Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease

Sialic Acids and Sialoglycoconjugates in the Biology of Life  Health and Disease
Author: Shyamasree Ghosh
Publsiher: Academic Press
Total Pages: 362
Release: 2020-01-08
ISBN: 0128161272
Category: Science
Language: EN, FR, DE, ES & NL

Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease Book Excerpt:

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. Discusses the sialic acids and their role in different diseases (other than cancer) Provides an understanding of sialylations as post translational modifications (PTM) Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health Gives insights on the importance of sialic acid biology through animal models

Immunogenetics A Molecular and Clinical Overview

Immunogenetics  A Molecular and Clinical Overview
Author: Muneeb U. Rehman,Azher Arafah,Md. Niamat Ali,Shafat Ali
Publsiher: Academic Press
Total Pages: 410
Release: 2021-11-30
ISBN: 0323903355
Category: Medical
Language: EN, FR, DE, ES & NL

Immunogenetics A Molecular and Clinical Overview Book Excerpt:

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. Contains exclusive information about research on immunogenetics from around the globe Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Organelle and Molecular Targeting

Organelle and Molecular Targeting
Author: Lara Scheherazade Milane,Mansoor M. Amiji
Publsiher: CRC Press
Total Pages: 510
Release: 2021-12-29
ISBN: 1000505936
Category: Science
Language: EN, FR, DE, ES & NL

Organelle and Molecular Targeting Book Excerpt:

We have surpassed the omics era and are truly in the Age of Molecular Therapeutics. The fast-paced development of SARS-CoV-2 vaccines, such as the mRNA vaccines encoding the viral spike protein, demonstrated the need for and capability of molecular therapy and nanotechnology-based solutions for drug delivery. In record speed, the SARS-CoV-2 viral RNA genome was sequenced and shared with the scientific community, allowing the rapid design of molecular therapeutics. The mRNA vaccines exploit the host cell endoplasmic reticulum to produce viral spike proteins for antigen presentation and recognition by the innate and adaptive immune system. Lipid nanoparticles enable the delivery of the fragile, degradation-sensitive nucleic acid payloads. Molecular-based therapeutics and nanotechnology solutions continue to drive the scientific and medical response to the COVID-19 pandemic as new mRNA, DNA, and protein-based vaccines are developed and approved and the emergency use approved vaccines are rapidly manufactured and distributed throughout the globe. The need for molecular therapies and drug delivery solutions is clear, and as these therapies progress and become more specialized there will be important advancements in organelle targeting. For example, using organelle targeting to direct lipid nanoparticles with mRNA payloads to the endoplasmic reticulum would increase the efficacy of mRNA vaccines, reducing the required dose and therefore the biomanufacturing demand. Likewise, improving the delivery of DNA therapeutics to the nucleus would improve efficacy. Organelles and molecules have always been drug targets, but until recently we have not had the tools or capability to design and develop such highly specific therapeutics. Organelle targeting has far-reaching implications. For example, mitochondria are central to both energy production and intrinsic apoptosis. Effectively targeting and manipulating mitochondria has therapeutic applications for diseases such as myopathies, cancer, neurodegeneration, progerias, diabetes, and the natural aging process. The SARS-CoV-2 vaccines that exploit the endoplasmic reticulum (for mRNA vaccines) and the nucleic translational process (DNA vaccines) attest to the need for organelle and molecular therapeutics. This book covers the status, demand, and future of organelle- and molecularly targeted therapeutics that are critical to the advancement of modern medicine. Organelle and molecular targeting is the drug design and drug delivery approach of today and the future; understanding this approach is essential for students, scientists, and clinicians contributing to modern medicine.

Stem Cells

Stem Cells
Author: Suchandra Chowdhury,Shyamasree Ghosh
Publsiher: Springer Nature
Total Pages: 266
Release: 2021-07-24
ISBN: 9811616388
Category: Science
Language: EN, FR, DE, ES & NL

Stem Cells Book Excerpt:

Stem cells hold great promise for cell therapy, tissue engineering, regenerative medicine and pharmaceutical and biotechnological applications. This book highlights the potency of stem cells, their property of self-renewal and their ability to differentiate into different cell lineages. It further describes the different markers to identify stem cells, sources, methods of isolation, culture including 2D, 3D and beyond and their cryopreservation. This is among the first books to discuss glycosylation and sialylation in stem cells. Chapters describe application of stem cells in regenerative medicine and therapy, and highlight their application in cancer therapy and spinal cord injury. The book talks about the important patents on stem cells. The book also highlights the plant stem cells, discussing their pluoripotent nature, role in organ regeneration after injury, specific stem cell niches, that signals to block differentiation studied in plants shoot, root, and vascular meristems, differentiation of plant stem cell, transcriptional regulation and epigenetic modification of plant stem cells. This book is exciting and cutting edge. It will be of great interest to doctors, students and researchers in the field of regenerative medicine, cancer , biotechnology and plant sciences.

Edible Birds Nest Chemical Composition and Potential Health Efficacy and Risks

Edible Birds Nest   Chemical Composition and Potential Health Efficacy and Risks
Author: Karl Tsim,Ting Hun Lee,Geng Li,Gallant Chan
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-02-23
ISBN: 2889744914
Category: Science
Language: EN, FR, DE, ES & NL

Edible Birds Nest Chemical Composition and Potential Health Efficacy and Risks Book Excerpt:

Dietary Carbohydrate Digestibility and Metabolic Effects in Human Health

Dietary Carbohydrate Digestibility and Metabolic Effects in Human Health
Author: F. Javier Moreno,Oswaldo Hernandez-Hernandez,Robert Rastall
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2019-12-09
ISBN: 2889632318
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Dietary Carbohydrate Digestibility and Metabolic Effects in Human Health Book Excerpt:

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1999
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Excerpt:

Issues in Immunology Research 2013 Edition

Issues in Immunology Research  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 1230
Release: 2013-05-01
ISBN: 1490107223
Category: Medical
Language: EN, FR, DE, ES & NL

Issues in Immunology Research 2013 Edition Book Excerpt:

Issues in Immunology Research / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Immunochemistry. The editors have built Issues in Immunology Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunochemistry in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research / 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Machine Learning in Biological Sciences

Machine Learning in Biological Sciences
Author: Shyamasree Ghosh
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN: 9811688818
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Machine Learning in Biological Sciences Book Excerpt:

Index Medicus

Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2002
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Index Medicus Book Excerpt:

Dissertation Abstracts International

Dissertation Abstracts International
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1989
ISBN: 1928374650XXX
Category: Dissertations, Academic
Language: EN, FR, DE, ES & NL

Dissertation Abstracts International Book Excerpt: