Cell and Tissue Based Molecular Pathology E Book

Cell and Tissue Based Molecular Pathology E Book
Author: Raymond R. Tubbs,Mark H. Stoler
Publsiher: Elsevier Health Sciences
Total Pages: 452
Release: 2008-09-22
ISBN: 1437719481
Category: Medical
Language: EN, FR, DE, ES & NL

Cell and Tissue Based Molecular Pathology E Book Book Excerpt:

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

Cell and Tissue Based Molecular Pathology A Volume in the Series Foundations in Diagnostic Pathology

Cell and Tissue Based Molecular Pathology  A Volume in the Series Foundations in Diagnostic Pathology
Author: Alexander J. F. Lazar
Publsiher: Unknown
Total Pages: 135
Release: 2009
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Cell and Tissue Based Molecular Pathology A Volume in the Series Foundations in Diagnostic Pathology Book Excerpt:

Diagnostic Molecular Pathology Cell and tissue genotyping

Diagnostic Molecular Pathology  Cell and tissue genotyping
Author: C. S. Herrington,James O'Donnell McGee
Publsiher: Unknown
Total Pages: 135
Release: 1992
ISBN: 1928374650XXX
Category: Molecular biology
Language: EN, FR, DE, ES & NL

Diagnostic Molecular Pathology Cell and tissue genotyping Book Excerpt:

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
Author: C. S. Herrington,James O'Donnell McGee
Publsiher: Unknown
Total Pages: 218
Release: 1992
ISBN: 9780199632411
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Diagnostic Molecular Pathology Book Excerpt:

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 634
Release: 2019-11-23
ISBN: 0128132582
Category: Medical
Language: EN, FR, DE, ES & NL

Essential Concepts in Molecular Pathology Book Excerpt:

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Molecular Pathology

Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 802
Release: 2017-11-09
ISBN: 0128027878
Category: Medical
Language: EN, FR, DE, ES & NL

Molecular Pathology Book Excerpt:

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 582
Release: 2016-10-05
ISBN: 0128011572
Category: Science
Language: EN, FR, DE, ES & NL

Diagnostic Molecular Pathology Book Excerpt:

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Basic Concepts of Molecular Pathology

Basic Concepts of Molecular Pathology
Author: Philip T. Cagle,Timothy Craig Allen
Publsiher: Springer Science & Business Media
Total Pages: 190
Release: 2009-06-10
ISBN: 9780387896267
Category: Medical
Language: EN, FR, DE, ES & NL

Basic Concepts of Molecular Pathology Book Excerpt:

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Molecular Pathology of Liver Diseases

Molecular Pathology of Liver Diseases
Author: Satdarshan P. S. Monga
Publsiher: Springer Science & Business Media
Total Pages: 931
Release: 2010-12-14
ISBN: 9781441971074
Category: Medical
Language: EN, FR, DE, ES & NL

Molecular Pathology of Liver Diseases Book Excerpt:

Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Molecular Pathology

Molecular Pathology
Author: John M. S. Bartlett,Abeer Shaaban,Fernando Schmitt
Publsiher: Cambridge University Press
Total Pages: 400
Release: 2016-03-01
ISBN: 1107443466
Category: Medical
Language: EN, FR, DE, ES & NL

Molecular Pathology Book Excerpt:

Practical overview of current molecular techniques and their applications in each organ system, for practising and trainee pathologists.

Molecular Pathology

Molecular Pathology
Author: Antoni Horst
Publsiher: CRC Press
Total Pages: 474
Release: 2018-05-04
ISBN: 1351083228
Category: Science
Language: EN, FR, DE, ES & NL

Molecular Pathology Book Excerpt:

This book provides modern views of developments in medical sciences based on advances in molecular pathology. Topics discussed include the molecule; the genome of eukaryotes and its function; gene regulation; the proteins; molecular aspects of inflammation, immunology, and carcinogenesis; molecular biology of the nervous system; molecular defects in the endocrine system; molecular diseases of the blood and blood-forming tissues; and diagnosis of molecular diseases. Four tables and 75 figures illustrate the concepts and provide a quick means to reference important data. Immunologists, pathologists, geneticists, and all other researchers in the biological and medical sciences will find a wealth of information in this ground-breaking new book.

Diagnostic Pathology Molecular Oncology E Book

Diagnostic Pathology  Molecular Oncology E Book
Author: Mohammad A Vasef,Aaron Auerbach
Publsiher: Elsevier Health Sciences
Total Pages: 1000
Release: 2019-08-08
ISBN: 0323611451
Category: Medical
Language: EN, FR, DE, ES & NL

Diagnostic Pathology Molecular Oncology E Book Book Excerpt:

Covering all aspects of molecular pathology as it relates to the transformation and pathogenesis of cancer, this award-winning volume in the Diagnostic Pathology series is an expert resource for pathologists at all levels of experience and training, both as a quick reference and as an efficient review to improve knowledge and skills. This easily accessible, point-of-care reference features templated, bulleted content that is generously illustrated with charts, graphs, tables, and color photomicrographs of histology with special stains. It offers a practical, clinical approach to examining how molecular mutations affect common medical diseases and identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Provides updated information on molecular mutations in different tumors, including solid tumors and hematopoietic neoplasms, and new targeted therapies geared toward these molecular alterations Discusses now widely used immunotherapy treatments, including how immunotherapy has revolutionized the treatment of many neoplasms such as breast and lung carcinomas and lymphoma Features more than 2,000 annotated images throughout, including H&E stains, immunostains, and FISH images Covers timely topics such as: Recent advances in cancer immunotherapy, specifically in the molecular basis of immunotherapy Newly discovered targeted therapies, including multiple lung carcinoma therapies now considered for patients based on existing mutations to specific genes (KRAS, ALK, BRAF, and ROS) The need for integration of myeloid and lymphoid gene panels due to increased knowledge from next generation sequencing studies of new mutations and the resulting newly developed molecular targets Increased usage of next generation sequencing techniques Changes to hematopoietic tumor details based on revised WHO guidelines Recipient of a 2016 BMA Award: Highly Commended, Pathology (previous edition)

