Discover Biology

Discover Biology
Author: Anu Singh-Cundy,Gary Shin
Publsiher: W. W. Norton
Total Pages: 550
Release: 2017-06
ISBN: 9780393644265
Category: Science
Language: EN, FR, DE, ES & NL

Discover Biology Book Excerpt:

Developing scientific literacy through active learning--before, during, and after class.

Textbook of Drug Design and Discovery Fifth Edition

Textbook of Drug Design and Discovery  Fifth Edition
Author: Kristian Stromgaard,Povl Krogsgaard-Larsen,Ulf Madsen
Publsiher: CRC Press
Total Pages: 579
Release: 2016-08-19
ISBN: 1315354543
Category: Medical
Language: EN, FR, DE, ES & NL

Textbook of Drug Design and Discovery Fifth Edition Book Excerpt:

Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects. Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery. The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding). The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.

Structural Biology in Drug Discovery

Structural Biology in Drug Discovery
Author: Jean-Paul Renaud
Publsiher: John Wiley & Sons
Total Pages: 706
Release: 2020-02-05
ISBN: 1118681010
Category: Medical
Language: EN, FR, DE, ES & NL

Structural Biology in Drug Discovery Book Excerpt:

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins

Systems Biology in Drug Discovery and Development

Systems Biology in Drug Discovery and Development
Author: Daniel L. Young,Seth Michelson
Publsiher: John Wiley & Sons
Total Pages: 398
Release: 2011-10-18
ISBN: 0470261234
Category: Medical
Language: EN, FR, DE, ES & NL

Systems Biology in Drug Discovery and Development Book Excerpt:

The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent that integration, inform the drug research processes that are most relevant to the pharmaceutical and biotechnology industries. The first book to focus on comprehensive systems biology and its applications in drug discovery and development, it offers comprehensive and multidisciplinary coverage of all phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design and execution, as well as the complementary systems approaches that make these processes more efficient. It also provides models for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker identification. Introducing and explaining key methods and technical approaches to the use of comprehensive systems biology on drug development, the book addresses the challenges currently facing the pharmaceutical industry. As a result, it is essential reading for pharmaceutical and biotech scientists, pharmacologists, computational modelers, bioinformaticians, and graduate students in systems biology, pharmaceutical science, and other related fields.

Using The Biological Literature

Using The Biological Literature
Author: Diane Schmidt,Elisabeth B. Davis
Publsiher: CRC Press
Total Pages: 484
Release: 2001-12-06
ISBN: 0824741714
Category: Language Arts & Disciplines
Language: EN, FR, DE, ES & NL

Using The Biological Literature Book Excerpt:

"Provides an in-depth review of current print and electronic tools for research in numerous disciplines of biology, including dictionaries and encyclopedias, method guides, handbooks, on-line directories, and periodicals. Directs readers to an associated Web page that maintains the URLs and annotations of all major Inernet resources discussed in th

Essays in Animal Behaviour

Essays in Animal Behaviour
Author: Jeffrey R Lucas,Leigh W. Simmons
Publsiher: Elsevier
Total Pages: 384
Release: 2005-11-07
ISBN: 9780080494821
Category: Nature
Language: EN, FR, DE, ES & NL

Essays in Animal Behaviour Book Excerpt:

Recently, the 50th anniversary of the publication of Animal Behaviour has passed. To mark the occasion, a group of prominent behaviourists have written essays relevant to their fields. These essays provide a glimpse of the study of behaviour looking in all directions. History and future aside, it is imperative to broadcast this information from the perspective of the behaviourists who have helped shape both the past and the future. It is important for any field to be both retrospective and prospective: where have we been, where are we going, where are we now? These essays provide a unique personal reflection on the history of animal behaviour from John Alcock, Stuart and Jeanne Altmann, Steve Arnold, Geoff Parker, and Felicity Huntingford. Six topics are reflected on and include: The History of Animal Behavioural Research, Proximate Mechanisms, Development, Adaptation, and Animal Welfare. Broad range of essays on animal behaviour Written by leaders in the field Offers a history of the study of behaviour plus essays on the future of behavioural studies Contains over 30 full color illustrations Includes essays on development, mechanisms and adaptive significance of behaviour

ENC Focus

ENC Focus
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1994
ISBN: 1928374650XXX
Category: Mathematics
Language: EN, FR, DE, ES & NL

ENC Focus Book Excerpt:

CD ROMs and Laserdiscs for Science

CD ROMs and Laserdiscs for Science
Author: Anonim
Publsiher: Unknown
Total Pages: 32
Release: 1997
ISBN: 1928374650XXX
Category: Mathematics
Language: EN, FR, DE, ES & NL

CD ROMs and Laserdiscs for Science Book Excerpt:

The Taste for Ethics

The Taste for Ethics
Author: Christian Coff
Publsiher: Springer Science & Business Media
Total Pages: 212
Release: 2006-06-27
ISBN: 1402045549
Category: Philosophy
Language: EN, FR, DE, ES & NL

The Taste for Ethics Book Excerpt:

This book marks a new departure in ethics, which has up to now been a question of ‘the good life’ in relation to other people, based on Greek concepts of friendship and the Judaeo-Christian ‚caritas.’ No early moral teaching discussed man’s relation to the origin of foodstuffs and the system that produced them; doubtless the question was of little interest since the production path was so short.

Textbook of Drug Design and Discovery

Textbook of Drug Design and Discovery
Author: Kristian Stromgaard,Povl Krogsgaard-Larsen,Ulf Madsen
Publsiher: CRC Press
Total Pages: 478
Release: 2009-10-07
ISBN: 1439882401
Category: Medical
Language: EN, FR, DE, ES & NL

Textbook of Drug Design and Discovery Book Excerpt:

The molecular biological revolution and the mapping of the human genome continue to provide new challenges and opportunities for drug research and design. Future medicinal chemists and drug designers must have a firm background in a number of related scientific disciplines in order to understand the conversion of new insight into lead structures an

Reclaiming Science from Darwinism

Reclaiming Science from Darwinism
Author: Kenneth Poppe
Publsiher: Harvest House Publishers
Total Pages: 320
Release: 2006-09-01
ISBN: 0736954368
Category: Creationism
Language: EN, FR, DE, ES & NL

Reclaiming Science from Darwinism Book Excerpt:

"Foreword: William Dembski, PhD." Darwinism is a 150-year-old icon that has been propped up by unproven suppositions. The scientific discoveries of the last few decades are now kicking out the props. Dr. Kenneth Poppe is convinced the icon is ready to topple. Providing extensive scientific evidence of Darwinism's failures, this career biology instructor uses enlightening analogies and examples to explain the theory's problems: blind-luck assembly of the first cell mathematical "im"probabilities the laws of thermodynamics hypothetical sudden mutations biased mind-sets Spiced with humor and helpful graphics, this popularly targeted text shows readers that--in regard to objections to evolution--"the science is truly there." "A superior resource for students, parents, and private- or public-school educators."

Discovery and Explanation in Biology and Medicine

Discovery and Explanation in Biology and Medicine
Author: Kenneth F. Schaffner
Publsiher: University of Chicago Press
Total Pages: 654
Release: 1993
ISBN: 9780226735924
Category: Medical
Language: EN, FR, DE, ES & NL

Discovery and Explanation in Biology and Medicine Book Excerpt:

Kenneth F. Schaffner compares the practice of biological and medical research and shows how traditional topics in philosophy of science—such as the nature of theories and of explanation—can illuminate the life sciences. While Schaffner pays some attention to the conceptual questions of evolutionary biology, his chief focus is on the examples that immunology, human genetics, neuroscience, and internal medicine provide for examinations of the way scientists develop, examine, test, and apply theories. Although traditional philosophy of science has regarded scientific discovery—the questions of creativity in science—as a subject for psychological rather than philosophical study, Schaffner argues that recent work in cognitive science and artificial intelligence enables researchers to rationally analyze the nature of discovery. As a philosopher of science who holds an M.D., he has examined biomedical work from the inside and uses detailed examples from the entire range of the life sciences to support the semantic approach to scientific theories, addressing whether there are "laws" in the life sciences as there are in the physical sciences. Schaffner's novel use of philosophical tools to deal with scientific research in all of its complexity provides a distinctive angle on basic questions of scientific evaluation and explanation.

Discovery Science

Discovery Science
Author: Klaus P. Jantke,Ayumi Shinohara
Publsiher: Springer Science & Business Media
Total Pages: 510
Release: 2001-11-07
ISBN: 3540429565
Category: Computers
Language: EN, FR, DE, ES & NL

Discovery Science Book Excerpt:

These are the conference proceedings of the 4th International Conference on Discovery Science (DS 2001). Although discovery is naturally ubiquitous in s- ence, and scientific discovery itself has been subject to scientific investigation for centuries, the term Discovery Science is comparably new. It came up in conn- tion with the Japanese Discovery Science project (cf. Arikawa's invited lecture on The Discovery Science Project in Japan in the present volume) some time during the last few years. Setsuo Arikawa is the father in spirit of the Discovery Science conference series. He led the above mentioned project, and he is currently serving as the chairman of the international steering committee for the Discovery Science c- ference series. The other members of this board are currently (in alphabetical order) Klaus P. Jantke, Masahiko Sato, Ayumi Shinohara, Carl H. Smith, and Thomas Zeugmann. Colleagues and friends from all over the world took the opportunity of me- ing for this conference to celebrate Arikawa's 60th birthday and to pay tribute to his manifold contributions to science, in general, and to Learning Theory and Discovery Science, in particular. Algorithmic Learning Theory (ALT, for short) is another conference series initiated by Setsuo Arikawa in Japan in 1990. In 1994, it amalgamated with the conference series on Analogical and Inductive Inference (AII), when ALT was held outside of Japan for the first time.

Cells

Cells
Author: Martha London
Publsiher: ABDO
Total Pages: 35
Release: 2021-08-01
ISBN: 1098215613
Category: Juvenile Nonfiction
Language: EN, FR, DE, ES & NL

Cells Book Excerpt:

Living things are made of cells. Cells help living things grow. Cells looks at how these tiny units of life work and why they are important. Easy-to-read text, vivid images, and helpful back matter give readers a clear look at this subject. Features include a table of contents, infographics, a glossary, additional resources, and an index. Aligned to Common Core Standards and correlated to state standards. Kids Core is an imprint of Abdo Publishing, a division of ABDO.

Animal Classification

Animal Classification
Author: Emma Huddleston
Publsiher: ABDO
Total Pages: 35
Release: 2021-08-01
ISBN: 1098215605
Category: Juvenile Nonfiction
Language: EN, FR, DE, ES & NL

Animal Classification Book Excerpt:

Animals are all related. Some are more closely related than others. Scientists group them based on how they are related. Animal Classification looks at how scientists group animals, from least to most specific. Easy-to-read text, vivid images, and helpful back matter give readers a clear look at this subject. Features include a table of contents, infographics, a glossary, additional resources, and an index. Aligned to Common Core Standards and correlated to state standards. Kids Core is an imprint of Abdo Publishing, a division of ABDO.

Ecosystems

Ecosystems
Author: Martha London
Publsiher: ABDO
Total Pages: 35
Release: 2021-08-01
ISBN: 1098215621
Category: Juvenile Nonfiction
Language: EN, FR, DE, ES & NL

Ecosystems Book Excerpt:

Living and nonliving things all interact in an ecosystem. Fish swim and breathe in water. Trees take root in soil. Ecosystems looks at the important roles of living and nonliving things in an ecosystem. Easy-to-read text, vivid images, and helpful back matter give readers a clear look at this subject. Features include a table of contents, infographics, a glossary, additional resources, and an index. Aligned to Common Core Standards and correlated to state standards. Kids Core is an imprint of Abdo Publishing, a division of ABDO.

Textbooks in Academic Libraries

Textbooks in Academic Libraries
Author: Chris Diaz
Publsiher: American Library Association
Total Pages: 160
Release: 2018-12-03
ISBN: 0838915876
Category: Language Arts & Disciplines
Language: EN, FR, DE, ES & NL

Textbooks in Academic Libraries Book Excerpt:

Shortly after the syllabi are posted, and long before the beginning of the term, interlibrary loan departments at academic libraries will have filled or rejected innumerable textbook requests. While it would be unwise if not impossible to buy and circulate every textbook at a college or university, there are many academic libraries who are selectively adding textbooks to their collections. And the practice seems to be gaining momentum. In this volume, the Association for Library Collections and Technical Services (ALCTS) and editor Chris Diaz gather case studies that pull together creative approaches and best practices for print textbook reserve programs. This book discusses such topics as results and analysis from a detailed survey of a state university’s core-course textbook reserve program; funding sources for starting or piloting a program;using aggregated enrollment, grade, and textbook cost data to identify "high impact" courses;identifying course-related books that are in the library’s collection or fit an existing collection policy;workflow for using bookstore data with ILS and purchasing systems; andusing LibGuides and Google Sheets to publicize textbook holdings, and how a back-end database supports discovery for students and reporting for reserves staff. A textbook reserve program can be one way of helping students who are struggling with the high cost of textbooks, and this book spotlights a variety of examples that can be used as models.

Food Chains

Food Chains
Author: Emma Huddleston
Publsiher: ABDO
Total Pages: 35
Release: 2021-08-01
ISBN: 109821563X
Category: Juvenile Nonfiction
Language: EN, FR, DE, ES & NL

Food Chains Book Excerpt:

Living things need energy. Plants use sunlight to get energy they can use. Some animals get energy from eating plants. Other animals get energy from eating animals. Food Chains looks at how energy travels up a food chain. Easy-to-read text, vivid images, and helpful back matter give readers a clear look at this subject. Features include a table of contents, infographics, a glossary, additional resources, and an index. Aligned to Common Core Standards and correlated to state standards. Kids Core is an imprint of Abdo Publishing, a division of ABDO.

Genetics

Genetics
Author: Emma Huddleston
Publsiher: ABDO
Total Pages: 35
Release: 2021-08-01
ISBN: 1098215648
Category: Juvenile Nonfiction
Language: EN, FR, DE, ES & NL

Genetics Book Excerpt:

Living things have different traits. These traits are caused by the genes living things get from their parents. Genetics looks at how genes influence traits and how to find out how likely it is to get a trait. Easy-to-read text, vivid images, and helpful back matter give readers a clear look at this subject. Features include a table of contents, infographics, a glossary, additional resources, and an index. Aligned to Common Core Standards and correlated to state standards. Kids Core is an imprint of Abdo Publishing, a division of ABDO.

Compassion

Compassion
Author: Roger A. Lewin
Publsiher: Jason Aronson, Incorporated
Total Pages: 348
Release: 1996-03-01
ISBN: 1461734584
Category: Psychology
Language: EN, FR, DE, ES & NL

Compassion Book Excerpt:

This text is an attempt to stimulate and support therapists' efforts to take care of themselves, to understand and maintain commitment. Such reflection, it argues helps therapists to be active and receptive.