Metastatic Disease Of The Nervous System Volume 149 Handbook Of Clinical Neurology

Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology

Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology

In this issue of Hematology/Oncology Clinics, guest editor David A. Reardon? brings his considerable expertise to the topic of Central Nervous System Malignancies. Top experts in the field cover key topics such as CNS Metastases, Leptomeningeal Disease, Neurofibromatoses, Imaging Advances for CNS Tumors, and more. Contains 16 relevant, practice-oriented topics including CNS Tumor Classification: An Update on the Integration of Tumor Genetics; Etiology and Epidemiology of CNS Tumors; The Evolving Role of Neurosurgical Intervention for CNS Tumor ; Update on Radiation Therapy for CNS Tumors; and more. Provides in-depth clinical reviews on CNS Malignancies, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Psychopharmacology of Neurologic Disease, Volume 165 in the Handbook of Clinical Neurology series, provides clinicians with an up-to-date, critical review of the best approaches to treatment of neurologic disease as discussed by experienced clinical investigators. The book is organized into sections on dementia, delirium, movement disorders, hereditary degenerative disease, epilepsy and psychogenic seizures, brain vascular disease, pseudobulbar affect, traumatic brain injury, neuro-oncology, multiple sclerosis and other demyelinating disorders, chronic fatigue syndrome/fibromyalgia, pain, headache, sleep disorders, autoimmune encephalitis/anti- NMDA encephalitis, functional sensory neurologic symptom disorders and neurodevelopmental disorders. Each of these diagnostic categories has a significant incidence of behavioral symptomatology that is secondary to the neurologic diagnosis that can serve to complicate other therapeutic interventions, alter the course of illness, and cause distress in patients and family caregivers. Provides a systematic, evidence-based compendium of best practices in the treatment of behavioral symptomatology relating to neurologic conditions Integrates state-of-the-art approaches in treating all behavioral symptomatology across all major neurologic disorders Explores psychopharmacological intervention, non-pharmacological strategies, behavioral symptomatology, and therapeutic interventions

This book provides a comprehensive overview of the management of brain and skull base tumors. It features detailed insight into the intrinsic molecular biology, anatomical foundation, radiological planning, surgical execution, and the novel therapeutics that guide today’s treatment regimens. The first section features concepts related to the epidemiology and pathological basis of disease processes, including relevant cellular and molecular biology. In the second section, integral anatomical foundations and principles are covered including microsurgical anatomy of the cerebrum, white matter tracts, ventricles, brainstem, skull base, advancements in radiological imaging, and cognitive examinations. Surgical approaches and how to execute these procedures are then subsequently discussed in the third part of the work. Principles of Neuro-Oncology: Brain & Skull Base is a practically applicable guide to the latest treatment techniques available to treat these patients. Therefore, it is an indispensable resource for all physicians who utilize these methodologies in their day-to-day practice.

Clinical Neurophysiology: Diseases and Disorders, the latest release in the Handbook of Clinical Neurology series, reviews the current practice of clinical neurophysiology in the laboratory, by the bedside, and in the operating room or intensive care unit. The volume is organized into sections focused on diseases of the central and peripheral nervous systems, sleep disorders, and autonomic disorders. Among the CNS topics covered are epilepsy, altered states of consciousness, disorders of cognition, brain death, demyelinating diseases, stroke, pain, movement disorders, vestibular disease, and auditory disorders. Peripheral nervous system topics include focal mononeuropathies, generalized polyneuropathies, muscle diseases, hyperexcitability states, neuromuscular junction disorders, anterior horn cells diseases, and cranial neuropathies. There are also chapters on sleep apneas, hypersomnias, parasomnias, and circadian rhythm disorders. Autonomic topics include primary autonomic failure, multisystem atrophy, and postural orthostatic tachycardia syndrome. Provides an up-to-date review on the practice of the neurophysiological techniques used in the assessment of neurological diseases Explores the electrophysiological techniques used to better understand neurological function and dysfunction of the central and peripheral nervous systems Discusses monitoring neurologic function in the intensive care unit and the assessment of suspected brain death Includes discussions of various newer techniques, including functional brain mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

Cingulate Cortex, Volume 166 summarizes research on the cingulate cortex, including its structure and function in health and how it is compromised in disease or trauma. Chapters discuss the cingulate organization by region and area, cover its function in consciousness, attention, social cognition and spatial orientation, review neurological disorders with cingulate involvement, including neurodegenerative disorders, movement disorders, Parkinson’s, ADHD, Cognitive impairment, Palsy, Tourette’s Syndrome, chronic pain, seizures, and more. Final sections discuss the relationship between the cingulate cortex, stress and psychiatric disorders. Coverage here includes PTSD, anxiety, depression, and evidence-based treatment for same. Identifies the structure and function of all areas and regions of the cingulate cortex Discusses its role in sensory-motor, cognitive and emotional processing Covers cingulate-mediated neurological and psychiatric disorders Supplies evidence-based treatment for cingulate mediated disorders

The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases Explores long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseases Features chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases

Disorders of Emotion in Neurologic Disease, Volume 183 in the Handbook of Clinical Neurology Series, informs clinicians on which neurologic diseases are likely to have a secondary effect on emotion, what to look for in diagnosis, and best practices for treatment. The book begins with an understanding of the neurological basis for emotions in order to better understand what goes awry in neurological disease. It then discusses specific neurologic diseases and disorders affecting emotion. Reviews the neurology of emotions Specifies neurologic diseases that affect emotional expression Informs clinicians on how to diagnose, along with best practices for treatment Includes coverage of stroke, dementia, epilepsy, Huntington's, Parkinson's, TBI, and more

Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology. Provides an up-to-date review on the practice of neurophysiological techniques in the assessment of neurological disease Explores the electrophysiological techniques used to better understand neurological function and dysfunction, first in the area of consciousness and epilepsy, then in the areas of the peripheral nervous system and sleep Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

Neonatal Neurology, Volume 162 in the Handbook of Clinical Neurology, series updates the reader on the latest advances in the study of neurological diseases diagnosed in the fetal and neonatal periods. With recent advances in magnetic resonance imaging, digital electroencephalography recording, and genetic testing and diagnosis, there is expanding awareness relating to early onset neurological conditions and how their early diagnosis can improve prediction of outcome and subsequent neurodevelopmental outcome. This new volume covers diagnosis and management of congenital conditions, including brain malformations, neuromuscular conditions and genetic epilepsies, as well as acquired injury related to peri-partum events, prematurity, critical illness and systemic diseases. Provides an in-depth understanding of the basic scientific research, translational research and clinical consensus across neonatal and fetal medicine Explores how early neurological diagnosis can improve prediction of outcome and how management can improve subsequent neurodevelopmental outcome Features chapters co-authored by two experts, combining expertise in both neonatal and fetal neurology

Brain-Computer Interfacing, Volume 168, not only gives readers a clear understanding of what BCI science is currently offering, but also describes future expectations for restoring lost brain function in patients. In-depth technological chapters are aimed at those interested in BCI technologies and the nature of brain signals, while more comprehensive summaries are provided in the more applied chapters. Readers will be able to grasp BCI concepts, understand what needs the technologies can meet, and provide an informed opinion on BCI science. Explores how many different causes of disability have similar functional consequences (loss of mobility, communication etc.) Addresses how BCI can be of use Presents a multidisciplinary review of BCI technologies and the opportunities they provide for people in need of a new kind of prosthetic Offers a comprehensive, multidisciplinary review of BCI for researchers in neuroscience and traumatic brain injury that is also ideal for clinicians in neurology and neurosurgery

Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders. Covers all aspects of disorders of taste and smell for beginning students of various disciplines (neurology, psychiatry, neuropsychology, otolaryngology) Teaches that smell and taste testing can be useful in differential diagnosis and can assess brain regions not normally assessed by traditional neurological or neuropsychological tests Addresses, in detail, recent evidence that smell loss is a better predictor of future mortality than dementia and even heart disease

The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more. Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders. Provides an overview of the structure, function, disorder and rehabilitation of the frontal lobes Addresses a wide variety of methodologies – from genetics and molecular biology, to optogenetics and hi-res fMRI, and more Contains content of interest to advanced students, junior researchers and clinicians getting involved in research Features the input of leaders in neuroanatomical research from around the globe – the broadest, most expert coverage available

Meningiomas, Volume 170, Part Two, discusses tumors that arise from the coverings of the brain and spinal cord. In this updated volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons, provide up-to-date synopses of each topic as it relates directly to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments. This book serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type, hence the greatest challenge of treatment is the need to complete tumor removal without creating new neurologic deficit. Provides current reviews of neurosurgical issues, such as endoscopic surgery, molecular biology of meningiomas, and the role of different radiation oncology treatment modalities and drug therapies Addresses multiple patient populations – children, elderly and those with multiple or radiation-induced tumor Offers a strong focus on anatomy and surgical approaches Edited work featuring leaders in neurosurgery and neuro-oncology around the globe – the broadest, most expert coverage available

Meningiomas, Volume 169, Part One, serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type. In this volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons - have provided up-to-date synopses of each topic as it relates to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments. Provides current reviews of neurosurgical issues, such as endoscopic surgery, molecular biology of meningiomas, and the role of different radiation oncology treatment modalities and drug therapies Addresses multiple patient populations – children, elderly and those with multiple or radiation-induced tumors Offers a strong focus on anatomy and surgical approaches Features leaders in neurosurgery and neuro-oncology from around the globe – the broadest, most expert coverage available

Neurology and Pregnancy provides a comprehensive multidisciplinary guide to best practices for research and practicing neurologists, as well as obstetricians and other specialists caring for women with an acute or chronic neurological disorder. The book encompasses preconception care, genetic counseling, pregnancy in patients with chronic neurological disorders, and acute pregnancy-related neurological complications. Postpartum care and complications, including lactation concerns, are also addressed, as well as the long-term effects of pregnancy and its complications on maternal brain health. Vol 1 summarizes the complex neurophysiological changes in pregnancy from a basic and translational science perspective. This includes neuroimaging, principles of neuro-obstetric critical care, and ethical and medicolegal concerns, describes normal fetal cerebral development and summarizes the management of the most common prenatal neurological diagnoses. Vol 2 focuses on chronic neurological conditions in pregnancy such as epilepsy, migraine, and multiple sclerosis, as well as acute neurological disorders including preeclampsia/ eclampsia, ischemic and hemorrhagic stroke, and CNS infections. Each chapter introduction includes data on epidemiology, when applicable. In discussing management, comments of safety profiles of medications preconceptionally, during pregnancy and lactation are summarized. Each chapter includes 1-2 illustrative cases. Discusses neuroendocrine, brain, PNS, and cerebro-vascular changes in pregnancy Includes neurological care of the pregnant patient Covers neuroimaging and monitoring techniques Reviews common neurological complications with pregnancy Supplies illustrative case study examples

The Cerebellum: From Embryology to Diagnostic Investigations, Volume 154 is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: Neuroimaging, and includes content on conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders). Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases Explores the long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseases Features chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases

Neurology of Vision and Visual Disorders, Volume 178 in the Handbooks of Neurology series provides comprehensive summaries of recent research on the brain and nervous system. This volume reviews alterations in vision that stem from the retina to the cortex. Coverage includes content on vision and driving derived from the large amount of time devoted in clinics to determining who is safe to drive, along with research on the interplay between visual loss, attention and strategic compensations that may determine driving suitability. The title concludes with vision therapies and the evidence behind these approaches. Each chapter is co-written by a basic scientist collaborating with a clinician to provide a solid underpinning of the mechanisms behind the clinical syndromes. Reviews the neurological underpinnings of visual perception disorders Encompasses the cortex to the retina Covers functional organization, electrophysiology and subcortical visual pathways Discusses assessment, diagnosis and management of visual perception disorders Includes international experts from Australia, Canada, Denmark, Germany, Singapore, and the UK and US