Pathogenesis of Systemic Lupus Erythematosus

Pathogenesis of Systemic Lupus Erythematosus
Author: Alberta Hoi
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN: 3030851613
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Pathogenesis of Systemic Lupus Erythematosus Book Excerpt:

Advanced Handbook of Systemic Lupus Erythematosus

Advanced Handbook of Systemic Lupus Erythematosus
Author: Laurent Arnaud,Ronald van Vollenhoven
Publsiher: Springer
Total Pages: 167
Release: 2017-09-10
ISBN: 3319430351
Category: Medical
Language: EN, FR, DE, ES & NL

Advanced Handbook of Systemic Lupus Erythematosus Book Excerpt:

This book will provide an introduction to the epidemiology, etiology and pathogenesis of the condition while also exploring the classification, diagnosis, and current and emerging therapies for systemic lupus erythematosus. Systemic lupus erythematosus is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. The underlying cause of the disease is not fully known, and SLE is much more common in women than in men. It may occur at any age but most often occurs in people between 10 and 50 years of age. This is the second Adis title from Ronald F van Vollenhoven, who previously authored Biologics for the Treatment of Rheumatoid Arthritis.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author: Peter A. Miescher
Publsiher: Springer
Total Pages: 225
Release: 2011-12-27
ISBN: 9783642796241
Category: Medical
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus Book Excerpt:

During the past 50 years, systemic lupus erythematosus (SLE) has been the main subject in the field of immunopathology. Each individual discovery was followed by the discovery of a multitude of related immune phenomena. This book reflects the present status of our understanding of this protean disease. Various animal models clearly show that different gene combinations can lead to the final clinical expression of SLE, with HLA class II genes probably responsible for the targeting of the autoimmune response. Similarly, research on cytokines in SLE patients has shown that SLE is a syndrome depending on different pathways. Finally, the question of prognosis is discussed. Fortunately, with every passing decade, the prognosis for patients with SLE gets better and better.

Outcome Measures and Metrics in Systemic Lupus Erythematosus

Outcome Measures and Metrics in Systemic Lupus Erythematosus
Author: Zahi Touma
Publsiher: Springer Nature
Total Pages: 418
Release: 2021-07-22
ISBN: 3030733033
Category: Medical
Language: EN, FR, DE, ES & NL

Outcome Measures and Metrics in Systemic Lupus Erythematosus Book Excerpt:

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.

Progress in Systemic Lupus Erythematosus Research

Progress in Systemic Lupus Erythematosus Research
Author: Tomas I. Seward
Publsiher: Nova Publishers
Total Pages: 264
Release: 2007
ISBN: 9781600218613
Category: Systemic lupus erythematosus
Language: EN, FR, DE, ES & NL

Progress in Systemic Lupus Erythematosus Research Book Excerpt:

This new book is devoted to leading-edge research developments in lupus which is a condition of chronic inflammation caused by an autoimmune disease. Autoimmune diseases are illnesses that occur when the body's tissues are attacked by its own immune system. The immune system is a complex system within the body that is designed to fight infectious agents, for example, bacteria, and other foreign invaders. One of the mechanisms that the immune system uses to fight infections is the production of antibodies. Patients with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. Because the antibodies and accompanying cells of inflammation can involve tissues anywhere in the body, lupus has the potential to affect a variety of areas of the body. Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author: Josef S. Smolen,Christoph C. Zielinski
Publsiher: Springer Science & Business Media
Total Pages: 358
Release: 2012-12-06
ISBN: 3642716423
Category: Medical
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus Book Excerpt:

More than 140 years ago, lupus erythematosus (LE) was recognized as a disease entity by clinicians working in the field of dermatology, which had only recently become an independent medical discipline. Soon after cutaneous lupus was first reported, it was realized that, apart from the skin, the disease could involve other organs and thus be systemic in nature. The latter observations were first made by MORITZ KApOSI [1], whose work has attracted renewed attention re cently and who succeeded FERDINAND VON HEBRA to the chair of dermatology at the Medical Faculty in Vienna. The early description of lupus erythematosus in both its cutaneous and systemic manifes tations was thus intimately associated with Vienna and its Medical School. The next phase in the study of lupus was characterized by an in crease in knowledge of the type and extent of organ involvement. The work by OSLER [2], LIBMANN and SACKS [3], and KLEMPERER [4] best represents these advances. The increase in clinical knowledge of LE finally led to DUBOIS' famous monograph [5], which was pub lished at a time of renewed interest in SLE, elicited by the descrip tion by HARGRAVES et al. [6] of the LE-cell phenomenon. A more detailed analysis of this finding revealed that the disease was charac terized by an abnormal immune response, although its pathogenetic implications were still unclear.

Focusing on T cells for Novel Treatments of Systemic Lupus Erythematosus

Focusing on T cells for Novel Treatments of Systemic Lupus Erythematosus
Author: Masayuki Mizui,Kunihiro Ichinose,Christian Michael Hedrich,Vaishali R. Moulton
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-11-01
ISBN: 2889714179
Category: Medical
Language: EN, FR, DE, ES & NL

Focusing on T cells for Novel Treatments of Systemic Lupus Erythematosus Book Excerpt:

A Mathematical Modelling Study of the Autoimmune Disease Systemic Lupus Erythematosus SLE

A Mathematical Modelling Study of the Autoimmune Disease  Systemic Lupus Erythematosus  SLE
Author: Qi Li
Publsiher: Unknown
Total Pages: 264
Release: 1991
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

A Mathematical Modelling Study of the Autoimmune Disease Systemic Lupus Erythematosus SLE Book Excerpt:

Systemic Lupus Erythematosus New Insights for the Healthcare Professional 2012 Edition

Systemic Lupus Erythematosus  New Insights for the Healthcare Professional  2012 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 140
Release: 2012-12-10
ISBN: 1464971625
Category: Medical
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus New Insights for the Healthcare Professional 2012 Edition Book Excerpt:

Systemic Lupus Erythematosus: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Systemic Lupus Erythematosus. The editors have built Systemic Lupus Erythematosus: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Systemic Lupus Erythematosus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Systemic Lupus Erythematosus: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author: Anonim
Publsiher: Unknown
Total Pages: 32
Release: 2000
ISBN: 1928374650XXX
Category: Autoimmune diseases
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus Book Excerpt:

Discovery and Validation of Systemic Lupus Erythematosus SLE Diseases Activity Biomarkers

Discovery and Validation of Systemic Lupus Erythematosus  SLE  Diseases Activity Biomarkers
Author: Jason Wesley Bauer
Publsiher: Unknown
Total Pages: 280
Release: 2007
ISBN: 1928374650XXX
Category: Biochemical markers
Language: EN, FR, DE, ES & NL

Discovery and Validation of Systemic Lupus Erythematosus SLE Diseases Activity Biomarkers Book Excerpt:

Systemic Lupus Erythematosus SLE

Systemic Lupus Erythematosus  SLE
Author: Irvine Turner
Publsiher: Unknown
Total Pages: 90
Release: 2017
ISBN: 9781536106909
Category: HEALTH & FITNESS
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus SLE Book Excerpt:

Being diagnosed with Systemic Lupus Erythematosus (SLE) can be a severe disappointment, and life after diagnosis can be defined as an existence filled with uncertainty as to the short-and long-term impact of the disease. SLE is a chronic multi-system autoimmune disease that is persistent and recurrent and has the potential of becoming life threatening. The manifestations and severity of the disease varies between individuals. SLE can potentially influence nearly all of the body's organ systems. In this book, Chapter One reviews, Raynaud's phenomenon (RP), one of the nonspecific skin changes that occur in SLE. Chapter Two presents the debate on the causes of fatigue in SLE and factors that increase fatigue. Chapter Three reviews and illustrates the important findings of musculoskeletal diseases in SLE. Chapter Four examines SLE in young adults and reviews information about the pain, social impact, and interventions to improve functioning of these young adults.

The Clinical Management of Systemic Lupus Erythematosus

The Clinical Management of Systemic Lupus Erythematosus
Author: Peter H. Schur
Publsiher: Lippincott Williams & Wilkins
Total Pages: 281
Release: 1996
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

The Clinical Management of Systemic Lupus Erythematosus Book Excerpt:

This volume is designed to provide clinicians with practical guidance on the diagnosis and management of systemic lupus erythematosus. Revised and updated to reflect diagnostic and therapeutic advances, the book offers advice on the day-to-day care of patients with the varied manifestations of this disease.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author: Robert George Lahita
Publsiher: Churchill Livingstone
Total Pages: 1000
Release: 1987
ISBN: 1928374650XXX
Category: Aortitis
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus Book Excerpt:

Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. Four-color illustrations throughout, this book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, and newest methods of therapy of antiphospholipid syndrome are given in this newest edition of a classic reference. * Comprehensive current coverage of basic models of etiology and pathogenesis * Complete catalog of autoantibodies produced * Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system * Includes CD-ROM of images excellent for teaching purposes and downloading into presentations

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author: United States. Public Health Service
Publsiher: Unknown
Total Pages: 8
Release: 1967
ISBN: 1928374650XXX
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus Book Excerpt:

Systemic Lupus Erythematosus SLE

Systemic Lupus Erythematosus  SLE
Author: Syuichi Koarada
Publsiher: Nova Biomedical
Total Pages: 120
Release: 2013-01-01
ISBN: 9781628089905
Category: Medical
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus SLE Book Excerpt:

Systemic lupus erythematosus (SLE) is one of the prototypical systemic autoimmune diseases characterized by inflammation, immune complex deposition, and vasculitis.?Patients with SLE show various symptoms and clinical images, both constitutional and specific organ symptoms. They include the skin, joints, muscles, kidneys, lungs, nervous system, and blood vessels. Although the etiology of the disease is still unclear, genetic, hormonal, immunologic abnormalities and environmental factors complicatedly play important roles in the pathophysiology in SLE. It is evident that multiple genes show genetic susceptibility to SLE. Environmental factors of SLE and immunologic abnormalities, especially the production of a number of auto-antibody, are important features of the disease. In this book, we present recent knowledge about the prevalence, pathophysiology and prognosis of SLE. The book includes various interesting chapters: Chapter One - an illustrated overview of the prevalence and clinical symptoms of systemic lupus erythematosus; Chapter Two - the pathophysiology of systemic lupus erythematosus; Chapter Three - MBL and MBL genotypes in SLE; Chapter Four - novel biological activities of autoantibodies as the potential markers of systematic lupus erythematosus; Chapter Five - cytokines in systemic lupus erythematosus (sle) with clinical aspects and prognostics; Chapter Six - prognosis in systemic lupus erythematosus; and Chapter Seven - autoantibody-producing RP105-negative B cells in humans and a murine model of lupus erythematosus.

Stat4 and Blk But Not Pxk Are Associated with Systemic Lupus Erythematosus Sle in Hong Kong Chinese

Stat4 and Blk  But Not Pxk  Are Associated with Systemic Lupus Erythematosus  Sle  in Hong Kong Chinese
Author: Ping Ng,吳萍
Publsiher: Open Dissertation Press
Total Pages: 135
Release: 2017-01-27
ISBN: 9781374678361
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Stat4 and Blk But Not Pxk Are Associated with Systemic Lupus Erythematosus Sle in Hong Kong Chinese Book Excerpt:

This dissertation, "STAT4 and BLK, but Not PXK, Are Associated With Systemic Lupus Erythematosus (SLE) in Hong Kong Chinese" by Ping, Ng, 吳萍, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b4150852 Subjects: Systemic lupus erythematosus - China - Hong Kong - Genetic aspects

Lahita s Systemic Lupus Erythematosus

Lahita s Systemic Lupus Erythematosus
Author: Robert G. Lahita
Publsiher: Academic Press
Total Pages: 730
Release: 2021-07-23
ISBN: 0323914888
Category: Medical
Language: EN, FR, DE, ES & NL

Lahita s Systemic Lupus Erythematosus Book Excerpt:

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries. Completely updated, revised, and expanded with the most comprehensive and accessible reference on SLE for clinicians and scientists Full-color presentation throughout the book Provides the latest information available on diagnosis and treatment Incorporates an international panel of authors who are experts in their fields, with an emphasis on young, cutting-edge scientists and physicians

Systemic Lupus Erythematosus An Issue of Rheumatic Disease Clinics

Systemic Lupus Erythematosus  An Issue of Rheumatic Disease Clinics
Author: Ellen M. Ginzler
Publsiher: Elsevier Health Sciences
Total Pages: 185
Release: 2014-08-19
ISBN: 032332388X
Category: Medical
Language: EN, FR, DE, ES & NL

Systemic Lupus Erythematosus An Issue of Rheumatic Disease Clinics Book Excerpt:

In only the last four years, there have been dramatic changes in the understanding of the immunology, genetic/epigenetic associations, and identification of new targets for therapy in Systemic Lupus Erythematosus. The editors have enlisted a superb group of authors to present articles detailing cutting-edge advances in these areas.

Pathology of Systemic Lupus Erythematosus

Pathology of Systemic Lupus Erythematosus
Author: Tatiana T. Antonovych
Publsiher: American Registry of Pathology
Total Pages: 175
Release: 1995
ISBN: 1928374650XXX
Category: Systemic lupus erythematosus
Language: EN, FR, DE, ES & NL

Pathology of Systemic Lupus Erythematosus Book Excerpt: