Post Genomic Cardiology

Post Genomic Cardiology
Author: José Marín-García
Publsiher: Academic Press
Total Pages: 944
Release: 2014-05-09
ISBN: 0124046428
Category: Science
Language: EN, FR, DE, ES & NL

Post Genomic Cardiology Book Excerpt:

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Aging and the Heart

Aging and the Heart
Author: José Marín-García
Publsiher: Springer Science & Business Media
Total Pages: 568
Release: 2007-12-07
ISBN: 0387740724
Category: Medical
Language: EN, FR, DE, ES & NL

Aging and the Heart Book Excerpt:

In this book, the genetic and molecular basis of cardiovascular aging is examined in detail and a comprehensive assessment given of the bioenergetics changes occurring in human and animal models of cardiac aging. Both current diagnostic and future therapeutic modalities are presented, giving this book a dual-pronged approach. Cardiac aging, like aging in general, is a complex process involving numerous cellular and molecular changes. This book sheds new light on the phenomenon.

Heart Failure

Heart Failure
Author: José Marín-García
Publsiher: Springer Science & Business Media
Total Pages: 470
Release: 2010-06-23
ISBN: 1607611473
Category: Medical
Language: EN, FR, DE, ES & NL

Heart Failure Book Excerpt:

Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies. Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF. Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. This book thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers. Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.

Signaling in the Heart

Signaling in the Heart
Author: José Marín-García
Publsiher: Springer Science & Business Media
Total Pages: 507
Release: 2011-06-21
ISBN: 1441994610
Category: Medical
Language: EN, FR, DE, ES & NL

Signaling in the Heart Book Excerpt:

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.

American Book Publishing Record

American Book Publishing Record
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2007
ISBN: 1928374650XXX
Category: American literature
Language: EN, FR, DE, ES & NL

American Book Publishing Record Book Excerpt:

Signaling in the Heart

Signaling in the Heart
Author: Anonim
Publsiher: Unknown
Total Pages: 528
Release: 2011-10-05
ISBN: 9781441994622
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Signaling in the Heart Book Excerpt:

Proteomic and Genomic Analysis of Cardiovascular Disease

Proteomic and Genomic Analysis of Cardiovascular Disease
Author: Jennifer E. Van Eyk,Michael J. Dunn
Publsiher: Wiley-Blackwell
Total Pages: 396
Release: 2003-04-10
ISBN: 1928374650XXX
Category: Science
Language: EN, FR, DE, ES & NL

Proteomic and Genomic Analysis of Cardiovascular Disease Book Excerpt:

This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the various strategies and technical aspects so as to assist the growing number of researchers intending to utilize these approaches. The result is an excellent way of educating and informing graduate students, post-doctoral fellows as well as researchers in academia and industry about the latest developments in this area.

Journal of molecular and cell cardiology

Journal of molecular and cell cardiology
Author: Anonim
Publsiher: Unknown
Total Pages: 904
Release: 1990
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Journal of molecular and cell cardiology Book Excerpt:

Identification of Novel Pathways for Cardiac Development and Disease Via Conditional Genetic Manipulation of Cardioblasts and Cardiomyocyte Lineages

Identification of Novel Pathways for Cardiac Development and Disease Via Conditional Genetic Manipulation of Cardioblasts and Cardiomyocyte Lineages
Author: Jason Tat-Kwong Lam
Publsiher: Unknown
Total Pages: 192
Release: 2005
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Identification of Novel Pathways for Cardiac Development and Disease Via Conditional Genetic Manipulation of Cardioblasts and Cardiomyocyte Lineages Book Excerpt:

Transactions of the Board of Trustees

Transactions of the Board of Trustees
Author: University of Illinois (System). Board of Trustees
Publsiher: Unknown
Total Pages: 135
Release: 2002
ISBN: 1928374650XXX
Category: Education, Higher
Language: EN, FR, DE, ES & NL

Transactions of the Board of Trustees Book Excerpt:

The Canadian Journal of Cardiology

The Canadian Journal of Cardiology
Author: Anonim
Publsiher: Unknown
Total Pages: 566
Release: 2008
ISBN: 1928374650XXX
Category: Cardiology
Language: EN, FR, DE, ES & NL

The Canadian Journal of Cardiology Book Excerpt:

Paediatric Cardiology

Paediatric Cardiology
Author: Robert Henry Anderson
Publsiher: Churchill Livingstone
Total Pages: 1327
Release: 2010
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Paediatric Cardiology Book Excerpt:

As patients live longer and need to be treated over the long term and the management of pediatric cardiology problems and congenital heart disease moves more into the mainstream. This book gives you coverage of potential cardiovascular anomalies, all potential diseases related to anomalies or developmental problems, and methods for management and treatment. New contributors from all over the world-including 70% new to this edition-present the latest challenges in the field and emphasize the adolescent and post-operative outcomes for management.

Endocrinology of the Heart in Health and Disease

Endocrinology of the Heart in Health and Disease
Author: Jonathan C. Schisler,Charles H Lang,Monte Willis
Publsiher: Academic Press
Total Pages: 378
Release: 2016-10-19
ISBN: 0128031123
Category: Medical
Language: EN, FR, DE, ES & NL

Endocrinology of the Heart in Health and Disease Book Excerpt:

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Malaria Parasites

Malaria Parasites
Author: Andrew P. Waters,C J Janse,Chris J. Janse
Publsiher: Caister Academic Press Limited
Total Pages: 554
Release: 2004
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Malaria Parasites Book Excerpt:

The completion of the Plasmodium falciparum genome sequence in late 2002 heralded a new era in malaria research. The search began in earnest for new drugs and vaccines to combat malaria, a disease which afflicts up to 500 million people worldwide and is responsible for the deaths of more than one million people each year. The new genomic data is aiding a greater understanding of the living parasite and its interaction with the insect vector and human host. In this book internationally renowned experts provide up-to-date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much more. The book is essential to all researchers working in this highly topical field and is recommended reading for scientists in other areas of biology and medicine.

Computational Cardiology

Computational Cardiology
Author: Frank B. Sachse
Publsiher: Springer Science & Business Media
Total Pages: 322
Release: 2004-04-15
ISBN: 3540219072
Category: Computers
Language: EN, FR, DE, ES & NL

Computational Cardiology Book Excerpt:

This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.

Science

Science
Author: John Michels (Journalist)
Publsiher: Unknown
Total Pages: 135
Release: 2001-08
ISBN: 1928374650XXX
Category: Science
Language: EN, FR, DE, ES & NL

Science Book Excerpt:

Philosophical Transactions of the Royal Society of London

Philosophical Transactions of the Royal Society of London
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2003
ISBN: 1928374650XXX
Category: Biology
Language: EN, FR, DE, ES & NL

Philosophical Transactions of the Royal Society of London Book Excerpt:

Philosophical Transactions

Philosophical Transactions
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2003
ISBN: 1928374650XXX
Category: Biology
Language: EN, FR, DE, ES & NL

Philosophical Transactions Book Excerpt:

Each issue of Transactions B is devoted to a specific area of the biological sciences, including clinical science. All papers are peer reviewed and edited to the highest standards. Published on the 29th of each month, Transactions B is essential reading for all biologists.

Proceedings of the Indian Science Congress

Proceedings of the Indian Science Congress
Author: Indian Science Congress Association
Publsiher: Unknown
Total Pages: 135
Release: 2003
ISBN: 1928374650XXX
Category: Science
Language: EN, FR, DE, ES & NL

Proceedings of the Indian Science Congress Book Excerpt:

Textbook of Interventional Cardiology

Textbook of Interventional Cardiology
Author: Eric J. Topol
Publsiher: Saunders
Total Pages: 1286
Release: 2008
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Textbook of Interventional Cardiology Book Excerpt:

The new edition brings you practical, evidence-based guidance on treating a full range of coronary lesions. It discusses techniques, devices, and adjunctive therapies and provides critical appraisals of emerging therapeutic approaches. Completely refocused and reorganized, the new edition is now in full-color and features a DVD of video clips demonstrating coronary intervention procedures, three new sections, and a plethora of new chapters.