Description : Essential for all biology and biomathematics courses, this textbook provides students with a fresh perspective of quantitative techniques in biology in a field where virtually any advance in the life sciences requires a sophisticated mathematical approach. An Invitation to Biomathematics, expertly written by a team of experienced educators, offers students a solid understanding of solving biological problems with mathematical applications. This text succeeds in enabling students to truly experience advancements made in biology through mathematical models by containing computer-based hands-on laboratory projects with emphasis on model development, model validation, and model refinement. The supplementary work, Laboratory Manual of Biomathematics is available separately ISBN 0123740223, or as a set ISBN: 0123740290) * Provides a complete guide for development of quantification skills crucial for applying mathematical methods to biological problems * Includes well-known examples from across disciplines in the life sciences including modern biomedical research * Explains how to use data sets or dynamical processes to build mathematical models * Offers extensive illustrative materials * Written in clear and easy-to-follow language without assuming a background in math or biology * A laboratory manual is available for hands-on, computer-assisted projects based on material covered in the text
Description : Laboratory Manual of Biomathematics is a companion to the textbook An Invitation to Biomathematics. This laboratory manual expertly aids students who wish to gain a deeper understanding of solving biological issues with computer programs. It provides hands-on exploration of model development, model validation, and model refinement, enabling students to truly experience advancements made in biology by mathematical models. Each of the projects offered can be used as individual module in traditional biology or mathematics courses such as calculus, ordinary differential equations, elementary probability, statistics, and genetics. Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology . Mathematical topics include Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms. It includes more than 120 exercises derived from ongoing research studies. This text is designed for courses in mathematical biology, undergraduate biology majors, as well as general mathematics. The reader is not expected to have any extensive background in either math or biology. Can be used as a computer lab component of a course in biomathematics or as homework projects for independent student work Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology Mathematical topics include: Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms Includes more than 120 exercises derived from ongoing research studies
Description : Algebraic and Combinatorial Computational Biology introduces students and researchers to a panorama of powerful and current methods for mathematical problem-solving in modern computational biology. Presented in a modular format, each topic introduces the biological foundations of the field, covers specialized mathematical theory, and concludes by highlighting connections with ongoing research, particularly open questions. The work addresses problems from gene regulation, neuroscience, phylogenetics, molecular networks, assembly and folding of biomolecular structures, and the use of clustering methods in biology. A number of these chapters are surveys of new topics that have not been previously compiled into one unified source. These topics were selected because they highlight the use of technique from algebra and combinatorics that are becoming mainstream in the life sciences. Integrates a comprehensive selection of tools from computational biology into educational or research programs Emphasizes practical problem-solving through multiple exercises, projects and spinoff computational simulations Contains scalable material for use in undergraduate and graduate-level classes and research projects Introduces the reader to freely-available professional software Supported by illustrative datasets and adaptable computer code
Description : The authors introduce geomathematics as an active research area to a wider audience. Chapter 1 presents an introduction to the Earth as a system to apply scientific methods. Emphasis is laid on transfers from virtual models to reality and vice versa. In the second chapter geomathematics is introduced as a new scientific area which nevertheless has its roots in antiquity. The modern conception of geomathematics is outlined from different points of view and its challenging nature is described as well as its interdisciplinarity. Geomathematics is shown as the bridge between the real world and the virtual world. The complex mathematical tools are shown from a variety of fields necessary to tackle geoscientific problems in the mathematical language. Chapter 3 contains some exemplary applications as novel exploration methods. Particular importance is laid on the change of language when it comes to translate measurements to mathematical models. New solution methods like the multiscale mollifier technique are presented. Further applications discussed are aspects of reflection seismics. Chapter 4 is devoted to the short description of recent activities in geomathematics. The Appendix (Chapter 5) is devoted to the GEM – International Journal on Geomathematics founded ten years ago. Besides a detailed structural analysis of the editorial goals an index of all papers published in former issues is given.
Description : Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. Examines significant questions in modern biology and their mathematical treatments Presents important mathematical concepts and tools in the context of essential biology Features material of interest to students in both mathematics and biology Presents chapters in modular format so coverage need not follow the Table of Contents Introduces projects appropriate for undergraduate research Utilizes freely accessible software for visualization, simulation, and analysis in modern biology Requires no calculus as a prerequisite Provides a complete Solutions Manual Features a companion website with supplementary resources
Description : Mathematical Concepts and Methods in Modern Biology offers a quantitative framework for analyzing, predicting, and modulating the behavior of complex biological systems. The book presents important mathematical concepts, methods and tools in the context of essential questions raised in modern biology. Designed around the principles of project-based learning and problem-solving, the book considers biological topics such as neuronal networks, plant population growth, metabolic pathways, and phylogenetic tree reconstruction. The mathematical modeling tools brought to bear on these topics include Boolean and ordinary differential equations, projection matrices, agent-based modeling and several algebraic approaches. Heavy computation in some of the examples is eased by the use of freely available open-source software. Features self-contained chapters with real biological research examples using freely available computational tools Spans several mathematical techniques at basic to advanced levels Offers broad perspective on the uses of algebraic geometry/polynomial algebra in molecular systems biology