Description : Basic Neurochemistry: Molecular, Cellular and Medical Aspects, a comprehensive text on neurochemistry, is now updated and revised in its Seventh Edition. This well-established text has been recognized worldwide as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for graduate and postgraduate students and instructors in the neurosciences. It is an excellent source of information on basic biochemical processes in brain function and disease for qualifying examinations and continuing medical education. Completely updated with 60% new authors and material, and entirely new chapters Over 400 fully revised figures in splendid color
Description : Schwann cells are a diverse group of cells formed from neural crest cells. They are essential components of the peripheral nerves of both vertebrate and invertebrate nervous systems. The diversity of Schwann cell subsets and function is seen in those Schwann cells that form myelin - that uniquely specialised part of the plasma membrane that spirals around axonal lengths to myelinate the peripheral nerves. The Biology of Schwann Cells concentrates on the cells of mammals and in particular humans. It covers the distinction between compact and non-compact myelin in depth, along with the perisynaptic cells which form the partnership between nerve terminals and muscle fibre. Developmental aspects are discussed alongside differentiation, and the genetics of the cells in health and disease. With chapters from world-renowned experts, this book is aimed at postgraduates and researchers in neuroscience and neurology and anyone involved in the study of peripheral nerves.
Description : This book presents recent topics on the development, differentiation, and myelination of Schwann cells, as well as pathological mechanisms and therapeutic approaches for peripheral neuropathies, such as Charcot–Marie–Tooth diseases, amyloid polyneuropathy, immune-mediated neuropathy and diabetic neuropathy. The rapid progress of molecular biological techniques in the last decades, especially for RNA techniques and gene modification technologies have allowed us to investigate the pathobiology of Schwann cells in vivo and in vitro. Studies combining recent stem cell biology with recent biotechnology, which is now closely linked to physicochemical fields, further explain how Schwann cell lineages develop a process that has long been thought to be very complicated in vivo. The findings contribute to the elucidation of fundamental mechanisms during development and under pathological conditions. We now know that these are closely tied to each other. This book also introduces unique coculture systems to reproduce the neuron–Schwann cell interplay during development, degeneration, and regeneration. Up-to-date research topics with high-quality immunofluorescence and electron micrographs introduced by young and energetic contributors are sure to arouse the readers' interest in Schwann cell biology. Discussion from the viewpoint of basic and clinical neuroscience makes the book educational for researchers, medical students and young clinicians.
Description : Schwann Cells—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Schwann Cells in a compact format. The editors have built Schwann Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Schwann Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Schwann Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Description : Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, this book provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors. This book is the first of its kind, encyclopedic and wide-ranging.
Description : Transplantation of Neural Tissues into the Spinal Cord presents both recent and early results from various experiments where grafts of neuronal, glial and other tissues, as well as artificial materials, were placed into the spinal cord. This book is evaluates the contribution and effect of these studies to our understanding of basic neurobiological questions. This second edition of the book provides answers to many questions which could not be answered in the first edition, and accordingly all the chapters have been extensively rewritten and edited. The findings summarized in this edition show that grafted tissue can survive and thrive in a host mammal, occasionally replace some lost function and re-establish a semblance of sophisticated and complex circuitries. These new insights are among the most exciting in neurobiology, for they challenge the view that nothing can grow or regenerate in the central nervous system and give new hope that it may be possible to treat some of the incurable diseases of the CNS.
Description : The fourth edition of this highly successful text has been extensively revised and restructured to take account of the many recent advances in the field. The classic observations of recent years can now be interpreted with the powerful new techniques of molecular biology. Consequently, there is much new material throughout the book, including many new illustrations and extensive references to recent work. The text's essential philosophy remains the same, however: it clearly explains fundamental concepts, and examines key experiments in detail. This thorough and clearly written textbook will be valuable for students of physiology, neuroscience, cell biology and biophysics.
Description : Glial cells are commonly viewed as subordinate players to the functional requirements of neighbouring neurons – in normal as well as pathological conditions. These neuron-glial interactions are crucial for the development, maintenance, plasticity and repair of the nervous system. They are also dependent upon and/or influenced by interactions between glial cells themselves. This book provides a unique focus on structural, molecular and physiological aspects of glial-glial interactions in the nervous system and their significance for neuronal function, integrity, regeneration and repair. It emphasises the possibilities for modifying these interactions and the consequent opportunities for developing new therapies, which counteract neuronal injury and/or promote recovery from neurological disorders such as paraplegia and stroke.
Description : This monograph contains research articles from the leading laboratories around the world on gap junctions, the intercellular channels that allow communication between neighbouring cells. It describes the latest results in gap junctions research, the structural and functional characterization of cell-cell channels, the assembly and degradation of gap junctions, the expression and function of gap junctions in different tissues, knockout studies of gap junction genes, the regulation of connexin gene expression, and the functions of gap junctions in development and cancer. Any laboratory interested in intercellular communications and gap junction research will find this monograph an indispensable source of information and reference.