Early Detection in Alzheimer s Disease

Early Detection in Alzheimer s Disease
Author: Dennis Chan
Publsiher: Academic Press
Total Pages: 300
Release: 2021-09-15
ISBN: 9780128222409
Category: Medical
Language: EN, FR, DE, ES & NL

Early Detection in Alzheimer s Disease Book Excerpt:

Early Detection of Alzheimer's Disease aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer's Association, 5.8 million Americans are living with Alzheimer's and care costs will cost the nation approximately $290 billion (2019 Alzheimer's Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of symptoms. Topics covered include the use of sensing technologies (eg smartphones, smartwatches, Internet of Things) to detect early disease-related changes , the application of data science (machine learning/AI) to extract otherwise invisible disease features from these datasets and the potential to personalize diagnosis based on tracking changes in individual behaviours. Advances in blood-based biomarkers, brain imaging, and the potential for early diagnosis to aid interventions (lifestyle, dietary, pharmacological) to delay future development of dementia are also discussed. Outlines the importance of early diagnosis of Alzheimer's Disease Helps readers understand the limitations of current clinical approaches and the need for a paradigmatic shift in diagnostic practice Discusses the potential role of technology in clinical practice using machine learning and artificial intelligence and the potential to personize diagnosis and treatment

Early Detection of Alzheimer s Disease and Dementia in the General Population

Early Detection of Alzheimer s Disease and Dementia in the General Population
Author: Katie Palmer
Publsiher: Unknown
Total Pages: 71
Release: 2004
ISBN: 9789171400550
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Early Detection of Alzheimer s Disease and Dementia in the General Population Book Excerpt:

Early Diagnosis and Intervention in Predementia Alzheimer s Disease An Issue of Medical Clinics

Early Diagnosis and Intervention in Predementia Alzheimer s Disease  An Issue of Medical Clinics
Author: Jose L. Molinuevo,Jeffrey I. Cummings,Bruno Dubois,Philip Scheltens
Publsiher: Elsevier Health Sciences
Total Pages: 156
Release: 2013-05-11
ISBN: 1455772038
Category: Medical
Language: EN, FR, DE, ES & NL

Early Diagnosis and Intervention in Predementia Alzheimer s Disease An Issue of Medical Clinics Book Excerpt:

This issue of Medical Clinics covers the important advances surrounding the early intervention of Alzheimer's Disease. Guest edited by world-renowned experts from around the world, the topics covered will include evaluation of new diagnostic criteria, CSF biomarkers, diagnostic imaging, neurocognitive approaches, breaking clinical trials and more.

Senile Dementias

Senile Dementias
Author: André Bès
Publsiher: Unknown
Total Pages: 664
Release: 1986
ISBN: 1928374650XXX
Category: Alzheimer's disease
Language: EN, FR, DE, ES & NL

Senile Dementias Book Excerpt:

Alzheimer s Disease

Alzheimer s Disease
Author: Robert Becker
Publsiher: CRC Press
Total Pages: 300
Release: 2020-07-24
ISBN: 1000162850
Category: Medical
Language: EN, FR, DE, ES & NL

Alzheimer s Disease Book Excerpt:

This book examines the relevance of current research for the early diagnosis of Alzheimer disease. It uncovers the present lack of clinical utility in research methodologies such as neuroimaging, drug challenges, electroencephalographs studies, and brain biopsy.

Finding the Path in Alzheimer s Disease

Finding the Path in Alzheimer   s Disease
Author: Sharon Cohen, MD, FRCPC,R. Scott Turner, MD, PhD
Publsiher: Integritas Communications
Total Pages: 40
Release: 2020-11-19
ISBN: 1928374650XXX
Category: Health & Fitness
Language: EN, FR, DE, ES & NL

Finding the Path in Alzheimer s Disease Book Excerpt:

AD is a common neurodegenerative condition that results in a range of profoundly disabling cognitive, affective, and behavioral symptoms. It affects approximately 5.8 million Americans. Barring significant clinical efforts and medical breakthroughs that prevent or slow disease development, current estimates suggest that by 2050, AD will afflict 14 million patients in the United States. PCPs are on the front lines of early diagnosis of AD, yet many say they feel unprepared and their community lacks adequate specialists in this area. Signs and symptoms of mild cognitive impairment (MCI) and even early AD are often conflated with normal aging, leading to late or missed diagnosis. This is compounded by the lack of a sense of urgency for early, accurate diagnosis because there are no disease-modifying therapies to treat MCI or AD. This eHealth Source activity reviews the pathophysiology of AD, early signs and symptoms, diagnosis first steps, referral patterns, more-complex diagnostic procedures, and existing nonpharmacologic and pharmacologic management strategies. Drs Cohen and Turner provide expert insight into how PCPs can tailor their practice to better care for these patients.

Mild Cognitive Impairment and Early Alzheimer s Disease

Mild Cognitive Impairment and Early Alzheimer s Disease
Author: Jeffrey M. Burns,John C. Morris
Publsiher: John Wiley & Sons Incorporated
Total Pages: 168
Release: 2008-05-27
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Mild Cognitive Impairment and Early Alzheimer s Disease Book Excerpt:

Written by leading authorities in the field, this book describes the cognitive changes associated with age, the earliest detectable stages of Alzheimer’s, and the relationship of these conditions to MCI. The authors review the latest advances in our understanding of MCI, its prevalence, evaluation, management, and outcomes and in so doing provide practising physicians with a useful resource that assists them in identifying those MCI patients who will progress to recognised Alzheimer’s Disease. Beautifully presented in full colour, Early Diagnosis and Treatment of Mild Cognitive Impairment includes case studies and discusses future therapeutic and diagnostic strategies. It is an invaluable resource for postgraduates and professionals, for specialist physicians in neurology and psychiatric medicine, geriatric medicine and general practice.

Early Detection and Rehabilitation Technologies for Dementia Neuroscience and Biomedical Applications

Early Detection and Rehabilitation Technologies for Dementia  Neuroscience and Biomedical Applications
Author: Wu, Jinglong
Publsiher: IGI Global
Total Pages: 480
Release: 2011-05-31
ISBN: 1609605608
Category: Medical
Language: EN, FR, DE, ES & NL

Early Detection and Rehabilitation Technologies for Dementia Neuroscience and Biomedical Applications Book Excerpt:

"This book provides a comprehensive collection for experts in the Neuroscience and Biomedical technology fields, outlining various concepts from cognitive neuroscience and dementia to neural technology and rehabilitation"--Provided by publisher.

Early Detection of Alzheimer s Disease with Cognitive Neuroscience Methods

Early Detection of Alzheimer s Disease with Cognitive Neuroscience Methods
Author: Jinglong Wu,Chunlin Li,Jiajia Yang
Publsiher: Unknown
Total Pages: 135
Release: 2011
ISBN: 9789533074504
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Early Detection of Alzheimer s Disease with Cognitive Neuroscience Methods Book Excerpt:

Early Diagnosis of Alzheimer s Disease

Early Diagnosis of Alzheimer   s Disease
Author: Leonard F. M. Scinto,Kirk R. Daffner
Publsiher: Springer Science & Business Media
Total Pages: 359
Release: 2000-02-09
ISBN: 1592590055
Category: Medical
Language: EN, FR, DE, ES & NL

Early Diagnosis of Alzheimer s Disease Book Excerpt:

Drs. Leonard Scinto and Kirk Daffner provide a comprehensive survey of new diagnostic approaches to Alzheimer's disease. The authoritative contributors critically survey the most promising current research on early diagnostic markers for Alzheimer's disease, including the elucidation of changes in the brain revealed by structural and functional neuroimaging, as well as the characteristic patterns of cognitive decline that are documented by sensitive neuropsychological tests, various genetic markers, and biological assays. Early Diagnosis of Alzheimer's Disease illuminates the complex issues surrounding the search for early markers of this increasingly widespread disease. It will establish a new standard reference guide for all those working with Alzheimer's patients.

Early Markers in Parkinson s and Alzheimer s Diseases

Early Markers in Parkinson   s and Alzheimer   s Diseases
Author: Philippe Dostert,Peter Riederer,Margherita Strolin Benedetti,Romeo Roncucci
Publsiher: Springer Science & Business Media
Total Pages: 310
Release: 2012-12-06
ISBN: 3709190983
Category: Medical
Language: EN, FR, DE, ES & NL

Early Markers in Parkinson s and Alzheimer s Diseases Book Excerpt:

The aim of Early Markers in Parkinson's and Alzheimer's Diseases is to provide the reader with updated data on various approaches whose investigation and development could contribute to the discovery of early diag- nostic markers of these two degenerative diseases. Concerning Parkinson's disease, some of the topics dealt with in the book will help update the information previously reported in Early Diagnosis and Preventive Therapy in Parkinson's Disease. Concerning Alzheimer's disease, the scope and limitations of electrophysiological and brain imaging techniques with regards to early detection of the disease are documented. Various biochemical parameters, such as brain energy metabolism, levels of choline, and platelet monoamine oxidase activity are envisaged as some of the starting points for the discovery of early diagnostic markers of Alzheimer's disease.

Biomarkers for Early Diagnosis of Alzheimer s Disease

Biomarkers for Early Diagnosis of Alzheimer s Disease
Author: Daniela Galimberti,Elio Scarpani
Publsiher: Nova Science Publishers
Total Pages: 307
Release: 2008
ISBN: 1928374650XXX
Category: Alzheimer's disease
Language: EN, FR, DE, ES & NL

Biomarkers for Early Diagnosis of Alzheimer s Disease Book Excerpt:

Alzheimer's disease (AD) is characterized by the deposition into the brain of amyloid peptide, which originates a cascade of inflammatory events leading eventually to neuronal death. These pathological events likely occur several years before the clinical manifestation of the disease, implying that potential therapeutical interventions are currently started too late to give beneficial results. Recently, growing attention has been paid to the Mild Cognitive Impairment (MCI), considered the prodromal phase of AD, as 80% of subjects with MCI have been shown to develop AD within 5 years. Several studies aimed to identify biological markers to differentiate between normal aging and incipient AD have been carried out, including cerebrospinal fluid (CSF) analysis and neuroimaging. In particular, the evaluation of CSF Amyloid beta (1-42) levels, together with tau and phospotau, are of help for recognizing early AD. Besides, a number of additional molecules are altered in CSF. Other early modifications have been observed in peripheral cells, such as fibroblasts and leukocytes, as well as in serum from patients. Biomarkers for AD represent important tools supporting the clinical diagnosis and the choice of potential therapeutic options. Moreover, they would be of great help for the selection of cohorts of homogeneous patients for clinical trials with new disease-modifying compounds. This book is aimed to give an update about MCI as prodromal Alzheimer's disease (AD), to discuss the main known pathological mechanisms at the basis of AD and to describe the possible biomarkers to be used for an early diagnosis of the disease.

Emerging Technologies for Diagnosing Alzheimer s Disease

Emerging Technologies for Diagnosing Alzheimer s Disease
Author: Marianne Boenink,Harro van Lente,Ellen Moors
Publsiher: Springer
Total Pages: 286
Release: 2016-09-13
ISBN: 1137540974
Category: Social Science
Language: EN, FR, DE, ES & NL

Emerging Technologies for Diagnosing Alzheimer s Disease Book Excerpt:

This book explores international biomedical research and development on the early diagnosis of Alzheimer's disease. It offers timely, multidisciplinary reflections on the social and ethical issues raised by promises of early diagnostics and asks under which conditions emerging diagnostic technologies can be considered a responsible innovation. The initial chapters in this edited volume provide an overview and a critical discussion of recent developments in biomedical research on Alzheimer's disease. Subsequent contributions explore the values at stake in current practices of dealing with Alzheimer's disease and dementia, both within and outside the biomedical domain. Novel diagnostic technologies for Alzheimer's disease emerge in a complex and shifting field, full of controversies. Innovating with care requires a precise mapping of how concepts, values and responsibilities are filled in through the confrontation of practices. In doing so, the volume offers a practice-based approach of responsible innovation that is also applicable to other fields of innovation.

Alzheimers Test and Prevention

Alzheimers Test and Prevention
Author: Brian Jeff
Publsiher: Createspace Independent Publishing Platform
Total Pages: 135
Release: 2016-10-13
ISBN: 9781539500377
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Alzheimers Test and Prevention Book Excerpt:

There is no doubt that Alzheimer's disease is a complex and complicated illness, and the reason for this is that most of its symptoms are frequently indicative of other disorders as well! Well, as a result, the diagnostic process for the disease can be really messy and complicated if you know what I mean. And as a matter of fact, at this time, the only definitive way to diagnose Alzheimer's disease is to examine brain tissue for plaques and tangles. But, let me quickly say that this is rather unfortunate! And you should know why... yes, because so far, this can only be done in an autopsy! So you might be wondering... "How then is Alzheimer's disease diagnosed?" Well, doctors must do what they have to do to get the right diagnosis... so they have to conduct a thorough examination so that they can rule out other possible causes of the symptoms you are experiencing. Therefore, to a larger extent, I want to say that a diagnosis can be considered "reasonable" if all other causes cannot be excluded. But same can be considered "probable" if all other causes have been ruled out. Fortunately, today we have specialists with extensive experience of working with Alzheimer's disease patients that can diagnose Alzheimer's disease with 80-90% certainty. Early Diagnosis - Don't Waste Time before Seeing a Doctor. Yes, according to Dharma Singh Khalsa, M.D., President and Medical Director of the Alzheimer's Disease Research and Prevention Foundation, it is important that you go for a diagnostic examination as soon as symptoms appear. In any case, Dr. Khalsa has found that many of the treatments currently available work best when an early Alzheimer's disease diagnosis is made. Besides that, there are many other advantages to having Alzheimer's disease diagnosed as early as possible. First, early diagnosis help patients and families plan for the future. It gives them time to discuss care options while the patient can still be part of the decision-making process. That will be okay for now... just get your copy of the book today by clicking the buy button above and avail yourself the full details of how to test, prevent and as the case may be, start to manage the condition with ease. Yes, Including Tips To Avoid The Early Onset Alzheimer's And Chronic Alzheimer's Disease Stages Today!

Alzheimer s Disease

Alzheimer   s Disease
Author: Ralph W. Richter,Brigitte Zoeller Richter
Publsiher: Springer Science & Business Media
Total Pages: 479
Release: 2003-10-10
ISBN: 1592596614
Category: Medical
Language: EN, FR, DE, ES & NL

Alzheimer s Disease Book Excerpt:

Alzheimer’s disease (AD) is a devastating and dehumanizing illness affecting increasingly large numbers of elderly and even middle-aged persons in a worldwide epidemic. Alzheimer’s Disease: A Physician’s Guide to Practical Management was written by selected clinicians and scientists who represent some of the world’s leading centers of excellence in AD research. The editors are proud and grateful for their profound contributions. This book is particularly designed to assist physicians and other health-care professionals in the evaluation, assessment, and treatment of individuals with AD. At the same time, by illuminating the basic scientific background, we hope to provide state-of-the art information about the disease and possible future therapeutic strategies. The recent psychiatric treatment aspects of AD are also clearly presented. Because the early diagnosis of the dementia process is now considered of increasing importance, we focus particularly in several chapters on early changes and preclinical conditions, such as mild cognitive impairment and predementia AD.

Early Diagnosis of Alzheimer s Disease

Early Diagnosis of Alzheimer s Disease
Author: Leonard F M Scinto,Kirk R Daffner
Publsiher: Unknown
Total Pages: 376
Release: 2000-02-09
ISBN: 9781468496000
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Early Diagnosis of Alzheimer s Disease Book Excerpt:

Early Diagnosis and Intervention in Predementia Alzheimer s Disease an Issue of Medical Clinics

Early Diagnosis and Intervention in Predementia Alzheimer s Disease  an Issue of Medical Clinics
Author: José L. Molinuevo,Jeffrey I. Cummings,Bruno Dubois,Philip Scheltens
Publsiher: Elsevier
Total Pages: 15
Release: 2013
ISBN: 9781455771172
Category: Medical
Language: EN, FR, DE, ES & NL

Early Diagnosis and Intervention in Predementia Alzheimer s Disease an Issue of Medical Clinics Book Excerpt:

This issue of Medical Clinics covers the important advances surrounding the early intervention of Alzheimer's Disease. Guest edited by world-renowned experts from around the world, the topics covered will include evaluation of new diagnostic criteria, CSF biomarkers, diagnostic imaging, neurocognitive approaches, breaking clinical trials and more.

The Dementias

The Dementias
Author: Karl Herholz,Daniela Perani,Chris Morris
Publsiher: CRC Press
Total Pages: 496
Release: 2006-06-12
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

The Dementias Book Excerpt:

The only guide to focus primarily on current molecular methods of diagnosis and early stage evaluation, this reference presents the latest techniques and technologies for dementia identification and evaluation, including neuropathological strategies, neuropsychological tests, biomarkers, CT, MRI, functional MRI, PET, and SPECT. Offering practical care and examination guidelines, each chapter provides findings that are particularly relevant for the assessment of disorders such as Alzheimer's disease, dementia with Lewy bodies, vascular dementia, and fronto-temporal dementia.

Neuroimaging biomarkers in Alzheimer s disease

Neuroimaging biomarkers in Alzheimer   s disease
Author: Samuel Barrack
Publsiher: iMedPub
Total Pages: 134
Release: 2013-10-20
ISBN: 1492274429
Category: Health & Fitness
Language: EN, FR, DE, ES & NL

Neuroimaging biomarkers in Alzheimer s disease Book Excerpt:

In view of the growing prevalence of AD worldwide, there is an urgent need for the development of better diagnostic tools and more effective therapeutic interventions. Indeed, much work in this field has been done during last decades. As such, a major goal of current clinical research in AD is to improve early detection of disease and presymptomatic detection of neuronal dysfunction, concurrently with the development of better tools to assess disease progression in this group of disorders. All these putative correlates are commonly referred to as AD-related biomarkers. The ideal biomarker should be easy to quantify and measure, reproducible, not subject to wide variation in the general population and unaffected by co- morbid factors. For evaluation of therapies, a biomarker needs to change linearly with disease progression and closely correlate with established clinico-pathological parameters of the disease. There is growing evidence that the use of biomarkers will increase our ability to better indentify the underlying biology of AD, especially in its early stages. These biomarkers will improve the detection of the patients suitable for research studies and drug trials, and they will contribute to a better management of the disease in the clinical practice. Indeed, much work in this field has been done during last decades. The vast number of important applications, combined with the untamed diversity of already identified biomarkers, show that there is a pressing need to structure the research made on AD biomarkers into a solid, comprehensive and easy to use tool to de deployed in clinical settings. To date there are few publications compiling results on this topic. That is why when I was asked to address this task I accepted inmediately. I am happy to present you a bundle of the best articles published about biomarkers for Alzheimer’s disease in recent times.

The Development of an Early Detection Method for Alzheimer s Disease Using H1 NMR Metabolomics

The Development of an Early Detection Method for Alzheimer s Disease Using H1 NMR Metabolomics
Author: Brittany L. Sumbler
Publsiher: Unknown
Total Pages: 28
Release: 2010
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

The Development of an Early Detection Method for Alzheimer s Disease Using H1 NMR Metabolomics Book Excerpt: