Principles of Bone Biology

Principles of Bone Biology
Author: John P. Bilezikian,Lawrence G. Raisz,T. John Martin
Publsiher: Academic Press
Total Pages: 1900
Release: 2008-09-29
ISBN: 9780080568751
Category: Medical
Language: EN, FR, DE, ES & NL

Principles of Bone Biology Book Excerpt:

Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition

Principles of Bone Biology 3rd Ed

Principles of Bone Biology  3rd Ed
Author: Lawrence G. Raisz
Publsiher: Unknown
Total Pages: 135
Release: 2008
ISBN: 9780123738844
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Principles of Bone Biology 3rd Ed Book Excerpt:

A Strategy for Research in Space Biology and Medicine in the New Century

A Strategy for Research in Space Biology and Medicine in the New Century
Author: National Research Council,Division on Engineering and Physical Sciences,Space Studies Board,Committee on Space Biology and Medicine
Publsiher: National Academies Press
Total Pages: 297
Release: 1998-10-16
ISBN: 0309060478
Category: Science
Language: EN, FR, DE, ES & NL

A Strategy for Research in Space Biology and Medicine in the New Century Book Excerpt:

Construction of the international space station, scheduled to start in late 1998, ushers in a new era for laboratory sciences in space. This is especially true for space life sciences, which include not only the use of low gravity as an experimental parameter to study fundamental biological processes but also the study of the serious physiological changes that occur in astronauts as they remain in space for increasingly longer missions. This book addresses both of these aspects and provides a comprehensive review of ground-based and space research in eleven disciplines, ranging from bone physiology to plant biology. It also offers detailed, prioritized recommendations for research during the next decade, which are expected to have a considerable impact on the direction of NASA's research program. The volume is also a valuable reference tool for space and life scientists.

A Strategy for Research in Space Biology and Medicine into the Next Century

A Strategy for Research in Space Biology and Medicine into the Next Century
Author: Committee on Space Biology and Medicine,Space Studies Board,Division on Engineering and Physical Sciences,National Research Council
Publsiher: National Academies Press
Total Pages: 257
Release: 1998-09-30
ISBN: 0309522064
Category: Science
Language: EN, FR, DE, ES & NL

A Strategy for Research in Space Biology and Medicine into the Next Century Book Excerpt:

Construction of the international space station, scheduled to start in late 1998, ushers in a new era for laboratory sciences in space. This is especially true for space life sciences, which include not only the use of low gravity as an experimental parameter to study fundamental biological processes but also the study of the serious physiological changes that occur in astronauts as they remain in space for increasingly longer missions. This book addresses both of these aspects and provides a comprehensive review of ground-based and space research in eleven disciplines, ranging from bone physiology to plant biology. It also offers detailed, prioritized recommendations for research during the next decade, which are expected to have a considerable impact on the direction of NASA's research program. The volume is also a valuable reference tool for space and life scientists.

Basic and Applied Bone Biology

Basic and Applied Bone Biology
Author: David B. Burr,Matthew R. Allen
Publsiher: Academic Press
Total Pages: 478
Release: 2019-02-20
ISBN: 0128132604
Category: Science
Language: EN, FR, DE, ES & NL

Basic and Applied Bone Biology Book Excerpt:

Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology. Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.). Presents an in-depth overview of skeletal biology, from molecular to organ level Offers refresher level content for clinicians or researchers outside their areas of expertise Includes updated and complete references Incorporates expanded study questions at the end of each chapter for further exploration Covers topics relevant to a modern course in skeletal biology

Genetics of Bone Biology and Skeletal Disease

Genetics of Bone Biology and Skeletal Disease
Author: Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi
Publsiher: Academic Press
Total Pages: 878
Release: 2017-10-31
ISBN: 0128041986
Category: Medical
Language: EN, FR, DE, ES & NL

Genetics of Bone Biology and Skeletal Disease Book Excerpt:

Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder

Biodegradable Systems in Tissue Engineering and Regenerative Medicine

Biodegradable Systems in Tissue Engineering and Regenerative Medicine
Author: Rui L. Reis,Julio San Román
Publsiher: CRC Press
Total Pages: 592
Release: 2004-11-29
ISBN: 1135494428
Category: Medical
Language: EN, FR, DE, ES & NL

Biodegradable Systems in Tissue Engineering and Regenerative Medicine Book Excerpt:

Conventional materials technology has yielded clear improvements in regenerative medicine. Ideally, however, a replacement material should mimic the living tissue mechanically, chemically, biologically and functionally. The use of tissue-engineered products based on novel biodegradable polymeric systems will lead to dramatic improvements in health

Bisphosphonates in Bone Disease

Bisphosphonates in Bone Disease
Author: Herbert Fleisch
Publsiher: Elsevier
Total Pages: 212
Release: 2000-06-12
ISBN: 0080573908
Category: Medical
Language: EN, FR, DE, ES & NL

Bisphosphonates in Bone Disease Book Excerpt:

This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, Fourth Edition, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. The revised fourth edition contains approximately 50% new material Includes information on all the latest drugs

Origins of Cattle Traction and the Making of Early Civilisations in North China

Origins of Cattle Traction and the Making of Early Civilisations in North China
Author: Minghao Lin
Publsiher: Springer Nature
Total Pages: 231
Release: 2022-09-13
ISBN: 3031155351
Category: Social Science
Language: EN, FR, DE, ES & NL

Origins of Cattle Traction and the Making of Early Civilisations in North China Book Excerpt:

This book is the first to apply systematic palaeopathological, archaeological and historical investigations (using bones as a focus as well as other supporting lines of information) to Chinese osteological materials in order to answer the question about the origins of cattle labour. Structurally, this monograph flows from an introduction and review of previous scholarship and questions, through employed theory and developed methods, to analyses of archaeological materials, and finally finishes by overall discussion and closing remarks. Topics covered in this monograph include the significance of the study of cattle traction in North China, understanding and research into cattle traction within history, art and archaeology, and identifying traction in cattle bones. The author also uses the Pathological Index-refined (PIr) and morphometrics to test the reliability of both methods in identifying traction in cattle bones. The author applies both methods to archaeological sites in the Yellow River region. This book is of interest to researchers studying the Late Bronze Age and zooarchaeology.

Pediatric Bone

Pediatric Bone
Author: Francis H. Glorieux,John M Pettifor,Harald Juppner
Publsiher: Academic Press
Total Pages: 868
Release: 2011-08-22
ISBN: 0123820413
Category: Medical
Language: EN, FR, DE, ES & NL

Pediatric Bone Book Excerpt:

The second edition of this classic reference deals exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone that are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in children. Deals exclusively with bone development and diseases of children and each chapter is written by an expert in the field Fully referenced providing an appendix of usually difficult to find information on the investigation of pediatric bone disease and reference values Covers both the physiology of bone and mineral homeostasis in children and diseases in one book

Dorfman and Czerniak s Bone Tumors E Book

Dorfman and Czerniak   s Bone Tumors E Book
Author: Bogdan Czerniak
Publsiher: Elsevier Health Sciences
Total Pages: 1520
Release: 2015-08-19
ISBN: 0323091598
Category: Medical
Language: EN, FR, DE, ES & NL

Dorfman and Czerniak s Bone Tumors E Book Book Excerpt:

The second edition of Dorfman and Czerniak's Bone Tumors brings together the latest data available on bone tumor pathology, making it the most comprehensive and encyclopedic reference on the epidemiology, clinical, pathologic, and molecular aspects of bone tumors. Now offered in full color and featuring updated imaging throughout, this one-of-a-kind resource provides a highly visual review of every disorder — from the common to the rare. Features comprehensive coverage of bone tumor pathology based on pathologic and clinical data on 11,500 benign and malignant bone tumors from patients treated at the MD Anderson Cancer Center. High-quality full-color images located throughout the text. Completely up-to-date molecular and genetic information is based on the most current genomic databases. Four brand-new chapters cover Radiographic Imaging of Bone Tumors; Hematopoetic Tumors; Neural Tumors; and Metastic Tumors of Bone. Includes information on molecular and genetic aspects of bone tumors from the UCSC Genome Browser, the Catologue of Somatic Mutations in Cancer, and the GeneCards Database of human genes. Features comprehensive data from nearly 30,000 benign and malignant primary bone tumors and tumor-like lesions from different sources, including over 8,400 malignant bone tumors from the National Cancer Institute’s Surveillance, Epidemiology and End Result project. Provides an enhanced visual understanding with updated radiographic imaging and new full-color, high-quality photomicrographs. Updated Molecular and Epidemiologic diagrams added to all new chapters.

Prevention and Management of Osteoporosis

Prevention and Management of Osteoporosis
Author: WHO Scientific Group on Prevention and Management of Osteoporosis,World Health Organization
Publsiher: World Health Organization
Total Pages: 206
Release: 2003-12-31
ISBN: 9241209216
Category: Medical
Language: EN, FR, DE, ES & NL

Prevention and Management of Osteoporosis Book Excerpt:

Bone is hard tissue that is in a constant state of flux being built up by bone-forming cells called osteoblasts while also being broken down or resorbed by cells known as osteoclasts. During childhood and adolescence bone formation is dominant; bone length and girth increase with age ending at early adulthood when peak bone mass is attained. Males generally exhibit a longer growth period resulting in bones of greater size and overall strength. In males after the age of 20 bone resorbtion becomes predominant and bone mineral content declines about 4% per decade. Females tend to maintain peak mineral content until menopause at which time it declines about 15% per decade. Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue leading to bone fragility and an increased susceptibility to fractures especially of the hip spine and wrist. Osteoporosis occurs primarily as a result of normal ageing but can arise as a result of impaired development of peak bone mass (e.g. due to delayed puberty or undernutrition) or excessive bone loss during adulthood (e.g. due to estrogen deficiency in women undernutrition or corticosteriod use). Osteoporosis-induced fractures cause a great burden to society. Hip fractures are the most serious as they nearly always result in hospitalization are fatal about 20% of the time and produce permanent disability about half the time. Fracture rates increase rapidly with age and the lifetime risk of fracture in 50 year-old women is about 40% similar to that for coronary heart disease. In 1990 there were 1.7 million hip fractures alone worldwide; with changes in population demographics this figure is expected to rise to 6 million by 2050. To help describe the nature and consequences of osteoporosis as well as strategies for its prevention and management a WHO Scientific Group meeting of international experts was held in Geneva which resulted in this technical report. This monograph describes in detail normal bone development and the causes and risk factors for developing osteoporosis. The burden of osteoporosis is characterized in terms of mortality morbidity and economic costs. Methods for its prevention and treatment are discussed in detail for both pharmacological and non-pharmacological approaches. For each approach the strength of the scientific evidence is listed. The report also provides cost-analysis information for potential interventions and discusses important aspects of developing national policies to deal with osteoporosis. Recommendations are made to the general population care providers health administrators and researchers. Lastly national organizations and support groups are listed by country.

Endocrinology Adult and Pediatric The Parathyroid Gland and Bone Metabolism

Endocrinology Adult and Pediatric  The Parathyroid Gland and Bone Metabolism
Author: John T. Potts Jr.,J. Larry Jameson,Leslie De Groot
Publsiher: Elsevier Health Sciences
Total Pages: 301
Release: 2013-06-20
ISBN: 0323090982
Category: Medical
Language: EN, FR, DE, ES & NL

Endocrinology Adult and Pediatric The Parathyroid Gland and Bone Metabolism Book Excerpt:

Effectively manage parathyroid and bone metabolism disorders with The Parathyroid Gland and Bone Metabolism! Brought to you by the same leading endocrinologists responsible for the highly acclaimed two-volume textbook, Endocrinology: Adult and Pediatric, this eBook presents a compilation of chapters covering all endocrinology material related to parathyroid and bone metabolism. Never before available as a stand-alone offering, this content will enable you to give your patients the benefit of today’s best know-how on parathyroid and bone metabolism from the leading resource in endocrinology. Stay abreast of the newest knowledge and advances on parathyroid and bone metabolism, including... pediatric parathyroid disorders and bone metabolism disorders major diseases common to the aging population, such as osteoporosis advances in the genetics of disorders involving calciotropic hormones newer diagnostic approaches and therapies for bone diseases, from osteoporosis to Paget’s disease and much more. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and De Groot, the go-to clinical medical reference for endocrinologists worldwide. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.

Intercellular Signaling in Development and Disease

Intercellular Signaling in Development and Disease
Author: Edward A. Dennis,Ralph A. Bradshaw
Publsiher: Academic Press
Total Pages: 550
Release: 2011-04-08
ISBN: 0123822157
Category: Science
Language: EN, FR, DE, ES & NL

Intercellular Signaling in Development and Disease Book Excerpt:

"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.

Bone Formation

Bone Formation
Author: Felix Bronner
Publsiher: Springer Science & Business Media
Total Pages: 184
Release: 2004
ISBN: 9781852337179
Category: Medical
Language: EN, FR, DE, ES & NL

Bone Formation Book Excerpt:

Bone research in recent years has generated much new knowledge, in large measure because of the broad public health implications of osteoporosis and related bone disorders. Bone Formation, the first in a series entitled Topics in Bone Biology, evaluates this new information and formulates novel insights and hypotheses within the broad framework of current knowledge. An easy-to handle and to read work, with concise reviews that are extensively referenced, the chapters in this book are written by internationally known authorities. Particular emphasis is on osteoporosis and related disorders of diminished bone formation. Among the general topics treated is a chapter on biomechanical aspects of bone formation, not often considered in relation to diseases of bone formation. The book constitutes essential reading for those entering the field of bone biology and those who wish to become familiar with up-to-date information in a particular area of bone research.

Radiology of Osteoporosis

Radiology of Osteoporosis
Author: Stephan Grampp
Publsiher: Springer Science & Business Media
Total Pages: 204
Release: 2013-06-29
ISBN: 3662052350
Category: Medical
Language: EN, FR, DE, ES & NL

Radiology of Osteoporosis Book Excerpt:

Due to the aging population in the Western world, osteoporosis has become a major problem which is of interest to several medical disciplines: not only radiologists but also gynecologists, endocrinologists, rheumatologists, and orthopedic surgeons are involved in the management of this widespread condition. Functional imaging is becoming rapidly an important area of diagnostic radiology. Imaging of osteoporosis is another application of this recent addition to the armory of radiology. It is important that radiologists should be fully aware of the range of diagnostic modalities-conventional radiologic methods, dual X-ray absorptiometry, quantitative computed tomography, quantitative ultrasound, magnetic resonance imaging, etc. -that are now available for the diagnosis and the follow-up of osteoporosis, and know how to apply these sophisticated methods in daily clinical practice. Dr. S. Grampp is a radiologist with a longstanding interest in osteoporosis, and his previous publications on this condition are internationally known. He has been very successful in engaging several outstandingly qualified experts to contribute to the indi vidual chapters of this superb book, which provides a omprehensive c overview of our current knowledge of osteoporosis. I am confident that this volume will meet with great interest from radiologists and all other clinicians involved in the care of patients with osteoporosis and will encounter the same success as many previous volumes in this series.

The Osteoporosis Primer

The Osteoporosis Primer
Author: Janet E. Henderson,David Goltzman
Publsiher: Cambridge University Press
Total Pages: 390
Release: 2000-08-24
ISBN: 9780521644464
Category: Medical
Language: EN, FR, DE, ES & NL

The Osteoporosis Primer Book Excerpt:

The Osteoporosis Primer provides an excellent introduction that relates the clinical presentation of osteoporosis to its molecular biochemical basis, and reviews therapeutic options.

Case Studies in Forensic Anthropology

Case Studies in Forensic Anthropology
Author: Heather M. Garvin,Natalie R. Langley
Publsiher: CRC Press
Total Pages: 312
Release: 2019-11-04
ISBN: 042979259X
Category: Science
Language: EN, FR, DE, ES & NL

Case Studies in Forensic Anthropology Book Excerpt:

Through a set of unique case studies written by an international group of practicing forensic anthropologists, Case Studies in Forensic Anthropology: Bonified Skeletons prepares students and professionals for the diverse range of cases and challenges they will encounter in the field. Every forensic anthropology case is unique. Practitioners routinely face new challenges and unexpected outcomes. Courses and introductory texts generally address standard or ideal cases. In practice, however, forensic anthropologists must improvise frequently during forensic archaeological recoveries and laboratory analyses based on case circumstances. Most forensic anthropologists have encountered unconventional cases with surprising results. While these cases act as continuing education for practitioners—better preparing them for future encounters— such learning opportunities may be limited by the extent of personal experiences. This text exposes practitioners and students to a diverse array of case examples they may not otherwise encounter, sharing experiential knowledge and contributing to the advancement the field. Case Studies in Forensic Anthropology aims to both prepare aspiring forensic anthropologists and inform current practitioners. The cases are interesting and unique, detailing how specific challenges contribute to the body of forensic anthropological knowledge and practice. Key Features Full-color photographs illustrate the scenes and skeletal features "Lessons Learned" sections for each case study emphasize take-away points Thought-provoking "Discussion Questions" encourage readers to think critically and facilitate group discussions Actual case experiences by diverse array of forensic anthropologists who discuss innovative methods and unique challenges

Human Osteology

Human Osteology
Author: Tim D. White,Michael T. Black,Pieter A. Folkens
Publsiher: Academic Press
Total Pages: 688
Release: 2011-01-21
ISBN: 9780080920856
Category: Medical
Language: EN, FR, DE, ES & NL

Human Osteology Book Excerpt:

A classic in its field, Human Osteology has been used by students and professionals through nearly two decades. Now revised and updated for a third edition, the book continues to build on its foundation of detailed photographs and practical real-world application of science. New information, expanded coverage of existing chapters, and additional supportive photographs keep this book current and valuable for both classroom and field work. Osteologists, archaeologists, anatomists, forensic scientists and paleontologists will all find practical information on accurately identifying, recovering, and analyzing and reporting on human skeletal remains and on making correct deductions from those remains. From the world renowned and bestselling team of osteologist Tim D. White, Michael T. Black and photographer Pieter A. Folkens Includes hundreds of exceptional photographs in exquisite detail showing the maximum amount of anatomical information Features updated and expanded coverage including forensic damage to bone and updated case study examples Presents life sized images of skeletal parts for ease of study and reference

Characterization of Polymeric Biomaterials

Characterization of Polymeric Biomaterials
Author: Maria Cristina Tanzi,Silvia Farè
Publsiher: Woodhead Publishing
Total Pages: 500
Release: 2017-06-20
ISBN: 0081007434
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Characterization of Polymeric Biomaterials Book Excerpt:

Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants. With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications. Presents a self-contained reference on the characterization of polymeric biomaterials Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis Includes useful case studies that demonstrate the characterization of biomaterial implants