Capillary Electrophoresis Methods for Pharmaceutical Analysis

Capillary Electrophoresis Methods for Pharmaceutical Analysis
Author: Satinder Ahuja,Mohamedilias Jimidar
Publsiher: Elsevier
Total Pages: 546
Release: 2011-08-09
ISBN: 0080559611
Category: Medical
Language: EN, FR, DE, ES & NL

Capillary Electrophoresis Methods for Pharmaceutical Analysis Book Excerpt:

Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control. - Provides current status and future developments in CE analysis of pharmaceuticals. - Explains how to develop and validate methods. - Includes major pharmaceutical applications including assays and impurity testing.

Capillary Electrophoresis Methods For Pharmaceutical Analysis

Capillary Electrophoresis Methods For Pharmaceutical Analysis
Author: Ahuja
Publsiher: Unknown
Total Pages: 529
Release: 2009-01-01
ISBN: 9788131219416
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Capillary Electrophoresis Methods For Pharmaceutical Analysis Book Excerpt:

Capillary Electrophoresis Methods for Pharmaceutical Analysis

Capillary Electrophoresis Methods for Pharmaceutical Analysis
Author: George Lunn
Publsiher: Wiley-Interscience
Total Pages: 1544
Release: 2000-02-21
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Capillary Electrophoresis Methods for Pharmaceutical Analysis Book Excerpt:

Capillary Electrophoresis Techniques for Pharmaceutical Analysis at your fingertips-A complete, up-to-date library. This invaluable database--also available on CD-ROM--gives you fast, easy access to the growing literature on capillary electrophoresis (CE). Nearly 3,000 abstracts from approximately 900 publications make up this comprehensive library, listing CE techniques for the analysis of more than 700 active pharmaceutical compounds. From acarbose to mephobarbital to zopiclone--a number of procedures are grouped together for each compound. Detailed, precise information lets you replicate methods without referring to original articles as well as customize methods for specific needs. Features include: * Methods for drugs in biological fluids such as blood or urine as well as for bulk and formulated drugs * Name and structure of each target compound as well as molecular weight and formula, CAS registry numbers, and Merck index number * Experimental conditions for each method, including sample preparation, analytical matrix, capillary/capillary instrument model, capillary temperature, interfering compounds, and more * Bibliography of reviews of capillary electrophoresis procedures The CD-ROM additionally combines the four-volume HPLC Methods for Pharmaceutical Analysis with thousands of methods listed for more than 1,300 compounds. This immensely useful reference will save you countless hours of online and library research.

Pharmaceutical and Biomedical Applications of Capillary Electrophoresis

Pharmaceutical and Biomedical Applications of Capillary Electrophoresis
Author: S.M. Lunte,D.M. Radzik
Publsiher: Elsevier
Total Pages: 508
Release: 1996-08-13
ISBN: 9780080538716
Category: Science
Language: EN, FR, DE, ES & NL

Pharmaceutical and Biomedical Applications of Capillary Electrophoresis Book Excerpt:

The book describes the theory and applications of Capillary Electrophoresis (CE) in the field of pharmaceutical and biomedical analysis. It is targeted towards users who are intimately involved in analytical problems, especially those which involve small samples. This book presents the technique of capillary electrophoresis from the point of view of the serious hands-on use in the field of pharmaceutical and biomedical analysis. An overview of general theory is presented to acquaint the novice with the fundamental principles. A more theoretical approach is taken in the presentation of electrokinetic chromatography. The next chapter discusses advances in column technologies, the preceding chapters having provided a foundation as to how separations occur. In the next three chapters, recognized experts in their fields present fundamentals and state-of-the-art techniques in the areas of optical, electrochemical and mass spectrometric detection. The major focus of the remaining chapters is on applications. This includes the analysis of pharmaceuticals, amino acids and peptides, macromolecules, nucleosides, nucleotides and oligonucleotides. The use of CE for analysis of small ions and separation of biological particles is also discussed. The issue of sample preparation for analysis by CE is addressed, especially as it relates to clinical analysis.

Analysis of Pharmaceuticals by Capillary Electrophoresis

Analysis of Pharmaceuticals by Capillary Electrophoresis
Author: Kevin D. Altria
Publsiher: Springer Science & Business Media
Total Pages: 285
Release: 2013-04-17
ISBN: 3322850110
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Analysis of Pharmaceuticals by Capillary Electrophoresis Book Excerpt:

Dieser erste Titel einer ganzen Serie von anwendungsbezogenen Handbüchern zur Kapillarelektrophorese beschäftigt sich mit der Analytik von pharmazeutischen Substanzen. Dabei werden verschiedene Techniken praxisnah erläutert. Jeder, der im Labor - ob wissenschaftlich oder praxisnah - mit der Analyse von oft chiralen Pharmazeutika konfrontiert ist, wird viele Hinweise und Tips für seine Arbeit finden.USP: Einzige Monographie zur Analyse von Pharmazeutika mit CE This book describes the current state of the art for the analysis of pharmaceuticals by capillary electrophoresis and contains several hundred references to specific applications and methods. The main purpose of the book is to present the application possibilities of CE an therefore tabulated application data are provided. Chapters of the book are devoted to providing details of individual application areas such as chiral analysis, determination of drug related impurities, determination of drug counter-ions, drug residue monitoring and main component assay. An introductory chapter provides theoretical background to CE an related techniques. A chapter is dedicated to capillary electrochromatography which highlights the importance this technique currently possesses. Successful regulatory acceptance of CE methods is also described. A comprehensive chapter covers method validation aspects. Other chapters include discrete areas such as the use of non-aqueous solvents, forensic applications of CE, the application of experimental designs, determination of drugs in biofluids, and the analysis of vitamins by CE.

Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques Third Edition

Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques  Third Edition
Author: James P. Landers
Publsiher: CRC Press
Total Pages: 1592
Release: 2007-12-18
ISBN: 9781420004953
Category: Medical
Language: EN, FR, DE, ES & NL

Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques Third Edition Book Excerpt:

Although capillary electrophoresis (CE) technology has evolved quickly from the research laboratory into practical application in numerous fields, many scientists still debate its merits. While the body of international CE literature continues to expand dramatically, experts still question whether it has provided the speed, resolving power, peak capacity, sensitivity, robustness, and cost-reduction promised by its pioneers. Responding to these criticisms, this third edition brings together cutting-edge researchers to demonstrate the utility of CE across a broad spectrum of disciplines including— Forensic science Medical diagnostics Pharmaceutical science Genetic analysis Biotechnology Fluid mechanics Environmental science Biomedical research Nanotechnology Proteomics Detailed Analysis of New Methodologies and Applications Eagerly awaited by researchers and technicians who transformed the first two editions into bestsellers, this latest volume once again delivers. Emphasizing microseparations and microfluidics, the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. Aided by contributions from leading international experts, this text remains a seminal reference for numerous chemistry, biology, and engineering fields.

Encyclopedia of Analytical Science

Encyclopedia of Analytical Science
Author: Anonim
Publsiher: Elsevier
Total Pages: 5109
Release: 2019-04-02
ISBN: 008101984X
Category: Science
Language: EN, FR, DE, ES & NL

Encyclopedia of Analytical Science Book Excerpt:

The third edition of the Encyclopedia of Analytical Science is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.g., forensic, environmental and clinical); and analytes (e.g., arsenic, nucleic acids and polycyclic aromatic hydrocarbons), providing a one-stop resource for analytical scientists. Offers readers a one-stop resource with access to information across the entire scope of modern analytical science Presents articles split into three broad areas: analytical techniques, areas of application and and analytes, creating an ideal resource for students, researchers and professionals Provides concise and accessible information that is ideal for non-specialists and readers from undergraduate levels and higher

Development of Capillary Electrophoresis Methods Coupled to Mass Spectrometry for Biomedical and Pharmaceutical Analysis

Development of Capillary Electrophoresis Methods Coupled to Mass Spectrometry for Biomedical and Pharmaceutical Analysis
Author: Anisa Elhamili
Publsiher: Unknown
Total Pages: 64
Release: 2011
ISBN: 9789155479961
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Development of Capillary Electrophoresis Methods Coupled to Mass Spectrometry for Biomedical and Pharmaceutical Analysis Book Excerpt:

Capillary Electromigration Separation Methods

Capillary Electromigration Separation Methods
Author: Colin F. Poole
Publsiher: Elsevier
Total Pages: 626
Release: 2018-04-13
ISBN: 0128096144
Category: Science
Language: EN, FR, DE, ES & NL

Capillary Electromigration Separation Methods Book Excerpt:

Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins. Edited and authored by world-leading capillary electrophoresis experts Presents comprehensive coverage on the subject Includes extensive referencing that facilitates the identification of key research developments Provides more than 50 figures and tables that aid in the retention of key concepts

Pharmaceutical Analysis E Book

Pharmaceutical Analysis E Book
Author: David G. Watson
Publsiher: Elsevier Health Sciences
Total Pages: 480
Release: 2020-06-10
ISBN: 0702078093
Category: Medical
Language: EN, FR, DE, ES & NL

Pharmaceutical Analysis E Book Book Excerpt:

Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised and well established textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Worked calculation examples and self-assessment test questions aid continuous learning reinforcement throughout Frequent use of figures and diagrams clarify points made in the text Practical examples are used to show the application of techniques Key points boxes summarise the need to know information for each topic Focuses on the most relevant and frequently used techniques within the field

HPLC Methods for Pharmaceutical Analysis

HPLC Methods for Pharmaceutical Analysis
Author: George Lunn
Publsiher: Wiley-Interscience
Total Pages: 7009
Release: 2000-06-06
ISBN: 9780471332978
Category: Science
Language: EN, FR, DE, ES & NL

HPLC Methods for Pharmaceutical Analysis Book Excerpt:

HPLC and CE Methods for Pharmaceutical Analysis The complete, up-to-date library at the click of a mouse This invaluable database gives you fast, easy access to more than 13,000 abstracts from the current literature on HPLC and capillary electrophoresis (CE). Incorporating the four-volume HPLC Methods for Pharmaceutical Analysis plus the newly introduced Capillary Electrophoresis for Pharmaceutical Analysis, this CD-ROM features an extensive library of methods used in the analysis of most pharmaceutical compounds. It lists available HPLC techniques for more than 1,300 compounds and CE methods for more than 700 compounds, with a number of techniques described for each compound. Detailed, precise information lets you replicate methods without having to refer to the original publications as well as customize methods for very specific needs. You can instantly locate basic compound information--molecular weight and formula, CAS number, and Merck index number--plus experimental conditions for each method. Complex and substructure searching capabilities let you search the entire database by compound, matrix, HPLC variables, and author--saving you countless hours of online or library research. Minimum system requirements: * IBM-compatible PC 486 * Win95 or higher * CD-ROM drive * 8MB RAM * XXXMB free hard disk space Visit us on the Internet: www.wiley.com

Capillary Electrophoresis

Capillary Electrophoresis
Author: Philippe Schmitt-Kopplin
Publsiher: Springer Science & Business Media
Total Pages: 814
Release: 2008-02-25
ISBN: 1588295397
Category: Science
Language: EN, FR, DE, ES & NL

Capillary Electrophoresis Book Excerpt:

This book presents a selection of current capillary electrophoresis methods used to separate representative types of molecules and particles and in combination with different detection techniques. It includes practical details which are hard to find elsewhere. The volume is intended for beginners in the field and provides an overview of the technique and a starting point for the exploration of the defined literature on different application topics.

Chemometric Methods in Capillary Electrophoresis

Chemometric Methods in Capillary Electrophoresis
Author: Grady Hanrahan,Frank A. Gomez
Publsiher: John Wiley & Sons
Total Pages: 336
Release: 2009-10-22
ISBN: 9780470530184
Category: Science
Language: EN, FR, DE, ES & NL

Chemometric Methods in Capillary Electrophoresis Book Excerpt:

Use chemometric techniques to develop optimum separation conditions for capillary electrophoreses For all its advantages, capillary electrophoresis (CE) also carries significant disadvantages for the researcher. Offering a unique blend of information from authors active in a variety of developments of chemometrics in CE, Chemometric Methods in Capillary Electrophoresis presents modern chemometric methods as an alternative to help alleviate the problems commonly encountered during routine analysis and method development. Focusing on current chemometric methods utilized in CE endeavours by research-active experts in the field, the book begins with a thorough introduction to CE and chemometric-related concepts and the need for modern chemometric methods in CE. Part 1 discusses differing types of screening designs and response surface methodology¿in an¿application based format Part 2 includes vital discussion on various exploratory data analysis, prediction, and classification techniques utilized in CE-related studies Part 3 provides practical information on modelling quantitative structure relationships Part 4 explores transformation techniques, in particular fundamental studies and applications of cross-correlation and Hadamard Transform Electrophoresis Showing how chemometric methods are applied in a wide array of applications including biological, medical, pharmaceutical, food, forensic, and environmental science, Chemometric Methods in Capillary Electrophoresis is not only highly significant to capillary electrophoresis-based endeavours, but instructive for investigators active in other areas of separation science who could benefit from its informative content.

Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis

Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis
Author: Peter Mikuš
Publsiher: BoD – Books on Demand
Total Pages: 210
Release: 2012-08-29
ISBN: 9535106570
Category: Medical
Language: EN, FR, DE, ES & NL

Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis Book Excerpt:

The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques.

Capillary Electrophoresis of Proteins and Peptides

Capillary Electrophoresis of Proteins and Peptides
Author: Mark A. Strege,Avinash L. Lagu
Publsiher: Springer Science & Business Media
Total Pages: 332
Release: 2008-02-04
ISBN: 159259798X
Category: Science
Language: EN, FR, DE, ES & NL

Capillary Electrophoresis of Proteins and Peptides Book Excerpt:

Throughout the more than 20 years that have followed the beginnings of capillary electrophoresis (CE), its application to the analysis of proteins and peptides has continued to be reliable, versatile, and productive. Over time, CE has matured to become a superb complement to HLPC, and in many cases has also evolved as an automated and quantitative replacement for conventional slab gel electrophoresis methods such as SDS-PAGE and isoelectric focusing. Within Capillary Electrophoresis of Proteins and Peptides, we have assembled contributions from researchers who are applying state-of-the-art CE for protein and peptide analysis, including topics that we believe are of great potential both in the present and for the future. In comparison to traditional separation methods, CE represents a miniaturized analysis technique (especially in its microchip-based format) that is highly dependent upon the basic fundamentals of effective sample recovery and high sensitivity detection. With these issues in mind, Chapters 1–4 describe recently developed approaches for both capillary coatings and analyte detection via laser-induced fluorescence. Since the discipline of biotechnology has established itself as a primary platform for the application of CE to the analysis of proteins and peptides, Chapters 5–7 demonstrate a variety of examples of the specific techniques that have been applied for the development of biopharmaceuticals and their commercialization. The methods covered here include also the analysis of oligosaccharides from glycoproteins.

Bioanalytics

Bioanalytics
Author: Friedrich Lottspeich,Joachim Engels
Publsiher: John Wiley & Sons
Total Pages: 1134
Release: 2018-03-26
ISBN: 3527339191
Category: Science
Language: EN, FR, DE, ES & NL

Bioanalytics Book Excerpt:

Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a birdï¿1⁄2s eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology

Employing Capillary Electrophoresis as a Separation Method for Pharmaceutical Analysis

Employing Capillary Electrophoresis as a Separation Method for Pharmaceutical Analysis
Author: Laura L. Lessard
Publsiher: Unknown
Total Pages: 116
Release: 2004
ISBN: 1928374650XXX
Category: Capillary electrophoresis
Language: EN, FR, DE, ES & NL

Employing Capillary Electrophoresis as a Separation Method for Pharmaceutical Analysis Book Excerpt:

Capillary electrophoresis as a technique has many applications in a broad range of fields including forensics, environmental analysis, and biological analysis and as a separation method for samples such as oligonucleotides, peptides, proteins, and pharmaceuticals. The research conducted herein is for the antibiotic pharmaceutical ciprofloxacin HCl and three impurities. Sample stacking was used to overcome the poor limits of detection generally associated with CE, which successfully improved the limits of detection when compared to results from a previous feasibility study. This thesis encompasses three stages: method development, limit of detection determination, and proof of successful method development by analysis of tablets of ciprofloxacin. The method developed is reproducible, yields high resolution, and provides intense signals with respect to the detection generally achievable with capillary electrophoresis. The limits of detection of the impurities were determined to be below 0.05% (by concentration) of that of the active ingredient, and a brief tablet analysis showed that formulated tablets could be analyzed with this method.

Capillary Gel Electrophoresis

Capillary Gel Electrophoresis
Author: Andras Guttman,László Hajba
Publsiher: Newnes
Total Pages: 390
Release: 2021-12-04
ISBN: 0080931359
Category: Science
Language: EN, FR, DE, ES & NL

Capillary Gel Electrophoresis Book Excerpt:

Capillary Gel Electrophoresis and Related Microseparation Techniques covers all theoretical and practical aspects of capillary gel electrophoresis. It also provides an excellent overview of the key application areas of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods. It not only gives readers a better understanding of how to utilize this technology, but also provides insights into how to determine which method will provide the best technical solutions to particular problems. This book can also serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses. Covers all theoretical and practical aspects of capillary gel electrophoresis Excellent overview of the key applications of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods Teaches readers how to use the technology and select methods that are ideal for fundamental problems Can serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses

HPLC Methods for Pharmaceutical Analysis

HPLC Methods for Pharmaceutical Analysis
Author: George Lunn
Publsiher: Wiley-Interscience
Total Pages: 7009
Release: 2000-01-21
ISBN: 9780471331926
Category: Science
Language: EN, FR, DE, ES & NL

HPLC Methods for Pharmaceutical Analysis Book Excerpt:

HPLC and CE Methods for Pharmaceutical Analysis The complete, up-to-date library at the click of a mouse This invaluable database gives you fast, easy access to more than 13,000 abstracts from the current literature on HPLC and capillary electrophoresis (CE). Incorporating the four-volume HPLC Methods for Pharmaceutical Analysis plus the newly introduced Capillary Electrophoresis for Pharmaceutical Analysis, this CD-ROM features an extensive library of methods used in the analysis of most pharmaceutical compounds. It lists available HPLC techniques for more than 1,300 compounds and CE methods for more than 700 compounds, with a number of techniques described for each compound. Detailed, precise information lets you replicate methods without having to refer to the original publications as well as customize methods for very specific needs. You can instantly locate basic compound information--molecular weight and formula, CAS number, and Merck index number--plus experimental conditions for each method. Complex and substructure searching capabilities let you search the entire database by compound, matrix, HPLC variables, and author--saving you countless hours of online or library research. Minimum system requirements: * IBM-compatible PC 486 * Win95 or higher * CD-ROM drive * 8MB RAM * XXXMB free hard disk space Visit us on the Internet: www.wiley.com

Capillary Electrophoresis

Capillary Electrophoresis
Author: Suvardhan Kanchi,Salvador Sagrado,Myalo I. Sabela,Krishna Bisetty
Publsiher: CRC Press
Total Pages: 396
Release: 2017-08-21
ISBN: 1351846736
Category: Medical
Language: EN, FR, DE, ES & NL

Capillary Electrophoresis Book Excerpt:

Capillary electrophoresis (CE) has become an established method with widespread recognition as an analytical technique of choice in numerous analytical laboratories, including industrial and academic sectors. Pharmaceutical and biochemical research and quality control are the most important CE applications. This book provides a comparative assessment of related techniques on mode selection, method development, detection, and quantitative analysis and estimation of pharmacokinetic parameters and broadens the understanding of modern CE applications, developments, and prospects. It introduces the fundamentals of CE and clearly outlines the procedures used to mitigate several barriers, such as detection limits, signal detection, changing capillary environment, resolution separation of analytes, and hyphenation of mass spectrometry with CE, for a range of analytical problems. Each chapter outlines a specific electrophoretic variant with detailed instructions and some standard operating procedures. In this respect, the book meets its desired goal of rendering assistance to lovers of electrophoresis.