Molecular Surgical Pathology

Molecular Surgical Pathology
Author: Liang Cheng,John N. Eble
Publsiher: Springer Science & Business Media
Total Pages: 436
Release: 2012-11-15
ISBN: 1461449006
Category: Medical
Language: EN, FR, DE, ES & NL

Molecular Surgical Pathology Book Excerpt:

Molecular Surgical Pathology provides a concise review of recent advancement of molecular pathology in each organ system. The text is intended as a “first knowledge base” in the rapidly evolving field of molecular pathology and is organized in a user friendly outline format. Each chapter is organ-based and covers important aspects of molecular pathology and its impact on our daily practice of surgical pathology. The topics presented herein constitute the fundamentals and core base of knowledge required for the daily practice of surgical pathology. This book focuses on the practical utilities of molecular techniques and molecular biomarkers in daily practice of surgical pathology. The emphasis is on the impact of molecular pathology for tumor classification, diagnosis and differential diagnosis as well as its implications for patient management and personalized care. Numerous tables, diagrams and color illustrations are included throughout. Molecular Surgical Pathology will prove a very useful resource for pathologists in training who are preparing for the Board and in-service examination. It will also be a unique and invaluable resource for medical oncologists, physicians, other medical professionals and basic research scientists with interest in molecular pathology of human cancers.

Diagnostic Molecular Pathology in Practice

Diagnostic Molecular Pathology in Practice
Author: Iris Schrijver
Publsiher: Springer Science & Business Media
Total Pages: 339
Release: 2011-09-09
ISBN: 9783642196775
Category: Medical
Language: EN, FR, DE, ES & NL

Diagnostic Molecular Pathology in Practice Book Excerpt:

This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.

Practical Oncologic Molecular Pathology

Practical Oncologic Molecular Pathology
Author: Yi Ding,Linsheng Zhang
Publsiher: Springer Nature
Total Pages: 449
Release: 2021-07-10
ISBN: 3030732274
Category: Medical
Language: EN, FR, DE, ES & NL

Practical Oncologic Molecular Pathology Book Excerpt:

This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Rosai and Ackerman s Surgical Pathology E Book

Rosai and Ackerman s Surgical Pathology E Book
Author: Juan Rosai
Publsiher: Elsevier Health Sciences
Total Pages: 2892
Release: 2011-06-20
ISBN: 032308804X
Category: Medical
Language: EN, FR, DE, ES & NL

Rosai and Ackerman s Surgical Pathology E Book Book Excerpt:

Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.

Connective Tissue Disease

Connective Tissue Disease
Author: Jouni Uitto
Publsiher: CRC Press
Total Pages: 568
Release: 2021-07-29
ISBN: 1000447227
Category: Science
Language: EN, FR, DE, ES & NL

Connective Tissue Disease Book Excerpt:

This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.

Bladder Pathology

Bladder Pathology
Author: Liang Cheng,Antonio Lopez-Beltran,David G Bostwick
Publsiher: John Wiley & Sons
Total Pages: 768
Release: 2012-05-18
ISBN: 111827539X
Category: Medical
Language: EN, FR, DE, ES & NL

Bladder Pathology Book Excerpt:

The human urinary bladder is subject to a unique andextraordinarily diverse array of congenital, inflammatory,metaplastic, and neoplastic abnormalities. This book providescontemporary, comprehensive, and evidence-based practiceinformation for pathologists, urologists, oncologists, and othermedical professionals. In Bladder Pathology, a full spectrum of pathologicconditions that afflict the bladder and urothelium are describedand lavishly illustrated. With its emphasis on diagnostic criteriaand differential diagnoses, this book is of particular value topracticing pathologists—assisting in the pathologist’srecognition, understanding, and accurate interpretation of thelight microscopic findings in bladder specimens. Features and benefits of this new volume include: • 1,741 high-quality, color illustrations and 112 tables toillustrate the wide range of pathologic and clinical features inthe urinary tract • An evidence-based approach to diagnosis and patientmanagement for infectious, nonneoplastic, and neoplastic conditions • Recent advances in the molecular genetics of the urinarybladder with discussion of their current or potential impact on diagnosis and personalized patient care • With emphasis on the scientific validation of currentdiagnostic methods and their direct application in clinicalpractice, Bladder Pathology is a cutting-edge resource thatnot only offers comprehensive research and clinicalinformation for practicing surgical pathologists, urologists,oncologists, and their clinical colleagues, but also captures agenuine sense of excitement about recent advances in this vital,ever-evolving field.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
Author: Debra G.B. Leonard
Publsiher: Springer
Total Pages: 1001
Release: 2016-02-02
ISBN: 331919674X
Category: Medical
Language: EN, FR, DE, ES & NL

Molecular Pathology in Clinical Practice Book Excerpt:

This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.

Molecular Pathology and Diagnostics of Cancer

Molecular Pathology and Diagnostics of Cancer
Author: Domenico Coppola
Publsiher: Springer Science & Business Media
Total Pages: 601
Release: 2013-11-29
ISBN: 9400771924
Category: Medical
Language: EN, FR, DE, ES & NL

Molecular Pathology and Diagnostics of Cancer Book Excerpt:

Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered. Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.