Dynamics Of Biological Macromolecules By Neutron Scattering

Author by : Salvatore Magazù
Languange : en
Publisher by : Bentham Science Publishers
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Description : Dynamics of Biological Macromolecules by Neutron Scattering provides insight into the study of the dynamics of biological macromolecules by neutron scattering techniques. The applicability of neutron scattering to expanding fields of biological studies is


Dynamics Of Biological Macromolecules By Neutron Scattering Title Pdf 02 Cover Page 03 Ebooks End User License Agreement Website 05 Foreword 06 Preface 07 List Of Contributors 08 Section I 09 Chapter 01 10 Chapter 02 11 Section Ii 12 Chapter 03 13 Chapter 04 14 Section Iii 15 Chapter 05 16 Chapter 06 17 Section Iv 18 Chapter 07 19 Chapter 08 20 Author Index 21 Subject Index

Author by : Salvatore Magazù
Languange : en
Publisher by : Unknown
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Description : Dynamics of Biological Macromolecules by Neutron Scattering provides insight into the study of the dynamics of biological macromolecules by neutron scattering techniques. The applicability of neutron scattering to expanding fields of biological studies is very extended and the neutron scattering community is interested in using these unique technologies to their best advantage. The book is focused on recent scientific results on biomolecular motions obtained by using neutron spectroscopy, and also discusses likely directions of future work on biological macromolecular systems while outlining s.


Dynamics Of Soft Matter

Author by : VICTORIA GARCIA SAKAI
Languange : en
Publisher by : Springer Science & Business Media
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Description : Dynamics of Soft Matter: Neutron Applications provides an overview of neutron scattering techniques that measure temporal and spatial correlations simultaneously, at the microscopic and/or mesoscopic scale. These techniques offer answers to new questions arising at the interface of physics, chemistry, and biology. Knowledge of the dynamics at these levels is crucial to understanding the soft matter field, which includes colloids, polymers, membranes, biological macromolecules, foams, emulsions towards biological & biomimetic systems, and phenomena involving wetting, friction, adhesion, or microfluidics. Emphasizing the complementarities of scattering techniques with other spectroscopic ones, this volume also highlights the potential gain in combining techniques such as rheology, NMR, light scattering, dielectric spectroscopy, as well as synchrotron radiation experiments. Key areas covered include polymer science, biological materials, complex fluids and surface science.


Spectroscopy Of Biological Molecules

Author by : M.P. Marques
Languange : en
Publisher by : IOS Press
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Description : This book presents contributions from some of the leading experts in spectroscopic techniques including infrared, Raman, NMR, fluorescence and Circular Dichroism spectroscopy. Structural characterization of biomolecules, cells, tissues and whole organisms are amongst the topics that were covered by these experts at the 14th European Conference on Spectroscopy of Biological Molecules (ECSBM2011), held at the University of Coimbra, Portugal, from 29th August to 3rd September 2011, of which this book contains the papers. The book would be particularly valuable for those interested in vibrational spectroscopy and imaging of cells and tissues, applications of spectroscopy in biotechnology, single cell studies and microbial characterization. It highlights the potential of spectroscopy and imaging in medical diagnosis and screening, and discusses issues related to methodology, including data acquisition, analysis and processing, that would be valuable for scientists who are new to the field. The book would be an important reference source for scientists in academia and industry as well as early stage researchers such as graduate students and post-doctoral researchers.


Biological Small Angle Scattering Techniques Strategies And Tips

Author by : Barnali Chaudhuri
Languange : en
Publisher by : Springer
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Description : This book provides a clear, comprehensible and up-to-date description of how Small Angle Scattering (SAS) can help structural biology researchers. SAS is an efficient technique that offers structural information on how biological macromolecules behave in solution. SAS provides distinct and complementary data for integrative structural biology approaches in combination with other widely used probes, such as X-ray crystallography, Nuclear magnetic resonance, Mass spectrometry and Cryo-electron Microscopy. The development of brilliant synchrotron small-angle X-ray scattering (SAXS) beam lines has increased the number of researchers interested in solution scattering. SAS is especially useful for studying conformational changes in proteins, highly flexible proteins, and intrinsically disordered proteins. Small-angle neutron scattering (SANS) with neutron contrast variation is ideally suited for studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatography further increases the range of SAS applications. The book is written by leading experts in solution SAS methodologies. The principles and theoretical background of various SAS techniques are included, along with practical aspects that range from sample preparation to data presentation for publication. Topics covered include techniques for improving data quality and analysis, as well as different scientific applications of SAS. With abundant illustrations and practical tips, we hope the clear explanations of the principles and the reviews on the latest progresses will serve as a guide through all aspects of biological solution SAS. The scope of this book is particularly relevant for structural biology researchers who are new to SAS. Advanced users of the technique will find it helpful for exploring the diversity of solution SAS methods and applications. Chapter 3 of this book is available open access under a CC BY 4.0 license at link.springer.com.


Neutron Scattering In Biology

Author by : Jörg Fitter
Languange : en
Publisher by : Springer Science & Business Media
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Description : The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.


Neutron Scattering In Novel Materials

Author by : Albert Furrer
Languange : en
Publisher by : World Scientific
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Description : This book provides an introduction to the basic principles of neutron scattering and its application to current problems in condensed matter science and technology. Experiments on novel materials are particularly emphasized.


Neutron Scattering In Novel Materials

Author by : Albert Furrer
Languange : en
Publisher by : World Scientific
Format Available : PDF, ePub, Mobi
Total Read : 86
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Description : This book provides an introduction to the basic principles of neutron scattering and its application to current problems in condensed matter science and technology. Experiments on novel materials are particularly emphasized. Contents:Introduction:Principles of Neutron Scattering (P Böni et al.)Materials Science:Neutron Imaging (E H Lehmann)Neutron Tomography (B Schillinger)Neutron Powder Diffraction and New Materials (A W Hewat)Texture, Strain and Precipitates (M Grosse)Scattering Between Bragg Peaks (B Schönfeld)Optically Active Materials (R A Rupp)Soft Condensed Matter and Biology:Introduction to Soft Matter Systems (M Monkenbusch)SANS of Polymer Networks Under Deformation (W Pyckhout-Hintzen et al.)Dynamics of Polymer Systems (A Arbe)Biomolecular Dynamics by Neutron Scattering (H D Middendorf)Spin Contrast Variation for Macromolecular Research (O Zimmer)Surfaces and Interfaces:Neutron Reflectometry: Technique and Applications (D Clemens)Nanocrystalline Materials: Dominance of Interfaces and Mesoscopic Correlations (W Wagner et al.)Rare-Earth Compounds:Magnetic Ordering Phenomena in Rare-Earth Compounds (L Keller)Crystal-Field Phenomena in Rare-Earth Compounds (A Mirmelstein)Magnetic Excitations:Spin Excitations in Localized and Itinerant Magnets (B Roessli & P Böni)Triplet Excitations in a Family of S=1/2 Unconventional Antiferromagnets (N Cavadini et al.)Superconductivity and Superfluidity:Spin Dynamics in Cuprates and Its Relation to Superconductivity (Ph Bourges)Using Neutrons and Muons to Probe the Vortex Lattice in Type II Superconductors (S L Lee)Magnetic and Electronic Excitations in High-Temperature Superconductors (J Mesot)Superfluid 4Helium — A Very Novel Material (M A Adams)Summary:Summary of the School (W E Fischer) Readership: Materials scientists and condensed matter scientists. Keywords:Neutron Scattering;Neutron Imaging;Soft Matter Systems;Rare-Earth Compounds;Magnetic Excitations;Superconductivity and Superfluidity


Small Angle X Ray And Neutron Scattering From Solutions Of Biological Macromolecules

Author by : Dmitri I. Svergun
Languange : en
Publisher by : OUP Oxford
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Description : Small-angle scattering of X-rays (SAXS) and neutrons (SANS) is an established method for the structural characterization of biological objects in a broad size range from individual macromolecules (proteins, nucleic acids, lipids) to large macromolecular complexes. SAXS/SANS is complementary to the high resolution methods of X-ray crystallography and nuclear magnetic resonance, allowing for hybrid modeling and also accounting for available biophysical and biochemical data. Quantitative characterization of flexible macromolecular systems and mixtures has recently become possible. SAXS/SANS measurements can be easily performed in different conditions by adding ligands or binding partners, and by changing physical and/or chemical characteristics of the solvent to provide information on the structural responses. The technique provides kinetic information about processes like folding and assembly and also allows one to analyze macromolecular interactions. The major factors promoting the increasingly active use of SAXS/SANS are modern high brilliance X-ray and neutron sources, novel data analysis methods, and automation of the experiment, data processing and interpretation. In this book, following the presentation of the basics of scattering from isotropic macromolecular solutions, modern instrumentation, experimental practice and advanced analysis techniques are explained. Advantages of X-rays (rapid data collection, small sample volumes) and of neutrons (contrast variation by hydrogen/deuterium exchange) are specifically highlighted. Examples of applications of the technique to different macromolecular systems are considered with specific emphasis on the synergistic use of SAXS/SANS with other structural, biophysical and computational techniques.


A Practical Guide To Quasi Elastic Neutron Scattering

Author by : Mark T F Telling
Languange : en
Publisher by : Royal Society of Chemistry
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Description : The technique of Quasi-Elastic Neutron Scattering (QENS) is a powerful experimental tool for extracting temporal and spatial information at the nanoscale from both soft and hard condensed matter systems. However, while seemingly simple, the method is beset with sensitivities that, if ill considered, can hinder data interpretation and possibly publication. By highlighting key theoretical and data evaluation aspects of the technique, this specialised ‘primer style’ training resource encourages research success by guiding new researchers through a typical QENS experiment; from planning and sample preparation considerations to data reduction and subsequent analysis. Research examples are referenced throughout to illustrate the concepts addressed, with the book being written in such a way that it remains accessible to chemists, biologists, physicists, and materials scientists.


Neutron Scattering In Biology

Author by : Jörg Fitter
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 79
Total Download : 826
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Description : The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.


Neutron Scattering Advances And Applications

Author by : M.M. Elcombe
Languange : en
Publisher by : Trans Tech Publications Ltd
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Description : Materials Science Forum Vols. 27-28


Macromolecular Crystallography

Author by : Maria Armenia Carrondo
Languange : en
Publisher by : Springer
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Description : This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.


Neutron Scattering Applications In Biology Chemistry And Materials Science

Author by : Felix Fernandez-Alonso
Languange : en
Publisher by : Elsevier
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Description : Neutron Scattering: Applications in Chemistry, Materials Science and Biology, Volume 49, provides an in-depth overview of the applications of neutron scattering in the fields of physics, materials science, chemistry, biology, the earth sciences, and engineering. The book describes the tremendous advances in instrumental, experimental, and computational techniques over the past quarter-century. Examples include the coming-of-age of neutron reflectivity and spin-echo spectroscopy, the advent of brighter accelerator-based neutron facilities and associated techniques in the United States and Japan over the past decade, and current efforts in Europe to develop long-pulse, ultra-intense spallation neutron sources. It acts as a complement to two earlier volumes in the Experimental Methods in the Physical Science series, Neutron Scattering: Fundamentals(Elsevier 2013) and Neutron Scattering: Magnetic and Quantum Phenomena (Elsevier 2015). As a whole, the set enables researchers to identify aspects of their work where neutron scattering techniques might contribute, conceive the important experiments to be done, assess what is required, write a successful proposal for one of the major facilities around the globe, and perform the experiments under the guidance of the appropriate instrument scientist. Completes a three-volume set, providing extensive coverage on emerging and highly topical applications of neutron scattering Addresses the increasing use of neutrons by chemists, life scientists, material scientists, and condensed-matter physicists Presents up-to-date reviews of recent results, enabling readers to identify new opportunities and plan neutron scattering experiments in their own field


Spectroscopy Of Biological Molecules Modern Trends

Author by : P. Carmona
Languange : en
Publisher by : Springer Science & Business Media
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Description : The 1997 European Conference on Spectroscopy of Biological Molecules (ECSBM) is the seventh in a biennial series of conferences devoted to the applications of molecular spectroscopy to biological molecules and related systems. The interest of these conferences rests mainly on the relationship between the structure and physiological activity of biological molecules and related systems of which these molecular species form part. This volume ofECSBM contains articles prepared by the invited lecturers and those making poster presentations at the seventh ECSBM. The reader will find mainly applications of vibrational spectroscopy to protein structure and dynamics, biomembranes, molecular recognition, nucleic acids and other biomolecules and biological systems containing specific chromophors. Biomedical applications of vibrational spectroscopy are expanding rapidly. On the other hand, a significant number of the papers describe applications of other methods, such as NMR, circular dichroism, optical absorption and fluorescence, X-ray absorption and diffraction and other theoretical methods. One aim has been to achieve a well balanced, critically comparative review of recent progress in the field of biomolecular structure, bonding and dynamics based on applications of the above spectroscopic methods. A great part of the contributions included in this volume are devoted to biomedical and biotechnological applications and provide a broadly based account of recent applicationS in this field. The content of this book has been organized in sections corresponding mainly to the different types of biological molecules investigated. This book includes also another section related to theoretical methods where MO calculations of vibrational frequencies dominate clearly the topic.


Hydration Processes In Biology

Author by : Marie-Claire Bellissent-Funel
Languange : en
Publisher by : IOS Press
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Description : The interaction of water at organic surfaces or interfaces is of fundamental and technological interest and importance in chemistry, physics and biology. Progress towards an in-depth, molecular interpretation of the structure and dynamics of interfacial water needs a range of novel experimental and simulation techniques. We are now reaching the stage at which we understand, at the molecular level, the mutual perturbation at a macromolecule/water interface. The aims of this book are to provide with a comprehensive background to the properties of bulk water at the microscopic level and with a substantial account of the theoretical and experimental contributions which have been done to understand the role of water in various systems from some model systems to the more complex ones such as the biological systems.


Isotope Labeling Of Biomolecules Applications

Author by : Anonim
Languange : en
Publisher by : Academic Press
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Description : Isotope Labeling of Biomolecules: Applications, the latest in the Methods in Enzymology series, focuses on stable isotope labeling methods and applications for biomolecules. This practical guide to biomolecular labeling looks at new techniques that are becoming widely used. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Focuses on stable isotope labeling of biomolecules, which is important for structural studies of proteins and nucleic acids


Los Alamos Science

Author by : Anonim
Languange : en
Publisher by : Unknown
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Description :


Vibrational Spectroscopy With Neutrons

Author by : Philip C H Mitchell
Languange : en
Publisher by : World Scientific
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Description : ' Inelastic neutron scattering (INS) is a spectroscopic technique in which neutrons are used to probe the dynamics of atoms and molecules in solids and liquids. This book is the first, since the late 1960s, to cover the principles and applications of INS as a vibrational-spectroscopic technique. It provides a hands-on account of the use of INS, concentrating on how neutron vibrational spectroscopy can be employed to obtain chemical information on a range of materials that are of interest to chemists, biologists, materials scientists, surface scientists and catalyst researchers. This is an accessible and comprehensive single-volume primary text and reference source. Contents:The Theory of Inelastic Neutron Scattering SpectroscopyInstrumentation and Experimental MethodsInterpretation and Analysis of Spectra Using Molecular ModellingAnalysis of INS SpectraDihydrogen and HydridesSurface Chemistry and CatalysisOrganic and Organometallic CompoundsHydrogen BondingSoft Condensed Matter — Polymers and BiomaterialsNon-Hydrogenous Materials and CarbonVibrational Spectroscopy with Neutrons — The Future Readership: Users and potential users of neutron scattering spectroscopy (academics, staff of neutron scattering institutes, researchers and graduate students); solid state vibrational spectroscopists. Keywords:Inelastic Neutron Scattering;Vibrational Spectroscopy;Hydrogen;Solid State;Density Functional Theory;Hydrogen Bonding;Water;Proton;Polymer;Biominerals;Phosphate;Catalyst;Zeolite;Sulfide;Cross SectionKey Features:Acquaints the reader with the basic concepts of neutron scatteringOffers an insight into how theory and experiment connect in the interpretation of INS scattering dataShows how useful information can be extracted from experimental dataDescribes studies of dihydrogen and its compounds using INS spectroscopyProvides a comprehensive listing of compounds and materials studied by INSReviews:“This book provides a very good account of the principles and applications of Inelastic Neutron Scattering (INS) as a vibrational spectroscopic technique, without assuming a high level of background knowledge. It is a piece of work factually novel and done properly, which meets the needs of graduate students as well as both users and potential users of inelastic neutron spectroscopy at academic and research institutions. On the whole the book is quite clearly written, the subject matter rather well developed and the applications of the INS well described in a wide range of materials and problems.”Notiziario Neutroni e Luce di Sincrotrone '


Physical Biology Of Proteins And Peptides

Author by : Luis Olivares-Quiroz
Languange : en
Publisher by : Springer
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Description : This book covers the latest developments in the physical biology of proteins and peptides. Key insights into microscopic and macroscopic approaches to describe biologically relevant macromolecules and their interactions are provided. This book also covers a wide range of tools, including theoretical methods as statistical mechanics, normal mode analysis, kinetic theory and stochastic processes, and all-atom and coarse-grained molecular dynamics simulations. New experimental techniques are also discussed, particularly related to amiloidogenic peptides and their mutations. This is an excellent book for molecular biologists, physicists, computational scientists, and chemists. It covers cutting-edge research in this exciting, interdisciplinary research field. This book also: Discusses the latest developments in the physical biology of proteins, peptides and enzymes covering theoretical, computational, and experimental approaches Broadens readers’ understanding on the r ole of intra- and inter-molecular interactions as a fundamental cornerstone of macroscopic biological properties of macromolecules Provides a wide and useful perspective on different aspects of the physics, biology, and chemistry of proteins and peptides suitable for interdisciplinary research.


Neutron X Rays And Light Scattering Methods Applied To Soft Condensed Matter

Author by : Th Zemb
Languange : en
Publisher by : North-Holland
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Description : Scattering experiments, using X-ray, light and neutron sources (in historical order) are key techniques for studying structure and dynamics in systems containing colliods, polymers, surfactants and biological macromolecules, summarized here as soft condensed matter. The education in this field in Europe is very heterogeneous and frequently inadequate, which severely limits an efficient use of these methods, especially at large-scale facilities. The series of "Bombannes" schools and the completely revised and updated second edition of the lecture notes are devoted to a practical approach to current methodology of static and dynamic techiques. Basic information on data interpretation, on the complementarity of the different types of radiation, as well as information on recent applications and developments is presented. The aim is to avoid over - as well as under-exploitation of data.


Pharmaceutical Nanotechnology

Author by : Jean Cornier
Languange : en
Publisher by : John Wiley & Sons
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Description : With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!


The Encylopedia Of Molecular Biology

Author by : Sir John Kendrew
Languange : en
Publisher by : John Wiley & Sons
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Description : The Encylopaedia of Molecular Biology is a truly unique work of reference. 6000 definitions cover the entire spectrum of molecular life science The complete one-volume guide to understanding the way molecular biology is transforming medicine and agriculture Long and short entries written by over 300 of the world's finest researchers For rapid research or detailed study ... this is the A to Z of the New Biology


Water And Biological Macromolecules

Author by : Westhof
Languange : en
Publisher by : CRC Press
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Description : Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists.


Dielectric Relaxation In Biological Systems

Author by : Valerica Raicu
Languange : en
Publisher by : Oxford University Press, USA
Format Available : PDF, ePub, Mobi
Total Read : 49
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Description : This title covers the theoretical basis and practical aspects of the study of dielectric properties of biological systems, such as water, electrolyte and polyelectrolytes, solutions of biological macromolecules, cells suspensions and cellular systems.


Neutrons In Biology

Author by : Benno P. Schoenborn
Languange : en
Publisher by : Springer Science & Business Media
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Total Read : 19
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Description :


Encyclopedia Of Supramolecular Chemistry

Author by : J. L. Atwood
Languange : en
Publisher by : CRC Press
Format Available : PDF, ePub, Mobi
Total Read : 28
Total Download : 647
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Description : Crystallizing a rapidly expanding interdisciplinary field and one of the most popular and newsworthy areas in contemporary chemistry, this two-volume encyclopaedia offers authoritative information with user-friendly and high-quality articles.


Erda Energy Research Abstracts

Author by : United States. Energy Research and Development Administration
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 34
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Description :