Spontaneous Pathology of the Laboratory Non human Primate

Spontaneous Pathology of the Laboratory Non human Primate
Author: Alys E Bradley,Jennifer Chilton
Publsiher: Academic Press
Total Pages: 575
Release: 2019-06-15
ISBN: 9780128130889
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Spontaneous Pathology of the Laboratory Non human Primate Book Excerpt:

Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. By providing that background information, this text solves that problem. This book serves as a "go to" text for all pathologists working on primates in safety assessment studies, and to help diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these species in zoological collections. Primate species included are rhesus and cynomolgus macaques, and marmosets. Multi-authored chapters are arranged by organ system. Comprehensive text that describes the spontaneous pathology seen in the common laboratory primate species: rhesus and cynomolgus macaques, and marmosets Color illustrations depict the most common lesions to augment the descriptions Descriptions are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP), and currently utilized in rodent manuscripts published in the Japanese Journal of Toxicological Pathology and the Journal of Toxicologic Pathology Provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
Author: Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
Publsiher: Academic Press
Total Pages: 716
Release: 2015-03-13
ISBN: 012417146X
Category: Medical
Language: EN, FR, DE, ES & NL

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment Book Excerpt:

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

Haschek and Rousseaux s Handbook of Toxicologic Pathology

Haschek and Rousseaux s Handbook of Toxicologic Pathology
Author: Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig,Brad Bolon
Publsiher: Academic Press
Total Pages: 1152
Release: 2021-10-20
ISBN: 0128218290
Category: Medical
Language: EN, FR, DE, ES & NL

Haschek and Rousseaux s Handbook of Toxicologic Pathology Book Excerpt:

Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Spontaneous Pathology of the Laboratory Rabbit

Spontaneous Pathology of the Laboratory Rabbit
Author: Alys Bradley
Publsiher: Academic Press
Total Pages: 575
Release: 2022-01-17
ISBN: 9780128225288
Category: Science
Language: EN, FR, DE, ES & NL

Spontaneous Pathology of the Laboratory Rabbit Book Excerpt:

Provides a comprehensive text describing the spontaneous pathology seen in the common laboratory rabbit strains. This is the first book collating information on all organ systems in these strains. Rabbits are widely used for experimentation and testing mainly due to practical, rather than scientific, considerations. They are small and usually docile, easily restrained, cheap to maintain, and breed prodigious. Spontaneous Pathology of the Laboratory Rabbit serves as a "go to” text for all pathologists working on laboratory rabbits in safety assessment studies, and to help diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these animals which are also kept as domestic pets. Consist of multi-author chapters arranged by Organ systems Provides color illustrations that depict the most common lesions to augment the descriptions provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines Gives references for recommended tissue trimming planes

The Utilization of Non human Primates in Radiologic Research

The Utilization of Non human Primates in Radiologic Research
Author: Sam Silverman
Publsiher: Unknown
Total Pages: 136
Release: 1983
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

The Utilization of Non human Primates in Radiologic Research Book Excerpt:

Conn s Handbook of Models for Human Aging

Conn s Handbook of Models for Human Aging
Author: Jeffrey L. Ram,P. Michael Conn
Publsiher: Academic Press
Total Pages: 1218
Release: 2018-04-05
ISBN: 0128113545
Category: Medical
Language: EN, FR, DE, ES & NL

Conn s Handbook of Models for Human Aging Book Excerpt:

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research
Author: Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publsiher: Academic Press
Total Pages: 868
Release: 2012-04-12
ISBN: 0123813662
Category: Medical
Language: EN, FR, DE, ES & NL

Nonhuman Primates in Biomedical Research Book Excerpt:

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

Subject Index of Current Research Grants and Contracts Administered by the National Heart Lung and Blood Institute

Subject Index of Current Research Grants and Contracts Administered by the National Heart  Lung and Blood Institute
Author: National Heart, Lung, and Blood Institute
Publsiher: Unknown
Total Pages: 135
Release: 1976
ISBN: 1928374650XXX
Category: Cardiovascular research
Language: EN, FR, DE, ES & NL

Subject Index of Current Research Grants and Contracts Administered by the National Heart Lung and Blood Institute Book Excerpt:

Biomarkers in Toxicology

Biomarkers in Toxicology
Author: Ramesh C. Gupta
Publsiher: Academic Press
Total Pages: 1246
Release: 2019-02-13
ISBN: 0128146567
Category: Medical
Language: EN, FR, DE, ES & NL

Biomarkers in Toxicology Book Excerpt:

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

CRC Handbook of Laboratory Animal Science

CRC Handbook of Laboratory Animal Science
Author: Edward C. Melby,Norman H. Altman
Publsiher: Unknown
Total Pages: 135
Release: 1974
ISBN: 1928374650XXX
Category: Animal experimentation
Language: EN, FR, DE, ES & NL

CRC Handbook of Laboratory Animal Science Book Excerpt:

Nephrotoxicity in the experimental and clinical situation

Nephrotoxicity in the experimental and clinical situation
Author: P.H. Bach,E.A. Lock
Publsiher: Springer Science & Business Media
Total Pages: 488
Release: 2012-12-06
ISBN: 9400933673
Category: Medical
Language: EN, FR, DE, ES & NL

Nephrotoxicity in the experimental and clinical situation Book Excerpt:

Nonhuman Primates in Biomedical Research Two Volume Set

Nonhuman Primates in Biomedical Research Two Volume Set
Author: Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publsiher: Academic Press
Total Pages: 1200
Release: 2012-12-31
ISBN: 0124159729
Category: Science
Language: EN, FR, DE, ES & NL

Nonhuman Primates in Biomedical Research Two Volume Set Book Excerpt:

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The publication emphasizes the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information

ILAR News

ILAR News
Author: Institute of Laboratory Animal Resources (U.S.)
Publsiher: Unknown
Total Pages: 135
Release: 1967
ISBN: 1928374650XXX
Category: Electronic journals
Language: EN, FR, DE, ES & NL

ILAR News Book Excerpt:

Research Procedures and Data Analysis

Research Procedures and Data Analysis
Author: James Wilson
Publsiher: Springer Science & Business Media
Total Pages: 458
Release: 2013-03-09
ISBN: 1461589398
Category: Science
Language: EN, FR, DE, ES & NL

Research Procedures and Data Analysis Book Excerpt:

The Laboratory Primate

The Laboratory Primate
Author: Anonim
Publsiher: Elsevier
Total Pages: 650
Release: 2005-09-19
ISBN: 9780080454160
Category: Science
Language: EN, FR, DE, ES & NL

The Laboratory Primate Book Excerpt:

A volume in the Handbook of Experimental Animals series, The Laboratory Primate details the past and present use of primates in biomedical research, and the husbandry, nutritional requirements, behaviour, and breeding of each of the commonly used species. Practical information on regulatory requirements, not available in other texts, is covered. Sections on experimental models cover the major areas of biomedical research, including AIDS, cancer, neurobiology and gene therapy. Assisted reproductive technology, tissue typing, and minimum group sizes for infectious disease/vaccine studies are also included. Two-color, user-friendly format, with copious illustrations and color plates Includes detailed, well-illustrated sections on gross & microscopic anatomy, common diseases, and special procedures, including surgical techniques

Pathology of Wildlife and Zoo Animals

Pathology of Wildlife and Zoo Animals
Author: Karen A. Terio,Denise McAloose,Judy St. Leger
Publsiher: Academic Press
Total Pages: 1136
Release: 2018-10-08
ISBN: 012809219X
Category: Science
Language: EN, FR, DE, ES & NL

Pathology of Wildlife and Zoo Animals Book Excerpt:

Pathology of Wildlife and Zoo Animals is a comprehensive resource that covers the pathology of wildlife and zoo species, including a wide scope of animals, disease types and geographic regions. It is the definitive book for students, biologists, scientists, physicians, veterinary clinicians and pathologists working with non-domestic species in a variety of settings. General chapters include information on performing necropsies, proper techniques to meet the specialized needs of forensic cases, laboratory diagnostics, and an introduction into basic principles of comparative clinical pathology. The taxon-based chapters provide information about disease in related groups of animals and include descriptions of gross and histologic lesions, pathogenesis and diagnostics. For each group of animals, notable, unique gross and microscopic anatomical features are provided to further assist the reader in deciding whether differences from the domestic animal paradigm are "normal." Additional online content, which includes text, images, and whole scanned glass slides of selected conditions, expands the published material resulting in a comprehensive approach to the topic. Presents a single resource for performing necropsies on a variety of taxa, including terrestrial and aquatic vertebrates and invertebrates Describes notable, unique gross and microscopic anatomical variations among species/taxa to assist in understanding normal features, in particular those that can be mistaken as being abnormal Provides consistent organization of chapters with descriptions of unique anatomic features, common non-infectious and infectious diseases following brief overviews of the taxonomic group Contains full-color, high quality illustrations of diseases Links to a large online library of scanned slides related to topics in the book that illustrate important histologic findings

Spontaneous and External Radiation Related Tumors in Nonhuman Primates A Survey

Spontaneous and External Radiation Related Tumors in Nonhuman Primates  A Survey
Author: Anonim
Publsiher: Unknown
Total Pages: 28
Release: 1972
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Spontaneous and External Radiation Related Tumors in Nonhuman Primates A Survey Book Excerpt:

A survey was made of the occurrence of spontaneous and external radiation-related tumors in primates. More than 30 tumors related to irradiation exposure and more than 270 spontaneous tumors were found. The 137 literature references concerning these tumors are listed, in two comprehensive tables, according to the location and type of tumor, as well as to the species, sex, and age of the respective primates. (Author).

Biohazards and Zoonotic Problems of Primate Procurement Quarantine and Research

Biohazards and Zoonotic Problems of Primate Procurement  Quarantine and Research
Author: M. L. Simmons
Publsiher: Unknown
Total Pages: 137
Release: 1976
ISBN: 1928374650XXX
Category: Laboratory animals
Language: EN, FR, DE, ES & NL

Biohazards and Zoonotic Problems of Primate Procurement Quarantine and Research Book Excerpt:

Background Lesions in Laboratory Animals E Book

Background Lesions in Laboratory Animals E Book
Author: Elizabeth Fiona McInnes
Publsiher: Elsevier Health Sciences
Total Pages: 256
Release: 2011-10-24
ISBN: 0702049247
Category: Medical
Language: EN, FR, DE, ES & NL

Background Lesions in Laboratory Animals E Book Book Excerpt:

Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

Handbook of Exotic Pet Medicine

Handbook of Exotic Pet Medicine
Author: Marie Kubiak
Publsiher: John Wiley & Sons
Total Pages: 528
Release: 2020-08-24
ISBN: 1119389992
Category: Medical
Language: EN, FR, DE, ES & NL

Handbook of Exotic Pet Medicine Book Excerpt:

Easy-to-use, comprehensive reference covering the less common species encountered in general veterinary practice Handbook of Exotic Pet Medicine provides easy-to-access, detailed information on a wide variety of exotic species that can be encountered in general veterinary practice. Offering excellent coverage of topics such as basic techniques, preventative health measures, and a formulary for each species, each chapter uses the same easy-to-follow format so that users can find information quickly while working in the clinic. Presented in full colour, with over 400 photographs, the book gives small animal practitioners the confidence to handle and treat more familiar pets such as budgerigars, African grey parrots, bearded dragons, corn snakes, tortoises, pygmy hedgehogs, hamsters and rats. Other species that may be presented less frequently including skunks, marmosets, sugar gliders, koi carp, chameleons and terrapins are also covered in detail to enable clinicians to quickly access relevant information. Provides comprehensive coverage of many exotic pet species that veterinarians may encounter in general practice situations Presents evidence-based discussions of topics including biological parameters, husbandry, clinical evaluation, hospitalization requirements, common medical and surgical conditions, radiographic imaging, and more The Handbook of Exotic Pet Medicine is an ideal one-stop reference for the busy general practitioner seeing the occasional exotic animal, veterinary surgeons with an established exotic animal caseload, veterinary students and veterinary nurses wishing to further their knowledge.