ceramics, polymers, composites, etc. A wide range of surface treatments are covered in this book that will be helpful for the readers to understand the importance of surface treatments and their future perspectives. Additional Features Include: Examines various properties of biomedical materials at the beginning in several chapters which will enrich the fundamental knowledge of the readers. Discusses advancements in various fields of biomedical applications. Provides a glimpse of characterization techniques for the evaluation of material properties. Addresses biocompatibility, biocorrosion, and tribocorrosion. This book explores new and novel strategies for the development of materials and their biomedical applications. It will serve as a comprehensive resource for both students and scientists working in materials and biomedical sciences.

Food Processing and Preservation Technology: Advances, Methods, and Applications confronts the challenges of food preservation by providing new research and information on the use of novel processing and preservation technologies during production, processing, and transportation in the food industry for the improvement of shelf life and the safety of foods. The book is organized in two main parts. The first section focuses on novel and nonthermal processing of food and food products. It looks at dielectric heating and ohmic heating as well as three-dimensional printing of foods and ozonization of food products. Part two delves into process interventions for food processing and preservations, discussing the applications of diverse novel food processing. The authors discuss drying technologies, advances in food fermentation technologies, mechanization of traditional indigenous products for preservation of food and safety, and different properties and concepts of bakery products. Key features: Examines different properties and attributes of some bakery foods, etc. Elucidates on novel nonthermal processing techniques and their mechanisms of actions for minimal loss of food nutrients and for food safety Discusses a variety of modern technologies that aim to reduce the spoilage of food products This volume presents valuable research on food processing, quality control, and safety measures for food products by means of novel processing and preservation technologies during production, processing, and transportation in the food industry.

4D-Printed Smart Materials and Structures: Smart Materials in Additive Manufacturing, Volume Two provides a thorough introduction to the fundamentals of the mechanics, manufacturing, modeling and applications of 4D printed smart materials and structures. The book covers basic theories, definitions and fabrication details of 4D printing and various smart materials such as shape memory polymers, stimuli-responsive hydrogels, pneumatic soft actuators, dielectric elastomer soft robots, liquid crystal elastomers, shape memory alloys, and magnetic stimulus structures. In addition, it examines the mechanics of these materials and their various applications, covering topics such as variable stiffness, miniature-sized 4D printing, and more. Finally, the book includes a chapter on machine learning in 4D printing, with applications in mechanical, aerospace, civil and structural engineering, among others. Covers the mechanics, manufacturing processes and applications of 4D-printed smart materials and structures Discusses applications in civil, mechanical, aerospace, polymer and biomedical engineering Presents experimental, numerical and analytical studies in a simple and straightforward manner, providing tools that can be immediately implemented and adapted by readers to fit their work

This book discusses advanced materials and manufacturing processes with insights and overviews on tribology, automation, mechanical, biomedical, and aerospace engineering, as well as the optimization of industrial applications. The book explores the different types of composite materials while reporting on the design considerations and applications of each. Offering an overview of futuristic research areas, the book examines various engineering optimization and multi-criteria decision-making techniques and introduces a specific control framework used in analyzing processes. The book includes problem analyses and solving skills and covers different types of composite materials, their design considerations, and applications. This book is an informational resource for advanced undergraduate and graduate students, researchers, scholars, and field professionals, providing an update on the current advancements in the field of manufacturing processes.

This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.

4D Printing: Fundamentals and Applications explores both autonomic and non-autonomic systems with different stimulus such as temperature, current, moisture, light and sound. In addition, the fifth dimensional aspect using more than one stimulus is outlined for additive manufacturing processes. The book presents both an introduction to the basic understanding of hybrid processes and explores the physics behind the process (in the form of derivation and numerical problems). For the field engineer, applicable codes and standards for each hybrid process are provided. Lastly, case studies are included in each section to provide the reader with a model to explore future research directions. Begins with the fundamentals of the hybrid additive manufacturing process Presents a discussion of the physics behind smart material functioning in hybrid additive manufacturing Includes real world case studies on 4D and 5D printing, as well as a look at future research dimensions

In 1984, additive manufacturing represented a new methodology for manipulating matter, consisting of harnessing materials and/or energy to create three-dimensional physical objects. Today, additive manufacturing technologies represent a market of around 5 billion euros per year, with an annual growth between 20 and 30%. Different processes, materials and dimensions (from nanometer to decameter) within additive manufacturing techniques have led to 70,000 publications on this topic and to several thousand patents with applications as wide-ranging as domestic uses. Volume 1 of this series of books presents these different technologies with illustrative industrial examples. In addition to the strengths of 3D methods, this book also covers their weaknesses and the developments envisaged in terms of incremental innovations to overcome them.

This book addresses new challenges in soft matter and colloids. It presents timely reports on colloidal self-assembly, soft matters from liquid crystals, nanoparticles in liquid crystals, hydrocolloids, hybrid nanosystems, nanosuspensions, and dispersion of nanoparticles in different media, soft matter processing and modern experiments related with soft matters.

With a turnover of some 5-15 billion € / year, the additive manufacturing has industrial niches bearers thanks to processes and materials more and more optimized. While some niches still exist on the application of additive techniques in traditional fields (from jewelery to food for example), several trends emerge, using new concepts: collective production, realization of objects at once (without addition Of material), micro-fluidic, 4D printing exploiting programmable materials and materials, bio-printing, etc. There are both opportunities for new markets, promises not envisaged less than 10 years ago, but difficulties in reaching them.

3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine, Second Edition provides an in-depth introduction to bioprinting and nanotechnology and their industrial applications. Sections cover 4D Printing Smart Multi-responsive Structure, Cells for Bioprinting, 4D Printing Biomaterials, 3D/4D printing functional biomedical devices, 3D Printing for Cardiac and Heart Regeneration, Integrating 3D printing with Ultrasound for Musculoskeletal Regeneration, 3D Printing for Liver Regeneration, 3D Printing for Cancer Studies, 4D Printing Soft Bio-robots, Clinical Translation and Future Directions. The book's team of expert contributors have pooled their expertise in order to provide a summary of the suitability, sustainability and limitations of each technique for each specific application. The increasing availability and decreasing costs of nanotechnologies and 3D printing technologies are driving their use to meet medical needs. This book provides an overview of these technologies and their integration. Includes clinical applications, regulatory hurdles, and a risk-benefit analysis of each technology Assists readers in selecting the best materials and how to identify the right parameters for printing Includes the advantages of integrating 3D printing and nanotechnology in order to improve the safety of nano-scale materials for biomedical applications

This book contains select proceedings of the International Conference on Smart Technologies for Energy, Environment, and Sustainable Development (ICSTEESD 2020). The book is broadly divided into the themes of energy, environment, and sustainable development; and discusses the significance and solicitations of intelligent technologies in the domain of energy and environmental systems engineering. Topics covered in this book include sustainable energy systems including renewable technologies, energy efficiency, techno-economics of energy system and policies, integrated energy system planning, environmental management, energy efficient buildings and communities, sustainable transportation, smart manufacturing processes, etc. The book will be a valuable reference for young researchers, professionals, and policy makers working in the areas of energy, environment and sustainable development.

This new volume explores the exciting and diverse applications of three-dimensional printing in a variety of industries, including food processing, environmental sciences, biotechnology, medical devices, energy storage, civil engineering, the textile and fashion industry, and more. It describes the various 3D printing methods, the commonly used materials, and the pros and cons. It also presents an overview of the historical development and modern-day trends in additive manufacturing, as well as an exploration of the prospects of 3D printing technology in promoting academic education.

This second edition provides a comprehensive discussion of contemporary materials used in biomedical research and development. The pedagogical writing style and structure provides students with an understanding of the fundamental concepts necessary to pursue research and industrial work in this growing area of biomedical science, including characteristics of biomaterials, biological processes, biocompatibility, and applications of materials in implants and medical instruments. Written by leading researchers in the field, this volume highlights important topics associated with biomedical engineering, medicine and surgery. The revised text contains updates that reflect recent technological advances in biomedical materials. It contains information on new characterization methods and applications for biomedical materials and incorporates suggestions that were offered by readers and educators using the first edition over the years. This textbook takes the reader to the forefront of biomedical materials development, providing graduate students with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers.

Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS

Nanocellulose, a unique and promising natural material extracted from native cellulose, has received immense interest for its broad spectrum of applications owing to its remarkable physical properties, special surface chemistry, and excellent biological properties (biocompatibility, biodegradability and low toxicity). In attempts to meet the requirements of humanity's well-being, biomaterials scientists taking advantage of the structure and properties of nanocellulose aim to develop new and formerly non-existing materials with novel and multifunctional properties.This book highlights the importance of nanocellulose and reviews its synthesis, types, structure and properties. Further, it discusses various biofabrication approaches and applications of nanocellulose-based biomaterials in various fields such as the environment, biomedicine, optoelectronics, pharmaceutics, paper, renewable energy and the food industry. Devised to have a broad appeal, this book will be useful to beginners, who will appreciate its comprehensive approach, as well as active researchers, who will find the focus on recent advancements highly valuable.