The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health

The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health
Author: Rodney A. Samaan,Christopher Samaan
Publsiher: Academic Press
Total Pages: 308
Release: 2021-08-16
ISBN: 9780128174326
Category: Science
Language: EN, FR, DE, ES & NL

The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health Book Excerpt:

The Preclinical and Clinical Effects of Cannabis and Cannabinoids on Cardiovascular Health is a comprehensive investigation into the cardiovascular health effects of marijuana use. As the prevalence of cannabis use increases both recreationally and clinically, a shroud of misinformation exists in academia, the public, and clinical realms. Further, since different studies show contradictory results it is hard to determine the exact benefits for cannabis use. This book will focus on a specific set of cardiovascular diseases plaguing the current population and the effects of cannabis will be addressed from numerous viewpoints including human physiological and clinical disease outcomes to issues in public health. By gathering this information in a way that addresses numerous viewpoints the book serves as a comprehensive reference and clinical guide Compiles the numerous contradictory reports about the effects of marijuana and cardiovascular disease for ease in comparison Examines the mechanisms that have shown how marijuana use might contribute to the development of chronic cardiovascular conditions and/or acutely trigger cardiovascular events Includes coverage of the drug's role in pharmacotherapy

The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publsiher: National Academies Press
Total Pages: 486
Release: 2017-05-01
ISBN: 0309453046
Category: Science
Language: EN, FR, DE, ES & NL

The Health Effects of Cannabis and Cannabinoids Book Excerpt:

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Principles of Addiction Medicine

Principles of Addiction Medicine
Author: Richard K. Ries,Shannon C. Miller,David A. Fiellin
Publsiher: Lippincott Williams & Wilkins
Total Pages: 1594
Release: 2009
ISBN: 9780781774772
Category: Psychology
Language: EN, FR, DE, ES & NL

Principles of Addiction Medicine Book Excerpt:

This respected text from the American Society of Addiction Medicine is valuable for all physicians and mental-health personnel who specialize in addiction medicine and who treat patients with addiction disorders. The chapters blend scientific principles underlying addiction with the practical essentials of clinical addiction medicine. Many of the contributors are affiliated with leading government agencies that study addiction and its science, such as the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse. The book will appeal to a wide and interdisciplinary range of professionals, especially those with interest or duties relating to addiction-related disorders, and in particular physicians seeking certification status via either the American Board of Addiction Medicine or the American Board of Psychiatry and Neurology. A companion Website will offer the fully searchable text.

Cannabis and Cannabinoid based Medicines in Cancer Care

Cannabis and Cannabinoid based Medicines in Cancer Care
Author: Claude Cyr,Mellar P. Davis,Danial Schecter,Paul Daeninck
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN: 3030899187
Category: Cancer
Language: EN, FR, DE, ES & NL

Cannabis and Cannabinoid based Medicines in Cancer Care Book Excerpt:

The use of cannabinoid-based medicines (CBM), and cannabis in particular, has risen steadily among cancer and palliative care patients over the last few years. This textbook aims to address the multiple challenges facing healthcare providers regarding the use of CBM in this vulnerable patient population. It provides insight into the latest preclinical and clinical data and offers a practical approach on the use of CBM in a rapidly evolving landscape. It answers questions regarding the prescribing process and elucidates controversies regarding cannabis disease-modifying effects. The first chapters will review basic concepts of the endocannabinoid system and pharmacology of CBM, while focusing more specifically on the unique characteristics of two main cannabinoids: THC and CBD. Indicating which benefits can be expected from using either or both of these compounds, the book then addresses issues of drug-drug interactions and other challenges involved in prescribing CBM to frail patients with polypharmacy and multiple comorbidities. Comparing available products, both approved and non-approved by the FDA, the book discusses regional challenges for accessing reliably tested and labelled products in the context of standardization efforts. After carefully determining objectives and addressing patient expectations, further chapters will examine the different clinical settings in which CBM may be useful in cancer care and explore symptom management, including cancer pain, anxiety, nausea, and insomnia among others. The possible benefits of cannabis psychoactivity will also be discussed, including harm reduction strategies for patients who wish to explore these effects. Cannabis and Cannabinoid-Based Medicines in Cancer Care: A Comprehensive Guide to Medical Management serves as a comprehensive text for oncologists, palliative care specialists, general practitioners, and nurse practitioners working with cancer patients or in palliative care settings.

CBD

CBD
Author: Linda A. Parker,Erin M. Rock,Raphael Mechoulam
Publsiher: MIT Press
Total Pages: 320
Release: 2022-08-02
ISBN: 0262370417
Category: Health & Fitness
Language: EN, FR, DE, ES & NL

CBD Book Excerpt:

A comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies. CBD (cannabidiol), a nonintoxicating compound derived from the cannabis plant, can be found in products ranging from lotion and smoothies to chewable gummies and pet treats. It’s been promoted—but not always scientifically validated—as a treatment for medical conditions including psychosis, anxiety, pain, and even cancer. This book by three leading cannabis researchers looks at the science of CBD. It offers a comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies. The authors report that the current CBD fad has some basis in preclinical animal research that indicates potential beneficial effects. Clinical studies, hampered by regulations governing research with cannabis, have lagged behind the basic animal research. The authors examine what research shows about chemical and pharmacological aspects of CBD and CBD’s interaction with THC, the main psychotropic compound found in cannabis. They go on to review current state of knowledge about CBD’s effectiveness in treating epilepsy, cancer, nausea, pain, anxiety, PTSD, depression, sleep disorders, psychosis, and addiction.

Cannabinoids in Health and Disease

Cannabinoids in Health and Disease
Author: Rosaria Meccariello,Rosanna Chianese
Publsiher: BoD – Books on Demand
Total Pages: 258
Release: 2016-06-15
ISBN: 9535124293
Category: Medical
Language: EN, FR, DE, ES & NL

Cannabinoids in Health and Disease Book Excerpt:

This book provides a comprehensive overview of current knowledge of cannabinoid activity in human physiology and points out the importance of endocannabinoid system for the maintenance of human health and treatment of diseases. Each chapter has been organized with the aim to cover basic concepts in the modulation of endocannabinoid system in both physiological and pathological conditions, thanks to the integration of data from experimental animal models and clinical observations. A special focus has been put on the medical use of cannabinoids and on the targeting of endocannabinoid system as new therapeutic strategy for the prevention and treatment of human diseases. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding in the field of cannabinoids.

Cannabis in Medical Practice

Cannabis in Medical Practice
Author: Mary Lynn Mathre, R.N.
Publsiher: McFarland
Total Pages: 247
Release: 2012-11-12
ISBN: 0786483903
Category: Medical
Language: EN, FR, DE, ES & NL

Cannabis in Medical Practice Book Excerpt:

Because marijuana is a Schedule I drug under the Controlled Substances Act, the therapeutic benefits of cannabis are no longer mentioned in the formal education of health care professionals. Doctors who do learn of the drug’s therapeutic value are often intimidated by its illegal status. Thus millions of patients afflicted with such illnesses as glaucoma, AIDS, cancer, multiple sclerosis, spinal cord injuries, seizure disorders and chronic pain are denied access to information about the drug’s benefits and, in many cases, suffer needlessly. Straightforward and nonpoliticized information on the therapeutic uses of cannabis is provided here by medical, legal and scientific professionals. Legal issues, a worldwide history of therapeutic cannabis and a discussion of its pharmacology are covered. Specific medical uses are then examined, including its application for sufferers of cancer, AIDS, glaucoma, and seizure disorders, and its potential use in psychiatry. Dosages and administration of cannabis are explored, along with considerations on the use of the drug during pregnancy and the risks of addiction and dependency.

Cannabis Extracts in Medicine

Cannabis Extracts in Medicine
Author: Jeffrey Dach, M.D.,,Elaine A. Moore,Justin Kander
Publsiher: McFarland
Total Pages: 220
Release: 2015-10-16
ISBN: 0786496630
Category: Medical
Language: EN, FR, DE, ES & NL

Cannabis Extracts in Medicine Book Excerpt:

“Policy makers in states considering legalizing marijuana for medical purposes should read this well-researched book...recommended“—Choice “For students, academics, researchers, medical professionals and general interest readers...presents an examination of the potential medicinal uses of cannabis extracts.“—Reference & Research Book News As of December 2014, medicinal cannabis is legal in 23 states where news and medical journals report success stories of people recovering from diverse medical conditions such as epilepsy, cancer and chronic pain. In states where cannabis remains illegal, users and providers risk arrest and imprisonment. While the United States government has restricted cannabis medical research, advances have been made in Israel, Spain and Italy. One such breakthrough was the discovery of the endocannabinoid system in the brain and immune system. Endogenous cannabinoids are mimicked by THC and cannabidiol (CBD), cannabinoids found in the cannabis plant, thus accounting for its medicinal effects. Focusing on the biochemical properties, medical benefits and psychological effects of cannabinoids, this book provides an overview of anecdotal case reports, animal studies and clinical trials proposing cannabis for seizure disorder, cancer, chronic pain and other medical conditions.

Handbook of Cannabis

Handbook of Cannabis
Author: Roger Pertwee
Publsiher: OUP Oxford
Total Pages: 632
Release: 2014-08-21
ISBN: 0191639699
Category: Science
Language: EN, FR, DE, ES & NL

Handbook of Cannabis Book Excerpt:

Truly global in scope and with contributions from leading researchers around the world, The Handbook of Cannabis is the definitive resource on this fascinating drug. Combining scientific perspectives and clinical applications, it covers a vast array of topics, from why over the centuries cannabis has been used as a medicine, through the regulations facing those wishing to self-administer cannabis or provide cannabis-based medicines, to the chemical structure of its many constituents and the rapidly growing group of synthetic cannabinoids that are currently being used for 'legal highs'. With each chapter written by a group of one or more internationally recognised subject experts, it provides academics and researchers with authoritative scientific material on the main pharmacological actions and their effects, as well as their pharmacokinetics, metabolism, and forensic detection. In addition it also examines the complex morphology, cultivation, harvesting, and processing of cannabis and the ways in which the plant's chemical composition can be controlled. As well as offering a raft of scientific information there is extensive coverage of cannabinoid-based medicines. Helping readers to identify and evaluate their benefits, chapters explore pharmacological actions and the effects that seem to underlie approved therapeutic uses, how they are currently used to treat certain disorders, and the ever-growing number of wide-ranging potential clinical applications. There is also coverage of both the legal and illegal sources of cannabis, including 'coffee shops' and 'cannabis dispensaries'. The complex issue of 'recreational cannabis' is also tackled. The sought-after and adverse psychological and non-psychological effects are described and discussions are included on how some adverse effects can be lessened by at least one constituent of cannabis, and that it might be possible to reduce the harm that cannabis does to some by changing current regulatory policies. The Handbook of Cannabis is a one-stop reference; essential reading for all clinicians, pharmacologists, psychologists, and psychiatrists interested in this drug, as well as those working in the field of public health.

Cannabinoid Pharmacology

Cannabinoid Pharmacology
Author: Anonim
Publsiher: Academic Press
Total Pages: 492
Release: 2017-08-18
ISBN: 0128112336
Category: Medical
Language: EN, FR, DE, ES & NL

Cannabinoid Pharmacology Book Excerpt:

Cannabinoid Pharmacology, Volume 80 is a new volume in the Advances in Pharmacology that presents reviews of recent breakthroughs. This volume aims to present current knowledge of the endogenous cannabinoid system, and looks at molecular, cellular, tissue and organismal effects of endogenous and exogenous cannabinoids. Topics of note in this new volume include Endocannabinoids and their congeners, Endocannabinoid turnover, Plant cannabinoids, Synthetic cannabinoids and ‘legal highs’, CB1 and CB2 cannabinoid receptors, Novel signaling modalities, Novel cannabinoid receptors, and Ion channel regulation by cannabinoids. There is a broad coverage of the essential elements associated with the cannabinoid system. The Editors have sought to include authors who represent authoritative voices on these themes, but have not previously worked together to allow a fresh approach to the individual aspects covered. Presents reviews of recent breakthroughs in the cannabinoid system Features chapters from the best authors in the field Provides an essential resource for scientists, advanced undergraduate students through to established faculty members

Pharmacological Properties of Plant Derived Natural Products and Implications for Human Health

Pharmacological Properties of Plant Derived Natural Products and Implications for Human Health
Author: George E. Barreto,Amirhossein Sahebkar
Publsiher: Springer Nature
Total Pages: 603
Release: 2021-04-16
ISBN: 3030648729
Category: Medical
Language: EN, FR, DE, ES & NL

Pharmacological Properties of Plant Derived Natural Products and Implications for Human Health Book Excerpt:

Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.

Addiction in the Older Patient

Addiction in the Older Patient
Author: Associate Professor of Clinical Psychiatry Maria Sullivan,Frances Levin,Kennedy-Leavy Professor of Clinical Psychiatry Frances Levin
Publsiher: Oxford University Press
Total Pages: 320
Release: 2016-08-30
ISBN: 0199392064
Category: Electronic Book
Language: EN, FR, DE, ES & NL

Addiction in the Older Patient Book Excerpt:

This text focuses on the under-recognized and undertreated problem of addiction in later life. The widespread lack of clinical knowledge about this patient population can be traced to several sources: the systematic exclusion of older individuals from clinical trials; their reluctance to seek medical help owing to stigma and shame; the fact that additive disorders may be disguised by concurrent medical conditions; a lack of screening instruments tailored to an older population; and the low sensitivity of standard diagnostic criteria for detecting addiction in middle-aged and elderly adults who do not display the occupational and legal "red flags" seen in younger individuals. This volume provides the reader with a clear sense of the surprisingly high prevalence of alcohol and substance use disorders in older adults. For each of the major classes of addictive substances, both prescribed and illicit, this book highlights the key clinical issues that can complicate successful diagnosis. The authors describe strategies for initial engagement with the patient, including screening instruments, brief interventions which can be adapted to a primary care setting, emerging web-based and mobile technologies, and treatment strategies which are tailored to the age-appropriate needs of older adults, including older women - who have been found to be especially vulnerable to prescription drug misuse. With the aging of the baby boomers, a generation arriving in middle-age with greater exposure to alcohol and drugs than any previous cohort, the need for successful identification and effective treatment of alcohol and substance use disorders in later life has become a clinical imperative. Addiction in the Older Patient, whose editors bring more than 40 years of combined research and clinical experience in the field of addiction treatment, offers a comprehensive introduction to this underexplored and timely topic. This text synthesizes current clinical evidence to support the most effective strategies for discovering and treating addictive disorders in our older patients.

A Psychiatrist s View of Marijuana

A Psychiatrist s View of Marijuana
Author: Timmen Cermak
Publsiher: Cambridge University Press
Total Pages: 150
Release: 2020-02-29
ISBN: 1108735738
Category: Medical
Language: EN, FR, DE, ES & NL

A Psychiatrist s View of Marijuana Book Excerpt:

An essential guide covering the scientific knowledge and communication skills required to deliver objective patient advice about marijuana use.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog
Author: National Library of Medicine (U.S.)
Publsiher: Unknown
Total Pages: 135
Release: 2022
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

National Library of Medicine Current Catalog Book Excerpt:

Biological Research on Addiction

Biological Research on Addiction
Author: Anonim
Publsiher: Academic Press
Total Pages: 758
Release: 2013-05-17
ISBN: 0123983606
Category: Psychology
Language: EN, FR, DE, ES & NL

Biological Research on Addiction Book Excerpt:

Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual’s susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. Each article provides glossary, full references, suggested readings, and a list of web resources Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available Discusses the genetic basis of addiction Covers basic science research from a variety of animal studies

New Trends of Substance Abuse Looking for New Psychotropic Effects of Chem Sex Drugs Cognitive Enhancers and New Psychoactive Substances

New Trends of Substance Abuse  Looking for New Psychotropic Effects of Chem Sex Drugs  Cognitive Enhancers  and New Psychoactive Substances
Author: Simona Zaami,Simona Pichini,Marta Torrens,Norbert Leo Scherbaum
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-01-08
ISBN: 2889663663
Category: Medical
Language: EN, FR, DE, ES & NL

New Trends of Substance Abuse Looking for New Psychotropic Effects of Chem Sex Drugs Cognitive Enhancers and New Psychoactive Substances Book Excerpt:

Research Grants Index

Research Grants Index
Author: National Institutes of Health (U.S.). Division of Research Grants
Publsiher: Unknown
Total Pages: 1124
Release: 1973
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Research Grants Index Book Excerpt:

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1980
ISBN: 1928374650XXX
Category: Medicine
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Excerpt:

Natural Phenolic Compounds for Health Food and Cosmetic Applications

Natural Phenolic Compounds for Health  Food and Cosmetic Applications
Author: Lucia Panzella
Publsiher: MDPI
Total Pages: 230
Release: 2021-01-20
ISBN: 303936734X
Category: Medical
Language: EN, FR, DE, ES & NL

Natural Phenolic Compounds for Health Food and Cosmetic Applications Book Excerpt:

Based on their potent antioxidant properties, the possible exploitation of natural phenolic compounds as food supplements as well as functional ingredients in the food and cosmetic industry is gaining more and more attention. This book contains original research articles and a review reporting innovative applications of natural phenolic compounds in the field of nutrition and biomedicine, as active ingredients for the prevention of oxidative-stress-related diseases, and as additives in smart food packaging, biomedical devices, and cosmetic products. The growing importance of agri-food wastes as easily accessible sources of phenolic compounds as well as of synthetic derivatives of natural compounds with improved antioxidant properties is also highlighted. Finally, novel technologies to improve extraction yields, stability, bioavailability, and delivery of antioxidant compounds for healthcare products or for skin applications are described.

Your Cannabis CBD THC Ratio

Your Cannabis CBD THC Ratio
Author: Uwe Blesching
Publsiher: Ed Rosenthal
Total Pages: 240
Release: 2020-12-15
ISBN: 193680753X
Category: Medical
Language: EN, FR, DE, ES & NL

Your Cannabis CBD THC Ratio Book Excerpt:

The author of the game-changing Cannabis Health Index returns with a book designed specifically for general readers who want to understand how THC and CBD can benefit them. While CBD is the new buzzword for health and wellness, many researchers and practitioners believe that the symbiotic relationship between THC and CBD, known as the entourage effect, allows for greater therapeutic benefits for patients. Unfortunately, when it comes to optimizing that ratio to a particular health condition, it is often a process of trial and error for medical patients. Your Cannabis CBD:THC Ratio provides detailed information on how to find the best ratios of CBD:THC and covers the preferred ratios of these two primary cannabinoids for ten prevalent medical conditions —including cancer, chronic pain, anxiety, insomnia, and many others. Blesching’s unique chemotype-based system takes into account CBD:THC ratios, the various forms of cannabis medicine available to consumers, and the subjective therapeutic dosages, presenting a complete evidence-based methodology. -- Uwe Blesching, PH.D.