Spine Phenotypes

Spine Phenotypes
Author: Dino Samartzis,Jaro I. Karppinen,Frances M.K. Williams
Publsiher: Academic Press
Total Pages: 416
Release: 2022-07-08
ISBN: 0128227796
Category: Science
Language: EN, FR, DE, ES & NL

Spine Phenotypes Book Excerpt:

The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance. Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications. Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry. Book chapters devoted to specific imaging phenotypes with discussion of their clinical correlates Imaging phenotypes provided with examples of established phenotypic measurements and a range of normal and pathologic images Multiauthor, multidisciplinary contributions comprising world leaders in the field of spine imaging, research, and clinical practice

Atlas of Spinal Imaging Phenotypes

Atlas of Spinal Imaging Phenotypes
Author: Philip Louie,Howard S. An,Dino Samartzis
Publsiher: Elsevier Health Sciences
Total Pages: 282
Release: 2021-03-23
ISBN: 0323761127
Category: Medical
Language: EN, FR, DE, ES & NL

Atlas of Spinal Imaging Phenotypes Book Excerpt:

Spine-related pain is the world’s leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging Phenotypes: Classifications and Radiographic Measurements is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. Helps readers better understanding spinal phenotypes and their imaging, and how today’s knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. Includes validated classification systems that complement the phenotypes and radiographic measurements. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.

Dendritic spines from shape to function

Dendritic spines  from shape to function
Author: Nicolas Heck,Ruth Benavides-Piccione
Publsiher: Frontiers Media SA
Total Pages: 237
Release: 2016-02-03
ISBN: 2889197662
Category: Cerebral cortex
Language: EN, FR, DE, ES & NL

Dendritic spines from shape to function Book Excerpt:

One fundamental requisite for a comprehensive view on brain function and cognition is the understanding of the neuronal network activity of the brain. Neurons are organized into complex networks, interconnected through synapses. The main sites for excitatory synapses in the brain are thin protrusions called dendritic spines that emerge from dendrites. Dendritic spines have a distinct morphology with a specific molecular organization. They are considered as subcellular compartments that constrain diffusion and influence signal processing by the neuron and, hence, spines are functional integrative units for which morphology and function are tightly coupled. The density of spines along the dendrite reflects the levels of connectivity within the neuronal network. Furthermore, the relevance of studying dendritic spines is emphasized by the observation that their morphology changes with synaptic plasticity and is altered in many psychiatric disorders. The present Research Topic deals with some of the most recent findings concerning dendritic spine structure and function, showing that, in order to understand how brain neuronal activity operates, these two factors should be regarded as being intrinsically linked.

Issues in Biological and Life Sciences Research 2013 Edition

Issues in Biological and Life Sciences Research  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 1193
Release: 2013-05-01
ISBN: 1490108688
Category: Science
Language: EN, FR, DE, ES & NL

Issues in Biological and Life Sciences Research 2013 Edition Book Excerpt:

Issues in Biological and Life Sciences Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Issues in Biological and Life Sciences Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Canadian Journal of Zoology

Canadian Journal of Zoology
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2001
ISBN: 1928374650XXX
Category: Electronic journals
Language: EN, FR, DE, ES & NL

Canadian Journal of Zoology Book Excerpt:

The Growing Spine

The Growing Spine
Author: Behrooz A. Akbarnia,Muharrem Yazici,George H. Thompson
Publsiher: Springer
Total Pages: 949
Release: 2015-11-02
ISBN: 3662482843
Category: Medical
Language: EN, FR, DE, ES & NL

The Growing Spine Book Excerpt:

The second edition of The Growing Spine has been extensively revised to cover recent advances in knowledge and management. The book is intended as a comprehensive, one-stop reference for specialists and health professionals who care for young children with spinal deformities. In addition, it will effectively help to standardize the care of these patients. Depending on the etiology, children with spinal deformities are often cared for by multiple specialists, including pediatricians, pediatric orthopaedists or orthopaedic spine surgeons, neurologists, pediatric surgeons, pediatric neurosurgeons, oncologists, and pulmonologists. The multidisciplinary nature of care is reflected in The Growing Spine, which will be of value for all involved practitioners rather than just orthopaedic specialists. It will also be an ideal reference for nurses, physical therapists, and healthcare professionals in training, who are usually unfamiliar with spinal deformities in children.

Diagnostic Imaging Spine E Book

Diagnostic Imaging  Spine E Book
Author: Jeffrey S. Ross,Kevin R. Moore
Publsiher: Elsevier Health Sciences
Total Pages: 1100
Release: 2015-08-21
ISBN: 0323400604
Category: Medical
Language: EN, FR, DE, ES & NL

Diagnostic Imaging Spine E Book Book Excerpt:

With constant improvements to MR image quality, it's important to have a resource reflecting the most recent developments. Diagnostic Imaging: Spine, now in its third edition, showcases the latest cutting-edge research from Dr. Jeffrey Ross and his team of experts in the field. Expanding upon the core of the highly popular second edition, this updated reference is fully revised to provide the best spine-related diagnostic support available. Covers the latest advancements in imaging the postoperative spine, including bone morphogenetic protein (BMP) utilization Includes additional genetic information, such as OMIM entry numbers, where appropriate Highlights updates to new classification and grading schemes Hundreds of full-color pathology images are carefully annotated to help pinpoint the most relevant factors New references direct you to additional trustworthy resources Bulleted lists provide guidance through the intricacies of the spine Presents brand new images and cases to keep you at the forefront of your field Medicine eBook is accessible on a variety of devices

Diagnostic Imaging Spine E Book

Diagnostic Imaging  Spine   E Book
Author: Jeffrey S. Ross,Kevin R. Moore
Publsiher: Elsevier Health Sciences
Total Pages: 1250
Release: 2020-11-16
ISBN: 0323794009
Category: Medical
Language: EN, FR, DE, ES & NL

Diagnostic Imaging Spine E Book Book Excerpt:

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Spine, fourth edition, is an invaluable resource for general radiologists, neuroradiologists, and trainees—anyone who requires an easily accessible, highly visual reference on today’s spinal imaging. Drs. Jeffrey Ross, Kevin Moore, and their team of highly regarded experts provide updated information on disease identification and imaging techniques to help you make informed decisions at the point of care. The text is lavishly illustrated, delineated, and referenced, making it a useful learning tool as well as a handy reference for daily practice. Serves as a one-stop resource for key concepts and information on radiologic imaging and interpretation of spine, spinal cord, and bony vertebral conditions Features more than 2,600 full-color illustrations, including radiologic, pathologic, and clinical images Contains new chapters on recent surgery protocols such as spine instability neoplastic scoring (SINS) and epidural spinal cord compression scale (ESSC) Features updates from cover to cover including revisions in accordance with new information on inflammatory and autoimmune disorders and systemic manifestations of diseases Provides expanded imaging details for metastatic diseases to accommodate recent significant changes, including new categories of oncologic surgery driven by the use of proton beam radiotherapy, PET MR as a diagnostic modality, and new FDA-approved hardware Includes new information on areas of demyelinating diseases related to better understanding of MS, neuromyelitis optica spectrum disorder, and anti-MOG disorders; a variety of spinal CSF leak pathologies that cause intracranial hypotension; genetic and disease information on schwannomatosis; and much more Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care

Some Effects of the White Spine Uniform Color and Gynoecious Alleles on Quality and Certain Other Characters in the Cucumber Variety Wisconsin SMR 18

Some Effects of the White Spine  Uniform Color and Gynoecious Alleles on Quality and Certain Other Characters in the Cucumber Variety Wisconsin SMR 18
Author: Benjamin Franklin George
Publsiher: Unknown
Total Pages: 226
Release: 1971
ISBN: 1928374650XXX
Category: Cucumbers
Language: EN, FR, DE, ES & NL

Some Effects of the White Spine Uniform Color and Gynoecious Alleles on Quality and Certain Other Characters in the Cucumber Variety Wisconsin SMR 18 Book Excerpt:

Atlas of Spinal Imaging

Atlas of Spinal Imaging
Author: Philip K. Louie, MD,Howard S. An, MD,Dino Samartzis
Publsiher: Unknown
Total Pages: 400
Release: 2021-02
ISBN: 9780323761116
Category: Medical
Language: EN, FR, DE, ES & NL

Atlas of Spinal Imaging Book Excerpt:

Spine-related pain is the world's leading disabling condition, affecting every population and a frequent reason for seeking medical consultation and obtaining imaging studies. Numerous spinal phenotypes (observations/traits) and their respective measurements performed on various spine imaging have been shown to directly correlate and predict clinical outcomes. Atlas of Spinal Imaging Phenotypes: Classifications and Radiographic Measurements is a comprehensive visual resource that highlights various spinal phenotypes on imaging, describes their clinical and pathophysiological relevance, and discusses and illustrates their respective measurement techniques and classifications. Helps readers better understanding spinal phenotypes and their imaging, and how today's knowledge will facilitate new targeted drug discovery, novel diagnostics and biomarker discovery, and outcome predictions. Features step-by-step instructions on performing the radiographic measurements with examples of normal and pathologic images to demonstrate the various presentations. Presents clinical correlation of the phenotypes as well as the radiographic measurements with landmark references. Includes validated classification systems that complement the phenotypes and radiographic measurements. Complies the knowledge and expertise of Dr. Dino Samartzis, the preeminent global authority on spinal phenotypes who has discovered and proposed new phenotypes and classification schemes; Dr. Howard S. An, a leading expert in patient management and at the forefront of 3D imaging of various spinal phenotypes; and Dr. Philip Louie, a prolific surgeon who is involved in one of the largest machine learning initiatives of spinal phenotyping.

Fishery Bulletin

Fishery Bulletin
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1974
ISBN: 1928374650XXX
Category: Fisheries
Language: EN, FR, DE, ES & NL

Fishery Bulletin Book Excerpt:

Environmental Experience and Plasticity of the Developing Brain

Environmental Experience and Plasticity of the Developing Brain
Author: Alessandro Sale
Publsiher: John Wiley & Sons
Total Pages: 240
Release: 2016-02-04
ISBN: 1118931661
Category: Medical
Language: EN, FR, DE, ES & NL

Environmental Experience and Plasticity of the Developing Brain Book Excerpt:

Environmental Experience and Plasticity of the Developing Brain goes beyond the genetic basis of neurodevelopment. Chapters illuminate the external factors that can dramatically impact the brain early in life and, consequently, the eventual accomplishment of developmental milestones and the construction of adult behavior and personality. Authored and edited by leaders in this rapidly growing field, Environmental Experience and Plasticity of the Developing Brain not only surveys preexisting literature on the effects of environment versus genetics, but also discusses more recent studies on the impacts of neurodevelopment in terms of maternal stimulation, environmental enrichment and sensory deprivation. The book also includes key examples of environmental impacts on preexisting genetic syndromes leading to developmental disabilities. Focus is also given to the consequences of early adverse experience in primates, as well as neurobiological and behavioral consequences in institutionalized human children and the reversibility of such consequences. Environmental Experience and Plasticity of the Developing Brain encompasses a broad area of research in the field of developmental neurobiology and offers a unique combination of different examples of environmental factors affecting brain development and behavior.

Neural Stem Cells for Brain and Spinal Cord Repair

Neural Stem Cells for Brain and Spinal Cord Repair
Author: Tanja Zigova
Publsiher: Springer Science & Business Media
Total Pages: 434
Release: 2002-11-05
ISBN: 1592592988
Category: Medical
Language: EN, FR, DE, ES & NL

Neural Stem Cells for Brain and Spinal Cord Repair Book Excerpt:

Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.

Genetically Modified Organisms and Genetic Engineering in Research and Therapy

Genetically Modified Organisms and Genetic Engineering in Research and Therapy
Author: Pascale Piguet,P. Poindron,Philippe Poindron
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 138
Release: 2012
ISBN: 3805590652
Category: Science
Language: EN, FR, DE, ES & NL

Genetically Modified Organisms and Genetic Engineering in Research and Therapy Book Excerpt:

Genetically modified organisms (GMO) raise societal, political and ethical concerns. They inspire strong resistance or, conversely, enthusiastic assent. The aim of this publication is to give an overview of genetic engineering, starting with the history of the discovery of restriction enzymes continuing with technical aspects of transgenesis to its applications in research and ethical considerations. Be it the use of single engineered cells or GMO, these applications cover a broad array, ranging from disease-oriented research (but not only), to the promising perspectives of gene therapy. Historical and technical aspects give insights into the problems inherent to the creation of GMO, and illustrate the links and limits between genetic engineering, GMOs and gene therapy. A summary article in English and French structures the links between the different chapters and concepts. Scientists interested in genetic engineering of single cells or animal models, as well as in gene therapy, will find an up-to-date review on the use and perspectives of transgenesis. However, this publication is also recommended to the public interested in the definition of GMO, which encompasses a much broader array than the genetically modified crops covered by media.

Synaptic Assembly and Neural Circuit Development

Synaptic Assembly and Neural Circuit Development
Author: Jaewon Ko,Chen Zhang
Publsiher: Frontiers Media SA
Total Pages: 191
Release: 2018-11-02
ISBN: 2889456307
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Synaptic Assembly and Neural Circuit Development Book Excerpt:

Modulating Glial Cells Phenotype New Findings and Therapies

Modulating Glial Cells Phenotype  New Findings and Therapies
Author: Alberto Javier Ramos,Yolanda Diz-Chaves,Maria Jose Bellini
Publsiher: Frontiers Media SA
Total Pages: 178
Release: 2020-12-21
ISBN: 2889661830
Category: Science
Language: EN, FR, DE, ES & NL

Modulating Glial Cells Phenotype New Findings and Therapies Book Excerpt:

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Epidemiology of Brain and Spinal Tumors

Epidemiology of Brain and Spinal Tumors
Author: Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Publsiher: Academic Press
Total Pages: 552
Release: 2021-04-16
ISBN: 0128217553
Category: Medical
Language: EN, FR, DE, ES & NL

Epidemiology of Brain and Spinal Tumors Book Excerpt:

Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Pathological Hyperactivity and Hyperexcitability in the Central Nervous System

Pathological Hyperactivity and Hyperexcitability in the Central Nervous System
Author: Michael Telias,Menahem Segal,Alexander Galazyuk
Publsiher: Frontiers Media SA
Total Pages: 130
Release: 2022-08-05
ISBN: 2889767280
Category: Science
Language: EN, FR, DE, ES & NL

Pathological Hyperactivity and Hyperexcitability in the Central Nervous System Book Excerpt:

First International Pineapple Symposium

First International Pineapple Symposium
Author: Duane Phillip Bartholomew,Kenneth G. Rohrbach
Publsiher: Unknown
Total Pages: 471
Release: 1993
ISBN: 1928374650XXX
Category: Pineapple
Language: EN, FR, DE, ES & NL

First International Pineapple Symposium Book Excerpt:

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
Author: Carlo Sala,Chiara Verpelli
Publsiher: Academic Press
Total Pages: 394
Release: 2016-04-30
ISBN: 0128005335
Category: Medical
Language: EN, FR, DE, ES & NL

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability Book Excerpt:

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture