Microfluidics for Cellular Applications

Microfluidics for Cellular Applications
Author: Gerardo Perozziello,Ulrich Kruhne,Paola Luciani
Publsiher: Elsevier
Total Pages: 352
Release: 2022-07-01
ISBN: 0128224975
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Microfluidics for Cellular Applications Book Excerpt:

Microfluidics for Cellular Applications describes microfluidic devices for cell screening from a physical, technological and applications point-of-view, presenting a comparison with the cell microenvironment and conventional instruments used in medicine. Microfluidic technologies, protocols, devices for cell screening and treatment have reached an advanced state but are mainly used in research. Sections break them down into practical applications and conventional medical procedures and offers insights and analysis on how higher resolutions and fast operations can be reached. This is an important resource for those from an engineering and technology background who want to understand more and gain additional insights on cell screening processes. Outlines the major applications of microfluidic devices in medicine and biotechnology Assesses the major challenges of using microfluidic devices in terms of complexity of the control set-up, ease of use, integration capability, automation level, analysis throughput, content and costs Describes the major fabrication techniques for assembling effective microfluidic devices for bioapplications

Microfluidics for Biological Applications

Microfluidics for Biological Applications
Author: Wei-Cheng Tian,Erin Finehout
Publsiher: Springer Science & Business Media
Total Pages: 416
Release: 2009-03-02
ISBN: 0387094806
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Microfluidics for Biological Applications Book Excerpt:

Microfluidics for Biological Applications provides researchers and scientists in the biotechnology, pharmaceutical, and life science industries with an introduction to the basics of microfluidics and also discusses how to link these technologies to various biological applications at the industrial and academic level. Readers will gain insight into a wide variety of biological applications for microfluidics. The material presented here is divided into four parts, Part I gives perspective on the history and development of microfluidic technologies, Part II presents overviews on how microfluidic systems have been used to study and manipulate specific classes of components, Part III focuses on specific biological applications of microfluidics: biodefense, diagnostics, high throughput screening, and tissue engineering and finally Part IV concludes with a discussion of emerging trends in the microfluidics field and the current challenges to the growth and continuing success of the field.

Biological Applications of Microfluidics

Biological Applications of Microfluidics
Author: Frank A. Gomez
Publsiher: John Wiley & Sons
Total Pages: 517
Release: 2008-02-15
ISBN: 0470074833
Category: Science
Language: EN, FR, DE, ES & NL

Biological Applications of Microfluidics Book Excerpt:

Microfluidics-today's applications and tomorrow's potential Microfluidics has facilitated major biochemical application advancements in point-of-care diagnostics, bioterrorism detection, and drug discovery. There are numerous potential applications in biotechnology, pharmaceuticals, the life sciences, defense, public health, and agriculture. Microfluidic lab-on-a-chip (LOC) technologies represent a revolution in laboratory experimentation, bringing the benefits of miniaturization, integration, and automation to many research-based industries. Biological Applications of Microfluidics details recent advances in the biological applications of microfluidics, including cell sorting, DNA sequencing on a chip, microchip capillary electrophoresis, and synthesis on a microfluidic format. After an overview of microfluidics highlighting recent seminal works, it includes multiple chapters on: * Cell analysis on microfluidic devices * Chemical (enzymatic and non-enzymatic) reactions on microchips * Separations on microchips * Biomedical applications of microfluidics * Microfluidic fabrication * Hybrid microfluidic applications Microfluidics has incredible potential in a variety of areas. This book covers many recent advances, including microfabricated LOC technologies, advanced microfluidic tools, microfluidic culture platforms for stem cell and neuroscience research, a novel application of microfluidic LOC devices that facilitates fundamental research in proteomics that cannot be performed without miniaturization, the nano fountain pen, and more. With contributions from leading experts in chemistry, physics, bioengineering, material science, biomedicine, and other fields plus references at the end of each chapter to facilitate further study, this is an all-in-one, hands-on resource for analytical chemists and researchers. It is also an excellent resource for students studying analytical chemistry or biotechnology.

