From Enzyme Models To Model Enzymes

Author by : Anthony John Kirby
Languange : en
Publisher by : Royal Society of Chemistry
Format Available : PDF, ePub, Mobi
Total Read : 68
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Description : This introduction to the exciting area of artificial enzymes is suitable for students and more senior researchers.


Design Of Enzymes And Enzyme Models

Author by : Robert A. Welch Foundation
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 96
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Enzyme Models And Enzyme Structure

Author by : Brookhaven National Laboratory. Symposium
Languange : en
Publisher by : Unknown
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Total Read : 29
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Nanozymes Next Wave Of Artificial Enzymes

Author by : Xiaoyu Wang
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 46
Total Download : 316
File Size : 45,9 Mb
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Description : This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.


Enzyme Mechanisms

Author by : Mike I. Page
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 93
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Description : Theories of enzyme catalysis. Enzyme models - synthetic polymers. Enzyme models - crown ethers. Enzyme models - cyclodextrins (cycloamyloses). Enzyme models - small molecule and intramolecular catalysis. Use of protein engineering to study enzyme mechanisms. Transition state affinity and the design of enzyme inhibitors. Acyl group transfer -fundamental mechanisms, cysteine proteinases, the serine proteinases, phosphoryl transfer, sulphotransferases and sulphatases, aspartic proteinases, metalloproteinases. Glycosil group transfer. Isomerization mechanisms through hydrogem and carbon transfer. Imine formation in enzimatic reactions. Pyridoxal phosphate dependent enzymes. Thiamine-depedent enzymes. Adenosylcobalamin-dependent enzymic reactions. Folate-dependent enzymes. Glutathione-dependent enzymes-chemistry. Glutathione-dependent enzymes - glutathione-S-transferases. Oxido-reductases - pyridine nucleotide-dependent enzymes. Oxido-reductases - flavoenzymes. Multi-enzyme complexes - Eukaryotic fatty acid synthases.


Understanding Enzymes

Author by : Allan Svendsen
Languange : en
Publisher by : CRC Press
Format Available : PDF, ePub, Mobi
Total Read : 82
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Description : Understanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the simulation work and nanotechnology measurement of enzymes in action in vitro or in silico. The book also presents new insights into the mechanistic function and understanding of enzyme reactions, as well as touching upon structural characteristics, including X-ray and nuclear magnetic resonance (NMR) structural methods. A major focus of the book is enzyme molecules’ dependency on dynamic and biophysical environmental impacts on their function in ensembles as well as single molecules. A wide range of readers, including academics, professionals, PhD and master’s students, industry experts, and chemists, will immensely benefit from this exclusive book.


Enzyme Kinetics And Mechanisms

Author by : Kenneth B. Taylor
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 44
Total Download : 396
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Description : Enzyme Kinetics and Mechanisms takes the reader through the experimental techniques and the logic by which the mechanisms of enzyme-catalyzed reactions can be elucidated by the results of steady-state kinetics and related experiments. It is meant to make these investigations both satisfying and effective. In distinction to other available descriptions, the descriptions in enzyme Kinetics and Mechanisms are limited to more commonly utilized and useful models and techniques. The logic relating the chemical models to the mathematical models and the logic of relating the mathematical models to data is presented in rather concise text, figures and equations. The development of mathematical models from chemical models is done by a unique algorithm that is both simple and quick, and the same concept are utilized to develop models for the effects of a variety of reaction conditions on the initial velocity. In addition, the various relationships of data, mathematical models and the chemical models is illustrated with examples from the scientific literature.


Enzyme Models And Enzyme Structure

Author by : Brookhaven National Laboratory. Biology Department
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 40
Total Download : 224
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Design Of Enzymes And Enzyme Models

Author by : Robert A. Welch Foundation
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 90
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File Size : 52,6 Mb
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Organic Nanoreactors

Author by : Samahe Sadjadi
Languange : en
Publisher by : Academic Press
Format Available : PDF, ePub, Mobi
Total Read : 55
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Description : Organic Nanoreactors: From Molecular to Supramolecular Organic Compounds provides a unique overview of synthetic, porous organic compounds containing a cavity which can encapsulate one or more guest(s). Confined space within a nanoreactor can isolate the guest(s) from the bulk and effectively influence the reaction inside the nanoreactor. Naturally occurring enzymes are compelling catalysts for selective reactions as their three-dimensional structures build up clefts, caves, or niches in which the active site is located. Additionally, reactive sites carrying special functional groups allow only specific reagents to react in a particular way, to lead to specific enantiomers as products. Equipped with suitable functional groups, then, nanoreactors form a new class of biomimetic compounds, which have multiple important applications in the synthesis of nanomaterials, catalysis, enzyme immobilization, enzyme therapy, and more. This book addresses various synthetic, organic nanoreactors, updating the previous decade of research and examining recent advances in the topic for the first comprehensive overview of this exciting group of compounds, and their practical applications. Bringing in the Editor’s experience in both academic research and industrial applications, Organic Nanoreactors focuses on the properties and applications of well-known as well as little-examined nanoreactor compounds and materials and includes brief overviews of synthetic routes and characterization methods. Focuses on organic nanoreactor compounds for greater depth Covers the molecular, supramolecular, and macromolecular perspectives Compiles previous and current sources from this growing field in one unique reference Provides brief overviews of synthetic routes and characterization methods


Enzyme Catalysis And Regulation

Author by : Gorden Hammes
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 9
Total Download : 253
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Description : Enzyme Catalysis and Regulation is an introduction to enzyme catalysis and regulation and covers topics ranging from protein structure and dynamics to steady-state enzyme kinetics, multienzyme complexes, and membrane-bound enzymes. Case studies of selected enzyme mechanisms are also presented. This book consists of 11 chapters and begins with a brief overview of enzyme structure, followed by a discussion on methods of probing enzyme structure such as X-ray crystallography and optical spectroscopy. Kinetic methods are then described, with emphasis on the general principles of steady-state and transient kinetics. The chemical principles involved in enzyme catalysis are also discussed, and case studies of a few well-documented enzymes are presented. The regulation of enzyme activity is analyzed from a nongenetic viewpoint, with particular reference to binding isotherms and models for allosterism. Two particular enzymes, aspartate transcarbamoylase and phosphofructokinase, are used as examples of well-studied regulatory enzymes. The last two chapters focus on multienzyme complexes and membrane-bound enzymes. This monograph is intended for graduate students, advanced undergraduates, and research workers in molecular biology and biochemistry.


Fungal Cellulolytic Enzymes

Author by : Xu Fang
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 57
Total Download : 467
File Size : 54,9 Mb
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Description : The book provides an overview of the current knowledge on cellulolytic enzymes and their applications. It summarizes the mechanisms of synthesis and hydrolysis of cellulolytic enzymes, industrial fungal strains, genetic engineering of fungal strains and application of cellulolytic enzymes. This book will be a useful reference for researchers and bioengineering experts engaged in lignocelluloses biodegradation, biomass utilization, enzyme production and fungal molecular biology.


Metal Chelates As Enzyme Models

Author by : Jon Erling Malmin
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 81
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Enzymatic Polymerization Towards Green Polymer Chemistry

Author by : Shiro Kobayashi
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 52
Total Download : 902
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Description : This book comprehensively covers researches on enzymatic polymerization and related enzymatic approaches to produce well-defined polymers, which is valuable and promising for conducting green polymer chemistry. It consists of twelve chapters, including the following topics: The three classes of enzymes, oxidoreductases, transferases and hydrolases, have been employed as catalysts for enzymatic polymerization and modification; Well-defined polysaccharides are produced by enzymatic polymerization catalyzed by hydrolases and transferases; Hydrolase-catalyzed polycondensation and ring-opening polymerization are disclosed to produce a variety of polyesters; Polyesters are synthesized by in-vivo acyltransferase catalysis produced by microorganisms; Enzymatic polymerization catalyzed by appropriate enzymes also produces polypeptides and other polymers; Poly(aromatic)s are obtained by enzymatic polymerization catalyzed by oxidoreductases and their model complexes; Such enzymes also induce oxidative polymerization of vinyl monomers; Enzymatic modification of polymers is achieved to produce functionalized polymeric materials; The enzymatic polymerization is a green process with non-toxic catalysts, high catalyst efficiency, green solvents and renewable starting materials, and minimal by-products; Moreover, renewable resources like biomass are potentially employed as a starting substrate, producing useful polymeric materials. This book is not only educative to young polymer chemists like graduate students but also suggestive to industrial researchers, showing the importance of the future direction of polymer synthesis for maintaining a sustainable society.


Comprehensive Supramolecular Chemistry

Author by : J. L. Atwood
Languange : en
Publisher by : Unknown
Format Available : PDF, ePub, Mobi
Total Read : 65
Total Download : 265
File Size : 49,8 Mb
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Description : This volume containing 15 chapters is practically classified into four parts. Part 1 deals with rapidly growing areas in bioorganic chemistry, covering antibody catalysis, structural aspects of DNA and DNA binding agents and protein mimetics. Part 2 describes receptor functions in relation to biochemical phenomena. Part 3 involves biomimetic reactions covering electron and energy transfer in supramolecular model systems, metalloporphyrin catalysis, zinc enzyme models and artificial enzymes with Vitamin B6 and B12 activity. Some aspects of enzyme chemistry are described in Part 4, covering kinetic, thermodynamic and supramolecular aspects of enzyme catalysis and site-directed mutagenesis of proteins.


Enzymatic And Model Carboxylation And Reduction Reactions For Carbon Dioxide Utilization

Author by : M. Aresta
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 10
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Description : The activation of carbon dioxide by transition metal complexes has been extensively studied. both experimentally and theoretically. 1 Central reactions in this chemistry are the insertion of C02 into M-X bonds. where X = H. C. 0. and N. (eq. 1-4). We are presently investigating the mechanistic aspects of these reaction processes and will herein deSCribe our current level of understanding. Comparisons of the pathway of the carbon-carbon bond fonning process in transition metal chemistry with the well known analogous chemistry involving organolithium reagents will be presented. Furthermore. the role of these reaction types in both homogeneous and heterogenous catalytic processes leading to useful chemicals will be elaborated. _OM> (1) lMt-H + ~ lMlopi _OM> (2) [Mt-R + C0. 2 [M]0. 2CR _OM> (3) [Mt-OR+ ~ [M]0. 2COR _OM> (4) [Mt-NR2 + C0. 2 [M]~CNR2 Insertion of C02 into the Metal-Hydride Bond. The reaction of anionic group 6 (Cr. Mo. W) transition metal hydrides with carbon dioxide to afford metalloformates occurs readlly at ambient temperature and 2 reduced pressures of carbon dioxide. This insertion process is referred to the normal pathway (Scheme 1). There are no documented cases of C02 insertion into the metal hydride bond to provide the alternative. metallocarboxylic acid. isomer (referred in Scheme 1 as abnormal). 3 Recent theoretical studies ascribe this preference to an unfavorable electrostatic interaction and poorer orbital overlap in the latter pro 4 cess. Nevertheless.


Enzymes And Coenzymes Advances In Research And Application 2011 Edition

Author by : Anonim
Languange : en
Publisher by : ScholarlyEditions
Format Available : PDF, ePub, Mobi
Total Read : 14
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File Size : 43,8 Mb
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Description : Enzymes and Coenzymes: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Enzymes and Coenzymes. The editors have built Enzymes and Coenzymes: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Enzymes and Coenzymes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Enzymes and Coenzymes: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Stability And Stabilization Of Enzymes

Author by : W.J.J. van den Tweel
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 73
Total Download : 125
File Size : 55,6 Mb
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Description : These proceedings contain most of the oral presentations and posters of the international symposium on Stability and Stabilization of Enzymes held in Maastricht in November 1992. They provide a comprehensive overview of the state-of-the-art in this field. The possible applications of enzymes are enormous. Years of development have seen many enzymes brought onto the market, but they are still expensive to use. Therefore, their efficient application is a prerequisite for common usage. One of the main factors for this efficiency is the stability of the enzymes. The topics thus ranged from the extensive fundamental thermodynamic knowledge gathered in academic research to the practical applied knowledge built up in industry during the time that enzymes have been produced commercially. The subject Stability and Stabilization of Enzymes was discussed from various points of view, as was reflected in the themes of the symposium sessions. In the session on Fundamentals of Enzyme Stabilisation the thermodynamic background of the phenomenon was highlighted. In yet another session, the recently developed analytical tools to measure enzyme stability and stabilisation were discussed. Further sessions comprised the physical, chemical and biological ways to obtain enzyme stabilisation and finally, the industrial practice of enzyme stabilisation was treated by representatives of the world's most important enzyme producers. The book will be of interest to researchers in universities and industry in the fields of biochemistry, enzymology and biotechnology.


Artificial Enzymes

Author by : Ronald Breslow
Languange : en
Publisher by : Wiley-VCH
Format Available : PDF, ePub, Mobi
Total Read : 56
Total Download : 249
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Description : This first book on this fascinating topic is edited by one of today's most famous and internationally respected organic chemists, renowned for his pioneering synthesis of the cyclopropenyl cation. For his part, Ronald Breslow has brought together leading scientists in this expanding area to provide a novel overview of protein-, cyclodextrin-, metal- and porphyrin-based artificial enzymes as well as enzyme-like polymers and dendrimers. A must for all scientists interested in this emerging field.


General Organic And Biological Chemistry

Author by : H. Stephen Stoker
Languange : en
Publisher by : Cengage Learning
Format Available : PDF, ePub, Mobi
Total Read : 18
Total Download : 530
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Description : Emphasizing the applications of chemistry and minimizing complicated mathematics, GENERAL, ORGANIC, AND BIOLOGICAL CHEMISTRY, 7E is written throughout to help students succeed in the course and master the biochemistry content so important to their future careers. The Seventh Edition's clear explanations, visual support, and effective pedagogy combine to make the text ideal for allied health majors. Early chapters focus on fundamental chemical principles while later chapters build on the foundations of these principles. Mathematics is introduced at point-of-use and only as needed. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.


Enzymes In The Environment

Author by : Richard G. Burns
Languange : en
Publisher by : CRC Press
Format Available : PDF, ePub, Mobi
Total Read : 43
Total Download : 383
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Description : The need to understand the biological processes that are important for essential aquatic and terrestrial ecosystem function has prompted much research into the field of ecological enzymology. This book presents the two broad areas of application in a compilation of reviews by 21 international experts in their respective fields. The first explores enzymatic activities to assess the processes or mechanisms that operate in a given system, such as the rhizosphere, plant leaves and shoots, soil surfaces, and biofilms. The second considers enzymes or microbial cells as sensors to detect microbial activity and stresses due to pollution, management, or climatic change in both aquatic and terrestrial ecosystems.