Advanced Techniques in Diagnostic Microbiology

Advanced Techniques in Diagnostic Microbiology
Author: Yi-Wei Tang,Charles W. Stratton
Publsiher: Springer
Total Pages: 541
Release: 2018-11-09
ISBN: 3319339001
Category: Medical
Language: EN, FR, DE, ES & NL

Advanced Techniques in Diagnostic Microbiology Book Excerpt:

In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.

Laboratory Diagnosis of Infectious Diseases

Laboratory Diagnosis of Infectious Diseases
Author: Paul G. Engelkirk,Janet L. Duben-Engelkirk
Publsiher: Lippincott Williams & Wilkins
Total Pages: 780
Release: 2008
ISBN: 9780781797016
Category: Medical
Language: EN, FR, DE, ES & NL

Laboratory Diagnosis of Infectious Diseases Book Excerpt:

Designed for associate-degree MLT/CLT programs and baccalaureate MT/CLS programs, this textbook presents the essentials of clinical microbiology. It provides balanced coverage of specific groups of microorganisms and the work-up of clinical specimens by organ system, and also discusses the role of the microbiology laboratory in regard to emerging infections, healthcare epidemiology, and bioterrorism. Clinical case studies and self-assessment questions show how to incorporate the information into everyday practice. More than 400 illustrations and visual information displays enhance the text. Essentials boxes, chapter outlines, key terms, summaries, and other study aids help students retain information. A bound-in CD-ROM includes additional review questions, case studies, and Web links.

Automation and Basic Techniques in Medical Microbiology

Automation and Basic Techniques in Medical Microbiology
Author: Santi M. Mandal
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN: 1071623729
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Automation and Basic Techniques in Medical Microbiology Book Excerpt:

Advanced Techniques in Diagnostic Microbiology

Advanced Techniques in Diagnostic Microbiology
Author: Yi-Wei Tang,Charles W. Stratton
Publsiher: Springer Science & Business Media
Total Pages: 540
Release: 2007-01-16
ISBN: 0387328920
Category: Medical
Language: EN, FR, DE, ES & NL

Advanced Techniques in Diagnostic Microbiology Book Excerpt:

Clinical microbiologists are engaged in the field of diagnostic microbiology to determine whether pathogenic microorganisms are present in clinical specimens collected from patients with suspected infections. If microorganisms are found, these are identified and susceptibility profiles, when indicated, are determined. During the past two decades, technical advances in the field of diagnostic microbiology have made constant and enormous progress in various areas, including bacteriology, mycology, mycobacteriology, parasitology, and virology. The diagnostic capabilities of modern clinical microbiology laboratories have improved rapidly and have expanded greatly due to a technological revolution in molecular aspects of microbiology and immunology. In particular, rapid techniques for nucleic acid amplification and characterization combined with automation and user-friendly software have significantly broadened the diagnostic arsenal for the clinical microbiologist. The conventional diagnostic model for clinical microbiology has been labor-intensive and frequently required days to weeks before test results were available. Moreover, due to the complexity and length of such testing, this service was usually directed at the hospitalized patient population. The physical structure of laboratories, staffing patterns, workflow, and turnaround time all have been influenced profoundly by these technical advances. Such changes will undoubtedly continue and lead the field of diagnostic microbiology inevitably to a truly modern discipline. Advanced Techniques in Diagnostic Microbiology provides a comprehensive and up-to-date description of advanced methods that have evolved for the diagnosis of infectious diseases in the routine clinical microbiology laboratory. The book is divided into two sections. The first techniques section covers the principles and characteristics of techniques ranging from rapid antigen testing, to advanced antibody detection, to in vitro nucleic acid amplification techniques, and to nucleic acid microarray and mass spectrometry. Sufficient space is assigned to cover different nucleic acid amplification formats that are currently being used widely in the diagnostic microbiology field. Within each technique, examples are given regarding its application in the diagnostic field. Commercial product information, if available, is introduced with commentary in each chapter. If several test formats are available for a technique, objective comparisons are given to illustrate the contrasts of their advantages and disadvantages. The second applications section provides practical examples of application of these advanced techniques in several "hot" spots in the diagnostic field. A diverse team of authors presents authoritative and comprehensive information on sequence-based bacterial identification, blood and blood product screening, molecular diagnosis of sexually transmitted diseases, advances in mycobacterial diagnosis, novel and rapid emerging microorganism detection and genotyping, and future directions in the diagnostic microbiology field. We hope our readers like this technique-based approach and your feedback is highly appreciated. We want to thank the authors who devoted their time and efforts to produce their chapters. We also thank the staff at Springer Press, especially Melissa Ramondetta, who initiated the whole project. Finally, we greatly appreciate the constant encouragement of our family members through this long effort. Without their unwavering faith and full support, we would never have had the courage to commence this project.

