Centrifugal Separations in Biotechnology

Centrifugal Separations in Biotechnology
Author: Wallace Woon-Fong Leung
Publsiher: Butterworth-Heinemann
Total Pages: 502
Release: 2020-03-13
ISBN: 0081026358
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Centrifugal Separations in Biotechnology Book Excerpt:

Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more

Membrane Separations in Biotechnology

Membrane Separations in Biotechnology
Author: McGregor
Publsiher: Marcel Dekker Incorporated
Total Pages: 386
Release: 1986
ISBN: 1928374650XXX
Category: Biomolecules
Language: EN, FR, DE, ES & NL

Membrane Separations in Biotechnology Book Excerpt:

Bioseparations Science and Engineering

Bioseparations Science and Engineering
Author: Roger G. Harrison,Paul W. Todd,Scott R. Rudge,Demetri P. Petrides
Publsiher: Oxford University Press
Total Pages: 432
Release: 2015-01-27
ISBN: 0190213744
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Bioseparations Science and Engineering Book Excerpt:

Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.

Separations for Biotechnology

Separations for Biotechnology
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1994
ISBN: 1928374650XXX
Category: Biomolecules
Language: EN, FR, DE, ES & NL

Separations for Biotechnology Book Excerpt:

Separations for Biotechnology 3

Separations for Biotechnology 3
Author: D. L. Pyle
Publsiher: CRC PressI Llc
Total Pages: 603
Release: 1994
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Separations for Biotechnology 3 Book Excerpt:

Bioseparation is a technique by which the products of fermentations or biotransformations are recovered for subsequent use. This volume explores the technical problems posed by bioprocessing, and the importance of the recovery of pure biological products for product safety and quality.

Continuous Manufacturing of Pharmaceuticals

Continuous Manufacturing of Pharmaceuticals
Author: Peter Kleinebudde,Johannes Khinast,Jukka Rantanen
Publsiher: John Wiley & Sons
Total Pages: 632
Release: 2017-07-14
ISBN: 1119001358
Category: Science
Language: EN, FR, DE, ES & NL

Continuous Manufacturing of Pharmaceuticals Book Excerpt:

A comprehensive look at existing technologies and processes for continuous manufacturing of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical industry has come under intense pressure to improve the efficiency of its manufacturing processes. Continuous process manufacturing provides a proven solution. Among its many benefits are: minimized waste, energy consumption, and raw material use; the accelerated introduction of new drugs; the use of smaller production facilities with lower building and capital costs; the ability to monitor drug quality on a continuous basis; and enhanced process reliability and flexibility. Continuous Manufacturing of Pharmaceuticals prepares professionals to take advantage of that exciting new approach to improving drug manufacturing efficiency. This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. Brings together the essential know-how for anyone working in drug manufacturing, as well as chemical, food, and pharmaceutical scientists working on continuous processing Covers chemical engineering principles, regulatory aspects, primary and secondary manufacturing, process analytical technology and quality-by-design Contains contributions from researchers in leading pharmaceutical companies, the FDA, and academic institutions Offers an extremely well-informed look at the most promising future approaches to continuous manufacturing of innovative pharmaceutical products Timely, comprehensive, and authoritative, Continuous Manufacturing of Pharmaceuticals is an important professional resource for researchers in industry and academe working in the fields of pharmaceuticals development and manufacturing.

Separation Processes in Biotechnology

Separation Processes in Biotechnology
Author: Juan A. Asenjo
Publsiher: CRC Press
Total Pages: 824
Release: 2020-08-27
ISBN: 1000147533
Category: Medical
Language: EN, FR, DE, ES & NL

Separation Processes in Biotechnology Book Excerpt:

Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations

Chemical Engineering Problems in Biotechnology

Chemical Engineering Problems in Biotechnology
Author: Michael A. Winkler,M. Winkler
Publsiher: Springer Science & Business Media
Total Pages: 370
Release: 1990-04-30
ISBN: 9781851664542
Category: Science
Language: EN, FR, DE, ES & NL

Chemical Engineering Problems in Biotechnology Book Excerpt:

Protein Biotechnology

Protein Biotechnology
Author: Felix Franks
Publsiher: Springer Science & Business Media
Total Pages: 592
Release: 1993-06-14
ISBN: 0896032302
Category: Science
Language: EN, FR, DE, ES & NL

Protein Biotechnology Book Excerpt:

Proteins are the servants of life. They occur in all com- nent parts of living organisms and are staggering in their fu- tional variety, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different p- teins, fulfilling a wide range of life-supporting roles. Additions to the total number of known proteins are being made on an increasing scale through the discovery of mutant strains or their production by genetic manipulation. The total international protein literature could fill a medi- sized building and is growing at an ever-increasing rate. The reader might be forgiven for asking whether yet another book on proteins, their properties, and functions can serve a useful purpose. An explanation of the origin of this book may serve as justification. The authors form the tutorial team for an int- sive postexperience course on protein characterization or- nized by the Center for Professional Advancement, East Brunswick, New Jersey, an educational foundation. The course was first mounted in Amsterdam in 1982 and has since been repeated several times, in both Amsterdam and the US, with participants from North America and most European countries. In a predecessor to this book, emphasis was placed on the role of protein isolation in the food industry, because at the time this reflected the interests of most of the participants at the course. Today, isolated proteins for food use are extracted from yeasts, fungal sources, legumes, oilseeds, cereals, and leaves.

Biotechnology Bioprocessing

Biotechnology  Bioprocessing
Author: Hans-Jürgen Rehm,Gerald Reed,G. Stephanopoulos,Alfred Pühler,P. Stadler
Publsiher: Vch Pub
Total Pages: 816
Release: 1991
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Biotechnology Bioprocessing Book Excerpt:

Natural Products Isolation

Natural Products Isolation
Author: Richard J. P. Cannell
Publsiher: Springer Science & Business Media
Total Pages: 473
Release: 1998
ISBN: 0896033627
Category: Science
Language: EN, FR, DE, ES & NL

Natural Products Isolation Book Excerpt:

Natural Products Isolation provides a comprehensive introduction to techniques for the extraction and purification of natural products from all biological sources. Geared to scientists with little experience of natural products extraction, but offering even skilled researchers valuable advice and insight, Natural Products Isolation lays the foundation for the potential extractor to isolate natural substances efficiently. Its methods and guidance will almost certainly play a major role in today's natural product discovery and development.

Bioprocess Engineering

Bioprocess Engineering
Author: Pau Loke Show,Chien Wei Ooi,Tau Chuan Ling
Publsiher: CRC Press
Total Pages: 210
Release: 2019-05-24
ISBN: 0429882513
Category: Medical
Language: EN, FR, DE, ES & NL

Bioprocess Engineering Book Excerpt:

Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Biopharmaceutical Manufacturing

Biopharmaceutical Manufacturing
Author: Gary Gilleskie,Charles Rutter,Becky McCuen
Publsiher: Walter de Gruyter GmbH & Co KG
Total Pages: 347
Release: 2021-09-06
ISBN: 3110617013
Category: Science
Language: EN, FR, DE, ES & NL

Biopharmaceutical Manufacturing Book Excerpt:

Biopharmaceuticals, medicines made by or from living organisms (including cells from living organisms), are extremely effective in treating a broad range of diseases. Their importance to human health has grown significantly over the years as more biopharmaceutical products have entered the market, and now the biggest selling drugs in the world are biopharmaceuticals. Biopharmaceutical Manufacturing: Principles, Processes and Practices provides concise, comprehensive, and up-to-date coverage of biopharmaceutical manufacturing. Written in a clear and informal style, the content has been influenced by the authors’ substantial industry experience and teaching expertise. That expertise enables the authors to address the many questions posed over the years both by university students and professionals with experience in the field. Consequently, the book will appeal both to undergraduate or graduate students using it as a textbook and specialized industry practitioners seeking to understand the big picture of biopharmaceutical manufacturing. This book:

Bioseparations of Proteins

Bioseparations of Proteins
Author: Ajit Sadana
Publsiher: Elsevier
Total Pages: 346
Release: 1997-11-27
ISBN: 9780080528144
Category: Science
Language: EN, FR, DE, ES & NL

Bioseparations of Proteins Book Excerpt:

This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption,process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures

Handbook of Methods and Instrumentation in Separation Science

Handbook of Methods and Instrumentation in Separation Science
Author: Anonim
Publsiher: Academic Press
Total Pages: 880
Release: 2009-11-11
ISBN: 9780123757272
Category: Science
Language: EN, FR, DE, ES & NL

Handbook of Methods and Instrumentation in Separation Science Book Excerpt:

Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. One-stop source for information on separation methods General overviews for quick orientation Ease of use for finding results fast Expert coverage of major separation methods Coverage of techniques for all sizes of samples, pico-level to kilo-level

Solid liquid Separation Practice III

Solid liquid Separation Practice III
Author: Peter Snowdon
Publsiher: Chem/Mats-Sci/E
Total Pages: 326
Release: 1989
ISBN: 1928374650XXX
Category: Separation (Technology)
Language: EN, FR, DE, ES & NL

Solid liquid Separation Practice III Book Excerpt:

Reflecting growing interest in this field, this volume presents current advances in the fields of hydrocyclones, solids washing and dewatering, new processes, membrane and crossflow filtration, coal and metals, biotechnology/thermodynamics, clarification and sedimentation/ centrifugation.

Solid Liquid Separation Practice III

Solid Liquid Separation Practice III
Author: Institution of Chemical Engineers (Great Britain). Yorkshire Branch,Filtration Society (Great Britain)
Publsiher: Hemisphere Pub
Total Pages: 326
Release: 1989
ISBN: 9780852952405
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Solid Liquid Separation Practice III Book Excerpt:

Solid liquid Separation Practice III

Solid liquid Separation Practice III
Author: Anonim
Publsiher: Unknown
Total Pages: 326
Release: 1989
ISBN: 1928374650XXX
Category: Separation (Technology)
Language: EN, FR, DE, ES & NL

Solid liquid Separation Practice III Book Excerpt:

Food Biochemistry and Food Processing

Food Biochemistry and Food Processing
Author: Benjamin K. Simpson
Publsiher: John Wiley & Sons
Total Pages: 912
Release: 2012-04-11
ISBN: 1118308050
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Food Biochemistry and Food Processing Book Excerpt:

The biochemistry of food is the foundation on which the research and development advances in food biotechnology are built. In Food Biochemistry and Food Processing, Second Edition, the editors have brought together more than fifty acclaimed academicians and industry professionals from around the world to create this fully revised and updated edition. This book is an indispensable reference and text on food biochemistry and the ever increasing developments in the biotechnology of food processing. Beginning with sections on the essential principles of food biochemistry, enzymology, and food processing, the book then takes the reader on commodity-by-commodity discussions of biochemistry of raw materials and product processing. Chapters in this second edition have been revised to include safety considerations and the chemical changes induced by processing in the biomolecules of the selected foodstuffs. This edition also includes a new section on health and functional foods, as well as ten new chapters including those on thermally and minimally processed foods, separation technology in food processing, and food allergens. Food Biochemistry and Food Processing, second edition fully develops and explains the biochemical aspects of food processing, and brings together timely and relevant topics in food science and technology in one package. This book is an invaluable reference tool for professional food scientists, researchers and technologists in the food industry, as well as faculty and students in food science, food technology and food engineering programs. The Editor Dr. Benjamin K. Simpson, Department of Food Science and Agricultural Chemistry, McGill University, Quebec, Canada Associate Editors Professor Leo Nollet, Department of Applied Engineering Sciences, Hogeschool Ghent, Belgium Professor Fidel Toldrá, Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Valencia, Spain Professor Soottawat Benjakul, Department of Food Technology, Prince of Songkla University, Songkhla, Thailand Professor Gopinadhan Paliyath, Department of Plant Agriculture, University of Guelph, Ontario, Canada Dr. Y. H. Hui, Consultant to the Food Industry, West Sacramento, California, USA

International Biotechnology Directory

International Biotechnology Directory
Author: J. Coombs,Y.R. Alston
Publsiher: Springer
Total Pages: 649
Release: 2016-01-07
ISBN: 1349135690
Category: Science
Language: EN, FR, DE, ES & NL

International Biotechnology Directory Book Excerpt:

This directory provides the reader with quick-access to information on more than 8000 companies, research centres and academic institutions involved in new and established technologies. This edition offers more than 600 all-new organization listings, including new listings in Europe.