Bioconjugate Techniques

Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Written by two leading experts in the field, Bioconjugation offers invaluable guidance for the design of protein conjugates of all types, covering the coupling of proteins to organic molecules, nucleic acids and solid phases as well as other proteins. Its comprehensive coverage saves time by bringing together information previously available only form a wide variety of sources. An essential reference for college and university libraries supporting research in biochemistry, immunology and medicine.

These proceedings of the 4th International Conference on Mechanical and Electrical Technology (ICMET 2012), held during the 24 to 26th July 2012 in Kuala Lumpur, Malaysia, take the form of 614 peer-reviewed papers grouped as follows: Materials Engineering; Applied Mechanics and Mechanical Engineering; Electrotechnics and Electrical Machines; Energy and Power Engineering; Measurements, Monitoring and Sensors; Electronic and Radio Engineering; Computer-Aided Design and Technology; Control and Automation; Manufacturing Processes and Technology.

Offering a unique mix of practical information on immunoassay technology coupled with a review of clinical applications, the Second Edition of this successful reference work is an invaluable source of information. It describes the underlying principles of immunoassay, evaluates major diagnostic products, provides a complete analysis of practical laboratory management, and concludes with an extensive review of immunoassay technology applications in clinical situations. With almost 90 contributing authors, The Immunoassay Handbook offers an authoritative international analysis of contemporary immunoassay.Each of the book's four sections has been expanded and updated from the previous edition: Principles: An overview of the general theory of immunoassay.Products: Details the major diagnostic machinery currently available, outlining features, background theory and development, objective feedback, and comparison between products.Laboratory Management: Including information on sample preparation, quality, troubleshooting, laboratory automation, and laboratory information systems.Applications: of immunoassay technology in clinical situations (which technologies to use in AIDS testing, for example) with theory and background material, as well as key references.Essential reading for clinical chemists and biochemists in medical and biological research laboratories, the Handbook will also be invaluable for marketing and sales staff, and research and development staff at immunoassay manufacturers and distributors. In addition, the book will be useful for students of immunology, biochemistry and medicine.

This text covers methods for detecting and monitoring pollution in air, soil and water in the context of legal requirements and industry standards. Methods covered include biosensors and remote sensing, with practical guidance on their use included.

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

The MRS Symposium Proceeding series is an internationally recognised reference suitable for researchers and practitioners.