Description : This book gathers current research from across the globe in the study of cancer in the elderly. Topics discussed include cancer-related fatigue in elderly patients; rectal cancer staging; hormone therapy treatment in elderly patients with hormone-sensitive breast cancer; age and gender-related risk for oral cancer; cancer treatment for patients with Alzheimer's disease and oesophageal cancer in the elderly.
Description : Hardbound. This scientific update has been produced as a result of a meeting held in Paris in January 1997, under the auspices of EONS (European Oncology Nursing Society) and ESO (European School of Oncology), where experts from medical and nursing fields gave presentations and discussed the problems relating to cancer in the elderly.Cancer is predominantly a disease of old age and the incidence of cancer is, therefore, greater in the older section of the population. Yet our knowledge of elderly-specific treatment regimens and nursing interventions is poor. Epidemiological studies show that the number of elderly people, and thus the number of cases of cancer, will increase dramatically over the next 25 years.This update seeks to examine current knowledge and practice of cancer care for the elderly, to highlight inadequacies and to point to ways in which practice may be improved and future research contribute to our understanding of cancer in the eld
Description : This book presents comprehensive assessment and up-to-date discussion of the epidemiology, prevention, and treatment of cancer in the elderly, highlighting the growing demands of the disease, its biology, individual susceptibility, the impact of state-of-the-art and emerging therapies on reducing morbidity, and decision making processes. Describes pivotal results from clinical trials on the management of site-specific cancers, such as breast, gastrointestinal, gynecologic, and hematalogic malignancies! Collecting contributions from more than 40 expert clinicians and researchers and citing more than 2300 references, Cancer in the Elderly highlights dilemmas, controversies, and the changing paradigms of cancer in the elderly studies the molecular biology of cancer and its relationship to the aging process addresses inherited genetic predisposition to cancer reviews opportunities for cancer prevention in the elderly examines the role of diet, exercise, alcohol, and tobacco in cancer promotion, causation, and progression details cancer prevention and treatment in elderly patients with comorbid conditions and more! Featuring up-to-the-minute thought and spotlighting recent advances in research, Cancer in the Elderly is an outstanding guide for medical, surgical, and radiation oncologists; geriatricians; psychologists; internists and family practitioners; gynecologists; oncology nurses; public health professionals; health policy specialists; health economists; health educators; prevention and early detection advocates; epidemiologists; biometricians; statisticians; and medical school and graduate students in these disciplines.
Description : As the population ages, clinicians are facing an increasing number of elderly patients with colorectal cancer. These patients pose unique challenges as they have more comorbidities and lower functional reserves. In addition, the treatment goals may differ from those in younger patients. This book discusses in depth the different aspects of management of colorectal cancer in the elderly. After the provision of pertinent background information on the normal physiology of aging, screening and diagnosis are discussed. Subsequent chapters focus on a range of issues associated with the surgical and perioperative care of these patients and with adjuvant treatment and palliative care. Each chapter provides helpful take-home messages in bullet point form, and numerous informative figures and tables are also included. The authors are surgeons, physicians, anesthetists, geriatricians, oncologists, and allied health professionals with extensive experience in the field.
Description : Management of Cancer in the Older Patient, by Drs. Arash Naeim, David Reuben, and Patricia Ganz, offers the help you need to effectively diagnose, refer, and manage cancer in geriatric patients. You’ll see how to provide effective cancer screening; refer your patients to the right oncologist; deal with comorbidities, frailties, and other complications; navigate end-of-life issues; and much more. A templated, user-friendly format makes it easy to find and apply the answers you need. See how to best manage geriatric cancer patients with help from leading specialists in both geriatrics and oncology Make informed decisions as to when to refer patients to specialists. Provide the supportive care your patients and their families need on issues such as such as mental health, pain, fatigue, nausea, insomnia. Be prepared to help cancer survivors navigate their after-treatment care including adjuvant therapy, side effects, second cancers, quality of life, and other concerns. Offer accurate guidance on ethical issues like competency, end of life, hospice, the role of the caregiver, and more.
Description : I was looking at Mrs T – all 45 kilos of her – with somewhat puzzled thoughts. I had prescribed her capecitabine at very prudent doses, in view of her 91-year-old kidneys and physiology. She had reduced my treatment even further, “because it was making her tired.” As a result, she was taking a grand total of 500 mg of capecitabine a day. Yet, her metastatic, ER/PR-negative, Her2-positive breast cancer was undoubtedly responding. Her pain was improving and her chest mass was shrinking, as were her lung metastases... What was the secret of that response? Were Mrs T’s kidneys eli- nating even less drug than predicted by her creatinine clearance? Was her sarcopenia altering drug distribution? Was she absorbing more drug than average? Or was her tumor exquisitely sensitive to fluoropyrimidines? “Physicians,” said Voltaire, “pour drugs they know little for diseases they know even less into patients they know no- ing about.” Medicine has made tremendous progress since the eighteenth century. Yet, there are fields where quite a lot remains to be learned. In developed countries, 25% of breast cancers occur in patients aged 75 years and older. Yet, these patients represent only 4% of the population of traditional clinical trials. That ought to let us wonder how relevant data acquired in patients in their 60s are to a nonagenarian. Fortunately, geriatric oncologists have been stepping up to the task and have gen- ated data to help us to treat such patients.
Description : This thesis studies quality of care for patients diagnosed with pancreatic (or periampullary) carcinoma in the Netherlands, using nationwide data in the Netherlands Cancer Registry. Adherence to the national guideline recommendations on surgical and chemotherapeutical treatments are studied, as well as aspects of organisation of care (e.g. multidisciplinary discussion). The centralisation process of pancreatic surgery for cancer is studied at a regional and a national level, following mutual agreements (bottom-up) and a volume standard (top-down), respectively. Furthermore, the well-established volume-outcome relationship after pancreatic resection was also studied at time of surgical exploration with curative intent and after surgery without resection of the primary tumour. In this era of an aging population, an increasing number of elderly persons is diagnosed with pancreatic cancer. Unfortunately, elderly patients are underrepresented in studies on which the evidence in guidelines is based. Objective information is needed about their short- and long-term benefits and risks compared to younger patients. In this thesis, multiple elderly age groups were distinguished above 70 years of age and nationwide trends in surgical and systemic treatment are described, as well as short-term mortality and long-term survival after treatment.
Description : This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older gynecological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.