Description : This book presents a highly readable yet realistic view of the possibilities for human missions to Mars. It provides for the first time a ‘level-headed’ assessment of plans for human exploration of Mars to counteract the tendency of space agencies to take an over-optimistic approach to such interplanetary missions. The author presents a detailed analysis of why, in his opinion, the current NASA approach will fail to send humans to Mars before 2080.
Description : Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian methodologies is lagging behind in the field of pharmaceutical development. Written specifically for pharmaceutical practitioners, Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies, describes a wide range of Bayesian applications to problems throughout pre-clinical, clinical, and Chemistry, Manufacturing, and Control (CMC) development. Authored by two seasoned statisticians in the pharmaceutical industry, the book provides detailed Bayesian solutions to a broad array of pharmaceutical problems. Features Provides a single source of information on Bayesian statistics for drug development Covers a wide spectrum of pre-clinical, clinical, and CMC topics Demonstrates proper Bayesian applications using real-life examples Includes easy-to-follow R code with Bayesian Markov Chain Monte Carlo performed in both JAGS and Stan Bayesian software platforms Offers sufficient background for each problem and detailed description of solutions suitable for practitioners with limited Bayesian knowledge Harry Yang, Ph.D., is Senior Director and Head of Statistical Sciences at AstraZeneca. He has 24 years of experience across all aspects of drug research and development and extensive global regulatory experiences. He has published 6 statistical books, 15 book chapters, and over 90 peer-reviewed papers on diverse scientific and statistical subjects, including 15 joint statistical works with Dr. Novick. He is a frequent invited speaker at national and international conferences. He also developed statistical courses and conducted training at the FDA and USP as well as Peking University. Steven Novick, Ph.D., is Director of Statistical Sciences at AstraZeneca. He has extensively contributed statistical methods to the biopharmaceutical literature. Novick is a skilled Bayesian computer programmer and is frequently invited to speak at conferences, having developed and taught courses in several areas, including drug-combination analysis and Bayesian methods in clinical areas. Novick served on IPAC-RS and has chaired several national statistical conferences.
Description : Human Capital in Gender and Development addresses timely feminist debates about the relationship between feminism, neoliberalism, and international development. The book engages with human capital theory, a labour economics theory associated with the Chicago School that now animates a wide range of political and economic governance. The book argues that human capital theory has been instrumental in constructing an economistic vision of gender equality as a tool for economic growth, and girls and women of the global South as the quintessential entrepreneurs of the post-global financial crisis era. The book’s critique of human capital theory and its role in Gender and Development gives insights into the kinds of development interventions that typify the ‘Gender Equality as Smart Economics’ agenda of the World Bank and other international development institutions. From the World Bank, to NGOs, and private businesses, discourses about the economic benefits of gender equality and women’s empowerment underpin a range of development interventions that aim to unlock the ‘untapped’ potential of the world’s women. Its implications are both conceptual and material, producing more interventionist forms of development governance, increased power by private sector actors in development, and de-politicization of gender equality issues. Human Capital in Gender and Development will be of particular interest to feminist scholars in Politics, International Relations, Development Studies, and Human Geography. It will also be a useful resource for teaching key debates about feminism, neoliberalism, and international development.
Description : New in paperback (originally published as HUMAN BY DESIGN): At the cutting edge of science and spirituality, New York Times best-selling author Gregg Braden explains that evolution is not the whole story of humanity--and offers a new understanding of our origins that can help us tap the extraordinary abilities we already have. What would it mean to discover we're designed to live extraordinary lives of self-healing, longevity, and deep intuition? Is it possible that the advanced awareness achieved by monks, nuns, and mystics--considered rare in the past--is actually meant to be a normal part of our daily lives? In this revelatory book, now available for the first time in paperback, five-time New York Times best-selling author and 2018 Templeton Award nominee Gregg Braden explains that we no longer need to ask these questions as "What if?" Recent discoveries ranging from human evolution and genetics to the new science of neuro-cardiology (the bridge between the brain and the heart) have overturned 150 years of thinking when it comes to the way we think of ourselves, our origin, and our capabilities. In this reader-friendly journey of discovery, Braden begins with the fact that we exist as we do, even more empowered, and more connected with ourselves and the world than scientists have believed in the past. It's this undisputable fact that leads to even deeper mysteries. "How do we awaken the extraordinary abilities that come from such an awesome connection?" "What role does our ancient and mysterious heritage play in our lives today?" Join Gregg as he crosses the traditional boundaries of science and spirituality to answer precisely these questions. In doing so he reveals a) specific tools, techniques, and practices to awaken our deep intuition on-demand, for self healing and longevity; and 2) concrete solutions to the social issues that are destroying our families and dividing us as people, including the bullying of young people, hate crimes, the growing epidemic of suicide, religious extremism, and more. When new discoveries prove that the existing human story is no longer based in fact, it's time to change the story. This simple truth is at the heart of the book you're about to read.
Description : International Law: Aspects of Regionalism evaluates regionalism in its various relationships and forms with respect to international law, as well as the importance and duties of international law in respect to the establishment and functioning of various forms of regional groups. A great deal of attention has been paid to regionalism from the global, political, ecocomic, security aspects, but a complex evaluation of the impact it has had on international law, and vice versa, is still lacking. The main purpose of this volume is to eliminate this gap and present the latest state of knowledge on the topic. This text will be of interest both to students at an advanced level, academics, and reflective practitioners. It addresses the topics with regard to international law and regionalism and will be of interest to academics dealing with legal aspects of current regionalism and for the specialized courses in the faculties of law, as well as anyone studying diplomacy and international studies, international relations, regional integration law, EU law, international law, and international relations.
Description : The church is going through a time of severe fracture over the issue of homosexuality. This book addresses the arguments from the gay Christian movement and revisionist theologians and exegetes on a single point: Can they withstand the evidence of the primary sources? In Unchanging Witness, Donald Fortson and Rollin Grams articulate the consistent orthodox view on homosexuality by presenting primary sources throughout Christian history and by interpreting the biblical texts in their cultural contexts. The first part of the book examines church history from the patristic period to the present day, and the second part engages biblical texts in light of Ancient Near Eastern, Jewish, Greek, and Roman primary sources. Throughout, the authors survey the conflicting and changing arguments of revisionist readings and contend that, in light of the overwhelming evidence of the relevant texts, the real issue is not one of interpretation but of biblical authority and Christian orthodoxy.
Description : The power of the image of the nude--the expressivity of the flesh--has inspired artists from the beginning. An understanding of human form is essential for artists to be able to express themselves with the figure. Anatomy makes the figure. Human Anatomy for Artists: The Elements of Form is the definitive analytical work on the anatomy of the human figure. No longer will working artists have to search high and low to find the information they need. In this, the most up-to-date and fully illustrated guide available, Eliot Goldfinger--sculptor, illustrator, scientific model-maker, and lecturer on anatomy--presents a single, all-inclusive reference to human form, capturing everything artists need in one convenient volume. Five years in the making, and featuring hundreds of photos and illustrations, this guide offers more views of each bone and muscle than any other book ever published: every structure that creates or influences surface form is individually illustrated in clear, carefully lit photographs and meticulous drawings. Informed by the detailed study of both live models and cadavers, it includes numerous unique presentations of surface structures--such as fat pads, veins, and genitalia--and of some muscles never before photographed. In addition, numerous cross sections, made with reference to CT scans, magnetic resonance imaging, and cut cadavers, trace the forms of all body regions and individual muscles. Information on each structure is placed on facing pages for ease of reference, and the attractive two-color format uses red ink to direct readers rapidly to important points and areas. Finally, an invaluable chapter on the artistic development of basic forms shows in a series of sculptures the evolution of the figure, head, and hands from basic axes and volumes to more complex organic shapes. This feature helps place the details of anatomy within the overall context of the figure. Certain to become the standard reference in the field, Human Anatomy for Artists will be indispensable to artists and art students, as well as art historians. It will also be a useful aid for physical and dance therapists, athletes and their trainers, bodybuilders, and anyone concerned with the external form of the human body. With the renewed interest in figurative art today, this will be an especially welcome volume.
Description : A state-of-the art review of conversational repair, with contributions from internationally recognized leaders in the field of conversation analysis.
Description : Sam Harris’s first book, The End of Faith, ignited a worldwide debate about the validity of religion. In the aftermath, Harris discovered that most people—from religious fundamentalists to nonbelieving scientists—agree on one point: science has nothing to say on the subject of human values. Indeed, our failure to address questions of meaning and morality through science has now become the most common justification for religious faith. It is also the primary reason why so many secularists and religious moderates feel obligated to "respect" the hardened superstitions of their more devout neighbors. In this explosive new book, Sam Harris tears down the wall between scientific facts and human values, arguing that most people are simply mistaken about the relationship between morality and the rest of human knowledge. Harris urges us to think about morality in terms of human and animal well-being, viewing the experiences of conscious creatures as peaks and valleys on a "moral landscape." Because there are definite facts to be known about where we fall on this landscape, Harris foresees a time when science will no longer limit itself to merely describing what people do in the name of "morality"; in principle, science should be able to tell us what we ought to do to live the best lives possible. Bringing a fresh perspective to age-old questions of right and wrong and good and evil, Harris demonstrates that we already know enough about the human brain and its relationship to events in the world to say that there are right and wrong answers to the most pressing questions of human life. Because such answers exist, moral relativism is simply false—and comes at increasing cost to humanity. And the intrusions of religion into the sphere of human values can be finally repelled: for just as there is no such thing as Christian physics or Muslim algebra, there can be no Christian or Muslim morality. Using his expertise in philosophy and neuroscience, along with his experience on the front lines of our "culture wars," Harris delivers a game-changing book about the future of science and about the real basis of human cooperation.
Description : Provides guidance for parents to help children master the techniques of cycling and includes information on safety skills and bike repair.