Standardisation In Cell And Tissue Engineering

Author by : V Salih
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 57
Total Download : 417
File Size : 49,7 Mb
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Description : The increased use of biodegradable synthetic or natural scaffolds combined with cells and/or biological molecules, in order to create functional replacement tissue in a damaged tissue site, has led to the need for the development of ‘best practice’ methods in the area of tissue engineering to help ensure the creation of safe, high quality products. Standardisation in cell and tissue engineering introduces concepts and current practice in the field of cell and tissue engineering to a wide audience and aims to provide awareness of the importance of standardisation in this area while suggesting directions for further investigation. Part one provides an overview of methods for cell and tissue engineering and includes chapters on the fundamentals of cell and matrix biology for tissue engineering, 3D collagen biomatrix development, and control and vascularisation of tissue-engineered constructs. Part two begins with a chapter exploring the methods and protocols of standardisation in cell and tissue engineering before moving on to highlight issues of quality control in cell and tissue engineering, standardised chemical analysis and testing of biomaterials and principles of good laboratory practice (GLP) for in vitro cell culture applications. Standardisation in cell and tissue engineering is a standard reference for leading research groups, government agencies, regulatory bodies, and researchers and technicians at all levels across the whole range of disciplines using cell culture within the pharmaceutical, biotechnology and biomedical industries. Introduces concepts and current practice in the field of cell and tissue engineering Highlights the importance of standardisation in cell and tissue engineering and suggests directions for further investigation Explores methods and protocols of standardisation in cell and tissue engineering and issues of quality control in cell and tissue engineering


Stem Cell And Tissue Engineering

Author by : Song Li
Languange : en
Publisher by : World Scientific
Format Available : PDF, ePub, Mobi
Total Read : 75
Total Download : 197
File Size : 41,6 Mb
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Description : Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.


Stem Cell Biology And Tissue Engineering In Dental Sciences

Author by : Paul Sharpe
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 61
Total Download : 426
File Size : 52,5 Mb
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Description : The editors have compiled basic embryology and developmental biology with keen focus on stem cells, basic cell and matrix biology with relevance to tissue regeneration and repair, biomaterials (including nanotechnology) and current applications in various disciplines of dental science.


Fundamentals Of Tissue Engineering And Regenerative Medicine

Author by : Ulrich Meyer
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 77
Total Download : 761
File Size : 45,6 Mb
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Description : "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.


Methods Of Tissue Engineering

Author by : Anthony Atala
Languange : en
Publisher by : Gulf Professional Publishing
Format Available : PDF, ePub, Mobi
Total Read : 81
Total Download : 403
File Size : 50,9 Mb
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Description : This book will be a resource for the experienced tissue engineer, a starting point for the student, and a guidebook for the next generation of tissue engineers. Contained in one volume is a comprehensive reference that combines the tools, experimental protocols, detailed descriptions, and "know-how" for the successful engineering of tissues and organs. The practical information contained in the numerous protocols covers every area of tissue engineering and will prove essential to scientists working in this field. Contributions by leaders in the latest areas of research will also be of interest to biotechnological and pharmaceutical researchers. Key Features * Provides comprehensive protocols covering every area of tissue engineering, including polymer synthesis, cell culture, encapsulation, bioreactors, therapeutics, and the creation of tissues and organs; * Includes contributions by leaders in the latest areas of research, such as stem cells and fetal tissue engineering


Culture Of Cells For Tissue Engineering

Author by : Gordana Vunjak-Novakovic
Languange : en
Publisher by : John Wiley & Sons
Format Available : PDF, ePub, Mobi
Total Read : 89
Total Download : 379
File Size : 50,9 Mb
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Description : Step-by-step, practical guidance for the acquisition, manipulation,and use of cell sources for tissue engineering Tissue engineering is a multidisciplinary field incorporatingthe principles of biology, chemistry, engineering, and medicine tocreate biological substitutes of native tissues for scientificresearch or clinical use. Specific applications of this technologyinclude studies of tissue development and function, investigatingdrug response, and tissue repair and replacement. This area israpidly becoming one of the most promising treatment options forpatients suffering from tissue failure. Written by leading experts in the field, Culture of Cellsfor Tissue Engineering offers step-by-step, practicalguidance for the acquisition, manipulation, and use of cell sourcesfor tissue engineering. It offers a unique focus on tissueengineering methods for cell sourcing and utilization, combiningtheoretical overviews and detailed procedures. Features of the text include: Easy-to-use format with a two-part organization Logically organized—part one discusses cell sourcing,preparation, and characterization and the second part examinesspecific engineered tissues Each chapter covers: structural and functional properties oftissues, methodological principles, culture, cellselection/expansion, cell modifications, cell seeding, tissueculture, analytical assays, and a detailed description ofrepresentative studies End-of-chapter features include useful listings of sources forreagents, materials, and supplies, with the contact details of thesuppliers listed at the end of the book A section of elegant color plates to back up the figures in thechapters Culture of Cells for Tissue Engineering givesnovice and seasoned researchers in tissue engineering an invaluableresource. In addition, the text is suitable for professionals inrelated research, particularly in those areas where cell and tissueculture is a new or emerging tool.


Stem Cells And Tissue Engineering

Author by : Mirjana Pavlovic
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 52
Total Download : 153
File Size : 51,5 Mb
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Description : Stem cells are the building blocks for all other cells in an organism. The human body has about 200 different types of cells and any of those cells can be produced by a stem cell. This fact emphasizes the significance of stem cells in transplantational medicine, regenerative therapy and bioengineering. Whether embryonic or adult, these cells can be used for the successful treatment of a wide range of diseases that were not treatable before, such as osteogenesis imperfecta in children, different forms of leukemias, acute myocardial infarction, some neural damages and diseases, etc. Bioengineering, e.g. successful manipulation of these cells with multipotential capacity of differentiation toward appropriate patterns and precise quantity, are the prerequisites for successful outcome and treatment. By combining in vivo and in vitro techniques, it is now possible to manage the wide spectrum of tissue damages and organ diseases. Although the stem-cell therapy is not a response to all the questions, it provides more and more answers every day. Stem Cells and Tissue Engineering is a concise review on the functional, phenotypic, regenerative, transplantational and curative aspects of a stem cell’s entity. It is critical and encouraging at the same time, providing truthful and appropriate samples from the practice and research that can lead toward optimal use of this immense source of adjuvant and curative therapy in human pathology. Written by a clinician and a researcher, who are currently teaching what they are doing, it is recommended as a teaching tool along with an original textbook.


Tissue Engineering

Author by : Clemens Van Blitterswijk
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 72
Total Download : 975
File Size : 45,6 Mb
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Description : Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering


Advances In Tissue Engineering

Author by : Julia M. Polak
Languange : en
Publisher by : Imperial College Press
Format Available : PDF, ePub, Mobi
Total Read : 42
Total Download : 225
File Size : 51,9 Mb
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Description : Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field.


Tissue Engineering

Author by : Clemens Van Blitterswijk
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 99
Total Download : 335
File Size : 42,8 Mb
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Description : Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering


Frontiers In Tissue Engineering

Author by : C.W. Patrick
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 37
Total Download : 177
File Size : 41,6 Mb
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Description : Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.


Stem Cell Transplantation And Tissue Engineering

Author by : A. Haverich
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 49
Total Download : 414
File Size : 42,6 Mb
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Description : As dogmas in stem cell research are losing their impact and recent findings regarding the use and cultivation of stem cells and tissue transplantation have opened up new therapeutic avenues, this Ernst Schering Research Foundation Workshop was initiated to highlight current and future approaches in this field. The only stem cells that have been used clinically for a long time is the hematopoietic stem cell as a source for bone marrow transplantation. Recent findings now indicate that hematopoietic stem cells, under certain conditions, are able to differentiate into endothelial, neural or muscle cells, providing exciting new therapeutic possibilities. They represent a future source for tissue engineering replacing defective cells or tissues and allowing diseased organs to regain their functions. Both reconstitution techniques are paving the way for the development of new therapeutic strategies, giving hope of being able to cure and not only treat patients.


Nanostructures For The Engineering Of Cells Tissues And Organs

Author by : Alexandru Mihai Grumezescu
Languange : en
Publisher by : William Andrew
Format Available : PDF, ePub, Mobi
Total Read : 72
Total Download : 229
File Size : 49,9 Mb
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Description : Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine


Handbook Of Tissue Engineering Scaffolds Volume Two

Author by : Masoud Mozafari
Languange : en
Publisher by : Woodhead Publishing
Format Available : PDF, ePub, Mobi
Total Read : 69
Total Download : 438
File Size : 41,9 Mb
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Description : Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems. Dedicated to the specialist topic of composite scaffolds, featuring all human body systems Covers basic fundamentals and advanced clinical applications Includes up-to-date information on preparation methodology and characterization techniques Highlights clinical data and case studies


Tissue Engineering Iii Cell Surface Interactions For Tissue Culture

Author by : Cornelia Kasper
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 65
Total Download : 122
File Size : 49,9 Mb
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Description : The Cell-Surface Interaction, by J. S. Hayes, E. M. Czekanska and R. G. Richards. Studying Cell-Surface Interactions In Vitro: A Survey of Experimental Approaches and Techniques, by Stefanie Michaelis, Rudolf Robelek and Joachim Wegener. Harnessing Cell-Biomaterial Interactions for Osteochondral Tissue Regeneration, by Kyobum Kim, Diana M. Yoon, Antonios G. Mikos and F. Kurtis Kasper. Interaction of Cells with Decellularized Biological Materials, by Mathias Wilhelmi, Bettina Giere and Michael Harder. Evaluation of Biocompatibility Using In Vitro Methods: Interpretation and Limitations, by Arie Bruinink and Reto Luginbuehl. Artificial Scaffolds and Mesenchymal Stem Cells for Hard Tissues, by Margit Schulze and Edda Tobiasch. Bioactive Glass-Based Scaffolds for Bone Tissue Engineering, by Julia Will, Lutz-Christian Gerhardt and Aldo R. Boccaccini. Microenvironment Design for Stem Cell Fate Determination, by Tali Re’em and Smadar Cohen. Stem Cell Differentiation Depending on Different Surfaces, by Sonja Kress, Anne Neumann, Birgit Weyand and Cornelia Kasper. Designing the Biocompatibility of Biohybrids, by Frank Witte, Ivonne Bartsch and Elmar Willbold. Interaction of Cartilage and Ceramic Matrix, by K. Wiegandt, C. Goepfert, R. Pörtner and R. Janssen. Bioresorption and Degradation of Biomaterials, by Debarun Das, Ziyang Zhang, Thomas Winkler, Meenakshi Mour, Christina I. Günter, Michael M. Morlock, Hans-Günther Machens and Arndt F. Schilling.


Tissue Engineering

Author by : W. Mark Saltzman
Languange : en
Publisher by : Oxford University Press
Format Available : PDF, ePub, Mobi
Total Read : 88
Total Download : 718
File Size : 44,9 Mb
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Description : Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery.


Principles Of Tissue Engineering

Author by : Robert Lanza
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 83
Total Download : 356
File Size : 50,6 Mb
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Description : Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout


Stem Cell And Tissue Engineering

Author by : Dr.Sumira Malik
Languange : en
Publisher by : Sankalp Publication
Format Available : PDF, ePub, Mobi
Total Read : 57
Total Download : 344
File Size : 43,7 Mb
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Description : This book requires the basic knowledge of human physiology, cell biology, Molecular Biology, Animal biotechnology and Biochemistry. The goal of this book is to provide students, teachers and researchers the essence of the key concepts and deep knowledge of stem cells basics, stem cell technology and their application in field of regenerative medicine applying these thematic studies of stem cell technology and tissue engineering. Stem cell technology and it’s application in Tissue engineering is an interdisciplinary field of biomedical research compiling Biosciences, material sciences and Bioengineering to progress the treatment of damaged, degenerated and diseased tissue through maintenance, repair, and replacement methodology. This ever-emerging area of research applies in numerous medical and interdisciplinary streams of stem cell biology, tissue regeneration, regenerative medicine and Bioengineering. These stem cell biology techniques and tissue engineering strategies are now being progressively more evaluated and progressed as potential treatments of neuro degeneration disorders, regenerative medicine, artificial organ development, organ bioengineering, and transplant medicine. The book seeks to put an end to many queries and doubts about an understanding of the clinical need for stem cell therapy and tissue engineering in regenerative medicine, knowledge of stem cell sources and their isolation, characterization, principle of tissue engineering using basic elements and concept of tissue engineering. Further, the need for biomaterials, their design, fabrication and used of the biomaterials for in vitro, in vivo and clinical application are also covered. This book discusses the emergence of stem cell technology, tissue engineering and our current understanding of the Biotechnology and Biological sciences discipline


Tissue Engineering

Author by : Bernhard Palsson
Languange : en
Publisher by : Prentice Hall
Format Available : PDF, ePub, Mobi
Total Read : 86
Total Download : 135
File Size : 45,9 Mb
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Description : For senior-level and first-year graduate courses in Tissue Engineering, in departments of bioengineering; and for students researching tissue replacement and restorations; as well as students of biology medicine and life science working with primary and complex cell biology. This text-the first in its field-lays the foundation for students studying tissue engineering. It provides a conceptual framework that includes exposure to all the necessary background material in all areas.


Micro And Nanotechnologies In Engineering Stem Cells And Tissues

Author by : Murugan Ramalingam
Languange : en
Publisher by : John Wiley & Sons
Format Available : PDF, ePub, Mobi
Total Read : 59
Total Download : 736
File Size : 54,8 Mb
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Description : A cutting-edge look at the application of micro andnanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stemcells/tissue engineering has seen an explosion of activity inrecent years. This book provides a much-needed overview of theseexciting developments, covering all aspects of micro andnanotechnologies, from the fundamental principles to the latestresearch to applications in regenerative medicine. Written and edited by the top researchers in the field, Microand Nanotechnologies in Engineering Stem Cells and Tissuesdescribes advances in material systems along with currenttechniques available for cell, tissue, and organ studies. Readerswill gain tremendous insight into the state of the art of stemcells and tissue engineering, and learn how to use the technologyin their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissuegrowth Various engineering approaches for stem cell, vascular tissue,and bone regeneration The design and processing of biocompatible polymers and otherbiomaterials Characterization of the interactions between cells andbiomaterials Unrivaled among books of this kind, Micro andNanotechnologies in Engineering Stem Cells and Tissues is theultimate forward-looking reference for researchers in numerousdisciplines, from engineering and materials science to biomedicine,and for anyone wishing to understand the trends in thistransformative field.


Stem Cells Tissue Engineering And Regenerative Medicine

Author by : David Warburton
Languange : en
Publisher by : World Scientific
Format Available : PDF, ePub, Mobi
Total Read : 51
Total Download : 125
File Size : 44,5 Mb
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Description : Stem cells, tissue engineering and regenerative medicine are fast moving fields with vastly transformative implications for the future of health care and capital markets. This book will show the state of the art in the translational fields of stem cell biology, tissue engineering and regenerative medicine. The state of developments in specific organ systems, where novel solutions to organ failure are badly needed such as the lungs, kidney and so forth, are discussed in various chapters. These present and future advances are placed in the context of the overall field, offering a comprehensive and quick up-to-date drink from the fountain of knowledge in this rapidly emerging field. This book provides an investigator-level overview of the current field accessible to the educated scientific generalist as well as a college educated readership, undergraduates and science writers, educators and professionals of all kinds. Contents:Developmental Biology, Regenerative Medicine and Stem Cells: The Hope Machine is Justified (David Warburton)Towards Broader Approaches to Stem Cell Signaling and Therapeutics (Edwin Jesudason)Pluripotent Stem Cells from the Early Embryo (Claire E Cuddy and Martin F Pera)The First Cell Fate Decision During Mammalian Development (Melanie D White and Nicolas Plachta)Asymmetric Cell Divisions of Stem/Progenitor Cells (Ahmed HK El-Hashash)Microenvironmental Modulation of Stem Cell Differentiation with Focus on the Lung (Shimon Lecht, Collin T Stabler, Seda Karamil, Athanasios Mantalaris, Ali Samadikuchaksaraei, Julia M Polak and Peter I Lelkes)Smart Matrices for Distal Lung Tissue Engineering (Mark J Mondrinos and Peter I Lelkes)Skin Stem Cells and Their Roles in Skin Regeneration and Disorders (Chao-Kai Hsu, Chao-Chun Yang and Shyh-Jou Shieh)Stem Cell Recruitment and Impact in Skin Repair and Regeneration (Tim Hsu, Tai-Lan Tuan and Yun-Shain Lee)Epigenetic and Environmental Regulation of Skin Appendage Regeneration (Ting-Xin Jiang, Chih-Chiang Chen, Michael W Hughes, Cheng-Ming Chuong and Randall Widelitz)Cranial Neural Crest: An Extraordinarily Migratory and Multipotent Embryonic Cell Population (Samuel G Cox and J Gage Crump)Modeling Neurodegenerative Diseases and Neurodevelopmental Disorders with Reprogrammed Cells (Kate E Galloway and Justin K Ichida)Cytokine Regulation of Intestinal Stem Cells (Philip E Dubé, Unice J K Soh and D Brent Polk)The Intestinal Stem Cell Niche and Its Regulation by ErbB Growth Factor Receptors (Dana Almohazey and Mark R Frey)Tissue Engineering: Intestine (Avafia Y Dossa, Kathy A Schall, Tracy C Grikscheit and Christopher P Gayer)Liver Stem and Progenitor Cells in Development, Disease and Regenerative Medicine (Nirmala Mavila and Kasper S Wang)Lung Mesenchymal Stem Cells (Wei Shi)FGF Signaling in Lung Stem and Progenitor Cells (Soula Danopoulos and Denise Al Alam)Bioengineering Distal Airways (Christine Finck and Todd Jensen)The Isolation and Molecular Characterization of Cancer Stem Cells (Aggressive Endophenotypes) in Individual Lung Cancers (Raj K Batra, Scott Oh and Saroj Basak)Mesenchymal Stromal Cell-Based Therapies for Lung Diseases and Critical Illnesses (Fernanda Cruz, Patricia RM Rocco and Daniel J Weiss)Heart Regeneration and Repair: What We Have Learned from Model Organisms (Laurent Gamba, Michael R Harrison and Ching-Ling Lien)Leveraging Structure-Based Rational Drug Design and Nanotechnology to Destroy Leukemic Stem Cells (Fatih M Uckun, Jianjun Cheng, Cheney Mao and Sanjive Qazi)Placenta-Derived Stem Cells: Development and Preclinical Applications for Regenerative Medicine (Jennifer Izumi Divine, Hee Kyung Jung and Toshio Miki)Stem Cells in the Real World: Environmental Impacts (Theresa M Bastain, Lu Gao and Frank D Gilliland)Establishing a Research Grade Human Pluripotent Stem Cell Laboratory (Laura-Marie Nucho and Victoria Fox) Readership: Stem cell and tissue engineering scientists, patient advocates, educated laypeople, high school science students, undergraduate students, graduate students, physicians and surgeons. Key Features:This book presents up-to-date latest breakthroughs and near future applicationsBench to bedsideThis book features potential curesKeywords:Stem Cells;Tissue Engineering;Regenerative Medicine


Developmental Biology And Musculoskeletal Tissue Engineering

Author by : Martin J. Stoddart
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 96
Total Download : 221
File Size : 46,8 Mb
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Description : Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair


Artificial Cells Cell Engineering And Therapy

Author by : S Prakash
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 55
Total Download : 448
File Size : 42,5 Mb
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Description : Artificial cells, cell engineering and therapy are emerging technologies which will make a significant impact on the future of medicine and healthcare. However, research within the field is vast. This unique book provides a comprehensive study of the most recent advances in the field and its practical applications. The first part of the book offers the reader an introduction to the basics of artificial cell technology with chapters on its origins, design, current status within medicine and future prospects. Part two covers apoptosis, the use of bone marrow stromal cells in myocardial regeneration together with signalling and tissue engineering. Part three discusses artificial cells for therapy, procedures for various clinical conditions and the current status of the discipline within the field. The book concludes with a final section on the role of artificial cells in medicine with particular focus on the use of artificial cells as blood substitutes and their potential use in myocardial regeneration, drug delivery and in treating kidney and bowel diseases, diabetes and cancer. Artificial cells, cell engineering and therapy is a valuable reference for researchers, students and practitioners within the field. Introduces the basics of artificial cell technology Provides a comprehensive study of the most recent advances in artificial cells, cell engineering and cell therapy Discusses the design, engineering and uses of artificial cells


Cell And Tissue Engineering

Author by : Bojana Obradović
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 89
Total Download : 164
File Size : 41,7 Mb
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Description : “Cell and Tissue Engineering” introduces the principles and new approaches in cell and tissue engineering. It includes both the fundamentals and the current trends in cell and tissue engineering, in a way useful both to a novice and an expert in the field. The book is composed of 13 chapters all of which are written by the leading experts. It is organized to gradually assemble an insight in cell and tissue function starting form a molecular nano-level, extending to a cellular micro-level and finishing at the tissue macro-level. In specific, biological, physiological, biophysical, biochemical, medical, and engineering aspects are covered from the standpoint of the development of functional substitutes of biological tissues for potential clinical use. Topics in the area of cell engineering include cell membrane biophysics, structure and function of the cytoskeleton, cell-extracellular matrix interactions, and mechanotransduction. In the area of tissue engineering the focus is on the in vitro cultivation of functional tissue equivalents based on the integrated use of isolated cells, biomaterials, and bioreactors. The book also reviews novel techniques for cell and tissue imaging and characterization, some of which are described in detail such as atomic force microscopy. Finally, mathematical modeling methods are presented as valuable and indispensable tools in cell and tissue engineering. Numerous illustrations enhance the quality and ease of use of the presented material.


Engineering Stem Cells For Tissue Regeneration

Author by : Li Song
Languange : en
Publisher by : World Scientific
Format Available : PDF, ePub, Mobi
Total Read : 60
Total Download : 704
File Size : 50,7 Mb
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Description : Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students. Contents: Tissue Engineering: From Basic Biology to Cell-Based Applications (R M Nerem)Recent Advances and Future Perspectives on Somatic Cell Reprogramming (K-Y Kim & I-H Park)Hematopoietic Stem Cells (J J Trowbridge)Mesenchymal Stem Cells for Tissue Regeneration (N F Huang & S Li)Delivery Vehicles for Deploying Mesenchymal Stem Cells in Tissue Repair (M S Friedman & J K Leach)Stem Cells for Cardiac Tissue Engineering (J L Young et al.)Cardiovascular System: Stem Cells in Tissue-Engineered Blood Vessels (R Sawh-Martinez et al.)Stem Cells for Vascular Regeneration: An Engineering Approach (L E Dickinson & S Gerecht)Stem Cells and Wound Repair (S H Ko et al.)Engineering Cartilage: From Materials to Small Molecules (J M Coburn & J H Elisseeff)Adult Stem Cells for Articular Cartilage Tissue Engineering (S Saha et al.)Stem Cells for Disc Repair (A A Allon et al.)Skeletal Tissue Engineering: Progress and Prospects (N J Panetta et al.)Clinical Applications of a Stem Cell Based Therapy for Oral Bone Reconstruction (B McAllister & K Haghighat)Therapeutic Strategies for Repairing the Injured Spinal Cord Using Stem Cells (M S Beattie & J C Bresnahan)Potential of Tissue Engineering and Neural Stem Cells in the Understanding and Treatment of Neurodegenerative Diseases (C Auclair-Daigle & F Berthod)High-Throughput Systems for Stem Cell Engineering (D A Brafman et al.)Microscale Technologies for Tissue Engineering and Stem Cell Differentiation (J W Nichol et al.)Quality Control of Autologous Cell- and Tissue-Based Therapies (N Dusserre et al.)Regulatory Challenges for Cell-Based Therapeutics (T McAllister et al.) Readership: Life science scientists; biomedical researchers; cell biologists; academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals. Keywords: Stem Cells;Tissue Engineering;Regenerative Medicine;Biotechnology;Cell EngineeringReview:0


Molecular Cellular And Tissue Engineering

Author by : Joseph D. Bronzino
Languange : en
Publisher by : CRC Press
Format Available : PDF, ePub, Mobi
Total Read : 21
Total Download : 127
File Size : 51,5 Mb
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Description : Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine. More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.


Principles Of Regenerative Medicine

Author by : Anthony Atala
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 48
Total Download : 370
File Size : 51,5 Mb
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Description : Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs


Innovations In Molecular Mechanisms And Tissue Engineering

Author by : Jeanne Wilson-Rawls
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 28
Total Download : 646
File Size : 54,5 Mb
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Description : This book marries stem cell biology, tissue engineering, and regenerative biology into a single, interdisciplinary volume. The chapters also explore embryonic stem cells, induced pluripotent stem cells, cardiovascular regeneration, skeletal development, inflammation, polymeric biomaterials, neural injury, cartilage regeneration, regeneration in ambystoma, models for regeneration using salamander and zebrafish, and more. The volume also discusses recent advances and their potential in developing future therapies. Innovations in Molecular Mechanisms and Tissue Engineering combines perspectives from the biomedical, bioengineering, and medical fields to present a cutting-edge, multifaceted picture of the tissue engineering and regenerative medicine fields. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is ideal for scientists, clinicians, and researchers in the fields of stem cell biology, regenerative medicine, biomedical engineering, and tissue engineering.


Cell Engineering And Regeneration

Author by : Heinz Redl
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 57
Total Download : 148
File Size : 45,9 Mb
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Description : This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.


3d Cell Culture

Author by : Ranjna C. Dutta
Languange : en
Publisher by : CRC Press
Format Available : PDF, ePub, Mobi
Total Read : 69
Total Download : 963
File Size : 52,7 Mb
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Description : 3D cell culture is yet to be adopted and exploited to its full potential. It promises to upgrade and bring our understanding about human physiology to the highest level with the scope of applying the knowledge for better diagnosis as well as therapeutics. The focus of this book is on the direct impact of novel technologies and their evolution into viable products for the benefit of human race. It also describes the fundamentals of cell microenvironment to bring forth the relevance of 3D cell culture in tissue engineering and regenerative medicine. It discusses the extracellular matrix/microenvironment (ECM) and emphasizes its significance for growing cells in 3D to accomplish physiologically viable cell mass/tissue ex vivo. The book bridges the knowledge gaps between medical need and the technological applications through illustrations. It discusses the available models for 3D cell culture as well as the techniques to create substrates and scaffolds for achieving desired 3D microenvironment.