Description : The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. Utilizes a multidisciplinary approach Shows tricks and approaches not available in primary publications First volume of its kind to combine both methods of study for human aging and animal models Over 200 illustrations
Description : Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations
Description : A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008). The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers. This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology. * The most comprehensive source of up-to-date data on the neurobiology of aging, review articles cover: normal, sensory and cognitive aging; neuroendocrine, structural and molecular factors; and fully address both patholgy and intervention * Chapters represent an authoritative selection of relevant material from the most comprehensive source of information about neuroscience ever assembled, (Encyclopedia of Neuroscience), synthesizing information otherwise dispersed across a number of journal articles and book chapters, and saving researchers the time consuming process of finding and integrating this information themselves * Offering outstanding scholarship, each chapter is written by an expert in the topic area and over 20% of chapters feature international contributors, (representing 11 countries) * Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions * Fully explores various pathologies associated with the aging brain (Alzheimer's, dementia, Parkinson's, memory disorders, stroke, Down's syndrome, etc.) * Coverage of disorders and key interventions makes the volume relevant to clinicians as well as researchers * Heavily illustrated with over 100 color figures
Description : Animals have been used to model diseases or test new treatments since around 300 BC, and undoubtedly our ability to model disease in animals – including transgenic animals – has provided major breakthroughs in all fields of biomedical research. Due to their complexity and plurality of pathology and symptomatology, the study of neurodegenerative diseases relies heavily on animal models. These models have been developed in many species in the attempt to undercover the complex nature of the disease mechanisms involved. The ultimate goal is to test promising therapies and to manage, prevent or cure neurodegenerative disease. But because most animal models in this area do not reproduce the full phenotypical disease spectrum and the etiology and clinical presentation of neurodegenerative diseases differ from one patient to the next, the testing of these diseases in animal models often translates poorly to indices of efficacy when applied to the clinical population. Written by experts in the field with these advances and challenges in mind, this handbook provides an updated overview of the animal models being developed and used to study complex disease dynamics. The first part of the book presents an overview of animal models of various species and includes a review of new invertebrate animal models to study neurodegeneration. The second section presents the use of animal models to pinpoint disease mechanisms, and the last part of the handbook examines the various therapeutic interventions being used in models of neurodegenerative disease.
Description : This state-of-the-art handbook will keep researchers and practitioners in gerontology abreast of the newest theories and models of aging. With virtually all new contributors and content, this edition contains 35 chapters by the most highly respected luminaries in the field. It addresses theories and concepts built on cumulative knowledge in four disciplinary areas- biology, psychology, social sciences, and policy and practice- as well as landmark advances in trans-disciplinary science. With its explicit focus on theory, the handbook is unique in providing essential knowledge about primary explanations for aging, spanning from cells to societies. The chapters in the third edition place a strong emphasis on the future of theory development, assessing the current state of theories and providing a roadmap for how theory can shape research, and vice versa, in years to come. Many chapters also address connections between theories and policy or practice. Each set of authors has been asked to consider how theories in their area address matters of diversity and inequalities in aging, and how theories might be revised or tested with these matters in mind. The third edition also contains a new section, "Standing on the Shoulders of Giants," which includes personal essays by senior gerontologists who share their perspectives on the history of ideas in their fields, and on their experiences with the process and prospects of developing good theory. Hallmarks of the Third Edition: Highlights important gains in trans-disciplinary theories of aging Emphasizes the future of theory development Provides insights on theory development from living legends in gerontology Examines what human diversity and inequality mean for aging theories Emphasizes interconnections between theory, research, intervention, and policy Underscores international issues with greater representation of international authors Includes section introductions by the editors and associate editors that summarize theoretical developments Key Features: Highlights variability and diversity in aging processes, from the cellular level of biological aging to the societal level of public policy Provides insights on theory development from living legends in gerontology Offers intergenerational, interdisciplinary, and international perspectives Disseminates a forward-thinking, future-oriented focus in theory development
Description : "[This book] addresses issues on both sides of the Atlantic; examines the theoretical underpinnings of environmental gerontology...; and provides useful practical applications and guiding principles....Recommended."--Choice: Current Reviews for Academic Libraries The environments in which people live out their later lives have a strong impact on their identity and provide opportunities for nourishing social interactions. This volume translates the insights derived from contemporary research on residential environments and public spaces that enhance well-being into practical recommendations for the design of such beneficial community environments. The text is grounded in the conceptual and theoretical underpinnings of current research on place attachment, environmental meaning, and community living in later life. Emphasis is placed on how to design residential spaces that facilitate the development of a sense of place or home, and investigation is made into the kinds of lifestyles such spaces foster and support. A major theme pervading the text is the juxtaposition of private and public space. The book also addresses such themes as the transformation of spaces into places of personal identification and attachment, the need for shared intergenerational spaces, and consideration of diverse populations when designing public spaces. The book also considers how emerging public policy agendas affect the development and management of environments for the elderly. Environmental Gerontology includes the contributions of scholars in anthropology, architecture, economics, education, geography, gerontology, planning, psychology, sociology, and numerous health sciences, who hail from North America, Europe, and Asia. With its strong interdisciplinary focus, this text offers innovative and judicious recommendations for the creation of community environments that are truly beneficial for older adults. Key Features: Provides an up-to-date synthesis of the latest research on the meaning of place to older people and its relationship to well-being Offers fresh insight and critical perspectives on community planning and environmental design Considers private residences, retirement communities, long-term care facilities, and public and private community spaces Includes guiding principles for environmental design and practice relevant to the documented needs of older people Synthesizes contributions from international scholars in many disciplines
Description : Perimenopause has not been covered in the Obstetrics and Gynecology Clinics for over 10 years. This timely issue includes articles on BMI and its influence, Androgens, Cognition and Menopause, and Sexual Activity/Quality of Life.
Description : "Provides a unique perspective. I am particularly impressed with the sections on innovative design and methods to investigate cognitive aging and the integrative perspectives. None of the existing texts covers this material to the same level." —Donna J. La Voie, Saint Louis University "The emphasis on integrating the literature with theoretical and methodological innovations could have a far-reaching impact on the field." —Deb McGinnis, Oakland University The Handbook of Cognitive Aging: Interdisciplinary Perspectives clarifies the differences in patterns and processes of cognitive aging. Along with a comprehensive review of current research, editors Scott M. Hofer and Duane F. Alwin provide a solid foundation for building a multidisciplinary agenda that will stimulate further rigorous research into these complex factors. Key Features Gathers the widest possible range of perspectives by including cognitive aging experts in various disciplines while maintaining a degree of unity across chapters Examines the limitations of the extant literature, particularly in research design and measurement, and offers new suggestions to guide future research Highlights the broad scope of the field with topics ranging from demography to development to neuroscience, offering the most complete coverage available on cognitive aging
Description : "The authors of this book share decades of geriatric perioperative nursing care experience with readers in a thorough, systematic manner....[This book] would be an excellent addition to the library of any health care professional, especially a perioperative nurse, who provides care to older adults."--AORN Journal, the official publication of the Association of Perioperative Registered Nurses "This is a solid, well thought out book. The text has a clarity and focus which enhances understanding of the topics presented. It is particularly notable for crisp reading and uncomplicated, meaningful illustrations. Kudos to the authors for presenting such a medically solid book without losing the art of nursing care or the vision of a well tended patient."--Nursing News This timely volume introduces gerioperative care, a new model of surgical care for the elderly designed to improve surgical outcomes and prevent complications through a focus on communication and relationship-centered care. It is the only book to specifically address the care of older adults undergoing surgery, providing practitioners with critical, practical, and theoretical information from the initial decision to have surgery through the first follow-up visit post-discharge. The text includes the anatomy and physiology of aging, preoperative care, intraoperative and post-anesthesia care, postoperative care, returning home, risk appraisal, education, prevention, early intervention, multidisciplinary team collaboration, and effective communication across all systems of care. Gerioperative Nursing Care is an essential resource for students and practitioners of surgical, critical/acute care, and geriatric nursing, along with clinical and case managers. The tools presented help to sustain and enhance quality nursing care for older adults considering surgery, undergoing surgery, and during post-surgery visits. Key Features Presents a comprehensive new gerioperative care model for older adults undergoing surgery Follows patient from primary to follow up care, including hospital care, ambulatory care, emergency and elective surgery, and perioperative care Applies primary, secondary, and tertiary care concepts to surgery Presents innovative focus on case management, with new care guidelines Provides new applications in preoperative training, family coaching, and post-operative cognitive dysfunction prevention Describes how to make quality improvements in current surgical care practices Identifies and discusses major health problems of older adults through EBP Includes case studies with discussion questions
Description : The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.