New Approaches For Flavin Catalysis

Author by : Anonim
Languange : en
Publisher by : Academic Press
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Description : New Approaches for Flavin Catalysis, Volume 620, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this update include Anaerobiosis and Methods for Reduction, Reduction Potentials, Anaerobic Stopped-Flow, No Glove-Box, Anaerobic Stopped-Flow, in a Glove-Box, Chemical Quenching, Oxygen Reactions, Double-mixing Stopped-Flow, Kinetic Isotope Effects and Viscosity Effects, Heavy Enzymes Synthetic Flavins & Linear Free Energy Relationships, Vibrational Spectroscopy, Stark Spectroscopy, EPR and Related Methods, Molecular Dynamics, Phylogenetic Relationships/Superfamilies, O2 and Superoxide Analogs, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Updated release includes the latest information on New Approaches for Flavin Catalysis


Organic Chemistry Of Enzyme Catalyzed Reactions Revised Edition

Author by : Richard B. Silverman
Languange : en
Publisher by : Elsevier
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Description : The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style


Research Awards Index

Author by : Anonim
Languange : en
Publisher by : Unknown
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Research Grants Index

Author by : National Institutes of Health (U.S.). Division of Research Grants
Languange : en
Publisher by : Unknown
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Mechanical Catalysis

Author by : Gerhard Swiegers
Languange : en
Publisher by : John Wiley & Sons
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Total Read : 75
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Description : Provides a clear and systematic description of the key role played by catalyst reactant dynamism including: (i) the fundamental processes at work, (ii) the origin of its general and physical features, (iii) the way it has evolved, and (iv) how it relates to catalysis in man-made systems. Unifies homogeneous, heterogeneous, and enzymatic catalysis into a single, conceptually coherent whole. Describes how to authentically mimic the underlying principles of enzymatic catalysis in man-made systems. Examines the origin and role of complexity and complex Systems Science in catalysis--very hot topics in science today.


Cumulated Index Medicus

Author by : Anonim
Languange : en
Publisher by : Unknown
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Asymmetric Catalysis On Industrial Scale

Author by : Hans Ulrich Blaser
Languange : en
Publisher by : John Wiley & Sons
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Total Read : 35
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Description : This second edition of the pioneering work on this hot topic captures the major trends and latest achievements in the art of asymmetric catalysis on an industrial scale. A number of completely new real-life case studies written by the world leaders in their respective areas provide a compact and qualified insight into this developing field. The resulting ready reference and handbook collates first-hand and valuable information within a context where it can be easily found. The high-quality contributions illustrate the relevant environments and situations, such as time pressure, how the catalytic step fits into the overall synthesis, or competition with other synthetic approaches, as well as the typical problems encountered in the various phases, including finding/developing the catalyst and optimization of the process or choice of equipment. Both successful and unsuccessful approaches to solve these problems are described.


Enzyme Catalysis And Control

Author by : Marlene Deluca
Languange : en
Publisher by : Elsevier
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Description : Current Topics in Cellular Regulation: Volume 24, Enzyme Catalysis and Control is a compendium of papers that discusses phosphoryl transfer reactions, the role of water on the free energy of hydrolysis of pyrophosphate, and the hormonal actions of vitamin D. Other papers describe the regulation lipid metabolism by a lipid-carrying protein, the GABA, and taurine enzymes in mammalian brain. One paper examines the role of vitamin D in the metabolism of cells, as well as in the whole animal. Upon absorption in the body, the vitamin undergoes various metabolic transformations before interacting with specific receptors, and then inducting the genome in the target tissues to generate biological and hormonal responses. Another paper notes the possibility of a genetic defect in cancer cells that results in the abnormal accumulation of sterol carrier protein (SCP) and cholesterol in vivo; and also in the inability to maintain levels of SCP or cholesterol in vitro. One paper shows that tartrate, or other organic acids, secreted into the medium by the penicillia keeps the pH in an optimal range for acid protease degradation of proteins and glycoproteins. This mechanism helps the fungus to survive in a nutrient environment (which is unbalanced with respect to an optimum C/N ratio and at a pH unfavorable to many bacteria and other life forms). Another paper proposes a model for the modulation of ATP synthetase activities and medium exchange reactions by energy input, substrate concentration, or others that affect the microenvironment of the enzyme under certain conditions. The compendium will prove beneficial to molecular biologists, general biologists, microbiologists, and biochemists.


Cellulose Chemistry And Properties Fibers Nanocelluloses And Advanced Materials

Author by : Orlando J. Rojas
Languange : en
Publisher by : Springer
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Description : Vincent Bulone et al.: Cellulose sources and new understanding of synthesis in plants Thomas Heinze et al.:Cellulose structure and properties Thomas Rosenau, Antje Potthast, Ute Henniges et al.: Recent developments in cellulose aging (degradation / yellowing / chromophore formation) Sunkyu Park et al.:Cellulose crystallinity Lina Zhang et al.:Gelation and dissolution behavior of cellulose Yoshiyuki Nishio et al.:Cellulose and derivatives in liquid crystals Alessandro Gandini, Naceur Belgacem et al.:The surface and in-depth modification of cellulose fibers Emily D. Cranston et al.:Interfacial properties of cellulose Herbert Sixta, Michael Hummel et al.Cellulose Fibers Regenerated from Cellulose Solutions in Ionic Liquids Qi Zhou et al.:Cellulose-based biocomposites Orlando Rojas et al.:Films of cellulose nanocrystals and nanofibrils Pedro Fardim et al.:Functional cellulose particles Wadood Hamad et al.:Cellulose Composites


Enzyme Kinetics Catalysis And Control

Author by : Daniel L. Purich
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 54
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Description : Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. Historical analysis of kinetic principles including advanced enzyme science Provides both theoretical and practical measurements tools Coverage of single molecular kinetics Examination of force generation mechanisms Discussion of organic and inorganic enzyme reactions


Applications Of Physical Methods To Inorganic And Bioinorganic Chemistry

Author by : Robert A. Scott
Languange : en
Publisher by : John Wiley & Sons
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Total Read : 95
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Description : Modern spectroscopic and instrumental techniques are essential tothe practice of inorganic and bioinorganic chemistry. This firstvolume in the new Wiley Encyclopedia of Inorganic ChemistryMethods and Applications Series provides a consistent andcomprehensive description of the practical applicability of a largenumber of techniques to modern problems in inorganic andbioinorganic chemistry. The outcome is a text that providesinvaluable guidance and advice for inorganic and bioinorganicchemists to select appropriate techniques, whilst acting as asource to the understanding of these methods. This volume is also available as part of Encyclopedia ofInorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007to 2010, representing areas of key developments in the field ofinorganic chemistry published in the Encyclopedia of InorganicChemistry. ahref="http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1119994284.html"Findout more/a.


Comprehensive Natural Products Ii

Author by : Anonim
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
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Description : This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content


Chemical And Biochemical Catalysis For Next Generation Biofuels

Author by : Blake A Simmons
Languange : en
Publisher by : Royal Society of Chemistry
Format Available : PDF, ePub, Mobi
Total Read : 28
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Description : The development of renewable and sustainable lignocellulosic biofuels is currently receiving worldwide attention and investment. Despite decades of research, there remain significant challenges to be overcome before these biofuels can be produced in large volumes at competitive prices. One obstacle is the lack of efficient and affordable catalytic systems to dissolve and hydrolyze polysaccharides into sugars. These sugars are then fed to microrganisms and fermented into biofuels. The price of these catalysts, be they biological, thermochemical, or chemical in nature, represent one of the largest costs in the conversion process. There are a number of catalytic schemes, each with their own advantages and disadvantages, available. This book presents a general yet substantial review of the most promising processes and the spectrum of biomass pretreatment, enzymes, chemical catalysts, and hybrid approaches of hydrolyzing biomass into fermentable sugars. It is the only currently available book that compares the biochemical, chemical, and thermochemical conversion processes to biofuel production.


Enzymes Catalysis Kinetics And Mechanisms

Author by : N.S. Punekar
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 9
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Description : This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to plan enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject.


Biomass Biofuels Biochemicals

Author by : Sudhir P. Singh
Languange : en
Publisher by : Elsevier
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Description : Advances in Enzyme Catalysis and Technologies intends to provide the basic structural and functional descriptions, and classification of enzymes. The scientific information related to the recombinant enzyme modifications, discovery of novel enzymes and development of synthetic enzymes are also presented. The translational aspects of enzyme catalysis and bioprocess technologies are illustrated, by emphasizing the current requirements and future perspectives of industrial biotechnology. Several case studies are included on enzymes for biofuels application, micro algal biorefineries, high-value bioactive molecules production and enzymes for environmental processes, such as enzymatic bioprocessing for functional food development, biocatalytic technologies for the production of functional sweetener, etc. Provides a conceptual understanding of enzyme catalysis, enzyme engineering, discovery of novel enzymes, and technology perspectives Includes comprehensive information about the inventions and advancement in enzyme system development for biomass processing and functional food developmental aspects Gives an updated reference for education and understanding of enzyme technology


Atomistic Approaches In Modern Biology

Author by : Markus Reiher
Languange : en
Publisher by : Springer Science & Business Media
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Description : With contributions by numerous experts


Enzyme Kinetics And Mechanism Part F Detection And Characterization Of Enzyme Reaction Intermediates

Author by : Daniel L. Purich
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 77
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File Size : 54,9 Mb
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Description : The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Spectroscopic Detection of Reaction Intermediates Isotopic and Kenetic Detection of Reaction Intermediates Chemical Trapping and Inhibitor Methods for Detecting Reaction Intermediates


Flow Chemistry

Author by : Santiago V Luis
Languange : en
Publisher by : Royal Society of Chemistry
Format Available : PDF, ePub, Mobi
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Description : Historically pharmaceutical and fine chemical products have been synthesised using batch methods, but increasingly chemists are looking towards flow chemistry as a greener and more efficient alternative. In flow chemistry reactions are performed in a reactor with the reactants pumped through it. It has the benefit of being easily scaled up and it is straightforward to integrate synthesis, workup and analysis into one system. Flow chemistry is considered a greener alternative to batch chemistry because it is easier to control and minimise hazardous intermediates and by-products. There is significant interest in the use of flow chemistry both in the lab and on an industrial scale. Flow Chemistry provides an update on recent advances that have been made in the field. Particular emphasis is given to the new integrated approaches that bring together several elements to implement flow processes as a regular green chemistry tool for the chemical industries. With chapter contributions from several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries. om several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries.om several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries.om several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries.


Computational Approaches For Studying Enzyme Mechanism

Author by : Anonim
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 94
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Description : Computational Approaches for Studying Enzyme Mechanism, Part B is the first of two volumes in the Methods in Enzymology series that focuses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of the life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, genetics, and other fields of study. Focuses on computational approaches for studying enzyme mechanism Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in intermediate filament associated proteins, and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers


Chemical And Biochemical Catalysis For Next Generation Biofuels

Author by : Blake A Simmons
Languange : en
Publisher by : Royal Society of Chemistry
Format Available : PDF, ePub, Mobi
Total Read : 78
Total Download : 218
File Size : 51,9 Mb
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Description : The development of renewable and sustainable lignocellulosic biofuels is currently receiving worldwide attention and investment. Despite decades of research, there remain significant challenges to be overcome before these biofuels can be produced in large volumes at competitive prices. One obstacle is the lack of efficient and affordable catalytic systems to dissolve and hydrolyze polysaccharides into sugars. These sugars are then fed to microrganisms and fermented into biofuels. The price of these catalysts, be they biological, thermochemical, or chemical in nature, represent one of the largest costs in the conversion process. There are a number of catalytic schemes, each with their own advantages and disadvantages, available. This book presents a general yet substantial review of the most promising processes and the spectrum of biomass pretreatment, enzymes, chemical catalysts, and hybrid approaches of hydrolyzing biomass into fermentable sugars. It is the only currently available book that compares the biochemical, chemical, and thermochemical conversion processes to biofuel production.


Model Systems In Catalysis

Author by : Robert Rioux
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 19
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Description : This book is an excellent compilation of cutting-edge research in heterogeneous catalysis and related disciplines – surface science, organometallic catalysis, and enzymatic catalysis. In 23 chapters by noted experts, the volume demonstrates varied approaches using model systems and their successes in understanding aspects of heterogeneous catalysis, both metal- and metal oxide-based catalysis in extended single crystal and nanostructured catalytic materials. To truly appreciate the astounding advances of modern heterogeneous catalysis, let us first consider the subject from a historical perspective. Heterogeneous catalysis had its beginnings in England and France with the work of scientists such as Humphrey Davy (1778–1829), Michael Faraday (1791–1867), and Paul Sabatier (1854–1941). Sabatier postulated that surface compounds, si- lar to those familiar in bulk to chemists, were the intermediate species leading to catalytic products. Sabatier proposed, for example, that NiH moieties on a Ni sur- 2 face were able to hydrogenate ethylene, whereas NiH was not. In the USA, Irving Langmuir concluded just the opposite, namely, that chemisorbed surface species are chemically bound to surfaces and are unlike known molecules. These chemisorbed species were the active participants in catalysis. The equilibrium between gas-phase molecules and adsorbed chemisorbed species (yielding an adsorption isotherm) produced a monolayer by simple site-filling kinetics.


New Trends In Enzyme Catalysis And Biomimetic Chemical Reactions

Author by : Gertz I. Likhtenshtein
Languange : en
Publisher by : Springer Science & Business Media
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Description : "This book is a view of enzyme catalysis by a physico-chemist with long-term experience in the investigation of structure and action mechanism of biological catalysts. This book is not intended to provide an exhaustive survey of each topic but rather a discussion of their theoretical and experimental background, and recent developments. The literature of enzyme catalysis is so vast and many scientists have made important contribution in the area, that it is impossible in the space allowed for this book to give a representative set of references. The author has tried to use reviews, and general principles of articles. He apologizes to those he has not been able to include. . [...] The monograph is intended for scientists working on enzyme catalysis and adjacent areas such as chemical modeling of biological processes, homogeneous catalysis, biomedical research and biotechnology. The book can be use as a subsidiary manual for instructors, graduate and undergraduate students of university biochemistry and chemistry departments."--Pages ix-x.


Computational Modeling For Homogeneous And Enzymatic Catalysis

Author by : Keiji Morokuma
Languange : en
Publisher by : John Wiley & Sons
Format Available : PDF, ePub, Mobi
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Description : Here, the world's most active and productive computational scientists from academia and industry present established, effective and powerful tools for understanding catalysts. With its broad scope -- nitrogen fixation, polymerization, C-H bond activation, oxidations, biocatalysis and much more -- this book represents an extensive knowledge base for designing efficient catalysts, allowing readers to improve the performance of their own catalysts.


Enzyme Technologies

Author by : Wu-Kuang Yeh
Languange : en
Publisher by : John Wiley and Sons
Format Available : PDF, ePub, Mobi
Total Read : 66
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Description : An authoritative review of the latest developments in thechemical biology of enzymes In the first decade of the twenty-first century, enzymes andtheir multiple applications have played a critical role in thediscovery and development of many new therapeutic agents.This bookis a coordinated compilation of research expertise and currentopinion uniquely focused on enzymes and their properties andapplications. Compiled by editors with a combined pharmaceutical experience ofover sixty years, the text provides in-depth reviews of recentdevelopments in selective topics on biosynthesis, biocatalysis, andchemical biology of enzymes as it applies to drug discovery,development, and manufacture. The first in a multi-part series on enzymes, this volumefeatures three sections: New Approaches to Find and Modify Enzymes describes the emergingfield of metagenomics, presents the practical applications ofdirected evolution to enzymes and pathways, and explores approachesfor the discovery and design of biocatalysts Biocatalytic Applications reviews specific applications ofdifferent reactions in producing active pharmaceutical ingredientsand surveys recent developments employing enzymes in organicsynthesis Biosynthetic Applications goes over successful drug discoveriesand developments by combinatorial biosynthesis and reviews theapplication of combinatorial biosynthesis among multiple compatiblehosts These timely discussions, which cover everything from chemicalbiology of enzymes, to the redesign of binding and catalyticspecificities of enzymes, make this volume a valuable tool forkeeping up to date. As such, it is an important read forresearchers, students, and professors in the study ofbiotechnology, life sciences, biochemistry, enzymology, medicinalchemistry, and natural products.


Recombinant Enzymes From Basic Science To Commercialization

Author by : Azura Amid
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 58
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Description : This edited work presents studies that clarify the basics of producing recombinant enzymes that finally lead to commercialization. It enables researchers to see what is crucial to the commercialization process, from examining the cloning method, using analytical techniques such as calculating the total protein content and enzyme activity, through considering upstream and downstream processes, to the final product. Readers will discover the importance of the cloning method as it influences the upstream and downstream processes and determines the level of success of the recombinant enzyme commercialization processes. We see that the two main factors that are particularly sensitive during the cloning process are the vector and the host. A discussion of analytical techniques is presented followed by studies on important stages during the upstream processes including the process of optimizing the media to get results and high enzyme activity. Downstream processes such as the cell disruption technique, purification and formulation of the final product are then considered. The reader is introduced to software that helps streamline recombinant enzyme production from the upstream to downstream processes, to facilitate the process of up-scaling production. This work includes a case study as tool, to guide understanding of the commercialization process. The work is written for researchers in the field and is especially suited to those who are under pressure to embark on the tough process of commercialization.


Time Resolved Vibrational Spectroscopy

Author by : George H. Atkinson
Languange : en
Publisher by : Taylor & Francis
Format Available : PDF, ePub, Mobi
Total Read : 79
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Description : First published in 1987. Routledge is an imprint of Taylor & Francis, an informa company.