Degradation Rate of Bioresorbable Materials

Degradation Rate of Bioresorbable Materials
Author: F J Buchanan
Publsiher: Elsevier
Total Pages: 424
Release: 2008-09-26
ISBN: 1845695038
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Degradation Rate of Bioresorbable Materials Book Excerpt:

Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials. Part one provides an introductory review of bioresorbable materials and the biological environment of the body. Chapters in Part two address degradation mechanisms of commonly used materials such as polymers and ceramics. This is followed by chapters on bioresorption test methods and modelling techniques in Part three. Part four discusses factors influencing bioresorbability such as sterilisation, porosity and host response. The final section reviews current clinical applications of bioresorbable materials. With its distinguished editor and multidisciplinary team of international contributors, Degradation rate of bioresorbable materials: prediction and evaluation provides a unique and valuable reference for biomaterials scientists, engineers and students as well as the medical community. Comprehensively reviews the most pertinent techniques in safely predicting and evaluating the degradation rate of bioresorbable materials Addresses degradation mechanisms of commonly used materials Discusses factors influencing bioresorbability such as sterilisation and host response

Modelling Degradation of Bioresorbable Polymeric Medical Devices

Modelling Degradation of Bioresorbable Polymeric Medical Devices
Author: J Pan
Publsiher: Elsevier
Total Pages: 260
Release: 2014-10-24
ISBN: 1782420258
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Modelling Degradation of Bioresorbable Polymeric Medical Devices Book Excerpt:

The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed. Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Synthetic Bioabsorbable Polymers for Implants

Synthetic Bioabsorbable Polymers for Implants
Author: Chandra Mauli Agrawal,Jack E. Parr,Steve T. Lin
Publsiher: ASTM International
Total Pages: 167
Release: 2000
ISBN: 0803128703
Category: Medical
Language: EN, FR, DE, ES & NL

Synthetic Bioabsorbable Polymers for Implants Book Excerpt:

From a November 1999 symposium in Kansas City, Missouri, 12 papers explore aspects of biological implants that are absorbed by the body over time from the perspective of materials science. Their topics include the mechanical evaluation of 70:30 poly bone screws after in-vitro degradation, novel biod

Handbook of Biodegradable Polymers

Handbook of Biodegradable Polymers
Author: Catia Bastioli
Publsiher: Walter de Gruyter GmbH & Co KG
Total Pages: 572
Release: 2020-03-09
ISBN: 1501511963
Category: Science
Language: EN, FR, DE, ES & NL

Handbook of Biodegradable Polymers Book Excerpt:

This handbook covers characteristics, processability and application areas of biodegradable polymers, with key polymer family groups discussed. It explores the role of biodegradable polymers in different waste management practices including anaerobic digestion, and considers topics such as the different types of biorefineries for renewable monomers used in producing the building blocks for biodegradable polymers.

Virtual and Rapid Manufacturing

Virtual and Rapid Manufacturing
Author: Ljubomir Tanchev
Publsiher: CRC Press
Total Pages: 866
Release: 2007-09-17
ISBN: 0203931874
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Virtual and Rapid Manufacturing Book Excerpt:

Collection of 120 peer-reviewed papers that were presented at the 3rd International Conference on Advanced Research in Virtual and Rapid Prototyping, held in Leiria, Portugal in September 2007. Essential reading for all those working on V&RP, focused on inducing increased collaboration between industry and academia. In addition to key

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers
Author: Xiang Cheng Zhang
Publsiher: Woodhead Publishing
Total Pages: 476
Release: 2016-09-22
ISBN: 0081003935
Category: Medical
Language: EN, FR, DE, ES & NL

Science and Principles of Biodegradable and Bioresorbable Medical Polymers Book Excerpt:

Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Degradation of Poly lactide based Biodegradable Materials

Degradation of Poly  lactide   based Biodegradable Materials
Author: Hideto Tsuji
Publsiher: Nova Science Pub Incorporated
Total Pages: 76
Release: 2008-01-01
ISBN: 9781604565027
Category: Science
Language: EN, FR, DE, ES & NL

Degradation of Poly lactide based Biodegradable Materials Book Excerpt:

Poly (lactide), i.e., poly (lactic acid) (PLA) is a biodegradable polyester produced from renewable resources. Due to its high mechanical performance and very low toxicity, PLA is utilised for biomedical, pharmaceutical, ecological, industrial, and commodity applications. PLA is susceptible to various types of degradation, such as hydrolytic degradation in the human body and the environment, biodegradation and photodegradation in the environment, and thermal degradation during processing. In biomedical and pharmaceutical applications, the hydrolytic degradation mechanism and rate are crucial factors for determining its performance. In contrast, in most of the environmental, industrial, and commodity applications, an accurate adjustment of the degradation rate as accurate as in biomedical and pharmaceutical applications is not required, or degradation during use can cause a reduction in material performance. However, for recycling PLA to its monomers, information on the mechanism and rate of hydrolytic degradation and thermal degradation at elevated temperatures is indispensable. This book deals with the hydrolytic degradation, biodegradation, thermal degradation, and photodegradation of PLA-based materials with different material factors and degradation conditions or environments.

Bioresorbable Materials and Their Application in Electronics

Bioresorbable Materials and Their Application in Electronics
Author: Xian Huang
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2017-11-16
ISBN: 1108314007
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Bioresorbable Materials and Their Application in Electronics Book Excerpt:

Bioresorbable electronics that can dissolve away in aqueous environments and generate biologically safe products offer a revolutionary solution to replace the built-to-last electronics predominantly used in implanted devices and electronic gadgets. Their use can reduce the risk of surgical complications by minimizing the number of necessary surgeries, and prevent production of electronic waste by allowing rapid device recycling. This Element presents bioresorbable materials such as metals, polymers, inorganic compounds, and semiconductors that have been used to construct electronic devices, and analyzes their unique dissolution behaviors and biological effects. These materials are combined to yield representative devices including passive and active components and functional systems.

Biomedical Hydrogels

Biomedical Hydrogels
Author: Steve Rimmer
Publsiher: Elsevier
Total Pages: 288
Release: 2011-02-26
ISBN: 0857091387
Category: Medical
Language: EN, FR, DE, ES & NL

Biomedical Hydrogels Book Excerpt:

Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel’s interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians. Examines the diverse range and use of hydrogels, focusing on processing methods and novel applications Comprehensive book explores the structure and properties of hydrogels and different fabrication technologies Covers important areas such as processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products

Degradable Polymers

Degradable Polymers
Author: G. Scott,D. Gilead
Publsiher: Springer Science & Business Media
Total Pages: 271
Release: 2012-12-06
ISBN: 9401105715
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Degradable Polymers Book Excerpt:

Few scientific developments in recent years have captured the popular imagination like the subject of'biodegradable' plastics. The reasons for this are complex and lie deep in the human subconscious. Discarded plastics are an intrusion on the sea shore and in the countryside. The fact that nature's litter abounds in the sea and on land is acceptable because it is biodegradable - even though it may take many years to be bioassimilated into the ecosystem. Plastics litter is not seen to be biodegradable and is aesthetically unacceptable because it does not blend into the natural environment. To the environmentally aware but often scientifically naive, biodegradation is seen to be the ecologically acceptable solution to the problem of plastic packaging waste and litter and some packaging manufacturers have exploited the 'green' consumer with exaggerated claims to 'environmentally friendly' biodegradable packaging materials. The principles underlying environmental degradation are not understood even by some manufacturers of 'biodegradable' materials and the claims made for them have been categorized as 'deceptive' by USA legislative authorities. This has set back the acceptance of plastics with controlled biodegradability as part of the overall waste and litter control strategy. At the opposite end of the commercial spectrum, the polymer manufactur ing industries, through their trade associations, have been at pains to discount the role of degradable materials in waste and litter management. This negative campaign has concentrated on the supposed incompatibility of degradable plastics with aspects of waste management strategy, notably materials recycling.

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites
Author: Ismael Moreno-Gomez
Publsiher: Springer
Total Pages: 325
Release: 2019-04-05
ISBN: 3030049906
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites Book Excerpt:

This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.

Durability and Reliability of Medical Polymers

Durability and Reliability of Medical Polymers
Author: Mike Jenkins,Artemis Stamboulis
Publsiher: Elsevier
Total Pages: 296
Release: 2012-08-13
ISBN: 0857096516
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Durability and Reliability of Medical Polymers Book Excerpt:

Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers. Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices. With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians. Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymers Discusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymers Explores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body

Biomedical Composites

Biomedical Composites
Author: Luigi Ambrosio
Publsiher: Elsevier
Total Pages: 648
Release: 2009-11-23
ISBN: 1845697375
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Biomedical Composites Book Excerpt:

Biocomposites are widely used in the medical industry to repair and restore bone, tooth, cartilage skin and other tissues. Biomedical composites, provides a thorough review of the current status, recent progress and future trends in composites for biomedical applications. Part one discusses the fundamentals of biocomposites with chapters on natural composites, design and fabrication of biocomposites, and hard and soft tissue applications of biocomposites. Part two then reviews applications of biocomposites. Chapters discuss composites for bone repair, composite coatings for implants, composites for spinal implants, injectable composites and composites for tissue engineered scaffolds. Chapters in part three discuss the biocompatibility, mechanical behaviour and failure of biocomposites with such topics as cellular response, testing of biocomposites and tribology of biocomposites. Finally part four reviews the future for biocomposites with chapters on nano-structured biocomposites, developing biocomposites as scaffolds and biocomposites in tissue engineering and regenerative medicine. With its distinguished editor and team of international contributors, Biomedical composites is an essential reference to materials scientists and researchers in industry and academia, as well as all those concerned with this increasingly important field. Provides a thorough review of the current status, recent progress and future trends in composites for biomedical applications Discusses the fundamentals of biocomposites with chapters on natural composites, design and fabrication of biocomposites and their applications Chapters address composites for bone repair, spinal implants and various other applications and discuss biocompatability, mechanical behaviour and failure of biocomposites

Biomaterials and Regenerative Medicine in Ophthalmology

Biomaterials and Regenerative Medicine in Ophthalmology
Author: Traian Chirila,Damien Harkin
Publsiher: Elsevier
Total Pages: 560
Release: 2009-12-18
ISBN: 184569743X
Category: Medical
Language: EN, FR, DE, ES & NL

Biomaterials and Regenerative Medicine in Ophthalmology Book Excerpt:

With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field. Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction. With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology. Reviews the increasingly important role of biomaterials and regenerative medicine in the advancement of ophthalmology and optometry Provides an overview of the present status and future direction of biomaterials and regenerative medicine in this important field Discusses applications in both the anterior and prosterior segments of the eye with chapters on such topics as synthetic corneal implants and retinal repair and regeneration

Surface Modification of Biomaterials

Surface Modification of Biomaterials
Author: Rachel Williams
Publsiher: Elsevier
Total Pages: 432
Release: 2010-11-25
ISBN: 0857090763
Category: Medical
Language: EN, FR, DE, ES & NL

Surface Modification of Biomaterials Book Excerpt:

The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material’s surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance. Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone. The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification. Reviews both established surface modifications and those still in the early stages of research and how they can be used to optimise biological interactions and enhance clinical performance Studies analytical techniques and applications of surface modification with chapters assessing biomaterial surface chemistry, surface structure, morphology and topography Discusses modifying biomaterial surfaces to optimise interactions with blood and soft tissues and also to repair and regenerate nerve cells and control infection

Drug Device Combination Products

Drug Device Combination Products
Author: Andrew Lewis
Publsiher: Elsevier
Total Pages: 560
Release: 2009-12-15
ISBN: 1845697480
Category: Medical
Language: EN, FR, DE, ES & NL

Drug Device Combination Products Book Excerpt:

Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development. Advanced drug delivery devices can offer significant advantages over conventional drugs and devices alone, such as increased efficiency, improved performance and convenience. The purpose of this book is to illustrate how effective drug delivery can be achieved by means other than tablets. The book will provide a thorough analysis of the fundamentals, applications and new technologies of drug-device combination products for use throughout the human body. Part one provides readers with an introduction and background to the field. Chapters in Part two discuss areas of application such as catheter based products, drug eluting stents and beads and anti-biotic loaded cements. Part three covers the development of drug device combination products with chapters on such topics as pre-clinical testing, sterilisation, patent issues and regulation of drug device combination products. With its distinguished editor and team of international contributors, Drug-device combination products: delivery technologies and applications is an invaluable reference for product development specialists, materials scientists and engineers in the biomedical industry and academia as well as those concerned with drug delivery. Illustrates how effective drug delivery can be achieved by means other than tablets providing readers with a comprehensive introduction and background to the field Provides a thorough analysis of the fundamentals, applications and new technologies of drug device combination products Discusses areas of application such as catheter based products and reviews the development of drug device combination products including pre-clinical testing and sterilisation

Biodegradable Polymers in Pharmacy and Medicine Classification Chemical Structure Principles of Biodegradation and Use

Biodegradable Polymers in Pharmacy and Medicine  Classification  Chemical Structure  Principles of Biodegradation and Use
Author: Jan Gajdziok,Roman Goněc,David Vetchý
Publsiher: GRIN Verlag
Total Pages: 110
Release: 2016-09-13
ISBN: 3668297754
Category: Medical
Language: EN, FR, DE, ES & NL

Biodegradable Polymers in Pharmacy and Medicine Classification Chemical Structure Principles of Biodegradation and Use Book Excerpt:

Document from the year 2016 in the subject Medicine - Pharmacology, , course: Pharmaceutical technology, language: English, abstract: The aim of this book is to provide a brief but comprehensive overview on the issue of biodegradable polymers. The introduction chapter is followed by a description of the general characteristics of biodegradable polymers and pathways of their degradation in the human body. Particular pitfalls and specifics of their various biomedical and pharmaceutical applications, especially in the field of pharmaceutical technology, are described in order to define the ideal carrier polymer system for specific types of therapy. Finally, the work presents the classification of these polymers based on the type of degradation mechanism. This section also includes the chemical structure of particular polymer molecules, their chemical or bio-synthesis and the description of their uses in specific biomedical and pharmaceutical applications. The book could be used as a textbook for students of medical and pharmaceutical sciences as well as by researchers in this field or industrial area. In the past few decades, biodegradable polymers have reached significant importance in fields of biomedical and pharmaceutical applications. They have become preferred candidates for the manufacture of therapeutic forms, for instance, orthopaedics devices, temporary bone screws and spins, three-dimensional scaffolds for tissue engineering or drug delivery systems for sustained and targeted release. Each of these applications requires material with specific physical, biological, and chemical properties, as well as specific degradation profile. These polymers (natural or synthetic) undergo hydrolytic or enzymatic degradation, which both have some advantages and disadvantages. Most widely used polymer materials in biomedical applications are listed, including their structure and degradation pathways.

Biodegradable Metals

Biodegradable Metals
Author: Hendra Hermawan
Publsiher: Springer Science & Business Media
Total Pages: 69
Release: 2012-07-15
ISBN: 3642311709
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Biodegradable Metals Book Excerpt:

This book in the emerging research field of biomaterials covers biodegradable metals for biomedical applications. The book contains two main parts where each of them consists of three chapters. The first part introduces the readers to the field of metallic biomaterials, exposes the state of the art of biodegradable metals, and reveals its application for cardiovascular implants. Some fundamental aspects to give basic understanding on metals for further review on the degradable ones is covered in chapter one. The second chapter introduces the concept of biodegradable metals, it's state of the art and discuses a shifted paradigm from inert to bioactive, from corrosion resistant to corrodible metals. The third chapter focuses on the challenges and opportunities of using biodegradable metals for cardiovascular applications. The second part exposes an example of biodegradable metals from its concept to applications where a complete study on metallic biodegradable stent is detailed from materials design, development, testing till the implant fabrication. The forth chapter reveals new alloys development devoted for metallic biodegradable stent based on required criteria derrived from clinical needs and current nondegradable stents properties. Degradation of the alloys in simulated arterial conditions and its effect to cells are exposed in chapter five. The both chapters are concluded with a benchmarking of some more recent researches on materials development and testing for biodegradable stents. Chapter six reveals the tranformation process of the materials into stent prototypes where a standard process for making 316L stainless steel stents was followed. The book is completed by a perspective on the use of biodegradable metals for biomedical applications in the era of tissue engineering.

Materials for Biomedical Engineering Absorbable Polymers

Materials for Biomedical Engineering  Absorbable Polymers
Author: Alexandru Grumezescu,Valentina Grumezescu
Publsiher: Elsevier
Total Pages: 462
Release: 2019-06-28
ISBN: 0128184167
Category: Medical
Language: EN, FR, DE, ES & NL

Materials for Biomedical Engineering Absorbable Polymers Book Excerpt:

Materials for Biomedical Engineering: Absorbable Polymers provides a detailed and comprehensive review of recent progress in absorbable biopolymers and their impact on biomedical engineering. The book's main focus lies in their classification, processing, properties and performance, biocompatibility, and their applications in tissue engineering, drug delivery, bone repair and regenerative medicine. The most up-to-date methods used to obtain such polymers and how to improve their properties is discussed in detail. This book provides readers with a comprehensive and updated review of the latest research in the field of absorbable polymers for biomedical applications. Provides knowledge of the range of absorbable polymers currently available, enabling the reader to make optimal materials selection decisions Presents detailed information on current and proposed applications of the latest developments Includes a strong emphasis on chemistry and physico-chemical characterization of these materials and their application in biomedical engineering

Bioresorbable Polymers and their Biomedical Applications

Bioresorbable Polymers and their Biomedical Applications
Author: Declan M Devine
Publsiher: Smithers Rapra
Total Pages: 242
Release: 2017-04-10
ISBN: 1911088092
Category: Science
Language: EN, FR, DE, ES & NL

Bioresorbable Polymers and their Biomedical Applications Book Excerpt:

Bioresorbable or biodegradable polymers are commonly used in various biomedical applications. The application of bioresorbable polymers in the biomedical sector has been widely exploited by immobilising suturing thread with an analgesic or antibacterial drugs, and the development of bioresorbable vascular scaffolds, wound-healing and intravenous drug-delivery devices. Furthermore, biodegradable polymers have been investigated as a replacement for metallic orthopaedic devices due to their precise control of material composition and microstructure. These polymers are eliminated from the body via dissolution, assimilation and excretion through metabolic pathways. The hydrolysing process breaks down the polymer into smaller units and its degradation products are excreted by means of the citric acid cycle or by direct renal excretion with no residual side effects.Processing of bioresorbable implants can be achieved via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. However, special consideration must be given when processing these materials because heat can cause a reduction in molecular weight due to the hydrolysing of bonds. In addition, overheating can depolymerise the polymer and, as a result, monomers can have a plasticising effect on the polymer. Recently, alternative approaches utilising rapid prototyping and micro-/nanofabrication processes have been employed.This book addresses these issues and highlights recent advances in the biomedical field that have being enabled by the use of biodegradable polymers. This book is designed as a reference guide for academic researchers utilising biodegradable polymers in a range of areas from tissue engineering to controlled release of active pharmaceuticals, through to industry-based processors of biodegradable polymers.