Principles and Methods of Toxicology Fifth Edition

Principles and Methods of Toxicology  Fifth Edition
Author: A. Wallace Hayes
Publsiher: CRC Press
Total Pages: 2304
Release: 2007-09-25
ISBN: 9780849337789
Category: Medical
Language: EN, FR, DE, ES & NL

Principles and Methods of Toxicology Fifth Edition Book Excerpt:

Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.

Information Resources in Toxicology

Information Resources in Toxicology
Author: Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
Publsiher: Academic Press
Total Pages: 1054
Release: 2020-05-16
ISBN: 0128137258
Category: Medical
Language: EN, FR, DE, ES & NL

Information Resources in Toxicology Book Excerpt:

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources. Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles. Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals. Explores recent internet trends, web-based databases, and software tools in a section on the online environment. Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents. Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field.

The Toxicologist as Expert Witness

The Toxicologist as Expert Witness
Author: Arthur Furst
Publsiher: CRC Press
Total Pages: 134
Release: 2002-02-27
ISBN: 9781560325314
Category: Medical
Language: EN, FR, DE, ES & NL

The Toxicologist as Expert Witness Book Excerpt:

As the world becomes more complex, a greater percentage of the present litigation is based upon very technical subjects. More and more chemicals are being introduced into our daily lives, without ever having been tested for possible side-effects. Consequently, product liability is increasing, and more and more often the toxicologist is being called into court to explain to judges and juries the concepts of technology and risk assessment. The Toxicologist As Expert Witness: A Hint Book for Courtroom Procedure is written with the toxicologist in mind who may not have the experience to testify at a time when toxicolgists as expert witnesses are in great demand.

Information Resources in Toxicology

Information Resources in Toxicology
Author: P.J. Bert Hakkinen,Asish Mohapatra,Steven G. G. Gilbert
Publsiher: Academic Press
Total Pages: 1552
Release: 2009-08-19
ISBN: 9780080920030
Category: Science
Language: EN, FR, DE, ES & NL

Information Resources in Toxicology Book Excerpt:

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the “hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. • International in scope, with contributions from over 30 countries • Numerous key references and relevant Web links • Concise narratives about toxicologic sub-disciplines • Valuable appendices such as the IUPAC Glossary of Terms in Toxicology • Authored by experts in their respective sub-disciplines within toxicology

Toxicologic Pathology

Toxicologic Pathology
Author: Pritam S. Sahota,James A. Popp,Jerry F. Hardisty,Chirukandath Gopinath,Page Bouchard
Publsiher: CRC Press
Total Pages: 1224
Release: 2018-08-14
ISBN: 0429997469
Category: Medical
Language: EN, FR, DE, ES & NL

Toxicologic Pathology Book Excerpt:

Following the success of the first edition, this book is designed to provide practical and timely information for toxicologic pathologists working in pharmaceutical drug discovery and development. The majority of the book (Organ Systems) will provide detailed descriptions of histopathological lesions observed in drug development. In addition, it will provide information to assist the pathologist in making determinations of the origin of lesions as well as its relevance to human risk. Toxicologic Pathology: Nonclinical Safety Assessment, Second Edition includes 2 new concept chapters. The first of the new chapters address approaches for the evaluation of unique therapeutic modalities such as cell therapies, gene therapies, and gene expression knockdown therapies. While these still represent new developing therapeutic approaches, there has been significant experience with the therapeutic modalities in the last 5 years. The second new chapter addresses the nonclinical safety assessment of medical devices, a topic of increasing importance that was not addressed in a unique chapter in the first edition. The other concept chapters have been updated and cover important topics including the overview of drug development; principles of nonclinical safety assessment; an introduction to toxicologic pathology; techniques used in toxicologic pathology, clinical pathology, toxicokinetics, and drug development toxicogenomics; and spontaneous lesions. The 13 organ system chapters provide the specifics related to pathologic characteristics, differential diagnosis, and interpretation of toxic responses in each organ system. These chapters are specifically important for the bench pathologist but also for the toxicologist who interacts with pathologists and function as study toxicologists and project team representatives in the drug development arena.

Handbook of Toxicology of Chemical Warfare Agents

Handbook of Toxicology of Chemical Warfare Agents
Author: Ramesh C. Gupta
Publsiher: Academic Press
Total Pages: 1168
Release: 2009-04-02
ISBN: 9780080922737
Category: Medical
Language: EN, FR, DE, ES & NL

Handbook of Toxicology of Chemical Warfare Agents Book Excerpt:

This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book. This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with

Veterinary Toxicology

Veterinary Toxicology
Author: Ramesh C. Gupta
Publsiher: Academic Press
Total Pages: 1454
Release: 2012-04-23
ISBN: 0123859271
Category: Medical
Language: EN, FR, DE, ES & NL

Veterinary Toxicology Book Excerpt:

Veterinary Toxicology, 2nd Edition, is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This new edition brings together insights from qualified and well-experienced authorities across all areas of veterinary toxicology to provide an authoritative and in-depth look at all facets of veterinary toxicology, including target organ toxicity, melamine and cyanuric acid, toxicogenomics, chemical terrorism and nanoparticles. While most comparable texts are primarily directed toward the field of human toxicology, this is the one text needed to thoroughly prepare future veterinarians on the newest approaches for diagnosing poisoning cases in all animals from chemicals and plants of a diverse nature as a result of inadvertent, accidental, or malicious intents. It is thoroughly updated with new chapters and the latest coverage of topics not tackled in any previous books such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. There are also expanded discussions on international topics such as epidemiology of animal poisonings and regulatory guidelines and poisonous plants in Europe. Problem solving strategies are offered for treatment. This volume will be of interest to practitioners, professors and students of veterinary medicine and veterinary toxicology, poison control centers, marine biologists, environmentalists and animal scientists. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Managing Hazardous Materials Incidents Hospital emergency departments

Managing Hazardous Materials Incidents  Hospital emergency departments
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1992
ISBN: 1928374650XXX
Category: Emergency medical services
Language: EN, FR, DE, ES & NL

Managing Hazardous Materials Incidents Hospital emergency departments Book Excerpt:

Managing Hazardous Materials Incidents

Managing Hazardous Materials Incidents
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1992
ISBN: 1928374650XXX
Category: Emergency medical services
Language: EN, FR, DE, ES & NL

Managing Hazardous Materials Incidents Book Excerpt:

Fundamentals of Ecotoxicology Third Edition

Fundamentals of Ecotoxicology  Third Edition
Author: Michael C. Newman
Publsiher: CRC Press
Total Pages: 586
Release: 2010
ISBN: 1928374650XXX
Category: Nature
Language: EN, FR, DE, ES & NL

Fundamentals of Ecotoxicology Third Edition Book Excerpt:

Fully revised to reflect new developments, the new edition of this renowned text details key environmental contaminants, explores their gate and cycling in the biosphere, and discusses bioaccumulation and the effects of contaminants at increasing levels of ecological organization. It also covers regulatory aspects of the field and discusses key U.S., European, and Chinese legislation and policy. It provides new study questions, a detailed glossary, and new international case studies by leading world-known experts. This text ...

Information Resources in Toxicology

Information Resources in Toxicology
Author: Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
Publsiher: Academic Press
Total Pages: 808
Release: 2020-05-15
ISBN: 0128216123
Category: Medical
Language: EN, FR, DE, ES & NL

Information Resources in Toxicology Book Excerpt:

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Opens with an overview of the international toxicology scene, organizations and activities involved with both the science and regulatory framework, and a specific look at the European Union’s efforts. Offers an extensive collection of chapters covering over 40 countries and their toxicological infrastructure which includes listings of major books and journals, organizations, professional societies, universities, poison control centers, legislation, and online databases. Provides the Second Edition of the International Union of Pure and Applied Chemistry’s Glossary of Terms Used in Toxicology, a carefully constructed and peer reviewed collation of critical terms in the science. Concludes with a potpourri of quotes concerning toxicology and their use in the arts and popular culture. Paired with Volume One, which offers chapters on a host of toxicology sub-disciplines, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over120 chapters contributions by experts and leaders in the field.

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Eighth Edition
Author: Curtis Klaassen
Publsiher: McGraw Hill Professional
Total Pages: 1473
Release: 2013-04-25
ISBN: 0071769226
Category: Medical
Language: EN, FR, DE, ES & NL

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition Book Excerpt:

The most trusted all-in-one overview of the biomedical and environmental aspects of toxicology--NOW more complete, up-to-date, and in full color The world's leading and most authoritative textbook on poisons has more to offer students,toxicologists, and pharmacologists than ever before. Now in full color, and thoroughly revised, the eighth edition of Casarett & Doull's TOXICOLOGY: The Basic Science of Poisons not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere. Combined with the latest thinking by the field's foremost scholars plus solid coverage of general principles, modes of action, and chemical-specific toxicity, this landmark text continues to set the standard for toxicology references. NEW to the Eighth Edition FULL-COLOR design to allow for a clearer interpretation of the basic components of toxicology featured throughout the text EXPANDED tables, illustrations, and other visuals are updated with state-of-the-art standards that makes this edition even more current and relevant DVD with image bank features all tables and illustrations from the text in presentation-ready format NEW CHAPTERS include "Toxic Effects of Calories" and "Toxic Effects of Nanoparticles"

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Eighth Edition
Author: Louis J. Casarett,John Doull
Publsiher: McGraw Hill Professional
Total Pages: 1454
Release: 2013-06-19
ISBN: 0071769234
Category: Medical
Language: EN, FR, DE, ES & NL

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition Book Excerpt:

Casarett and Doull's has set the standard for toxicology reference texts for years, and is the market leading title to this day. It serves the general toxicology market, and is to the field what Goodman and Gilman is to pharmacology. The books are often purchased together, and form a knock-out punch along with our DiPiro textbook; combined, these three titles produce millions of dollars in revenue and more than 100,000 in unit sales. Casarett & Doull's is, in other words, one part of a triad that forms the best pharmacology/pharmacy/toxicology collection in all of medical publishing

Handbook of Chemical Health and Safety

Handbook of Chemical Health and Safety
Author: Robert J. Alaimo
Publsiher: Amer Chemical Society
Total Pages: 652
Release: 2001
ISBN: 1928374650XXX
Category: Science
Language: EN, FR, DE, ES & NL

Handbook of Chemical Health and Safety Book Excerpt:

Provides information on proper chemcial equipment handling including, purchasing, storage, use, and disposal.

Toxicology for Non toxicologists

Toxicology for Non toxicologists
Author: Mark E. Stelljes
Publsiher: Government Inst
Total Pages: 168
Release: 2000
ISBN: 1928374650XXX
Category: Science
Language: EN, FR, DE, ES & NL

Toxicology for Non toxicologists Book Excerpt:

Providing non-scientific readers with basic toxicological concepts, Toxicology for Non-Toxicologists explains how those concepts and their applications affect everyday life. Readers will find an introduction to the study of toxic chemicals on humans and the environment, close examinations of toxicology issues, and a discussion of the general approach to risk assessment.

Antiepileptic Drugs

Antiepileptic Drugs
Author: René H. Levy
Publsiher: Raven Press (ID)
Total Pages: 1025
Release: 1989
ISBN: 1928374650XXX
Category: Anticonvulsants
Language: EN, FR, DE, ES & NL

Antiepileptic Drugs Book Excerpt:

Revised to emphasize advances in chemotherapy of the epilepsies that have taken place since the 1982 edition. Presents the recent advances in knowledge concerning the antiepileptic drugs as well as a review of basic pharmacologic data from both animals and man. Topics covered include: general principles, phenytoin, phenobarbital, primidone, carbamazepine, valproate, ethosuximide, benzodiazepines, and other potential antiepileptic drugs. Annotation copyrighted by Book News, Inc., Portland, OR

Detection of New Adverse Drug Reactions

Detection of New Adverse Drug Reactions
Author: M. D. B. Stephens,J. C. C. Talbot,Philip Routledge
Publsiher: Nature Publishing Group
Total Pages: 546
Release: 1998
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Detection of New Adverse Drug Reactions Book Excerpt:

This book examines the drug information cycle within pharmaceutical companies and assesses existing methods of collection, storage and processing of adverse event data and outlines ways of improving the drug information cycle. It is the only reference covering the entire field of pharmacovigilance.

Hayes Handbook of Pesticide Toxicology

Hayes  Handbook of Pesticide Toxicology
Author: Wayland J. Hayes
Publsiher: Elsevier/AP
Total Pages: 1238
Release: 2010
ISBN: 1928374650XXX
Category: Electronic books
Language: EN, FR, DE, ES & NL

Hayes Handbook of Pesticide Toxicology Book Excerpt:

The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated third edition carries on the book's tradition of serving as the definitive reference on pesticide toxicology and recognizies the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife--Publisher description

Risk Assessment in Environmental Management

Risk Assessment in Environmental Management
Author: D. Kofi Asante-Duah
Publsiher: John Wiley & Sons
Total Pages: 515
Release: 1998-10-20
ISBN: 1928374650XXX
Category: Science
Language: EN, FR, DE, ES & NL

Risk Assessment in Environmental Management Book Excerpt:

Attempts to provide a concise, yet comprehensive overview of the many facets/aspects relating to chemical risk assessments. It presents some very important tools and methodologies that can be used to help resolve environmental contamination problems in a consistent, efficient and cost-effective way.

Polyclinic

Polyclinic
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1884
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Polyclinic Book Excerpt: