The Collagen Superfamily and Collagenopathies

The Collagen Superfamily and Collagenopathies
Author: Florence Ruggiero
Publsiher: Springer Nature
Total Pages: 338
Release: 2021-05-15
ISBN: 3030675920
Category: Science
Language: EN, FR, DE, ES & NL

The Collagen Superfamily and Collagenopathies Book Excerpt:

This book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling events and serve critical regulatory roles in various cell functions during embryonic development and adult homeostasis. Furthermore, collagens are associated with a broad spectrum of heritability-related diseases known as “collagenopathies” that affect a multitude of organs and tissues including sensorial organs. The book is a useful introduction to the field for junior scientists, interested in extracellular matrix research. It is also an interesting read for advanced scientists and clinicians working on collagens and collagenopathies, giving them a broader view of the field beyond their area of specialization.

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 1516
Release: 1994
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Excerpt:

Rheumatology E Book

Rheumatology E Book
Author: Marc C. Hochberg,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman,Ellen M Gravallese,Desiree van der Heijde
Publsiher: Elsevier Health Sciences
Total Pages: 2123
Release: 2022-07-29
ISBN: 0702081345
Category: Medical
Language: EN, FR, DE, ES & NL

Rheumatology E Book Book Excerpt:

Covering both the scientific basis of rheumatology and practical, clinical information for rheumatologists and trainees, Rheumatology, 8th Edition, remains a leading text in this fast-changing field. Dr. Marc Hochberg and his team of worldwide editors and authors keep you abreast of recent advances in the field— all in a user-friendly, accessible manner. Fully updated from cover to cover, this two-volume text is designed to meet the needs of all practicing and academic rheumatologists as well as arthritis-related health care professionals and scientists interested in rheumatic and musculoskeletal diseases. Covers the epidemiology, pathogenesis, clinical manifestations, therapeutic approach, and management of all major as well as rarely encountered rheumatic and musculoskeletal diseases. Discusses clinical examination, imaging principles, differential diagnosis, established and novel therapies, perioperative evaluation, pain management, basic science, and genetics of rheumatic and musculoskeletal diseases. Uses a consistent, logical, reader-friendly format with templated chapters, concise text, and large-scale, state-of-the-art illustrations for efficient visual reference. Contains new chapters covering pre-clinical disease and how to address these patients, common comorbidities in rheumatoid arthritis; emerging therapies for systemic sclerosis; immune mediated complications of checkpoint inhibitors; the epidemiology of COVID-19 and rheumatic and musculoskeletal diseases, emerging treatments for osteoarthritis, and big data analytics. Provides updates to key topics such as systems biology and its impact on our understanding of the pathogenesis of rheumatic and musculoskeletal diseases, the microbiome in rheumatic musculoskeletal diseases, how to manage chronic pain in the patient with a rheumatic disease, drugs and reproductive health, and emerging therapies for patients with RA, SLE, spondyloarthritis, inflammatory muscle disease, and vasculitis. Shares the knowledge and expertise of numerous new contributing authors, as well as new co-editor Dr. Désirée van der Heijde, who is an expert in psoriatic arthritis, spondyloarthritis, imaging, and clinical epidemiology. Provides access to concise videos depicting the use of ultrasound for diagnosis and treatment.

Pediatric Orthopaedic Secrets

Pediatric Orthopaedic Secrets
Author: Lynn T. Staheli
Publsiher: Unknown
Total Pages: 487
Release: 2003
ISBN: 1928374650XXX
Category: Medical
Language: EN, FR, DE, ES & NL

Pediatric Orthopaedic Secrets Book Excerpt:

The most authoritative experts in the US and Canada have put together 100 completely updated chapters in this second edition of Pediatric Orthopaedic Secrets, covering every aspect of orthopaedic disorders in children. Pediatricians, orthopaedists, and internists will find this the perfect book for clinical use. Covered are evaluation, diagnosis, management, authoritative information from the authors' experience, pearls and tricks of the trade, and care of the whole child. Highly successful volume in first edition Concise answers that include the author's pearls, tips, memory aids Bulleted lists, tables, and illustrations for quick review Chapters written by experts their fields All the most important need-to-know questions and answers in the proven format of the highly acclaimed Secrets Series Thorough, highly detailed index