Textbook of Diagnostic Microbiology E Book

Textbook of Diagnostic Microbiology   E Book
Author: Connie R. Mahon,Donald C. Lehman,George Manuselis
Publsiher: Elsevier Health Sciences
Total Pages: 1104
Release: 2014-04-11
ISBN: 0323292615
Category: Medical
Language: EN, FR, DE, ES & NL

Textbook of Diagnostic Microbiology E Book Book Excerpt:

Providing a solid introduction to the essentials of diagnostic microbiology, this accessible, full-color text helps you develop the problem-solving skills necessary for success in the clinical setting. A reader-friendly, "building block" approach to microbiology moves progressively from basic concepts to advanced understanding, guiding you through the systematic identification of etiologic agents of infectious diseases. Building block approach encourages recall of previously learned information, enhancing your critical and problem solving skills. Case in Point feature introduces case studies at the beginning of each chapter. Issues to Consider encourages you to analyze and comprehend the case in point. Key Terms provide a list of the most important and relevant terms in each chapter. Objectives give a measurable outcome to achieve by completing the material. Points to Remember summarize and help clearly identify key concepts covered in each chapter. Learning assessment questions evaluate how well you have mastered the material. New content addresses bone and joint infections, genital tract infections, and nosocomial infections. Significantly updated chapter includes current information on molecular biology and highlights content on multidrug resistant bacteria. Reorganized chapters accent the most relevant information about viruses and parasites that are also transmissible to humans. Case studies on the Evolve site let you apply the information that you learn to realistic scenarios encountered in the laboratory.

Automation In Clinical Microbiology

Automation In Clinical Microbiology
Author: James Wallace Jorgenson
Publsiher: CRC Press
Total Pages: 238
Release: 2018-01-18
ISBN: 1351078445
Category: Science
Language: EN, FR, DE, ES & NL

Automation In Clinical Microbiology Book Excerpt:

The chapters of this book describe numerous successful examples of automation in microbiology, e.g., radiometric detection of bacteremia, instruments for detection of bacteriuria, machines for organism identification and susceptibility testing, and automated antigen and antibody measurement systems. In addition, there are discussions of exciting but not yet proven methodologies such as chromatography, flow cytometry, and other applications of radiometry. There are also important discussions regarding improved means of data communication and ways to improve the clinician‘s use of test results. Lastly, there are candid assessments of the best and worst aspects of the current spectrum of automated instruments for microbiology. It is hoped that the reader of this volume will be left with a feeling of excitement at the possibilities that lie ahead for application of instrument techniques in the diagnosis of infectious diseases.

Introduction to Diagnostic Microbiology for the Laboratory Sciences

Introduction to Diagnostic Microbiology for the Laboratory Sciences
Author: Maria Dannessa Delost
Publsiher: Jones & Bartlett Publishers
Total Pages: 587
Release: 2014-03-11
ISBN: 1284032310
Category: Medical
Language: EN, FR, DE, ES & NL

Introduction to Diagnostic Microbiology for the Laboratory Sciences Book Excerpt:

Introduction to Diagnostic Microbiology for the Laboratory Sciences provides a foundation in microbiology that is essential for a career as a medical laboratory technologist/technician (MLT). A key text for students and a helpful reference for practitioners, it reviews the microorganisms most commonly encountered in clinical settings and clearly explains basic laboratory procedures. This text provides a concise overview of topics and facilitates comprehension with learning objectives, key terms, case studies, and review questions. In addition, the text includes laboratory exercises, eliminating the need for a separate laboratory manual. Covering content required in the MLT curriculum and featured on the certification exam, this accessible text will help prepare students for a career in laboratory science. Key Features - Reviews the microorganisms most important in clinical practice - Explains basic laboratory procedures, such as specimen collection and staining - Includes laboratory exercises in the text-no need for a separate manual - Serves as a helpful on-the-job reference for laboratory practitioners - Provides practice questions to help students prepare for the medical technology certification exam CHAPTER PEDAGOGY: Chapter Outline, Key Terms, Learning Objectives, Procedures, Laboratory Exercises, Case Studies, Review Questions INSTRUCTOR RESOURCES: Image Bank with 247 photos and illustrations; PowerPoint Presentations per chapter; Laboratory Exercise Worksheets; and a Test Bank with 450 multiple choice questions and a 225-question exam. Introduction to Diagnostic Microbiology for the Laboratory Sciences is on the recommended reading list to prepare for the ASCP MLT exam. (American Society for Clinical Pathology, Medical Laboratory Technician exam)

Rapid Methods and Automation in Microbiology and Immunology

Rapid Methods and Automation in Microbiology and Immunology
Author: K.-O. Habermehl
Publsiher: Springer Science & Business Media
Total Pages: 730
Release: 2012-12-06
ISBN: 364269943X
Category: Medical
Language: EN, FR, DE, ES & NL

Rapid Methods and Automation in Microbiology and Immunology Book Excerpt:

Rapid progress in molecular biology, genetic engineering, and basic research in immunology has opened up new possibilities for application to diagnostic procedures and to clinical research. In a short period a new era of diagnosis dawned, covering nearly all fields of microbiology, immunology, and food technology. In consequence of this rapid development, scientists of many disciplines are involved studying infections of humans, animals, and plants or working in technical microbiology. The application of the newest findings of basic research to diagnostic work and to clinical research covers nearly all fields of microbiology and immunology. Moreover, it underlines the close relationship between diagnosis, therapy, and epidemiology. An outstanding example of these connections is given by the recent development of hepatitis B vaccine. The discovery and identification of a non cultivable agent by physicochemical and immunological methods were the heralds of a new era in the prevention of infectious diseases. This book provides an up-to-date, comprehensive review of developments and future aspects in various fields. I am convinced that the authors have succeeded in furnishing a large variety of new ideas and possibilities. K.-O. HABERMEHL Contents Time Realities in the Evaluation of Vaccines for Safety and Efficacy The Evaluation of Vaccines M. R. HILLEMAN . . . . .

Automation and Emerging Technology in Clinical Microbiology An Issue of Clinics in Laboratory Medicine

Automation and Emerging Technology in Clinical Microbiology  An Issue of Clinics in Laboratory Medicine
Author: Carey-Ann D. Burnham
Publsiher: Elsevier Health Sciences
Total Pages: 352
Release: 2013-08-14
ISBN: 0323188613
Category: Medical
Language: EN, FR, DE, ES & NL

Automation and Emerging Technology in Clinical Microbiology An Issue of Clinics in Laboratory Medicine Book Excerpt:

The field of Clinical Microbiology is evolving at a rapid pace, perhaps more so than any other arm of laboratory medicine. This can be attributed to new technology, including high throughput gene sequencing, multiplex molecular assays, rapid evolution of antimicrobial resistance, and discovery of new pathogens. In addition, modern medical procedures, such as solid organ and stem cell transplantation, have resulted in an explosion of infections with agents that historically have been considered to be of low virulence. This issue of Clinics in Laboratory Medicine will highlight some of the advances in diagnostic microbiology, including MALDI-TOF MS, pathogen discovery, and personalized antimicrobial chemotherapy. In addition, one of the papers will focus on implementation of new technologies and how to maximize patient impact of these new methods.

Rapid Methods and Automation in Microbiology and Immunology

Rapid Methods and Automation in Microbiology and Immunology
Author: Antti Vaheri,Richard C. Tilton,Albert Balows
Publsiher: Springer Science & Business Media
Total Pages: 573
Release: 2012-12-06
ISBN: 364276603X
Category: Medical
Language: EN, FR, DE, ES & NL

Rapid Methods and Automation in Microbiology and Immunology Book Excerpt:

The current diagnostic methods for the great variety of microbial agents affecting health are clearly unsatisfactory. New important pathogens have emerged including the agent responsible for bovine spongiform encephalopathy. Moreover, there is an increasing need for more accurate microbial control of our environment, and of the food and water we consume. What is needed are rapid, sensitive and reliable procedures which, on the one hand, should be suitable for automation and, onthe other hand, presented in a cost-effective version suitable for field use. Including new biochemical approaches, such as polymerase chain reaction, recombinant gene products and synthetic peptides, these needs are discussed in these protocols of the RAMI-90 congress.

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 1472
Release: 1976
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Excerpt:

Diagnostic Bacteriology Protocols

Diagnostic Bacteriology Protocols
Author: Louise O’Connor
Publsiher: Springer Science & Business Media
Total Pages: 226
Release: 2008-02-05
ISBN: 1597451436
Category: Science
Language: EN, FR, DE, ES & NL

Diagnostic Bacteriology Protocols Book Excerpt:

The field of bacterial diagnostics has seen unprecedented advances in recent years. The increased need for accurate detection and identification of bacteria in human, animal, food, and environmental samples has fueled the development of new techniques. The field has seen extensive research aided by the information from bacterial genome sequencing projects. Although traditional methods of bacterial detection and identification remain in use in laboratories around the world, there is now a growing trend toward the use of nucleic ac- based diagnostics and alternative biochemically and immunologically based formats. The ultimate goal of all diagnostic tests is the accurate detection, identification, or typing of microorganisms in samples of interest. Although the resulting information is of obvious use in the areas of patient management, animal health, and quality control, it is also of use in monitoring routes of infection and outlining strategies for infection control. There is, therefore, a need to ensure that the information being provided is of the highest standard and that any new technique is capable of delivering this.

Microbial Food Contamination

Microbial Food Contamination
Author: Charles L. Wilson Ph.D.
Publsiher: CRC Press
Total Pages: 632
Release: 2007-10-08
ISBN: 1420008471
Category: Medical
Language: EN, FR, DE, ES & NL

Microbial Food Contamination Book Excerpt:

Divided into five parts, Microbial Food Contamination, Second Edition looks at emerging foodborne human pathogens andcomprehensively evaluates the microbiology, biochemistry, detection, risk, and threat of foodborne illness in today's global market. The first section introduces new insights into the pathogenic effect of E. coli, viral

Bailey Scott s Diagnostic Microbiology E Book

Bailey   Scott s Diagnostic Microbiology   E Book
Author: Patricia Tille
Publsiher: Elsevier Health Sciences
Total Pages: 1056
Release: 2013-08-13
ISBN: 032327742X
Category: Medical
Language: EN, FR, DE, ES & NL

Bailey Scott s Diagnostic Microbiology E Book Book Excerpt:

Known as the #1 bench reference for practicing microbiologists and an excellent text for students in clinical laboratory science programs, Bailey & Scott’s Diagnostic Microbiology, 13th Edition helps you develop and refine the skills you need for effective laboratory testing. In-depth information is useful and easily accessible, with step-by-step instructions for all the procedures. This edition features more than 20 NEW chapters plus updated material on the newest advances and the latest trends in clinical microbiology. Written by expert Dr. Patricia Tille, this classic reference addresses the topics and issues most relevant to you and your success on the job. Hands-on procedures include step-by-step instructions, full-color photos, and expected results, helping you achieve more accurate results. Case studies give you the opportunity to apply your skills in a variety of diagnostic scenarios and help improve your decision-making and critical thinking skills. Genera and Species to be Considered boxes highlight all of the organisms to be discussed in each chapter, including the current name of the species as well as any previous names. Student resources on Evolve enhance your learning with review questions and procedures. Convenient, easy-to-read tables summarize key information. Detailed, full-color illustrations aid comprehension and help you visualize concepts. A glossary of terms is found at the back of the book for quick reference. NEW! Learning objectives begin each chapter, giving you a measurable outcome to achieve by the completing the material. NEW! Review questions on the Evolve companion website are tied to learning objectives, and enhance your understanding and retention of chapter content. NEW! Reader-friendly chapters cover groups of related organisms rather than addressing all at once, including the parasitology, mycology, and virology chapters.

Encyclopedia of Microbiology

Encyclopedia of Microbiology
Author: Thomas M. Schmidt
Publsiher: Academic Press
Total Pages: 3199
Release: 2019-09-11
ISBN: 0128117370
Category: Science
Language: EN, FR, DE, ES & NL

Encyclopedia of Microbiology Book Excerpt:

Encyclopedia of Microbiology, Fourth Edition gathers both basic and applied dimensions in this dynamic field that includes virtually all environments on Earth. This range attracts a growing number of cross-disciplinary studies, which the encyclopedia makes available to readers from diverse educational backgrounds. The new edition builds on the solid foundation established in earlier versions, adding new material that reflects recent advances in the field. New focus areas include `Animal and Plant Microbiomes’ and ‘Global Impact of Microbes`. The thematic organization of the work allows users to focus on specific areas, e.g., for didactical purposes, while also browsing for topics in different areas. Offers an up-to-date and authoritative resource that covers the entire field of microbiology, from basic principles, to applied technologies Provides an organic overview that is useful to academic teachers and scientists from different backgrounds Includes chapters that are enriched with figures and graphs, and that can be easily consulted in isolation to find fundamental definitions and concepts

Advanced Techniques in Diagnostic Microbiology

Advanced Techniques in Diagnostic Microbiology
Author: Yi-Wei Tang,Charles W. Stratton
Publsiher: Springer Science & Business Media
Total Pages: 957
Release: 2012-09-13
ISBN: 1461439698
Category: Medical
Language: EN, FR, DE, ES & NL

Advanced Techniques in Diagnostic Microbiology Book Excerpt:

In the United States, hospitals annually report over 5 million cases of infectious-disease-related illnesses: clinical microbiology laboratories in these hospitals are engaged in detecting and identifying the pathogenic microorganisms in clinical specimens collected from these patients with suspected infections. Clearly, the timely and accurate detection/identification of these microbial pathogens is critical for patient treatment decisions and outcomes for millions of patients each year. Despite an appreciation that the outcome of an infectious-disease-related illness is directly related to the time required to detect and identify a microbial pathogen, clinical microbiology laboratories in the United States as well as worldwide have long been hampered by traditional culture-based assays, which may require prolonged incubation time for slowly growing microorganisms such as Mycobacterium tuberculosis. Moreover, traditional culture-based assays often require multiple steps with additional time needed for discernment of species and/or detection of antimicrobial resistance. Finally, these traditional, slow multistep culture-based assays are labor-intensive and required skilled clinical microbiologists at the bench. Over the past several decades, advanced molecular techniques in diagnostic microbiology quietly have been revolutionizing the practice of clinical microbiology in the hospital setting. Indeed, molecular diagnostic testing in general and nucleic-acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. There is no question that the development of rapid molecular techniques for nucleic acid amplification/characterization combined with automation and user-friendly software has greatly broadened the diagnostic capabilities of the clinical microbiology laboratory. These technical advances in molecular microbiology over the first decade of the 21st Century have profoundly influenced the physical structure of clinical microbiology laboratories as well as their staffing patterns, workflow, and turnaround time. These molecular microbiology advances have also resulted in the need for a revised and updated second edition of Advanced Techniques in Diagnostic Microbiology. This second edition again provides an updated and comprehensive description of the ongoing evolution of molecular methods for the diagnosis of infectious diseases. In addition, many new chapters have been added, including a chapter on the clinical interpretation and relevance of advanced technique results. The second edition, like the first edition, includes both a “techniques” section describing the latest molecular techniques and an “applications” section describing how these advanced molecular techniques are being used in the clinical setting. Finally, the second edition, like the first edition, utilizes a diverse team of authors who have compiled chapters that provide the reader with comprehensive and useable information on advanced molecular microbiology techniques.

Bailey Scott s Diagnostic Microbiology E Book

Bailey   Scott s Diagnostic Microbiology   E Book
Author: Patricia Tille
Publsiher: Elsevier Health Sciences
Total Pages: 1136
Release: 2015-12-28
ISBN: 0323428924
Category: Medical
Language: EN, FR, DE, ES & NL

Bailey Scott s Diagnostic Microbiology E Book Book Excerpt:

Perfect your lab skills with the gold standard in microbiology! Serving as both the #1 bench reference for practicing microbiologists and as a favorite text for students in clinical laboratory science programs, Bailey & Scott’s Diagnostic Microbiology, 14th Edition covers all the topical information and critical thinking practice you need for effective laboratory testing. This new edition also features hundreds step-by-step procedures, updated visuals, new case studies, and new material on the latest trends and equipment in clinical microbiology — including automation, automated streaking, MALDI-TOF, and incubator microscopes. It’s everything you need to get quality lab results in class and in clinical practice! More than 800 detailed, full-color illustrations aid comprehension and help in visualizing concepts. Expanded sections on parasitology, mycology, and virology eliminate the need to purchase separate books on this material. General and Species boxes in the organism chapters highlight the important topics that will be discussed in the chapter. Case studies provide the opportunity to apply information to a variety of diagnostic scenarios, and help improve decision-making and critical thinking skills. Hands-on procedures include step-by-step instructions, full-color photos, and expected results. A glossary of terms is found at the back of the book for quick reference. Learning objectives begin each chapter, offering a measurable outcome to achieve by the completing the material. Learning resources on the Evolve companion website enhance learning with review questions and procedures. NEW! Coverage of automation, automated streaking, MALDI-TOF, and incubator microscopes keeps you in the know on these progressing topics. NEW! Updated images provide a more vivid look into book content and reflect the latest procedures. NEW! Thoroughly reviewed and updated chapters equip you with the most current information. NEW! Significant lab manual improvements provide an excellent learning resource at no extra cost. NEW! 10 extra case studies on the Evolve companion website offer more opportunities to improve critical thinking skills.

Symposium on Automation in Microbiology

Symposium on Automation in Microbiology
Author: Anonim
Publsiher: Unknown
Total Pages: 180
Release: 1975
ISBN: 1928374650XXX
Category: Microbiology
Language: EN, FR, DE, ES & NL

Symposium on Automation in Microbiology Book Excerpt:

The Role of Modern Technology in Food Inspection

The Role of Modern Technology in Food Inspection
Author: United States,United States. Congress. House. Committee on Science, Space, and Technology. Subcommittee on Technology, Environment, and Aviation
Publsiher: Unknown
Total Pages: 322
Release: 1994
ISBN: 1928374650XXX
Category: Food
Language: EN, FR, DE, ES & NL

The Role of Modern Technology in Food Inspection Book Excerpt:

Automation Genomic and Functional Analyses

Automation  Genomic and Functional Analyses
Author: Anonim
Publsiher: Academic Press
Total Pages: 270
Release: 1999-02-15
ISBN: 9780121948603
Category: Science
Language: EN, FR, DE, ES & NL

Automation Genomic and Functional Analyses Book Excerpt:

Automation is the major future trend for many areas in microbiology, molecular biology, and biochemistry, among other disciplines. It is an enormously exciting area, where techniques and assays that were once repetitive, tedious, and time consuming can be performed robotically, liberating the time of researchers and hospital laboratory workers for more interesting work. Many techniques have now been automated and often miniaturized, including PCR analysis, DNA/RNA preparation, diagnostic test (e.g., Pap tests), compound screening, and of course, sequencing. Some major advances, notably in Professor Leroy Hood's group, have resulted in the ability to perform thousands of assays simultaneously on a normal microscope slide. Automation, edited by two of the leading experts in the field, presents the very latest experimental techniques explained in detail. This book has succeeded in bringing together researchers at the forefront of clone library construction, genome analysis, sequencing, computational data evaluation and functional analysis, to provide insight into this "new age" of research based on genomic and chemical screening. Describes automated procedures used in microbiology and molecular biology Includes developments in robotics and vision systems Features automation in library picking, presentation and analysis Discusses paralogous duplications in microbial genomes Covers deciphering genomes through automated large-scale sequencing Describes and stresses the need for functional analyses Internationally acclaimed contributors, including Professor Leroy Hood