Biomechanics of Coronary Atherosclerotic Plaque

Biomechanics of Coronary Atherosclerotic Plaque
Author: Anonim
Publsiher: Academic Press
Total Pages: 686
Release: 2020-03-15
ISBN: 0128171960
Category: Science
Language: EN, FR, DE, ES & NL

Biomechanics of Coronary Atherosclerotic Plaque Book Excerpt:

Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, Fourth Edition summarizes all biomechanical aspects of each living organ in one comprehensive reference. The first two volumes introduce Continuum Fluid and Solid Biomechanics approaches, with each subsequent volume covering the important biomechanical and clinical aspects. The key thought leaders in the field of Biomechanics of Living Organs have gathered together their expertise in this series, making it an essential reference for anyone working in this research area. This book presents the first such resource to cover fluid and solid biomechanical studies conducted in this last decade to increase our understanding of plaque initiation, growth and rupture and improve the design of medical devices and clinical interventions, including surgical procedures. Presents the main computational fluid dynamic studies performed, describing blood flow in healthy and pathological artery branches, including in coronary bifurcations Highlights the correlation between plaque initiation regions and blood shear stress amplitude Discusses the main biomechanical and mechanobiological models to highlight the importance of quantifying the residual and peak cap stresses and the presence of μ-calcifications to evaluate the risk of plaque rupture Introduces the most recent intravascular imaging biomarker techniques (elastography, palpography and modulography)

Biomechanics of Coronary Atherosclerotic Plaque

Biomechanics of Coronary Atherosclerotic Plaque
Author: Anonim
Publsiher: Academic Press
Total Pages: 518
Release: 2020-07-15
ISBN: 9780128240472
Category: Science
Language: EN, FR, DE, ES & NL

Biomechanics of Coronary Atherosclerotic Plaque Book Excerpt:

Vascular Biomechanics

Vascular Biomechanics
Author: T. Christian Gasser
Publsiher: Springer Nature
Total Pages: 608
Release: 2022-02-14
ISBN: 3030709663
Category: Sports & Recreation
Language: EN, FR, DE, ES & NL

Vascular Biomechanics Book Excerpt:

This textbook serves as a modern introduction to vascular biomechanics and provides the comprehensive overview of the entire vascular system that is needed to run successful vascular biomechanics simulations. It aims to provide the reader with a holistic analysis of the vascular system towards its biomechanical description and includes numerous fully through-calculated examples. Various topics covered include vascular system descriptions, vascular exchange, blood vessel mechanics, vessel tissue characterization, blood flow mechanics, and vascular tissue growth and remodeling. This textbook is ideally suited for students and researchers studying and working in classical and computational vascular biomechanics. The book could also be of interest to developers of vascular devices and experts working with the regulatory approval of biomedical simulations. Follows the principle of “learning by doing” and provides numerous fully through-calculated examples for active learning, immediate recall, and self-examination; Provides a holistic understanding of vascular functioning and the integration of information from different disciplines to enable students to use sophisticated numerical methods to simulate the response of the vascular system; Includes several case studies that integrate the presented material. Case studies address problems, such as the biomechanical rupture risk assessment of Abdominal Aortic Aneurysms, Finite Element analysis of structural and blood flow problems, the computation of wall stress and wall shear stress in the aorta.

Plaque Imaging

Plaque Imaging
Author: Jasjit S. Suri
Publsiher: IOS Press
Total Pages: 461
Release: 2005-01-01
ISBN: 1586035169
Category: Medical
Language: EN, FR, DE, ES & NL

Plaque Imaging Book Excerpt:

This publication starts of with a review of plaque imaging techniques, with an introduction of the segmentation techniques for plaque classification and quantification. Many aspects of plaque imaging techniques are presented in this publication, such as; medical image retrieval and database management, MRI techniques to differentiate stable versus high risk atherosclerosis, composition and morphology of atherosclerotic plaque, analysis of the soft tissue based on computer vision techniques, modelling of coronary artery biomechanics, Cardiac CT for the assessment of cardiovascular pathology with an emphasis on the detection of coronary atherosclerosis, technical and practical issues regarding coronary atherosclerotic plaque imaging by CT (focussing on coronary calcium imaging), feasibility of a non-invasive, in vivo determination of the IBS of arterial wall tissue, high resolution ultrasound images of carotid plaques, the problem of reliable features extraction and classification process and a discussion on advanced mathematical techniques to extract spectral information from the RF data to determine the plaque composition.

Multiscale Modeling to Tackle the Complexity of Load Bearing Organ and Tissue Regulation

Multiscale Modeling to Tackle the Complexity of Load Bearing Organ and Tissue Regulation
Author: Jerome Noailly,Stephane Avril,Peter Pivonka,Stefan Scheiner
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-03-11
ISBN: 2889746623
Category: Science
Language: EN, FR, DE, ES & NL

Multiscale Modeling to Tackle the Complexity of Load Bearing Organ and Tissue Regulation Book Excerpt:

Cardiovascular Calcification and Bone Mineralization

Cardiovascular Calcification and Bone Mineralization
Author: Elena Aikawa,Joshua D. Hutcheson
Publsiher: Springer Nature
Total Pages: 563
Release: 2020-07-01
ISBN: 3030467252
Category: Medical
Language: EN, FR, DE, ES & NL

Cardiovascular Calcification and Bone Mineralization Book Excerpt:

The book covers the basic science and clinical aspects of cardiovascular calcification and bone mineralization. Cardiovascular calcification is the leading predictor of cardiovascular morbidity and mortality, with a predictive value more significant than blood lipid levels. The presence of calcific mineral in cardiovascular tissues alters biomechanical performance, increasing workload on the heart and potentiating atherosclerotic plaque rupture and subsequent heart attack and stroke. This book examines the role of calcification in cardiovascular disease covering topics such as calcification in the atherosclerotic plaques and aortic valves arteries and valves, aortic valve replacement, peripheral artery disease, imaging of early calcification and target discovery. In addition, various forms of ectopic calcification as well as mechanisms of bone mineralization are discussed. Cardiovascular Calcification and Bone Mineralization is an essential resource for clinicians, researchers, and other medical professionals in cardiology, pathology, and biomedical engineering.

Plaque Imaging Pixel to Molecular Level

Plaque Imaging  Pixel to Molecular Level
Author: J.S. Suri,C. Yuan,D.L. Wilson
Publsiher: IOS Press
Total Pages: 488
Release: 2005-05-27
ISBN: 1607501163
Category: Computers
Language: EN, FR, DE, ES & NL

Plaque Imaging Pixel to Molecular Level Book Excerpt:

Coronary disease is the number one cause of death in the United States and the Western world and approximately 250,000 affected people die per year without being admitted to the hospital. One of the main reasons of such a high death rate without any diagnostics in more than 50% of myocardial infarctions (MIs or heart attacks) occur in patients with no prior history of heart attack disease or symptoms. Coronary artery disease leads to the occlusion of arteries that are vital in providing nutrients to the heart muscles. The disease develops by progressive accumulation or formation of 'plaque' within an artery. Certain types of arteries could occlude blood flow and yet might be 'stable'. These plaques usually have high fibrous content and are known as hard plaques. On the other hand, 'unstable or soft plaques' might not cause much occlusion but could be venerable to rupture. Rupture of such plaques could lead to total or partial occlusion in arteries resulting in sudden cardiac death or heart attack. In fact, 68% of the MIs are caused by rupture of plaques when coronary arteries are less than 50% occluded. This book is about plaque imaging covering both clinical and imaging aspects of plaque using Magnetic Resonance (MR), Computer Tomography (CT), Intravascular Ultrasound (IVUS), Elastography and at Molecular/Microscopic levels.

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging
Author: Lambros S Athanasiou,Dimitrios I Fotiadis,Lampros K Michalis
Publsiher: Academic Press
Total Pages: 234
Release: 2017-05-04
ISBN: 0128051132
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging Book Excerpt:

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and characterization. The authors, with their expertise from biomedical engineering, computer science, and cardiology, offer a holistic view. The focus of the book is on the presentation of major imaging techniques, including their limitations. It includes details on the mechanical characterization and properties of plaques and appropriate constitutive models to describe the mechanical behavior of plaques. The authors explore the challenges of using multiple coronary imaging technologies, and provide the pros and cons of invasive vs. non-invasive techniques. Methods for plaque characterization and 3D reconstruction of coronary arteries using IVUS, OCT, and CT images are described. This book will help readers study new trends in image processing analysis and plaque characterization, implement automated plaque characterization methodologies, understand coronary imaging drawbacks, and comprehend 3 dimensional coronary artery and plaque reconstruction methods. Describes the multimodality imaging techniques that are commonly used in the diagnosis of arterial diseases, including intravascular ultrasound, optical coherence tomography, angiography, computed tomography angiography, and magnetic resonance angiography Discusses in-depth the computational methods which can be used for the detection of different plaque types Explores plaque in 3D reconstruction methods and plaque modeling approaches

Computational Biomechanics for Medicine

Computational Biomechanics for Medicine
Author: Adam Wittek,Grand Joldes,Poul M.F. Nielsen,Barry J. Doyle,Karol Miller
Publsiher: Springer
Total Pages: 173
Release: 2017-04-29
ISBN: 3319544810
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Computational Biomechanics for Medicine Book Excerpt:

This volume comprises the latest developments in both fundamental science and patient-specific applications, discussing topics such as: cellular mechanics; injury biomechanics; biomechanics of heart and vascular system; medical image analysis; and both patient-specific fluid dynamics and solid mechanics simulations. With contributions from researchers world-wide, the Computational Biomechanics for Medicine series of titles provides an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements.

Biomechanics Trends in Modeling and Simulation

Biomechanics  Trends in Modeling and Simulation
Author: Gerhard A. Holzapfel,Ray W. Ogden
Publsiher: Springer
Total Pages: 316
Release: 2016-09-14
ISBN: 3319414755
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Biomechanics Trends in Modeling and Simulation Book Excerpt:

The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.

Computational Biomechanics of the Heart and Vasculature with Potential Clinical and Surgical Applications

Computational Biomechanics of the Heart and Vasculature with Potential Clinical and Surgical Applications
Author: Dalin Tang,Estefania Peña,Daniela Valdez-Jasso,Zhiyong Li,Youjun Liu
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-05-03
ISBN: 2889760448
Category: Science
Language: EN, FR, DE, ES & NL

Computational Biomechanics of the Heart and Vasculature with Potential Clinical and Surgical Applications Book Excerpt:

Multiscale Modeling in Biomechanics and Mechanobiology

Multiscale Modeling in Biomechanics and Mechanobiology
Author: Suvranu De,Wonmuk Hwang,Ellen Kuhl
Publsiher: Springer
Total Pages: 286
Release: 2014-10-10
ISBN: 1447165993
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Multiscale Modeling in Biomechanics and Mechanobiology Book Excerpt:

Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Multi Modality Atherosclerosis Imaging and Diagnosis

Multi Modality Atherosclerosis Imaging and Diagnosis
Author: Luca Saba,João Miguel Sanches,Luís Mendes Pedro,Jasjit S. Suri
Publsiher: Springer Science & Business Media
Total Pages: 422
Release: 2013-09-13
ISBN: 1461474256
Category: Medical
Language: EN, FR, DE, ES & NL

Multi Modality Atherosclerosis Imaging and Diagnosis Book Excerpt:

Stroke is one of the leading causes of death in the world, resulting mostly from the sudden ruptures of atherosclerosis carotid plaques. Understanding why and how plaque develops and ruptures requires a multi-disciplinary approach such as radiology, biomedical engineering, medical physics, software engineering, hardware engineering, pathological and histological imaging. Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment presents a new dimension of understanding Atherosclerosis in 2D and 3D. This book presents work on plaque stress analysis in order to provide a general framework of computational modeling with atherosclerosis plaques. New algorithms based on 3D and 4D Ultrasound are presented to assess the atherosclerotic disease as well as very recent advances in plaque multimodality image fusion analysis. The goal of Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment is to fuse information obtained from different 3D medical image modalities, such as 3D US, CT and MRI, providing the medical doctor with some sort of augmented reality information about the atherosclerotic plaque in order to improve the accuracy of the diagnosis. Analysis of the plaque dynamics along the cardiac cycle is also a valuable indicator for plaque instability assessment and therefore for risk stratification. 4D Ultrasound, a sequence of 3D reconstructions of the region of interest along the time, can be used for this dynamic analysis. Multimodality Image Fusion is a very appealing approach because it puts together the best characteristics of each modality, such as, the high temporal resolution of US and the high spatial resolutions of MRI and CT.

Atherosclerosis Disease Management

Atherosclerosis Disease Management
Author: Jasjit S. Suri,Chirinjeev Kathuria,Filippo Molinari
Publsiher: Springer Science & Business Media
Total Pages: 944
Release: 2010-11-16
ISBN: 1441972226
Category: Medical
Language: EN, FR, DE, ES & NL

Atherosclerosis Disease Management Book Excerpt:

Atherosclerosis is a degenerative process affecting blood vessels, which determines narrowing of the lumen, plaque growth, and hardening of the walls. It is a risk factor for cardiovascular diseases. The focus of this book is on the management of the atherosclerotic disease. The coverage of this book spans from histological presentation of the various stages of atherosclerotic lesions to the earliest studies in atherosclerosis therapy, from advanced clinical diagnosis to monitoring, follow-up, and home-care of the atherosclerotic patient. The book shows well-established diagnostic techniques covering several medical imaging modalities such as Ultrasounds, IVUS, MRI, Computer Tomography, along with new trends in early and advanced atherosclerosis diagnosis (innovative drugs and tissue characterization procedures). Surgical standards will be presented along with innovative experimental trials for the treatment of the atherosclerotic patient. The book will also cover emerging techniques based on molecular imaging and vibro-acoustics.

Cardiovascular Biomechanics

Cardiovascular Biomechanics
Author: Peter R. Hoskins,Patricia V. Lawford,Barry J. Doyle
Publsiher: Springer
Total Pages: 462
Release: 2017-02-16
ISBN: 3319464078
Category: Medical
Language: EN, FR, DE, ES & NL

Cardiovascular Biomechanics Book Excerpt:

This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.

Biomechanical Modelling at the Molecular Cellular and Tissue Levels

Biomechanical Modelling at the Molecular  Cellular and Tissue Levels
Author: Gerhard A. Holzapfel,Ray W. Ogden
Publsiher: Springer Science & Business Media
Total Pages: 344
Release: 2009-06-05
ISBN: 3211958754
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Biomechanical Modelling at the Molecular Cellular and Tissue Levels Book Excerpt:

J.D. Humphrey: Need for a Continuum Biochemomechanical Theory of Soft Tissue and Cellular Growth and Remodeling H. Schmid and P.J. Hunter: Multi-scale Modelling of the Heart R.W. Ogden: Anisotropy and Nonlinear Elasticity in Arterial Wall Mechanics G.A. Holzapfel: Arterial Tissue in Health and Disease: Experimental Data, Collagen-based Modeling and Simulation, Including Aortic Dissection.

Biomechanics of Living Organs

Biomechanics of Living Organs
Author: Yohan Payan,Jacques Ohayon
Publsiher: Academic Press
Total Pages: 602
Release: 2017-06-09
ISBN: 0128040602
Category: Science
Language: EN, FR, DE, ES & NL

Biomechanics of Living Organs Book Excerpt:

Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics. Covers hyper elastic frameworks for large tissue deformations Considers which strain energy functions are the most appropriate to model the passive and active states of living tissue Evaluates the physical meaning of proposed energy functions

Intravascular Ultrasound

Intravascular Ultrasound
Author: Balocco Simone
Publsiher: Elsevier
Total Pages: 218
Release: 2020-06-06
ISBN: 0128188340
Category: Computers
Language: EN, FR, DE, ES & NL

Intravascular Ultrasound Book Excerpt:

Intravascular Ultrasound: From Acquisition to Advanced Quantitative Analysis covers topics of the whole imaging pipeline, ranging from the definition of the clinical problem and image acquisition systems to image processing and analysis, including the assisted clinical-decision making procedures and treatment planning (stent deployment and follow up). Atherosclerosis, a disease of the vessel wall that produces vessel narrowing and obstruction, is the major cause of cardiovascular diseases, such as heart attack or stroke. This book covers all aspects of this imaging tool that allows for the visualization of internal vessel structures and the quantification and characterization of coronary plaque. Provides an introduction to the clinical workflow and current challenges in endovascular interventions Presents a review of the state-of-the-art methodologies in IVUS imaging and their applications Includes a rich analysis of the current and potential future connections between the academic, clinical and industrial fields

Computational And Mathematical Methods In Cardiovascular Physiology

Computational And Mathematical Methods In Cardiovascular Physiology
Author: Liang Zhong,Ru San Tan,Eddie Yin-kwee Ng,Dhanjoo N Ghista
Publsiher: World Scientific
Total Pages: 460
Release: 2019-04-26
ISBN: 9813270659
Category: Medical
Language: EN, FR, DE, ES & NL

Computational And Mathematical Methods In Cardiovascular Physiology Book Excerpt:

Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.

Biomechanical Characterization of Atherosclerotic Plaques

Biomechanical Characterization of Atherosclerotic Plaques
Author: Donna Michelle Ebenstein
Publsiher: Unknown
Total Pages: 810
Release: 2002
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Biomechanical Characterization of Atherosclerotic Plaques Book Excerpt: