Comprehensive Cytopathology

A guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and covers the recognized normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. Includes a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Provides updates to crucial chapters to keep you on top of the latest diagnosis and techniques.

This best-selling book provides you with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and covers the recognized normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is lavishly illustrated, making it the perfect practical resource for daily reference in the laboratory. Provides an accessible guide to diagnostic investigation and screening. Includes a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Utilizes a consistent chapter structure to make finding the answers you need quick and easy. Provides updates to crucial chapters to keep you on top of the latest diagnosis and techniques. Incorporates differential diagnosis tables for easy comparison/contrast of diagnoses. Offers more than 1800 full-color images depicting a full range of normal and abnormal findings. Discusses new concepts on molecular basis of neoplasia. Explores the role of cytogenetics in cancer development.

In recent decades, cytopathology has assumed an increasing role in the primary diagnosis of mass lesions owing to its ability to deliver rapid, non-invasive, and timely information. This book provides a comprehensive overview of the role of cytology at various body sites. The diagnostic details covered are abbreviated in comparison with those in pathology texts. Instead, a more clinical approach is taken, with the focus on the advantages and limitations of techniques and the key features of entities that are important to clinicians. Pathological–clinical correlation is highlighted throughout the book, ensuring that it will be highly relevant for clinicians. In particular, physicians who deal with oncology patients will find it to be a rich source of guidance on how to use and understand cytopathology in the diagnosis and exclusion of malignancy.

This new edition examines the latest diagnostic techniques for the interpretation of a complete range of cytological specimens. It is concise, yet covers all of the organ systems in which the procedure is used, with the number of pages devoted to each body site proportional to the clinical relevance of cytology for that site. Inside, you'll find new information on ductal lavage cytology and expanded coverage of FNA performance, keeping you current with the newest procedures. Over 700 full-color illustrations provide you with a real-life perspective of a full range of cytologic findings. Each chapter includes a discussion of indications and methods, along with a section on differential diagnosis accompanied by ancillary diagnostic techniques such as immunohistochemistry and molecular biology, where appropriate. As an Expert Consult title, it includes online access to the complete text of the book, fully searchable-as well as all of the images downloadable for your personal use-at www.expertconsult.com. We like this book and use it frequently, thank you Dr Cibas Reviewed by: PathLab.org Date: June 2014 Offers comprehensive coverage of everyday diagnostic work in a concise format for a practical benchside manual. Covers every type of cytology-gynecology, non-gynecology, and FNA. Presents an in-depth differential diagnosis discussion for all major entities. Examines the role of special techniques such as immunohistochemistry, flow cytometry, and molecular biology in resolving difficulties in interpretation and diagnosis. Provides an in-depth analysis of common diagnostic pitfalls to assist with daily signing out and reporting. Features coverage of patient management in discussions of pertinent clinical features. Uses capsule summaries featuring easy-to-read bulleted text that provide a quick review of key differential diagnoses, diagnostic pitfalls, cytomorphologic features, and tissue acquisition protocols for specific entities. Includes over 700 full-color illustrations that provide you with a real-life perspective of a full range of cytologic findings. Features anytime, anywhere online access to the complete text of the book, fully searchable-as well as all of the images downloadable for your personal use-at www.expertconsult.com. Covers automated cytology and HPV testing in Cervical and Vaginal Cytology chapter, providing an up-to-date reference on the techniques used in today's labs. Offers new information on ductal lavage cytology and expanded coverage of FNA performance, keeping you current with the newest procedures. Discusses the implementation of proficiency testing and changes in laboratory inspection and accreditation. Includes recommendations from the 2008 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

This outstanding monograph presents a detailed description of cytopathological lesions of the female genital tract. Twelve international experts in the cytopathology of glandular lesions cover the complete spectrum of this challenging subject. Genital glandular lesions, both benign and malignant, are an appealing field of cytopathology. Malignant lesions of the endocervix and endometrium are becoming more common all over the world, compared to squamous cell carcinoma. In situ and invasive endocervical adenocarcinoma, endometrial adenocarcinoma and endometrial hyperplasias are presented in this book. Additionally ovarian lesions focusing data obtained from detailed intraoperative studies and other areas of the genital tract, such as the vulva and fallopian tube, which are less known and thus have seen fewer publications, are also shown. The impact of the Bethesda System, as well as basic and ancillary techniques in the study of glandular lesions complete the monograph. This book will be of great use to cytopathologists, pathologists and cytotechnologists and to students of these specialities as it deals with the most common areas of their daily work.

This book provides a comprehensive, practical, and state-of-the art review addressing the major issues and challenges in cytopathology practice using a question and answer format. Making an accurate diagnosis, especially on a limited cytology sample obtained by minimally invasive procedures, is often challenging, yet crucial to patient care. Using the most current and evidence-based approaches, this book: 1) focuses on frequently asked questions in day-to-day practice of cytopathology as well as surgical pathology; 2) provides quick, accurate, and useful answers; 3) emphasizes the importance of clinical, radiological, and cytological correlation, as well as cyto-histological correlation; and 4) delineates how to judiciously use immunohistochemistry, molecular tests, flow cytometry, cytogenetics, and other established ancillary studies including next generation sequencing and computer-assisted diagnostics. Chapters are written by experts in their fields and provide the most up-to-date information in the field of cytopathology. Practical Cytopathology: Frequently Asked Questions serves as a practical resource and guide to relevant references for trainees, cytotechnologists, and cytopathologists at various skill levels.

The primary thrust of this atlas is a comparison between different diagnostic entities with cytologic findings summarized in tabulated forms. The book contains over 3,200 full color photographs that illustrate the criteria for the cytology described. The Color Atlas of Differential Diagnosis in Exfoliative and Aspiration Cytopathology is an excellent reference for everyday use when difficult and challenging cases face both cytotechnologists and pathologists. A tabulated form of information saves valuable time while reporting cytopathology.

This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care

This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004. Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a “must have” for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.

Color Atlas of Pulmonary Cytopathology is the only text to include, under one cover, up-to-date information on every aspect of Respiratory Cytopathology. The atlas includes techniques of bronchoscopy, brochoalveolar lavage, and fine needle aspiration biopsy, a detailed section on cytopreparatory techniques, liberal use of images on histomorphology to complement cytology, emphasis on diagnostic pitfalls, a detailed section on cytopathology of non-neoplastic conditions, and much more. Abundantly illustrated with over 1300 color images, the atlas presents not only the usual cytohistologic patterns of various disease entities, but also focuses on differential diagnostic problems and depicts the differentiating features.

The new edition of Diagnostic Cytopathology provides the practicing and trainee cytopathologist with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book covers normal and abnormal cytological findings encountered in all body sites where cytological applications are used. Appropriate histopathological, immunohistochemical and molecular correlations, together with a consideration of the possible differential diagnoses, accompany the cytological findings. The reader can see a full range of normal and abnormal findings with almost 2,000 full-colour images. The book is heavily referenced to ensure that it will serve as a practical resource for daily reference in the laboratory. A uniformity of basic chapter structure will help readers to quickly find the diagnostic answers they seek. This edition stresses not just the diagnostic cytological features of the various conditions encountered, but also the diagnostic pitfalls and the grey areas between so as to enable the reader to give more evidence-based reports. In recognition of their rapid expansion, there are new chapters on recent technological developments and on the cytodiagnosis of childhood tumours. A special section on the importance of multidisciplinary team meetings that include the cytopathologist as a core member of the team has also been included at the end of each chapter. As active members of this team, cytopathologists can define their role in the management pathway and thus bring the patient and the microscope together as never before. The full text can be accessed online and images downloaded via Expert Consult.

Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation, pathology, differential diagnosis, and prognosis for each disorder-promoting clear communication between pathologists and surgeons. Written by more than 30 internationally distinguished physicians, Surgical Pathology of the Head and Neck, Second Edition now contains: over 1045 photographs, micrographs, drawings, and tables-nearly 200 more illustrations than the first edition five new chapters on molecular biology, fine-needle aspiration, vesiculobullous diseases, neck dissections, and radiation a cumulative and expanded index in each volume Unparalleled in scope and content by any other book available on the subject, Surgical Pathology of the Head and Neck, Second Edition is a must-have resource for oral, surgical, and general pathologists; otolaryngologists; oral, maxillofacial, plastic and reconstructive, general, head and neck, and orthopedic surgeons and neurosurgeons; oncologists; hematologists; ophthalmologists; radiologists; endocrinologists; dermatologists; dentists; and residents and fellows in these disciplines.

This manual for diagnostic cytologists offers detailed guidance on diagnostic problems likely to be encountered in everyday practice. It encompasses exfoliative and aspiration cytology of all major nongynecologic body sites. Each chapter opens with an algorithm that presents the reader with the relevant microscopic findings, the most important additional findings, and the differential diagnostic possibilities and problems in a clear and easily remembered form. Another important feature is the wealth of high-quality color photomicrographs, which clearly document the visual appearances of the most important lesions and highlight the differential diagnostic difficulties. The accompanying text contains helpful general remarks and presents further relevant information on diagnostics, differential diagnostic procedures, and auxiliary methods. Besides established cytologists and pathologists, cytopathologists in training and cytotechnologists will find this book to be a valuable aid.

This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology

This edition stresses not just the diagnostic cytological features of the various conditions encountered, but also the diagnostic pitfalls and the grey areas between so as to enable the reader to give more evidence-based reports. In recognition of their rapid expansion, there are new chapters on recent technological developments and on the cytodiagnosis of childhood tumours. A special section on the importance of multidisciplinary team meetings that include the cytopathologist as a core member of the team has also been included at the end of each chapter. As active members of this team, cytopathologists can define their role in the management pathway and thus bring the patient and the microscope together as never before. The full text can be accessed online and images downloaded via Expert Consult.

This book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader to benefit from their experiences by providing a valuable tool for the implementation of these techniques in daily practice. Though the use of molecular techniques is well established in surgical biopsies, to date they are not widely used in connection with cytological material. However, in some fields like lung cancer or aspirates from the pancreas and biliary tract the only available material for diagnosis is the cytological preparation a fact that has created a need for the standardization of molecular techniques on cytology.

Gynecological and Breast Cytopathology Board Review and Self-Assessment is a comprehensive systems-based review of gynecological and breast cytology including cytomorphology, pitfalls and ancillary studies. Presented in a high-yield format with board-type multiple choice questions and detailed answers, this review includes chapters covering Pap smear cytology, colposcopy, breast FNA, and Pelvic washings. The book is also enriched with features to maximize studying and reviewing of cytopathology, including high-yield review with tables emphasizing key points, board exam-type questions, and high quality full-color images. Written by cytologists and cytopathologists with experience in the practice of modern cytology, as well as intensive teaching experience at national and international levels. Gynecological and Breast Cytopathology Board Review and Self-Assessment provides an excellent review, resource, and self-assessment for pathologists, cytopathologists, cytotechnologists, and trainees preparing for board examinations.

A distinguished panel of experts concisely interprets recent diagnostic advances in classic pathology to produce a readily accessible guide that helps the practicing pathologist achieve accurate everyday diagnoses. Arranging the important diagnostic features of the most common diseases and tumors by organ systems, this book provides for each disease the pertinent clinical information, its salient diagnostic features, relevant ancillary data (e.g., immunohistochemical profiles), the main differential diagnoses, and the latest tumor staging information, thus ensuring easy access to all the information essential for case sign-out. Authoritative and richly detailed, Essentials of Anatomic Pathology concisely summarizes all the critical information every pathologist needs today to recognize, understand, and accurately interpret both gross and light microscopic findings in anatomic pathology specimens.

Concise yet comprehensive, Cytology: Diagnostic Principles and Clinical Correlates is a practical guide to the diagnostic interpretation of virtually any cytological specimen you may encounter. This highly useful bench manual covers all organ systems and situations in which cytology is used, including gynecologic, non-gynecologic, and FNA samples, with an in-depth differential diagnosis discussion for all major entities. As with previous editions, the revised 5th Edition focuses on practical issues in diagnosis and the use of cytology in clinical care, making it ideal for both trainee and practicing pathologists. Uses easy-to-read, bulleted text to provide a quick review of key differential diagnoses, indications and methods, cytomorphologic features, clinical pearls, and tissue acquisition protocols for specific entities. Includes coverage of patient management in discussions of pertinent clinical features and emphasizes clinical correlation throughout. Examines the role of immunohistochemistry, flow cytometry, and molecular biology in resolving difficulties in interpretation and diagnosis. Features more than 550 full-color illustrations that provide a real-life perspective of a full range of cytologic findings. Discusses hot topics such as new diagnostic biomarkers and their utility in differential diagnosis, the latest Bethesda System classifications/terminology, new techniques, and new adjunct tests. Provides an in-depth analysis of common diagnostic pitfalls to assist with daily sign-out and reporting. Includes a video on how to perform fine needle aspiration biopsy, from the patient interview and precautions to demonstration of techniques.