Synapse Development and Maturation

Synapse Development and Maturation
Author: Pasko Rakic,John Rubenstein,Bin Chen,Kenneth Y. Kwan
Publsiher: Academic Press
Total Pages: 558
Release: 2020-05-29
ISBN: 0128236736
Category: Science
Language: EN, FR, DE, ES & NL

Synapse Development and Maturation Book Excerpt:

Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

Methods in Neurotransmitter and Neuropeptide Research

Methods in Neurotransmitter and Neuropeptide Research
Author: S.H. Parvez,M. Naoi,T. Nagatsu
Publsiher: Elsevier
Total Pages: 436
Release: 2013-10-22
ISBN: 1483290220
Category: Science
Language: EN, FR, DE, ES & NL

Methods in Neurotransmitter and Neuropeptide Research Book Excerpt:

This two-part book provides the most advanced biochemical and histochemical analytical methods on neurotransmitters, neuromodulators, and neuropeptides described by international specialists. The biochemical methods include liquid chromatography/electrochemistry, liquid chromatography/fluorescence and chemiluminescence detection, gas chromatography or liquid chromatography with mass spectrometry, and immunoassays. Morphological and physiological methods are also described, including immunohistochemistry, in situ hybridization, in vivo microdialysis, electrophysiological analysis, microwave irradiation, electrophysiological analysis, micro-anatomical dissection, peptide sequence analysis, quantitative autoradiographic analysis, and isolated CNS preparations. The neurotransmitters and neuropeptides include catecholamines, indoleamines, histamine, polyamines, and various neuropeptides, and their related enzymes. The book is the most comprehensive, advanced and versatile volume on the biochemical, morphological and physiological analysis of neurotransmitters and neuropeptides.

Molecular Mechanisms of Neural Development and Insights into Disease

Molecular Mechanisms of Neural Development and Insights into Disease
Author: Anonim
Publsiher: Academic Press
Total Pages: 546
Release: 2021-03-09
ISBN: 0128152826
Category: Science
Language: EN, FR, DE, ES & NL

Molecular Mechanisms of Neural Development and Insights into Disease Book Excerpt:

Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord, The role of astrocytes in synapse formation and maturation, Development of motor circuits, Molecular mechanisms that mediate dendrite morphogenesis, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series

The Fragile X Syndrome Where Do We Go

The Fragile X Syndrome     Where Do We Go
Author: Regina Dahlhaus,Christian Gonzalez-Billault
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-12-22
ISBN: 288971845X
Category: Science
Language: EN, FR, DE, ES & NL

The Fragile X Syndrome Where Do We Go Book Excerpt:

Developmental Neurobiology

Developmental Neurobiology
Author: Greg Lemke
Publsiher: Academic Press
Total Pages: 771
Release: 2010-05-22
ISBN: 9780123751676
Category: Science
Language: EN, FR, DE, ES & NL

Developmental Neurobiology Book Excerpt:

Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject. The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook information The 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the Encyclopedia of Neuroscience by one of the great developmental neuroscientists, Greg Lemke The best researchers in the field provide their conclusions in the context of the latest experimental results

The Dynamic Synapse

The Dynamic Synapse
Author: Josef T. Kittler,Stephen J. Moss
Publsiher: CRC Press
Total Pages: 336
Release: 2006-03-27
ISBN: 0203486285
Category: Science
Language: EN, FR, DE, ES & NL

The Dynamic Synapse Book Excerpt:

Exploring the diverse tools and technologies used to study synaptic processes, The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology delineates techniques, methods, and conceptual advances for studying neurotransmitter receptors and other synaptic proteins. It describes a broad range of molecular, biochemical, imaging, and electrophysiological approaches for studying the biology of synapses. Specific topics include the use of proteomics to study synaptic protein complexes, the development of phosphorylation state specific antibodies, post-genomic tools applied to the study of synapses and RNA interference in neurons. In addition, several chapters focus on methods for gene and protein delivery into neuronal tissue. The use of biochemical, electrophysiological and optical tagging techniques to study the movement and membrane trafficking of neurotransmitter receptors in the membrane of live nerve cells are also discussed. To complement these approaches, the application of approaches for achieving long-term alterations in the genetic complement of neurons in vivo using viral vectors or homologous recombination of ES cells are also described.

Cell Type Diversity in the Nervous System From Genes to Function

Cell Type Diversity in the Nervous System  From Genes to Function
Author: Miao He,Giordano Lippi,Jiangteng Lu
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-02-04
ISBN: 2889743365
Category: Science
Language: EN, FR, DE, ES & NL

Cell Type Diversity in the Nervous System From Genes to Function Book Excerpt:

Neurobehavioral Plasticity

Neurobehavioral Plasticity
Author: Norman E. Spear,Linda P. Spear,Michael L. Woodruff
Publsiher: Psychology Press
Total Pages: 490
Release: 2013-06-17
ISBN: 1134780850
Category: Psychology
Language: EN, FR, DE, ES & NL

Neurobehavioral Plasticity Book Excerpt:

This book describes a unique combination of research programs based on a striking variety of hypotheses and procedures directed toward understanding the sources and consequences of neurobehavioral plasticity. This remarkable attribute of the nervous system -- to be pliable and capable of being shaped or formed by natural or artificial sources toward adaptation or maladaptation -- is considered in terms of the neurochemical forces and neuroanatomical structure that has been found to be pivotal for this function. The impetus for this volume was a symposium held to honor Robert L. Isaacson for his scientific and pedagogical achievements as well as his contributions to behavioral neuroscience. Corresponding to his three major research interests, the book is divided into three sections as follows: * the first explores the relationship between the limbic system and behavior, with an emphasis on learning and memory; * the second considers -- through a wide range of approaches -- issues of plasticity in behavior and brain; and * the third deals with neural and chemical determinants of normal and abnormal behavior. This volume is not only a fitting tribute to Isaacson, but also an unusual collection of new evidence, procedures, and theories destined to have significant influence on behavioral neuroscience.

Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases

Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases
Author: Tuan Leng Tay,Giuseppe Locatelli,Gabriela Constantin,V. Wee Yong
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-05-03
ISBN: 2889760707
Category: Medical
Language: EN, FR, DE, ES & NL

Understanding the Roles of Glia and Circulating Leukocytes in Neurodegenerative Diseases Book Excerpt:

Development Maturation and Senescence of Neuroendocrine Systems

Development  Maturation  and Senescence of Neuroendocrine Systems
Author: Colin Scanes
Publsiher: Elsevier
Total Pages: 444
Release: 2012-12-02
ISBN: 0323150128
Category: Science
Language: EN, FR, DE, ES & NL

Development Maturation and Senescence of Neuroendocrine Systems Book Excerpt:

Development, Maturation, and Senescence of Neuroendocrine Systems: A Comparative Approach discusses the various phases of the aging continuum of neuroendocrine systems. This book explores the fundamental and physiological component of animals, which is an essential contributor to senescence. Organized into three parts encompassing 21 chapters, this volume starts with a discussion of the concept of neurosecretory neuron that was introduced by Ernst Scharrer in 1928. This book discusses the challenges in the study of the development of the neuroendocrine system in insects, with a focus on Lepidoptera. Other chapters consider the neuroendocrine mechanisms that control the physiological processes in crustaceans. The reader is then introduced to the major neurohemal structures in crustaceans, including the sinus gland, the pericardial organs, and the post-commissural organs. The final chapter discusses the two brain systems that show impact of endogenous steroids that account for subsets of senescent changes. This book is a valuable resource for neurobiologists, molecular biologists, and immunologists.

Cellular Migration and Formation of Neuronal Connections

Cellular Migration and Formation of Neuronal Connections
Author: Anonim
Publsiher: Academic Press
Total Pages: 1080
Release: 2013-05-06
ISBN: 0123973473
Category: Science
Language: EN, FR, DE, ES & NL

Cellular Migration and Formation of Neuronal Connections Book Excerpt:

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.

Synaptic Assembly and Neural Circuit Development

Synaptic Assembly and Neural Circuit Development
Author: Jaewon Ko,Chen Zhang
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2018-11-02
ISBN: 2889456307
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Synaptic Assembly and Neural Circuit Development Book Excerpt:

What we learn and when we learn it sensitive periods in development

What we learn and when we learn it  sensitive periods in development
Author: Etienne De Villers-Sidani,Virginia Penhune
Publsiher: Frontiers E-books
Total Pages: 135
Release: 2014-11-21
ISBN: 2889193276
Category: Electronic Book
Language: EN, FR, DE, ES & NL

What we learn and when we learn it sensitive periods in development Book Excerpt:

The impact of training or experience is not the same at all points in development. Children who receive music lessons, or learn a second language before age 7-8 are more proficient as adults. Early exposure to drugs or trauma makes people more likely to become addicted or depressed later life. Rat pups exposed to specific frequencies from 9-13 days post-partum show expanded cortical representations of these frequencies. Young birds must hear and copy their native song within 1-2 months of birth or they may never learn it at all. These are examples of sensitive periods: developmental windows where maturation and specific experience interact to produce differential long-term effects on the brain and behavior. While still controversial, evidence for the existence of sensitive periods has grown, as has our understanding of the underlying mechanisms of brain plasticity. Behavioral evidence from studies of language, psychopathology or vision in humans has been complemented by evidence elucidating molecular, gene and hormonal mechanisms in animals. It has been proposed that sensitive periods can be both opened and closed by specific experience, and that there are multiple, overlapping sensitive periods that occur through-out development as functions come on line. It is also likely that experience-dependent behavioral or brain plasticity accrued during one sensitive period can serve as a scaffold on which later experience and plasticity can build. Based on current knowledge, there are a number of broad questions and challenges to be addressed in this domain, these include: generating new information about the neurobiological mediators of structural and functional changes; proposing models of brain development that will better predict when sensitive periods should occur and what functions are implicated; investigation of the interaction between experience during a sensitive period and pre-existing individual differences; and the relationship between experience during a sensitive period and on-going experience. The goal of this Research Topic is to bring together scientists in different fields whose work addresses these issues, including animal and human developmental neuroscience, language and cognitive development, education, developmental psychopathology and sensory neuroscience.

Latest Advances on Excitatory Synapse Biology

Latest Advances on Excitatory Synapse Biology
Author: Kimberly M. Huber,Pierre Paoletti,P. Jesper Sjöström
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-11-25
ISBN: 2889716813
Category: Science
Language: EN, FR, DE, ES & NL

Latest Advances on Excitatory Synapse Biology Book Excerpt:

Maturation of the Nervous System

Maturation of the Nervous System
Author: Anonim
Publsiher: Elsevier
Total Pages: 422
Release: 2011-09-22
ISBN: 0080861733
Category: Medical
Language: EN, FR, DE, ES & NL

Maturation of the Nervous System Book Excerpt:

Maturation of the Nervous System

Principles of Neurobiology

Principles of Neurobiology
Author: Liqun Luo
Publsiher: Garland Science
Total Pages: 734
Release: 2020-09-05
ISBN: 1000096807
Category: Science
Language: EN, FR, DE, ES & NL

Principles of Neurobiology Book Excerpt:

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.

Development and Plasticity in Sensory Thalamus and Cortex

Development and Plasticity in Sensory Thalamus and Cortex
Author: Reha Erzurumlu,William Guido,Zoltan Molnar
Publsiher: Springer Science & Business Media
Total Pages: 322
Release: 2006-10-28
ISBN: 0387386076
Category: Medical
Language: EN, FR, DE, ES & NL

Development and Plasticity in Sensory Thalamus and Cortex Book Excerpt:

This volume provides an update on the multitude of technical and experimental approaches in understanding the development and plasticity of the mammalian sensory thalamus and neocortex. The focus is on visual and somatosensory thalamus and neocortex in rodents and carnivores, and functional imaging studies in developing and aging human neocortex. It further provides a synthetic theoretical framework for future studies.

Study of a Kinesin Adaptor in Axonal Transport and Synapse Formation

Study of a Kinesin Adaptor in Axonal Transport and Synapse Formation
Author: Tahere Kalantary Dehaghi
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Study of a Kinesin Adaptor in Axonal Transport and Synapse Formation Book Excerpt:

To form a synaptic terminal, various components have to be targeted to specific sites in the axon. Presynaptic proteins are synthesized in the cell soma, packaged in vesicular cargos and transported by the motor complexes traveling along microtubules. During synapse development and maturation, the intracellular transport of proteins is highly regulated by mechanisms governing the interactions and movement of motor proteins. Additional specificity and regulation is provided by interaction of motor proteins with their cargos through adaptor and scaffolding proteins. Previous studies have show...

The Development of Synapses

The Development of Synapses
Author: Uriel Sandbank,J. J. Bubis
Publsiher: Unknown
Total Pages: 39
Release: 1974
ISBN: 1928374650XXX
Category: Central Nervous System
Language: EN, FR, DE, ES & NL

The Development of Synapses Book Excerpt:

Human Epigenomics

Human Epigenomics
Author: Carsten Carlberg,Ferdinand Molnár
Publsiher: Springer
Total Pages: 223
Release: 2018-02-01
ISBN: 9811076146
Category: Medical
Language: EN, FR, DE, ES & NL

Human Epigenomics Book Excerpt:

The term epigenetics describes regulatory and information storing mechanisms of specific genes that do not involve any change of their DNA sequence. Epigenetics is closely related to the extensively folded state, in which the genome is packaged, known as chromatin. New genomic tools nowadays allow the genome-wide assessment of, for example, chromatin states and DNA modifications, and led to the discovery of unexpected new epigenetic principles, such as epigenomic memory. This was the start of the field of epigenomics, the relation of which to human health and disease is discussed in this textbook. This book aims to summarize, in a condensed form, the role of epigenomics in defining chromatin states that are representative of active genes (euchromatin) and repressed genes (heterochromatin). Moreover, this book discusses the principles of gene regulation, chromatin stability, genomic imprinting and the reversibility of DNA methylation and histone modifications. This information should enable a better understanding of cell type identities and will provide new directions for studies of, for example, cellular reprograming, the response of chromatin to environmental signals and epigenetic therapies that can improve or restore human health. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. The content of the book is based on the lecture course “Molecular Medicine and Genetics” that is given by one of us (C. Carlberg) in different forms since 2002 at the University of Eastern Finland in Kuopio. Thematically, this book is located between our textbooks “Mechanisms of Gene Regulation” (ISBN 978-94-017-7741-4) and “Nutrigenomics” (ISBN 978-3-319-30415-1), studying of which may also be interesting to our readers. The book is sub-divided into three sections and 13 chapters. Following the Introduction (section A), section B will explain the molecular basis of epigenomics, while section C will provide examples for the impact of epigenomics in human health and disease. The lecture course is primarily designed for Master level students of biomedicine, but is also frequented by PhD students as well as by students of other bioscience disciplines. Besides its value as a textbook, Human Epigenomics will be a useful reference for individuals working in biomedicine.