Sex and Gender Differences in Alzheimer s Disease

Sex and Gender Differences in Alzheimer s Disease
Author: Maria Teresa Ferretti,Annemarie Schumacher Dimech,Antonella Santuccione Chadha
Publsiher: Academic Press
Total Pages: 512
Release: 2021-07-23
ISBN: 012819345X
Category: Medical
Language: EN, FR, DE, ES & NL

Sex and Gender Differences in Alzheimer s Disease Book Excerpt:

Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease. This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Provides a comprehensive and critical review of sex differences in Alzheimer’s disease Features discussion of sex and gender differences in disease biology, treatment, and socioeconomic factors, including impact on caregivers Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists, policymakers, health scientists, and clinical trial experts, for a 360-degree view on the topic and its possible implications Edited by the Women’s Brain Project, the leading NGO in the field of sex and gender differences in brain and mental health as the gateway to precision medicine

Sex Differences in Neurology and Psychiatry

Sex Differences in Neurology and Psychiatry
Author: Anonim
Publsiher: Elsevier
Total Pages: 476
Release: 2020-09-30
ISBN: 0444641246
Category: Medical
Language: EN, FR, DE, ES & NL

Sex Differences in Neurology and Psychiatry Book Excerpt:

Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Sex and Gender Bias in Technology and Artificial Intelligence

Sex and Gender Bias in Technology and Artificial Intelligence
Author: Davide Cirillo,Silvina Catuara Solarz,Emre Guney
Publsiher: Academic Press
Total Pages: 278
Release: 2022-05-21
ISBN: 0128213930
Category: Medical
Language: EN, FR, DE, ES & NL

Sex and Gender Bias in Technology and Artificial Intelligence Book Excerpt:

Sex and Gender Bias in Technology and Artificial Intelligence: Biomedicine and Healthcare Applications details the integration of sex and gender as critical factors in innovative technologies (artificial intelligence, digital medicine, natural language processing, robotics) for biomedicine and healthcare applications. By systematically reviewing existing scientific literature, a multidisciplinary group of international experts analyze diverse aspects of the complex relationship between sex and gender, health and technology, providing a perspective overview of the pressing need of an ethically-informed science. The reader is guided through the latest implementations and insights in technological areas of accelerated growth, putting forward the neglected and overlooked aspects of sex and gender in biomedical research and healthcare solutions that leverage artificial intelligence, biosensors, and personalized medicine approaches to predict and prevent disease outcomes. The reader comes away with a critical understanding of this fundamental issue for the sake of better future technologies and more effective clinical approaches. First comprehensive title addressing the topic of sex and gender biases and artificial intelligence applications to biomedical research and healthcare Co-published by the Women’s Brain Project, a leading non-profit organization in this area Guides the reader through important topics like the Generation of Clinical Data, Clinical Trials, Big Data Analytics, Digital Biomarkers, Natural Language Processing

How Sex and Gender Impact Clinical Practice

How Sex and Gender Impact Clinical Practice
Author: Marjorie Jenkins,Connie B. Newman
Publsiher: Academic Press
Total Pages: 360
Release: 2020-12-02
ISBN: 0128167505
Category: Science
Language: EN, FR, DE, ES & NL

How Sex and Gender Impact Clinical Practice Book Excerpt:

How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges

Down Syndrome Neurodegeneration and Dementia

Down Syndrome  Neurodegeneration and Dementia
Author: Sylvia Eva Perez,Tao Ma,Elliott Jay Mufson,Stephen D. Ginsberg,Aurélie Ledreux
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-01-27
ISBN: 2889742091
Category: Science
Language: EN, FR, DE, ES & NL

Down Syndrome Neurodegeneration and Dementia Book Excerpt:

Evidence for Assessing Drug Safety and Drug Use in Older People

Evidence for Assessing Drug Safety and Drug Use in Older People
Author: Vera Maria Vieira Paniz,Fabiane Raquel Motter,Luciane Cruz Lopes,Marcio Galvão Oliveira,Ria Benko,Brian Godman
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-06-28
ISBN: 2889764370
Category: Science
Language: EN, FR, DE, ES & NL

Evidence for Assessing Drug Safety and Drug Use in Older People Book Excerpt:

Identification of Multiple Targets in the Fight against Alzheimer s Disease

Identification of Multiple Targets in the Fight against Alzheimer   s Disease
Author: Patrizia Giannoni,Silvia Fossati,Sylvie Claeysen,Elena Marcello
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-07-31
ISBN: 2889639096
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Identification of Multiple Targets in the Fight against Alzheimer s Disease Book Excerpt:

Social Public Policy of Alzheimer s Disease in the United States

Social   Public Policy of Alzheimer s Disease in the United States
Author: Robert H. Blank
Publsiher: Springer
Total Pages: 171
Release: 2018-06-13
ISBN: 9811306567
Category: Political Science
Language: EN, FR, DE, ES & NL

Social Public Policy of Alzheimer s Disease in the United States Book Excerpt:

This book focuses on the public policy and political dimensions of Alzheimer’s Disease and other dementias (AD/D) in the United States, with coverage of the global dimensions and relevant examples from other countries. Starting off with a discussion on the characteristics of AD/D and competing theories of their causes, their human and financial costs, and the increasing burden they place on all societies as populations age, the book examines in detail the range of policy issues they raise. These include funding policies, payment policy and regulatory functions, long-term services and support (LTCS), public health and prevention policies. The book analyses the big business surrounding AD/D and shows that the strong public fear of developing dementia heightens the likelihood of exploitation of vulnerable people looking for a technological fix. It examines both informal and formal caregivers and the heavy burden placed on families, primarily women, and recent policy attempts to strengthen LTCS. It also examines the latest evidence of potential risk-reduction and prevention strategies and the difficult issues surrounding advance directives, assisted suicide, and definitions of death that increasingly face policy makers. It concludes by analyzing the policy implications on possible technological scenarios.

The Male and Female Brain Molecular Mechanisms of Sex Differences

The Male and Female Brain  Molecular Mechanisms of Sex Differences
Author: Laura Musazzi,Jordan Marrocco
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-12-30
ISBN: 2889718875
Category: Science
Language: EN, FR, DE, ES & NL

The Male and Female Brain Molecular Mechanisms of Sex Differences Book Excerpt:

Women s Mental Health An Issue of Medical Clinics of North America An Issue of Medical Clinics of North America E Book

Women s Mental Health  An Issue of Medical Clinics of North America  An Issue of Medical Clinics of North America  E Book
Author: Susan G. Kornstein,Anita H. Clayton
Publsiher: Elsevier Health Sciences
Total Pages: 240
Release: 2019-05-11
ISBN: 0323713467
Category: Medical
Language: EN, FR, DE, ES & NL

Women s Mental Health An Issue of Medical Clinics of North America An Issue of Medical Clinics of North America E Book Book Excerpt:

This issue of Medical Clinics, edited by Drs. Susan G. Kornstein and Anita H. Clayton, will cover a wide arrange of topics in the field of Women’s Mental Health. Topics covered in this issue include, but are not limited to, Psychopharmacology in Pregnancy and Breastfeeding, Binge Eating Disorder, Substance Abuse in Women, Dementia in Women, Neuroendocrine Networks and Functionality, Lesbian and Transgender Mental Health, and Reproductive Rights and Women’s Mental Health.

Handbook of Depression in Alzheimer s Disease

Handbook of Depression in Alzheimer   s Disease
Author: G.S. Smith
Publsiher: IOS Press
Total Pages: 396
Release: 2015-08-05
ISBN: 1614995427
Category: HEALTH & FITNESS
Language: EN, FR, DE, ES & NL

Handbook of Depression in Alzheimer s Disease Book Excerpt:

Advances in healthcare have led to an extended life expectancy throughout the developed world, but cognitive impairment in later life, and Alzheimer's disease (AD) in particular, remains one of the intractable problems which can blight quality of life as we age. Depression in Alzheimer's disease is an additional factor which has a significant impact on disability, disease progression, and caregiver burden. This book, volume 4 of the Advances in Alzheimer’s Disease book series which is published in coordination with the Journal of Alzheimer’s Disease, presents papers which reflect the progress in recent years of research into depression in AD. This research has focused on several areas, including the improvement of diagnostic criteria and outcome measures for depression and depressive symptoms in AD, genetic and imaging studies to elucidate the neurobiological mechanisms, and clinical trials of antidepressants. The book is divided into sections on phenomenology, epidemiology, neuropsychology, neurobiology and neuropathology, neuroimaging, genetics, and treatment. Providing a stimulus to further research in this challenging area by engaging both basic and clinical researchers, this book will be of interest to all those whose work involves understanding and dealing with depression in those suffering from Alzheimer's disease.

Bridging Gaps Between Sex and Gender in Neurosciences

Bridging Gaps Between Sex and Gender in Neurosciences
Author: Annie Duchesne,Meng-Chuan Lai,Gillian Einstein,Belinda Pletzer,Marina A. Pavlova
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-07-14
ISBN: 2889638650
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Bridging Gaps Between Sex and Gender in Neurosciences Book Excerpt:

Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer s Disease

Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer   s Disease
Author: Marilyn J. Duncan,Phyllis Zee,Sigrid Veasey
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-10-22
ISBN: 2889715388
Category: Science
Language: EN, FR, DE, ES & NL

Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer s Disease Book Excerpt:

Information Processing in Medical Imaging

Information Processing in Medical Imaging
Author: Aasa Feragen,Stefan Sommer,Julia Schnabel,Mads Nielsen
Publsiher: Springer Nature
Total Pages: 782
Release: 2021-06-20
ISBN: 3030781917
Category: Computers
Language: EN, FR, DE, ES & NL

Information Processing in Medical Imaging Book Excerpt:

This book constitutes the proceedings of the 27th International Conference on Information Processing in Medical Imaging, IPMI 2021, which was held online during June 28-30, 2021. The conference was originally planned to take place in Bornholm, Denmark, but changed to a virtual format due to the COVID-19 pandemic. The 59 full papers presented in this volume were carefully reviewed and selected from 200 submissions. They were organized in topical sections as follows: registration; causal models and interpretability; generative modelling; shape; brain connectivity; representation learning; segmentation; sequential modelling; learning with few or low quality labels; uncertainty quantification and generative modelling; and deep learning.

Sex Hormone Fluctuations Across the Female Lifespan Mechanisms of Action on Brain Structure Function and Behavior

Sex Hormone Fluctuations Across the Female Lifespan  Mechanisms of Action on Brain Structure  Function  and Behavior
Author: Stephanie V. Koebele,Caitlin M. Taylor,Alexandra Ycaza Herrera,Claudia Barth,Jaclyn M. Schwarz
Publsiher: Frontiers Media SA
Total Pages: 173
Release: 2022-08-02
ISBN: 2889766896
Category: Science
Language: EN, FR, DE, ES & NL

Sex Hormone Fluctuations Across the Female Lifespan Mechanisms of Action on Brain Structure Function and Behavior Book Excerpt:

Postmenopausal Diseases and Disorders

Postmenopausal Diseases and Disorders
Author: Faustino R. Pérez-López
Publsiher: Springer
Total Pages: 484
Release: 2019-07-10
ISBN: 3030139360
Category: Medical
Language: EN, FR, DE, ES & NL

Postmenopausal Diseases and Disorders Book Excerpt:

Supported by the latest scientific data, this book serves as a guide to the clinical assessment of women’s health during the second half of life (post-reproductive years), including approaches to the management of the most frequent age-related diseases and disorders and the most recent advances in treatment. In addition, it discusses preventive aspects of healthcare in post-reproductive women, identifying lifestyle measures to enhance healthy aging. By highlighting research gaps, it promotes the development of quick and easy-to-use assessment tools and predictive markers of age-related co-morbidities. As such, the book is a valuable resource for researchers and clinicians alike.

Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities

Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities
Author: Vee P. Prasher
Publsiher: Springer
Total Pages: 311
Release: 2017-09-19
ISBN: 3319617206
Category: Medical
Language: EN, FR, DE, ES & NL

Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities Book Excerpt:

This fully updated and expanded second edition of a successful book reviews the most important neuropsychological measures currently used in the assessment of dementia by the principal clinicians and researchers associated with the tests. Several clinicians and research workers, who have been at the forefront in developing the tests in question, provide clear practical guidance on the scope of each test, use in research, as well as an analysis of their accuracy and limitations. The international contributors have brought together a concise and practical guide on the role of neuropsychological testing to support the dementia assessment. Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities, Second Edition is an essential reference for all those working in the field of dementia and intellectual disabilities.

Handbook of Microbiome and Gut Brain Axis in Alzheimer s Disease

Handbook of Microbiome and Gut Brain Axis in Alzheimer   s Disease
Author: G.M. Pasinetti
Publsiher: IOS Press
Total Pages: 732
Release: 2022-07-05
ISBN: 164368289X
Category: Medical
Language: EN, FR, DE, ES & NL

Handbook of Microbiome and Gut Brain Axis in Alzheimer s Disease Book Excerpt:

Despite being confined to the gastrointestinal tract, the gut microbiome has a wide impact on human physiology, supplementing its host’s biochemistry in a complex symbiotic relationship. Research in the field has evolved rapidly in the last decade, and we are now developing a better understanding of how our gut microbiome can influence our immune systems, metabolism, neurological signaling, and perhaps most unexpectedly, our brains; a phenomenon described as the gut-brain-axis. This book, ‘Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease’, sets out to explore the complex role of the microbiome with regard to Alzheimer’s disease (AD). The microbiome is a critical and often overlooked aspect of immunity, which in turn plays a role in cognition. The book presents current research into the gut microbiota and its far-reaching impacts on cognitive function and neurodegeneration. Interventions, including probiotic supplementation, fecal transfer, and supplementation with microbial metabolites, are discussed, as is the use of certain probiotics to study the effects of the gut microbiota on behavior and cognitive function, and as potential therapeutics for AD. Other topics covered include the influence of the gut and oral microbiota on immune inflammatory signals: cytokines, neuroendocrine hormones, bacterial components, neuroactive molecules, and microbial metabolites. The book is divided into four sections, each covering a research area pertinent to the gut-brain-axis and its relationship with cognitive function and AD. It will be of interest to all those whose work includes the study and understanding of these complex, multi-variable biological mechanisms, particularly in the context of cognitive function and AD. The cover shows a color edited MRI image of a sagittal section of a neurological control brain of Dr. Giulio Maria Pasinetti.

Applied Neurotoxicology An Issue of Neurologic Clinics E Book

Applied Neurotoxicology An Issue of Neurologic Clinics E Book
Author: Michael R. Dobbs,Mam I. Ibraheem
Publsiher: Elsevier Health Sciences
Total Pages: 240
Release: 2020-10-23
ISBN: 0323712924
Category: Medical
Language: EN, FR, DE, ES & NL

Applied Neurotoxicology An Issue of Neurologic Clinics E Book Book Excerpt:

This issue of Neurologic Clinics, guest edited by Drs. Michael R. Dobbs and Mam I. Ibraheem, is devoted to Applied Neurotoxicology. This issue is one of four selected each year by the series Consulting Editor, Dr. Randolph W. Evan. Articles in this issue include: Peripheral Neuropathy, Toxin-induced Channelopathies and Neuromuscular Junction Disorders, Myopathy, Acute delirium, Subacute Encephalopathy, Coma and CNS depression, Cerebellar disorders, Parkinsonism, Seizures, Amyotrophic Lateral Sclerosis, Neurobiological Weapons, Women’s and Fetal Issues in Neurotoxicology, and Ethical Dilemmas in Neurotoxicology.

Molecular Biology of Aging

Molecular Biology of Aging
Author: Anonim
Publsiher: Academic Press
Total Pages: 392
Release: 2017-02-18
ISBN: 0128115335
Category: Science
Language: EN, FR, DE, ES & NL

Molecular Biology of Aging Book Excerpt:

Molecular Biology of Aging, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on placental development and disease. Contains contributions from leading authorities on the topic Publishes cutting-edge reviews in molecular biology