Tertiary Amines en Route to Natural Products

   Tertiary Amines en Route to Natural Products
Author: Abdul Hameed,Mariya Al-Rashida,Muhammad Raza Shah
Publsiher: Elsevier
Total Pages: 240
Release: 2021-01-14
ISBN: 0128233680
Category: Science
Language: EN, FR, DE, ES & NL

Tertiary Amines en Route to Natural Products Book Excerpt:

a-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the a,a-disubstituted a-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, a-amino acids based natural products, a amino acid based natural products and Tetrodotoxin. This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis. Outlines synthetic strategies for natural products bearing a-tertiary amines and a,a-disubstituted a-amino acid motif Describes multistep synthetic routes that highlight key steps Covers asymmetric and diastereoselective synthetic approaches towards targeted natural products Illustrates multistep synthetic routes related to -amino acids based natural products and -amino acids based natural products

Tertiary Amines en Route to Natural Products

  Tertiary Amines en Route to Natural Products
Author: Abdul Hameed,Mariya Al-Rashida,Muhammad Raza Shah
Publsiher: Elsevier
Total Pages: 240
Release: 2021-02-09
ISBN: 012822262X
Category: Science
Language: EN, FR, DE, ES & NL

Tertiary Amines en Route to Natural Products Book Excerpt:

?-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the ?,?-disubstituted ?-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, ?-amino acids based natural products, ? amino acid based natural products and Tetrodotoxin. This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis. Outlines synthetic strategies for natural products bearing ?-tertiary amines and ?,?-disubstituted ?-amino acid motif Describes multistep synthetic routes that highlight key steps Covers asymmetric and diastereoselective synthetic approaches towards targeted natural products Illustrates multistep synthetic routes related to -amino acids based natural products and -amino acids based natural products

Alpha Olefins Applications Handbook

Alpha Olefins Applications Handbook
Author: George Lappin
Publsiher: CRC Press
Total Pages: 480
Release: 2014-02-06
ISBN: 1482254255
Category: Science
Language: EN, FR, DE, ES & NL

Alpha Olefins Applications Handbook Book Excerpt:

This book discusses the applications of higher linear alpha olefins containing 4 to 30 carbon atoms, describes current commercial uses of alpha olefins, and indicates potential new uses. It also documents methods of production and provides physical property and general property data on the olefins.

Handbook of Commercial Catalysts

Handbook of Commercial Catalysts
Author: Howard F. Rase
Publsiher: CRC Press
Total Pages: 520
Release: 2016-04-05
ISBN: 1482275368
Category: Science
Language: EN, FR, DE, ES & NL

Handbook of Commercial Catalysts Book Excerpt:

Despite the advances in understanding the phenomena that occur on a catalyst surface, much of the successful catalyst development and use continues to be half science and half art. The art resides in the practical knowledge of experts in the development and use of commercial catalysts-it comes with experience. Now the background needed to nurture t

Contamination Control in the Natural Gas Industry

Contamination Control in the Natural Gas Industry
Author: Thomas H. Wines,Saeid Mokhatab
Publsiher: Gulf Professional Publishing
Total Pages: 412
Release: 2021-11-25
ISBN: 0128169877
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Contamination Control in the Natural Gas Industry Book Excerpt:

Contamination Control in the Natural Gas Industry delivers the separation fundamentals and technology applications utilized by natural gas producers and processors. This reference covers principles and practices for better design and operation of a wide range of media, filters and systems to remove contaminants from liquids and gases, enabling gas industry professionals to fulfill diverse fluid purification requirements. Packed to cover practical technologies, diagnostics and troubleshooting methods, this book provides gas engineers and technologists with a critical first-ever reference geared to contamination control. Covers contamination control methods and equipment specific to the natural gas industry Includes guidelines on fundamentals and real-world technologies used today Gives engineers better design and operation with rating methods, standards and case histories

Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products

Fortschritte der Chemie organischer Naturstoffe   Progress in the Chemistry of Organic Natural Products
Author: Anonim
Publsiher: Springer Science & Business Media
Total Pages: 211
Release: 2012-12-06
ISBN: 370916351X
Category: Science
Language: EN, FR, DE, ES & NL

Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products Book Excerpt:

In order to make further progress in elucidating the mechanism of NOS catalysis it will be essential to throw light on the interaction between the enzyme and its substrate. An understanding of the catalytic site will also assist the development of therapeutically important NOS inhibitors. In particular. it will be useful to uncover any differences that exist between the substrate binding sites of the three NOS isozymes which might be exploited for the development of isoform selective NOS inhibitors. A comparison of NOS to other Arg-binding proteins has shown no significant sequence homology (159). Moreover, the lack of a 3D structure and absence of significant sequence homology between the NOS oxygenase domain and known cytochromes P450 has made it difficult to identify residues and construct a model of the distal heme pocket responsible for substrate binding. However, a number of groups are currently working towards crystallisation of the separate NOS reductase and oxygenase domains of the three isoforms for X-ray diffraction studies; the first X-ray structure is likely to be forthcoming within a matter of months. * The results of these studies are expected to resolve many of the uncertainties surrounding the structure of the NOS catalytic site. Preliminary X-ray diffraction analysis of CPR from rat liver has already been reported by MASTERS et al. (524) and the future emergence of a detailed structure for this protein should throw light on the structure and function of the NOS reductase domain.

Recent Advances in Applications of Name Reactions in Multicomponent Reactions

Recent Advances in Applications of Name Reactions in Multicomponent Reactions
Author: Majid M. Heravi,Vahideh Zadsirjan
Publsiher: Elsevier
Total Pages: 438
Release: 2020-05-29
ISBN: 0128196955
Category: Science
Language: EN, FR, DE, ES & NL

Recent Advances in Applications of Name Reactions in Multicomponent Reactions Book Excerpt:

Recent Advances in Applications of Name Reactions in Multicomponent Reactions is an ideal reference for researchers and postgraduate students studying organic chemistry, as well as synthetic organic chemists working on the development of novel methodologies for the synthesis of various heterocyclic systems, especially drug design and discovery, in both academia and industry. The book reviews recent applications of name reactions in multicomponents for the synthesis of heterocycles and examines recent advances in applications of significant name reactions, such as Ugi and Passirini, Click, Knoevenagel, Michael, Diels-Alder, Aldol, Mannich, Heck, Huisgen, and Suzuki in MCRs. These reactions can be used in the synthesis of a wide variety of novel heterocycles with different sizes and heteroatoms, as well as in the total synthesis of natural products in order to decrease the number of synthetic steps. Since chiral inductions are necessary for most of these sequential name reactions, their asymmetric catalyzed reactions are also described. Includes the synthesis of many heterocycles, which is ideal for synthetic organic chemists engaged in the synthesis of heterocyclic systems Covers the recent advances of asymmetric synthesis of a wide range of heterocycles in satisfactory enantioselectivities (ees) or distereoselectivities (des) Reviews the synthesis of a wide variety of interesting heterocycles by using a combination of different and versatile name reactions via MCRs

Handbook of Surfactants

Handbook of Surfactants
Author: M.R. Porter
Publsiher: Springer
Total Pages: 227
Release: 2013-04-17
ISBN: 1475712936
Category: Science
Language: EN, FR, DE, ES & NL

Handbook of Surfactants Book Excerpt:

The worldwide consumption of surfactants now exceeds several million tonnes per annum. Six ofthe major types represent approximately 80% ofthe volume consumed, whereas the remaining 20% is made up of approximately 40 different chemical types. Commercially produced surface active agents are not pure chemicals, and within each chemical type there can be tremendous variation. Technical staff who are not familiar with surfactants are frequently bewildered by the enormous variety of different products on the market and the vast body of literature which exists on the composition and properties of surfactants. The selection of the best surfactant for any given use therefore becomes a major problem. This volume arose from the clear need to have available a simple reference book summarising the different types of surfactants on the market and their properties. The concept and structure of the book evolved from early attempts to define chemical structure/property relationships of all the different types of surfactants commercially available, into a simple handbook providing essential background information for the surfactant user. It is realised that most users will be developing their own data bank of structure/end use property relationships and they will therefore be the experts on end use.

Proceedings of the World Conference on Palm and Coconut Oils for the 21st Century

Proceedings of the World Conference on Palm and Coconut Oils for the 21st Century
Author: Edward George Perkins,Arno Cahn
Publsiher: The American Oil Chemists Society
Total Pages: 158
Release: 1999
ISBN: 9780935315998
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Proceedings of the World Conference on Palm and Coconut Oils for the 21st Century Book Excerpt:

This book covers a wide range of food and oleochemical applications of palm and coconut oils. The presentations were part of the World Conference on Palm and Coconut Oils for the 21st Century held in Bali and reflect the changes in the oleochemical industry during the past decade.

Synthesis of Pesticides Chemical Structure and Biological Activity Natural Products with Biological Activity

Synthesis of Pesticides Chemical Structure and Biological Activity Natural Products with Biological Activity
Author: H. Geissbühler,G. T. Brooks,P. C. Kearney
Publsiher: Elsevier
Total Pages: 348
Release: 2013-10-22
ISBN: 1483278514
Category: Technology & Engineering
Language: EN, FR, DE, ES & NL

Synthesis of Pesticides Chemical Structure and Biological Activity Natural Products with Biological Activity Book Excerpt:

Advances in Pesticide Science, Part 2: Synthesis of Pesticides, Chemical Structure and Biological Activity, Natural Products with Biological Activity is a collection of papers presented at the Fourth International Congress of Pesticide Chemistry, held in Zurich, Switzerland on July 24-28, 1978. This book is composed of forty eight chapters, and begins with the synthesis of pesticides. The succeeding chapters deal with heterocyclic synthesis by rearrangement, synthesis and transformations of nitrogen and sulphurcontaining bicyclic heterocyclic systems. These topics are followed by discussions on synthesis of bmc-analogous n-heterocycles from 1,2-, 1,3-, 1,4-, and 1,5- diamines. Other chapters describe the synthesis and herbicidal activity of 4-acylpyrazole derivatives, the synthesis and properties of plant growth regulators, the carboxyphenyl derivatives of five and six membered heterocycles and potential phosphorus-containing intermediates for the synthesis of pesticides. The final chapters consider the influence of antagonistic fungi on the spore-formation of rust fungi. This book will prove useful to agriculturists and organic chemists.

Marine Natural Products

Marine Natural Products
Author: Hiromasa Kiyota
Publsiher: Springer Nature
Total Pages: 517
Release: 2021-09-02
ISBN: 9811646376
Category: Science
Language: EN, FR, DE, ES & NL

Marine Natural Products Book Excerpt:

This book is a compilation of the latest achievements of leading researchers in marine natural products with extremely diverse structures and biological activities. It presents discussions of isolation, structure elucidation, biosynthesis, total synthesis, and biochemical properties of the compounds with characteristic structures such as macrolides, cyclic depsipeptides, alkaloids, and water-soluble heterocyclic low-molecular-weight compounds, from sponges, bacteria, cyanobacteria, flagellates, and other such organisms. The book especially focuses on heterocyclic natural products as a title in the book series, Topics in Heterocyclic Chemistry.

Absorption and Utilization of Amino Acids

Absorption and Utilization of Amino Acids
Author: Mendel Friedman
Publsiher: CRC Press
Total Pages: 321
Release: 2018-04-19
ISBN: 1351077899
Category: Medical
Language: EN, FR, DE, ES & NL

Absorption and Utilization of Amino Acids Book Excerpt:

Containing 45 papers written by outstanding international authors from 14 countries, this three-volume compendium brings together the elements needed to understand the factors which influence the utilization of amino acids. The wide-ranging topics include descriptions of metabolic pathways and mechanisms of the biological utilization of amino acids, as well as factors that influence amino acid bioavailability in enteral and parenteral nutrition. The use of amino acids to improve the quality and safety of the diet is presented. Also discussed are amino acid precursors of biogenic amines and the role of amino acids in atherosclerosis, cancer, and immunity. Scientists from many disciplines will benefit from this broad overview.

Low Molecular Weight Sulphur Containing Natural Products

Low Molecular Weight Sulphur Containing Natural Products
Author: J. Wróbel
Publsiher: Elsevier
Total Pages: 80
Release: 2013-10-22
ISBN: 1483154416
Category: Science
Language: EN, FR, DE, ES & NL

Low Molecular Weight Sulphur Containing Natural Products Book Excerpt:

Low Molecular Weight Sulphur Containing Natural Products contains plenary lectures presented at the International Symposium on Low Molecular Weight Sulphur Containing Natural Products held at Jablonna, Warsaw on July 12-16, 1976. This book contains six papers separated as chapters. Topics include low molecular weight sulfur-containing compounds in nature; oxidation of some biologically active and related sulfur containing compounds; and the α-mercapto-α-amino acids and dehydro amino acids. This text also explores properties of sulfur containing nuphar alkaloids; new aspects of the chemistry of biotin and of some analogs; and the glucosinolates.

Methodologies in Amine Synthesis

Methodologies in Amine Synthesis
Author: Alfredo Ricci,Luca Bernardi
Publsiher: John Wiley & Sons
Total Pages: 480
Release: 2021-01-20
ISBN: 3527826173
Category: Science
Language: EN, FR, DE, ES & NL

Methodologies in Amine Synthesis Book Excerpt:

Provides a unique overview of efficient synthetic routes to one of the most important compound classes in organic and pharmaceutical chemistry! Amines are among the most important compounds in organic chemistry due to their wide occurrence in natural products, drugs, crop protection compounds, and advanced materials. For example, the majority of drugs are amines or contain functional groups derived from amines. Powerful and efficient methods for the introduction of the amino group are therefore of great importance to synthetic chemists in academia and industry. Methodologies in Amine Synthesis: Challenges and Applications presents powerful and state-of-the-art methods for the efficient preparation of amines. It summarizes recent advances in the electrophilic amination reaction, hydroamination, C?H amination as well as newly developed photocatalytic approaches. It further describes organocatalytic and enzymatic routes to the generation of amines under mild and environmentally friendly conditions. In addition, it highlights the relevance of the amino function in bioactive molecules, drugs, and in the engineering of smart materials. Finally, the application of palladium-catalyzed aromatic amination in industrial context is critically discussed. Only up-to-date and comprehensive book on the preparation of amines ? one of the most frequently occurring compound classes found in natural products, bioactive molecules, and advanced materials. Presents efficient and useful synthetic methods, highlights opportunities / challenges as well as applications in pharmaceutical chemistry and materials science. Chapters are compiled by well-known experts in the field. One of them edited the previous books Modern Amination Methods (2001) and Amino Group Chemistry (2007). The book Methodologies in Amine Synthesis: Challenges and Applications is a musthave for chemists in academia and industry working in the field of organic synthesis and catalysis, natural product chemistry, drug synthesis and pharmaceutical chemistry, as well as materials science.

Surfactants from Renewable Resources

Surfactants from Renewable Resources
Author: Mikael Kjellin,Ingegärd Johansson
Publsiher: John Wiley & Sons
Total Pages: 336
Release: 2010-01-26
ISBN: 9780470686614
Category: Science
Language: EN, FR, DE, ES & NL

Surfactants from Renewable Resources Book Excerpt:

Most modern surfactants are readily biodegradable and exhibit low toxicity in the aquatic environment, the two criteria for green surfactants. However the majority are synthesised from petroleum, so over the past decade the detergent industry has turned its attention to developing greener routes to create these surfactants via renewable building blocks. Surfactants from Renewable Resources presents the latest research and commercial applications in the emerging field of sustainable surfactant chemistry, with emphasis on production technology, surface chemical properties, biodegradability, ecotoxicity, market trends, economic viability and life-cycle analysis. Reviewing traditional sources for renewable surfactants as well as recent advances, this text focuses on techniques with potential for large scale application. Topics covered include: Renewable hydrophobes from natural fatty acids and forest industry by-products Renewable hydrophiles from carbohydrates, amino acids and lactic acid New ways of making renewable building blocks; ethylene from renewable resources and complex mixtures from waste biomass Biosurfactants Surface active polymers This book is a valuable resource for industrial researchers in companies that produce and use surfactants, as well as academic researchers in surface and polymer chemistry, sustainable chemistry and chemical engineering.

Organic Synthesis Using Biocatalysis

Organic Synthesis Using Biocatalysis
Author: Animesh Goswami,Jon D. Stewart
Publsiher: Academic Press
Total Pages: 438
Release: 2015-09-06
ISBN: 012411542X
Category: Science
Language: EN, FR, DE, ES & NL

Organic Synthesis Using Biocatalysis Book Excerpt:

Organic Synthesis Using Biocatalysis provides a concise background on the application of biocatalysis for the synthesis of organic compounds, including the important biocatalytic reactions and application of biocatalysis for the synthesis of organic compounds in pharmaceutical and non-pharmaceutical areas. The book provides recipes for carrying out various biocatalytic reactions, helping both newcomers and non-experts use these methodologies. It is written by experts in their fields, and provides both a current status and future prospects of biocatalysis in the synthesis of organic molecules. Provides a concise background of the application of biocatalysis for the synthesis of organic compounds Expert contributors present recipes for carrying out biocatalytic reactions, including subject worthy discussions on biocatalysis in organic synthesis, biocatalysis for selective organic transformation, enzymes as catalysis for organic synthesis, biocatalysis in Industry, including pharmaceuticals, and more Contains detailed, separate chapters that describe the application of biocatalysis

Evaluation of Environmental Contaminants and Natural Products A Human Health Perspective

Evaluation of Environmental Contaminants and Natural Products  A Human Health Perspective
Author: Ashita Sharma,Manish Kumar,Satwinderjeet Kaur ,Avinash Kaur Nagpal
Publsiher: Bentham Science Publishers
Total Pages: 296
Release: 2019-06-10
ISBN: 981141095X
Category: Science
Language: EN, FR, DE, ES & NL

Evaluation of Environmental Contaminants and Natural Products A Human Health Perspective Book Excerpt:

Unbridled urbanization and development of natural land resources has led to the degradation of our surrounding environment. The air that we breathe, the water we drink and the food we eat is at risk of being contaminated with a plethora of chemical pollutants, some of them being potentially carcinogenic. This presents a challenge to human health. This book attempts to address this challenge in two parts which represent two different approaches. The first part of the book summarizes the alarming effects of environmental contaminants. Various studies depicting the direct relationship of environmental contaminants with cancer incidence have been referenced. Scientific studies have established an inverse relation between cancer and ingestion of dietary phytoconstituents (phytochemicals) in the form of fruits, vegetables and botanical herbs. Plant products as dietary supplements can suppress contaminant toxicity by regulating the resulting reactive species and also by assisting their bodily excretion through Phase 1 and Phase 2 enzyme metabolism. The second part of the book, shifts focus to phytoconstituents which, if included in diet, can prevent the harmful effects of pollutants. The text references numerous studies showing the anti-mutagenic, anti-genotoxic and anti-carcinogenic potential of many plant products. The combination of information about contemporary issues of carcinogenic contaminants in the environment coupled with the references to relevant studies in this handbook will enlighten readers studying courses in environmental chemistry, toxicology, botany, and ecology about environmental toxins and help them understand specific dietary measures known to reduce the toxic impact. Researchers in the field of nutrition can also benefit from the information provided.

Ni and Fe Based Cross Coupling Reactions

Ni  and Fe Based Cross Coupling Reactions
Author: Arkaitz Correa
Publsiher: Springer
Total Pages: 338
Release: 2016-11-26
ISBN: 3319497847
Category: Science
Language: EN, FR, DE, ES & NL

Ni and Fe Based Cross Coupling Reactions Book Excerpt:

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Progress in the Chemistry of Organic Natural Products Fortschritte der Chemie organischer Naturstoffe

Progress in the Chemistry of Organic Natural Products   Fortschritte der Chemie organischer Naturstoffe
Author: M. Glasenapp-Breiling,P. G. Jagtap,D. G. I. Kingston,F.-P. Montforts,L. Samala,H. Yuan
Publsiher: Springer Science & Business Media
Total Pages: 253
Release: 2012-12-06
ISBN: 3709161606
Category: Science
Language: EN, FR, DE, ES & NL

Progress in the Chemistry of Organic Natural Products Fortschritte der Chemie organischer Naturstoffe Book Excerpt:

The first contribution of this book gives an overview on naturally occuring cycling tetrapyrroles. The article describes the four classic tetrapyrrolic structures with their porphyrin, chlorin, bacteriochlorin and corrin skeletons and also novel, interesting structures with unusual biological activities. This review mainly focuses on the occurrence, structure and biological function as well as biosynthesis and aspects of synthesis. The second article deals with the anticancer compound taxol and its semisynthetic analog docetaxel (Taxotere). Taxol was originally isolated in the late 1960 ́s on the basis of its cytotoxity and antileukemic activity, its structure was published in 1971 in a paper that has been cited 1000 times since this publication. The review focuses primarily on the interesting and novel chemistry of taxol that has been discovered over the last eight years.

Ullmann s Fine Chemicals

Ullmann s Fine Chemicals
Author: Wiley-VCH
Publsiher: John Wiley & Sons
Total Pages: 1360
Release: 2014-01-07
ISBN: 3527683593
Category: Science
Language: EN, FR, DE, ES & NL

Ullmann s Fine Chemicals Book Excerpt:

A compilation of 76 articles from the ULLMANN's Encyclopedia of Industrial Chemistry, this three-volume handbook contains a wealth of information on the production and industrial use of more than 2,000 of the most important fine chemicals, from "Alcohols" to "Urea Derivatives". Chemical and physical characteristics, production processes and production figures, main uses, toxicology and safety information are all found here in one single resource.