Fabrication of Microfluidic Devices and Their Applications in Chemical and Cellular Researches

Fabrication of Microfluidic Devices and Their Applications in Chemical and Cellular Researches
Author: Yizhe Zheng
Publsiher: Unknown
Total Pages: 117
Release: 2011
ISBN: 1928374650XXX
Category: Biochips
Language: EN, FR, DE, ES & NL

Fabrication of Microfluidic Devices and Their Applications in Chemical and Cellular Researches Book Excerpt:

Open Space Microfluidics

Open Space Microfluidics
Author: Emmanuel Delamarche,Govind V. Kaigala
Publsiher: John Wiley & Sons
Total Pages: 440
Release: 2018-01-18
ISBN: 3527696806
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Open Space Microfluidics Book Excerpt:

Summarizing the latest trends and the current state of this research field, this up-to-date book discusses in detail techniques to perform localized alterations on surfaces with great flexibility, including microfluidic probes, multifunctional nanopipettes and various surface patterning techniques, such as dip pen nanolithography. These techniques are also put in perspective in terms of applications and how they can be transformative of numerous (bio)chemical processes involving surfaces. The editors are from IBM Zurich, the pioneers and pacesetters in the field at the forefront of research in this new and rapidly expanding area.

Microfluidic Chip Applications in Cellular Studies

Microfluidic Chip Applications in Cellular Studies
Author: Hsing-Yun Sharon Hsu
Publsiher: Unknown
Total Pages: 130
Release: 2008
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Microfluidic Chip Applications in Cellular Studies Book Excerpt:

Cell Analysis on Microfluidics

Cell Analysis on Microfluidics
Author: Jin-Ming Lin
Publsiher: Springer
Total Pages: 429
Release: 2017-10-25
ISBN: 9811053944
Category: Science
Language: EN, FR, DE, ES & NL

Cell Analysis on Microfluidics Book Excerpt:

This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.

Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications
Author: Xiujun James Li,Yu Zhou
Publsiher: Woodhead Publishing
Total Pages: 722
Release: 2021-08-09
ISBN: 0128227559
Category: Medical
Language: EN, FR, DE, ES & NL

Microfluidic Devices for Biomedical Applications Book Excerpt:

Microfluidic Devices for Biomedical Applications, Second Edition provides updated coverage on the fundamentals of microfluidics, while also exploring a wide range of medical applications. Chapters review materials and methods, microfluidic actuation mechanisms, recent research on droplet microfluidics, applications in drug discovery and controlled-delivery, including micro needles, consider applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds, and cover the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. This book is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Details applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and its role in developing tissue scaffolds, and stem cell engineering

Microfluidics and Bio MEMS

Microfluidics and Bio MEMS
Author: Tuhin S. Santra
Publsiher: CRC Press
Total Pages: 548
Release: 2020-11-01
ISBN: 1000769135
Category: Medical
Language: EN, FR, DE, ES & NL

Microfluidics and Bio MEMS Book Excerpt:

The past two decades have seen rapid development of micro-/nanotechnologies with the integration of chemical engineering, biomedical engineering, chemistry, and life sciences to form bio-MEMS or lab-on-chip devices that help us perform cellular analysis in a complex micro-/nanoflluidic environment with minimum sample consumption and have potential biomedical applications. To date, few books have been published in this field, and researchers are unable to find specialized content. This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS devices. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. In addition, it elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-nanoelectromechanical systems (bio-NEMS), biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical micro-/nanodevices. Readers can gain knowledge of different aspects of microfluidics and bio-MEMS devices; their design, fabrication, and integration; and biomedical applications. The book will also help biotechnology-based industries, where research and development is ongoing in cell-based analysis, diagnosis, and drug screening.

Encyclopedia of Spectroscopy and Spectrometry

Encyclopedia of Spectroscopy and Spectrometry
Author: Anonim
Publsiher: Academic Press
Total Pages: 3584
Release: 2016-09-22
ISBN: 0128032251
Category: Science
Language: EN, FR, DE, ES & NL

Encyclopedia of Spectroscopy and Spectrometry Book Excerpt:

This third edition of the Encyclopedia of Spectroscopy and Spectrometry provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas

Microfluidics in Cell BiologyPart A Microfluidics for multicellular systems

Microfluidics in Cell BiologyPart A  Microfluidics for multicellular systems
Author: Anonim
Publsiher: Academic Press
Total Pages: 273
Release: 2018-07-20
ISBN: 0128142812
Category: Science
Language: EN, FR, DE, ES & NL

Microfluidics in Cell BiologyPart A Microfluidics for multicellular systems Book Excerpt:

Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids, Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chip for pharmacokinetic analysis, Cancer immunotherapy on chips, and more. Contains contributions from experts in the field from across the globe Covers a wide array of topics on both mitosis and meiosis Includes relevant, analysis based topics

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip Advances in Organs on a Chip and Organoids Technologies

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip  Advances in Organs on a Chip and Organoids Technologies
Author: Qasem Ramadan,Massimo Alberti,Martin Dufva,Yi-Chung Tung
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2019-10-16
ISBN: 2889631141
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip Advances in Organs on a Chip and Organoids Technologies Book Excerpt:

Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific disciplines with industrial and clinical applications. In particular, organotypic cell culture and its integration in microfluidic devices would enable the realization of “in vivo-like” cell microenvironment within systems that are more amenable to automation and integration. Such remarkable advancement forms the foundation and motivation to transfer research from the laboratory to the field. Although the microfluidics and cell culture technologies have influenced many areas of science, significant research efforts are currently focus on finding methods to transform drug screening and toxicity testing from a system reliant on high-dose animal studies to one based primarily on human-relevant in vitro models. In line with regulatory developments precluding the use of animal testing, as well as fundamental differences in animal versus human, human in vitro methodologies are required to replace the animal-based testes while permitting physiologically relevant model equivalents for superior prediction. Organs-on-a-chip is an ambitious and rapidly growing technology that promise to bridge the gap between in vivo and in vitro studies and open wide possibilities in medical and industrial applications. However, many challenges are still ahead. This eBook present recent state-of-the-art works and critical reviews in organs-on-a-chip technology which highlight the new advances in this growing field with an emphasis on the interface between technological advancements and high impact applications.

Microfluidic Technologies for Human Health

Microfluidic Technologies for Human Health
Author: Utkan Demirci,Robert Langer
Publsiher: World Scientific
Total Pages: 478
Release: 2012
ISBN: 9814405523
Category: Medical
Language: EN, FR, DE, ES & NL

Microfluidic Technologies for Human Health Book Excerpt:

The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves steps from biological sample/analyte loading to storage, detection, and analysis. The chapters collected in this book detail recent advances in these processes using microfluidic devices and systems. The reviews of portable devices for diagnostic purposes are likely to evoke interest and raise new research questions in interdisciplinary fields (e.g., efficient MEMS/microfluidic engineering driven by biological and medical applications).The variety of the selected topics (general relevance of microfluidics in medical and bioengineering research, fabrication, advances in on-chip sample detection and analysis, and specific disease models) ensures that each of them can be viewed in the larger context of microfluidic-mediated diagnostics.

Biomedical Applications of Microfluidic Devices

Biomedical Applications of Microfluidic Devices
Author: Michael R. Hamblin,Mahdi Karimi
Publsiher: Academic Press
Total Pages: 350
Release: 2020-11-12
ISBN: 0128187921
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Biomedical Applications of Microfluidic Devices Book Excerpt:

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Applications of Microfluidic Systems in Biology and Medicine

Applications of Microfluidic Systems in Biology and Medicine
Author: Manabu Tokeshi
Publsiher: Springer
Total Pages: 382
Release: 2019-04-25
ISBN: 9811362297
Category: Science
Language: EN, FR, DE, ES & NL

Applications of Microfluidic Systems in Biology and Medicine Book Excerpt:

This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field —undergraduates, engineers, biologists, medical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.

Microfluidics for Pharmaceutical Applications

Microfluidics for Pharmaceutical Applications
Author: Helder A. Santos,Dongfei Liu,Hongbo Zhang
Publsiher: William Andrew
Total Pages: 495
Release: 2018-10-12
ISBN: 0128126604
Category: Science
Language: EN, FR, DE, ES & NL

Microfluidics for Pharmaceutical Applications Book Excerpt:

Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications. Presents detailed coverage on the fabrication of novel drug delivery systems with desired characteristics, such as uniform size, Janus particles, and particular or combined responsiveness Includes a variety of case studies that explain principles Focuses on commercialization, cost, safety, society and educational issues of microfluidic applications, showing how microfluidics is used in the real world

Microfluidics in Cell Biology Part C Microfluidics for Cellular and Subcellular Analysis

Microfluidics in Cell Biology Part C  Microfluidics for Cellular and Subcellular Analysis
Author: Anonim
Publsiher: Academic Press
Total Pages: 264
Release: 2018-11-22
ISBN: 0128142855
Category: Science
Language: EN, FR, DE, ES & NL

Microfluidics in Cell Biology Part C Microfluidics for Cellular and Subcellular Analysis Book Excerpt:

Microfluidics in Cell Biology Part C, Volume 148, a new release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are three sections on microfluidics in various multi-cellular models, including microfluidics in cell monolayers/spheroids, microfluidics in organ on chips, and microfluidics in model organisms. Specific chapters discuss collective migration in microtubes, leukocyte adhesion dynamics on endothelial monolayers under flow, constrained spheroid for perfusion culture, cells in droplet arrays, heart on chips, kidney on chips, liver on chips, and more. Contains contributions from experts in the field from across the world Covers a wide array of topics on both mitosis and meiosis Includes relevant, analysis based topics

Microfluidics and Nanofluidics Handbook

Microfluidics and Nanofluidics Handbook
Author: Sushanta K. Mitra,Suman Chakraborty
Publsiher: CRC Press
Total Pages: 1132
Release: 2011-09-20
ISBN: 1439816778
Category: Science
Language: EN, FR, DE, ES & NL

Microfluidics and Nanofluidics Handbook Book Excerpt:

The Microfluidics and Nanofluidics Handbook: Two-Volume Set comprehensively captures the cross-disciplinary breadth of the fields of micro- and nanofluidics, which encompass the biological sciences, chemistry, physics and engineering applications. To fill the knowledge gap between engineering and the basic sciences, the editors pulled together key individuals, well known in their respective areas, to author chapters that help graduate students, scientists, and practicing engineers understand the overall area of microfluidics and nanofluidics. Topics covered include Cell Lysis Techniques in Lab-on-a-Chip Technology Electrodics in Electrochemical Energy Conversion Systems: Microstructure and Pore-Scale Transport Microscale Gas Flow Dynamics and Molecular Models for Gas Flow and Heat Transfer Microscopic Hemorheology and Hemodynamics Covering physics and transport phenomena along with life sciences and related applications, Volume One: Chemistry, Physics, and Life Science Principles provides readers with the fundamental science background that is required for the study of microfluidics and nanofluidics. Both volumes include as much interdisciplinary knowledge as possible to reflect the inherent nature of this area, valuable to students and practitioners.

Microfluidics and Nanofluidics Handbook Two Volume Set

Microfluidics and Nanofluidics Handbook  Two Volume Set
Author: Sushanta K. Mitra,Suman Chakraborty
Publsiher: CRC Press
Total Pages: 1766
Release: 2011-09-20
ISBN: 1466515740
Category: Science
Language: EN, FR, DE, ES & NL

Microfluidics and Nanofluidics Handbook Two Volume Set Book Excerpt:

The Microfluidics and Nanofluidics Handbook: Two-Volume Set comprehensively captures the cross-disciplinary breadth of micro- and nanofluidics, which encompass the biological sciences, chemistry, physics and engineering applications. To fill the knowledge gap between engineering and the basic sciences, the editors pulled together key individuals, w

Computational and Experimental Fluid Mechanics with Applications to Physics Engineering and the Environment

Computational and Experimental Fluid Mechanics with Applications to Physics  Engineering and the Environment
Author: Leonardo Di G. Sigalotti,Jaime Klapp,Eloy Sira
Publsiher: Springer Science & Business Media
Total Pages: 554
Release: 2014-01-11
ISBN: 3319001914
Category: Science
Language: EN, FR, DE, ES & NL

Computational and Experimental Fluid Mechanics with Applications to Physics Engineering and the Environment Book Excerpt:

The book presents a collection of selected papers from the I Workshop of the Venezuelan Society of Fluid Mechanics held on Margarita Island, Venezuela from November 4 to 9, 2012. Written by experts in their respective fields, the contributions are organized into five parts: - Part I Invited Lectures, consisting of full-length technical papers on both computational and experimental fluid mechanics covering a wide range of topics from drops to multiphase and granular flows to astrophysical flows, - Part II Drops, Particles and Waves - Part III Multiphase and Multicomponent Flows - Part IV Atmospheric and Granular Flows - and Part V Turbulent and Astrophysical Flows. The book is intended for upper-level undergraduate and graduate students as well as for physicists, chemists and engineers teaching and working in the field of fluid mechanics and its applications. The contributions are the result of recent advances in theoretical and experimental research in fluid mechanics, encompassing both fundamentals as well as applications to fluid engineering design, including pipelines, turbines, flow separators, hydraulic systems and biological fluid elements, and to granular, environmental and astrophysical flows.