Multiscale Models In Mechano And Tumor Biology

Author by : Alf Gerisch
Languange : en
Publisher by : Springer
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Total Read : 76
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Description : This book presents and discusses the state of the art and future perspectives in mathematical modeling and homogenization techniques with the focus on addressing key physiological issues in the context of multiphase healthy and malignant biological materials. The highly interdisciplinary content brings together contributions from scientists with complementary areas of expertise, such as pure and applied mathematicians, engineers, and biophysicists. The book also features the lecture notes from a half-day introductory course on asymptotic homogenization. These notes are suitable for undergraduate mathematics or physics students, while the other chapters are aimed at graduate students and researchers.


Multiscale Modeling In Biomechanics And Mechanobiology

Author by : Suvranu De
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 31
Total Download : 552
File Size : 48,8 Mb
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Description : Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.


The Mathematics Of Mechanobiology

Author by : Antonio DeSimone
Languange : en
Publisher by : Springer Nature
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Total Read : 31
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Description : This book presents the state of the art in mathematical research on modelling the mechanics of biological systems – a science at the intersection between biology, mechanics and mathematics known as mechanobiology. The book gathers comprehensive surveys of the most significant areas of mechanobiology: cell motility and locomotion by shape control (Antonio DeSimone); models of cell motion and tissue growth (Benoît Perthame); numerical simulation of cardiac electromechanics (Alfio Quarteroni); and power-stroke-driven muscle contraction (Lev Truskinovsky). Each section is self-contained in terms of the biomechanical background, and the content is accessible to all readers with a basic understanding of differential equations and numerical analysis. The book disentangles the phenomenological complexity of the biomechanical problems, while at the same time addressing the mathematical complexity with invaluable clarity. The book is intended for a wide audience, in particular graduate students and applied mathematicians interested in entering this fascinating field.


Constitutive Modelling Of Solid Continua

Author by : José Merodio
Languange : en
Publisher by : Springer Nature
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Total Read : 28
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Description : This volume consists of a collection of chapters by recognized experts to provide a comprehensive fundamental theoretical continuum treatment of constitutive laws used for modelling the mechanical and coupled-field properties of various types of solid materials. It covers the main types of solid material behaviour, including isotropic and anisotropic nonlinear elasticity, implicit theories, viscoelasticity, plasticity, electro- and magneto-mechanical interactions, growth, damage, thermomechanics, poroelasticity, composites and homogenization. The volume provides a general framework for research in a wide range of applications involving the deformation of solid materials. It will be of considerable benefit to both established and early career researchers concerned with fundamental theory in solid mechanics and its applications by collecting diverse material in a single volume. The readership ranges from beginning graduate students to senior researchers in academia and industry.


Leveraging Distortions

Author by : Collin Rice
Languange : en
Publisher by : MIT Press
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Total Read : 63
Total Download : 978
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Description : An examination of how scientists deliberately and justifiably use pervasive distortions of relevant features to explain and understand natural phenomena. A fundamental rule of logic is that in order for an argument to provide good reasons for its conclusion, the premises of the argument must be true. In this book, Collin Rice shows how the practice of science repeatedly, pervasively, and deliberately violates this principle. Rice argues that scientists strategically use distortions that misrepresent relevant features of natural phenomena in order to explain and understand--and that they use these distortions deliberately and justifiably in order to discover truths that would be otherwise inaccessible. Countering the standard emphasis on causation, accurate representation, and decomposition of science into its accurate and inaccurate parts, Rice shows that science's epistemic achievements can still be factive despite their being produced through the use of holistically distorted scientific representations. Indeed, he argues, this distortion is one of the most widely employed and fruitful tools used in scientific theorizing. Marshalling a range of case studies, Rice contends that many explanations in science are noncausal, and he presents an alternate view of explanation that captures the variety of noncausal explanations found across the sciences. He proposes an alternative holistic distortion view of idealized models, connecting it to physicists' concept of a universality class; shows how universality classes can overcome some of the challenges of multiscale modeling; and offers accounts of explanation, idealization, modeling, and understanding.


Scientific Computing

Author by : John A. Trangenstein
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 69
Total Download : 118
File Size : 41,9 Mb
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Description : This is the second of three volumes providing a comprehensive presentation of the fundamentals of scientific computing. This volume discusses more advanced topics than volume one, and is largely not a prerequisite for volume three. This book and its companions show how to determine the quality of computational results, and how to measure the relative efficiency of competing methods. Readers learn how to determine the maximum attainable accuracy of algorithms, and how to select the best method for computing problems. This book also discusses programming in several languages, including C++, Fortran and MATLAB. There are 49 examples, 110 exercises, 66 algorithms, 24 interactive JavaScript programs, 77 references to software programs and 1 case study. Topics are introduced with goals, literature references and links to public software. There are descriptions of the current algorithms in LAPACK, GSLIB and MATLAB. This book could be used for a second course in numerical methods, for either upper level undergraduates or first year graduate students. Parts of the text could be used for specialized courses, such as nonlinear optimization or iterative linear algebra.


Meshfree Methods For Partial Differential Equations Ix

Author by : Michael Griebel
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 41
Total Download : 167
File Size : 41,9 Mb
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Description : This volume collects selected papers presented at the Ninth International Workshop on Meshfree Methods held in Bonn, Germany in September 2017. They address various aspects of this very active research field and cover topics from applied mathematics, physics and engineering. The numerical treatment of partial differential equations with meshfree discretization techniques has been a very active research area in recent years. While the fundamental theory of meshfree methods has been developed and considerable advances of the various methods have been made, many challenges in the mathematical analysis and practical implementation of meshfree methods remain. This symposium aims to promote collaboration among engineers, mathematicians, and computer scientists and industrial researchers to address the development, mathematical analysis, and application of meshfree and particle methods especially to multiscale phenomena. It continues the 2-year-cycled Workshops on Meshfree Methods for Partial Differential Equations.


Exercises In Numerical Linear Algebra And Matrix Factorizations

Author by : TOM. MUNTINGH LYCHE (GEORG. RYAN, OYVIND.)
Languange : en
Publisher by : Unknown
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Total Read : 99
Total Download : 482
File Size : 46,5 Mb
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Description : To put the world of linear algebra to advanced use, it is not enough to merely understand the theory; there is a significant gap between the theory of linear algebra and its myriad expressions in nearly every computational domain. To bridge this gap, it is essential to process the theory by solving many exercises, thus obtaining a firmer grasp of its diverse applications. Similarly, from a theoretical perspective, diving into the literature on advanced linear algebra often reveals more and more topics that are deferred to exercises instead of being treated in the main text. As exercises grow more complex and numerous, it becomes increasingly important to provide supporting material and guidelines on how to solve them, supporting students' learning process. This book provides precisely this type of supporting material for the textbook "Numerical Linear Algebra and Matrix Factorizations," published as Vol. 22 of Springer's Texts in Computational Science and Engineering series. Instead of omitting details or merely providing rough outlines, this book offers detailed proofs, and connects the solutions to the corresponding results in the textbook. For the algorithmic exercises the utmost level of detail is provided in the form of MATLAB implementations. Both the textbook and solutions are self-contained. This book and the textbook are of similar length, demonstrating that solutions should not be considered a minor aspect when learning at advanced levels.


Numerical Mathematics And Advanced Applications Enumath 2017

Author by : Florin Adrian Radu
Languange : en
Publisher by : Springer
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Total Read : 66
Total Download : 194
File Size : 47,8 Mb
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Description : This book collects many of the presented papers, as plenary presentations, mini-symposia invited presentations, or contributed talks, from the European Conference on Numerical Mathematics and Advanced Applications (ENUMATH) 2017. The conference was organized by the University of Bergen, Norway from September 25 to 29, 2017. Leading experts in the field presented the latest results and ideas in the designing, implementation, and analysis of numerical algorithms as well as their applications to relevant, societal problems. ENUMATH is a series of conferences held every two years to provide a forum for discussing basic aspects and new trends in numerical mathematics and scientific and industrial applications. These discussions are upheld at the highest level of international expertise. The first ENUMATH conference was held in Paris in 1995 with successive conferences being held at various locations across Europe, including Heidelberg (1997), Jyvaskyla (1999), lschia Porto (2001), Prague (2003), Santiago de Compostela (2005), Graz (2007), Uppsala (2009), Leicester (2011), Lausanne (2013), and Ankara (2015).


Quantification Of Uncertainty Improving Efficiency And Technology

Author by : Marta D'Elia
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 68
Total Download : 420
File Size : 48,5 Mb
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Description : This book explores four guiding themes – reduced order modelling, high dimensional problems, efficient algorithms, and applications – by reviewing recent algorithmic and mathematical advances and the development of new research directions for uncertainty quantification in the context of partial differential equations with random inputs. Highlighting the most promising approaches for (near-) future improvements in the way uncertainty quantification problems in the partial differential equation setting are solved, and gathering contributions by leading international experts, the book’s content will impact the scientific, engineering, financial, economic, environmental, social, and commercial sectors.


Domain Decomposition Methods In Science And Engineering Xxiv

Author by : Petter E. Bjørstad
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 27
Total Download : 572
File Size : 51,7 Mb
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Description : These are the proceedings of the 24th International Conference on Domain Decomposition Methods in Science and Engineering, which was held in Svalbard, Norway in February 2017. Domain decomposition methods are iterative methods for solving the often very large systems of equations that arise when engineering problems are discretized, frequently using finite elements or other modern techniques. These methods are specifically designed to make effective use of massively parallel, high-performance computing systems. The book presents both theoretical and computational advances in this domain, reflecting the state of art in 2017.


Scientific Computing

Author by : Bertil Gustafsson
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 74
Total Download : 725
File Size : 45,5 Mb
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Description : This book explores the most significant computational methods and the history of their development. It begins with the earliest mathematical / numerical achievements made by the Babylonians and the Greeks, followed by the period beginning in the 16th century. For several centuries the main scientific challenge concerned the mechanics of planetary dynamics, and the book describes the basic numerical methods of that time. In turn, at the end of the Second World War scientific computing took a giant step forward with the advent of electronic computers, which greatly accelerated the development of numerical methods. As a result, scientific computing became established as a third scientific method in addition to the two traditional branches: theory and experimentation. The book traces numerical methods’ journey back to their origins and to the people who invented them, while also briefly examining the development of electronic computers over the years. Featuring 163 references and more than 100 figures, many of them portraits or photos of key historical figures, the book provides a unique historical perspective on the general field of scientific computing – making it a valuable resource for all students and professionals interested in the history of numerical analysis and computing, and for a broader readership alike.


Recent Advances In Computational Engineering

Author by : Michael Schäfer
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 74
Total Download : 382
File Size : 48,6 Mb
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Description : This book comprises the proceedings of the 4th International Conference on Computational Engineering (ICCE 2017), held in Darmstadt, Germany on September 28-29, 2017. The conference is intended to provide an interdisciplinary meeting place for researchers and practitioners working on computational methods in all disciplines of engineering, applied mathematics and computer science. The aims of the conference are to discuss the state of the art in this challenging field, exchange experiences, develop promising perspectives for future research and initiate further cooperation. Computational Engineering is a modern and multidisciplinary science for computer-based modeling, simulation, analysis, and optimization of complex engineering applications and natural phenomena. The book contains an overview of selected approaches from numerics and optimization of Partial Differential Equations as well as uncertainty quantification techniques, typically in multiphysics environments. Where possible, application cases from engineering are integrated. The book will be of interest to researchers and practitioners of Computational Engineering, Applied Mathematics, Engineering Sciences and Computer Science.


Introduction To Numerical Methods For Variational Problems

Author by : Hans Petter Langtangen
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 78
Total Download : 797
File Size : 54,7 Mb
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Description : This textbook teaches finite element methods from a computational point of view. It focuses on how to develop flexible computer programs with Python, a programming language in which a combination of symbolic and numerical tools is used to achieve an explicit and practical derivation of finite element algorithms. The finite element library FEniCS is used throughout the book, but the content is provided in sufficient detail to ensure that students with less mathematical background or mixed programming-language experience will equally benefit. All program examples are available on the Internet.


Programming For Computations Python

Author by : Svein Linge
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 36
Total Download : 999
File Size : 42,8 Mb
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Description : This book is published open access under a CC BY 4.0 license. This book presents computer programming as a key method for solving mathematical problems. This second edition of the well-received book has been extensively revised: All code is now written in Python version 3.6 (no longer version 2.7). In addition, the two first chapters of the previous edition have been extended and split up into five new chapters, thus expanding the introduction to programming from 50 to 150 pages. Throughout the book, the explanations provided are now more detailed, previous examples have been modified, and new sections, examples and exercises have been added. Also, a number of small errors have been corrected. The book was inspired by the Springer book TCSE 6: A Primer on Scientific Programming with Python (by Langtangen), but the style employed is more accessible and concise, in keeping with the needs of engineering students. The book outlines the shortest possible path from no previous experience with programming to a set of skills that allows students to write simple programs for solving common mathematical problems with numerical methods in the context of engineering and science courses. The emphasis is on generic algorithms, clean program design, the use of functions, and automatic tests for verification.


Bem Based Finite Element Approaches On Polytopal Meshes

Author by : Steffen Weißer
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 71
Total Download : 124
File Size : 50,8 Mb
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Description : This book introduces readers to one of the first methods developed for the numerical treatment of boundary value problems on polygonal and polyhedral meshes, which it subsequently analyzes and applies in various scenarios. The BEM-based finite element approaches employs implicitly defined trial functions, which are treated locally by means of boundary integral equations. A detailed construction of high-order approximation spaces is discussed and applied to uniform, adaptive and anisotropic polytopal meshes. The main benefits of these general discretizations are the flexible handling they offer for meshes, and their natural incorporation of hanging nodes. This can especially be seen in adaptive finite element strategies and when anisotropic meshes are used. Moreover, this approach allows for problem-adapted approximation spaces as presented for convection-dominated diffusion equations. All theoretical results and considerations discussed in the book are verified and illustrated by several numerical examples and experiments. Given its scope, the book will be of interest to mathematicians in the field of boundary value problems, engineers with a (mathematical) background in finite element methods, and advanced graduate students.


Software For Exascale Computing Sppexa 2016 2019

Author by : Hans-Joachim Bungartz
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 65
Total Download : 742
File Size : 49,8 Mb
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Description : This open access book summarizes the research done and results obtained in the second funding phase of the Priority Program 1648 "Software for Exascale Computing" (SPPEXA) of the German Research Foundation (DFG) presented at the SPPEXA Symposium in Dresden during October 21-23, 2019. In that respect, it both represents a continuation of Vol. 113 in Springer’s series Lecture Notes in Computational Science and Engineering, the corresponding report of SPPEXA’s first funding phase, and provides an overview of SPPEXA’s contributions towards exascale computing in today's sumpercomputer technology. The individual chapters address one or more of the research directions (1) computational algorithms, (2) system software, (3) application software, (4) data management and exploration, (5) programming, and (6) software tools. The book has an interdisciplinary appeal: scholars from computational sub-fields in computer science, mathematics, physics, or engineering will find it of particular interest.


Sparse Grids And Applications Miami 2016

Author by : Jochen Garcke
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 57
Total Download : 765
File Size : 47,7 Mb
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Description : Sparse grids are a popular tool for the numerical treatment of high-dimensional problems. Where classical numerical discretization schemes fail in more than three or four dimensions, sparse grids, in their different flavors, are frequently the method of choice. This volume of LNCSE presents selected papers from the proceedings of the fourth workshop on sparse grids and applications, and demonstrates once again the importance of this numerical discretization scheme. The articles present recent advances in the numerical analysis of sparse grids in connection with a range of applications including computational chemistry, computational fluid dynamics, and big data analytics, to name but a few.


Numerical Methods For Flows

Author by : Harald van Brummelen
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 77
Total Download : 772
File Size : 50,9 Mb
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Description : This book includes selected contributions on applied mathematics, numerical analysis, numerical simulation and scientific computing related to fluid mechanics problems, presented at the FEF-“Finite Element for Flows” conference, held in Rome in spring 2017. Written by leading international experts and covering state-of-the-art topics in numerical simulation for flows, it provides fascinating insights into and perspectives on current and future methodological and numerical developments in computational science. As such, the book is a valuable resource for researchers, as well as Masters and Ph.D students.


Boundary And Interior Layers Computational And Asymptotic Methods Bail 2018

Author by : Gabriel R. Barrenechea
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 83
Total Download : 215
File Size : 44,6 Mb
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Description : This volume gathers papers presented at the international conference BAIL, which was held at the University of Strathclyde, Scotland from the 14th to the 22nd of June 2018. The conference gathered specialists in the asymptotic and numerical analysis of problems which exhibit layers and interfaces. Covering a wide range of topics and sharing a wealth of insights, the papers in this volume provide an overview of the latest research into the theory and numerical approximation of problems involving boundary and interior layers.


Spectral And High Order Methods For Partial Differential Equations Icosahom 2018

Author by : Spencer J. Sherwin
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 69
Total Download : 940
File Size : 40,6 Mb
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Description : This open access book features a selection of high-quality papers from the presentations at the International Conference on Spectral and High-Order Methods 2018, offering an overview of the depth and breadth of the activities within this important research area. The carefully reviewed papers provide a snapshot of the state of the art, while the extensive bibliography helps initiate new research directions.


An Introduction To Element Based Galerkin Methods On Tensor Product Bases

Author by : Francis X. Giraldo
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 12
Total Download : 578
File Size : 52,5 Mb
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Description : This book introduces the reader to solving partial differential equations (PDEs) numerically using element-based Galerkin methods. Although it draws on a solid theoretical foundation (e.g. the theory of interpolation, numerical integration, and function spaces), the book’s main focus is on how to build the method, what the resulting matrices look like, and how to write algorithms for coding Galerkin methods. In addition, the spotlight is on tensor-product bases, which means that only line elements (in one dimension), quadrilateral elements (in two dimensions), and cubes (in three dimensions) are considered. The types of Galerkin methods covered are: continuous Galerkin methods (i.e., finite/spectral elements), discontinuous Galerkin methods, and hybridized discontinuous Galerkin methods using both nodal and modal basis functions. In addition, examples are included (which can also serve as student projects) for solving hyperbolic and elliptic partial differential equations, including both scalar PDEs and systems of equations.


Dune The Distributed And Unified Numerics Environment

Author by : Oliver Sander
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 96
Total Download : 996
File Size : 50,7 Mb
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Description : The Distributed and Unified Numerics Environment (Dune) is a set of open-source C++ libraries for the implementation of finite element and finite volume methods. Over the last 15 years it has become one of the most commonly used libraries for the implementation of new, efficient simulation methods in science and engineering. Describing the main Dune libraries in detail, this book covers access to core features like grids, shape functions, and linear algebra, but also higher-level topics like function space bases and assemblers. It includes extensive information on programmer interfaces, together with a wealth of completed examples that illustrate how these interfaces are used in practice. After having read the book, readers will be prepared to write their own advanced finite element simulators, tapping the power of Dune to do so.


Numerical Geometry Grid Generation And Scientific Computing

Author by : Vladimir A. Garanzha
Languange : en
Publisher by : Springer Nature
Format Available : PDF, ePub, Mobi
Total Read : 67
Total Download : 323
File Size : 53,6 Mb
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Description : The focus of these conference proceedings is on research, development, and applications in the fields of numerical geometry, scientific computing and numerical simulation, particularly in mesh generation and related problems. In addition, this year’s special focus is on Delaunay triangulations and their applications, celebrating the 130th birthday of Boris Delaunay. In terms of content, the book strikes a balance between engineering algorithms and mathematical foundations. It presents an overview of recent advances in numerical geometry, grid generation and adaptation in terms of mathematical foundations, algorithm and software development and applications. The specific topics covered include: quasi-conformal and quasi-isometric mappings, hyperelastic deformations, multidimensional generalisations of the equidistribution principle, discrete differential geometry, spatial and metric encodings, Voronoi-Delaunay theory for tilings and partitions, duality in mathematical programming and numerical geometry, mesh-based optimisation and optimal control methods. Further aspects examined include iterative solvers for variational problems and algorithm and software development. The applications of the methods discussed are multidisciplinary and include problems from mathematics, physics, biology, chemistry, material science, and engineering.


Mechanobiology

Author by : Glen L. Niebur
Languange : en
Publisher by : Elsevier
Format Available : PDF, ePub, Mobi
Total Read : 63
Total Download : 896
File Size : 51,9 Mb
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Description : Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli Provides a review of diseases with known or purported mechanobiological underpinnings Includes the role of mechanobiology in tissue engineering and regenerative medicine Covers experimental methods to capture mechanobiological phenomena


Cellular And Biomolecular Mechanics And Mechanobiology

Author by : Amit Gefen
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 64
Total Download : 514
File Size : 50,5 Mb
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Description : This book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads.


Computer Models In Biomechanics

Author by : Gerhard Holzapfel
Languange : en
Publisher by : Springer Science & Business Media
Format Available : PDF, ePub, Mobi
Total Read : 59
Total Download : 424
File Size : 44,8 Mb
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Description : This book contains a collection of papers that were presented at the IUTAM Symposium on “Computer Models in Biomechanics: From Nano to Macro” held at Stanford University, California, USA, from August 29 to September 2, 2011. It contains state-of-the-art papers on: - Protein and Cell Mechanics: coarse-grained model for unfolded proteins, collagen-proteoglycan structural interactions in the cornea, simulations of cell behavior on substrates - Muscle Mechanics: modeling approaches for Ca2+–regulated smooth muscle contraction, smooth muscle modeling using continuum thermodynamical frameworks, cross-bridge model describing the mechanoenergetics of actomyosin interaction, multiscale skeletal muscle modeling - Cardiovascular Mechanics: multiscale modeling of arterial adaptations by incorporating molecular mechanisms, cardiovascular tissue damage, dissection properties of aortic aneurysms, intracranial aneurysms, electromechanics of the heart, hemodynamic alterations associated with arterial remodeling following aortic coarctation, patient-specific surgery planning for the Fontan procedure - Multiphasic Models: solutes in hydrated biological tissues, reformulation of mixture theory-based poroelasticity for interstitial tissue growth, tumor therapies of brain tissue, remodeling of microcirculation in liver lobes, reactions, mass transport and mechanics of tumor growth, water transport modeling in the brain, crack modeling of swelling porous media - Morphogenesis, Biological Tissues and Organs: mechanisms of brain morphogenesis, micromechanical modeling of anterior cruciate ligaments, mechanical characterization of the human liver, in vivo validation of predictive models for bone remodeling and mechanobiology, bridging scales in respiratory mechanics


Biomechanics In Oncology

Author by : Cheng Dong
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 34
Total Download : 513
File Size : 55,8 Mb
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Description : This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer


Multiscale Mechanobiology Of Bone Remodeling And Adaptation

Author by : Peter Pivonka
Languange : en
Publisher by : Springer
Format Available : PDF, ePub, Mobi
Total Read : 55
Total Download : 549
File Size : 50,6 Mb
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Description : The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.


Mechano Electric Correlations In The Human Physiological System

Author by : A. Bakiya
Languange : en
Publisher by : CRC Press
Format Available : PDF, ePub, Mobi
Total Read : 30
Total Download : 546
File Size : 49,8 Mb
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Description : The aim of Mechano-Electric Correlations in the Human Physiological System is to present the mechanical and electrical properties of human soft tissues and the mathematical models related to the evaluation of these properties in time, as well as their biomedical applications. This book also provides an overview of the bioelectric signals of soft tissues from various parts of the human body. In addition, this book presents the basic dielectric and viscoelastic characteristics of soft tissues, an introduction to the measurement and characteristics of bioelectric signals and their relationship with the mechanical activity, electromyography and the correlation of electromyograms with the muscle activity in normal and certain clinical conditions. The authors also present a case study on the effect of lymphatic filariasis on the mechanical and electrical activity of the muscle. Features: Explains the basics of electrical and mechanical properties of soft tissues in time and frequency domain along with the mathematical models of soft tissue mechanics Explores the correlation of electrical properties with the mechanical properties of biological soft tissues using computational techniques Provides a detailed introduction to electrophysiological signals along with the types, applications, properties, problems and associated mathematical models Explains the electromechanics of muscles using electromyography recordings from various muscles of the human physiological system Presents a case study on the effect of lymphatic filariasis on the mechanical and electrical activity of the muscle Mechano-Electric Correlations in the Human Physiological System is intended for biomedical engineers, researchers and medical scientists as well graduate and undergraduate students working on the mechanical properties of soft tissues.