Description : A complete full-colour version of the best selling Understanding Biology for Advanced Level Student Book. This revised edition includes popular topics such as Biotechnology and Human Disease.
Description : The complexity of living organisms surpasses our unaided habilities of analysis. Hence, computational and mathematical methods are necessary for increasing our understanding of biological systems. At the same time, there has been a phenomenal recent progress allowing the application of novel formal methods to new domains. This progress has spurred a conspicuous optimism in computational biology. This optimism, in turn, has promoted a rapid increase in collaboration between specialists of biology with specialists of computer science. Through sheer complexity, however, many important biological problems are at present intractable, and it is not clear whether we will ever be able to solve such problems. We are in the process of learning what kind of model and what kind of analysis and synthesis techniques to use for a particular problem. Some existing formalisms have been readily used in biological problems, others have been adapted to biological needs, and still others have been especially developed for biological systems. This Research Topic has examples of cases (1) employing existing methods, (2) adapting methods to biology, and (3) developing new methods. We can also see discrete and Boolean models, and the use of both simulators and model checkers. Synthesis is exemplified by manual and by machine-learning methods. We hope that the articles collected in this Research Topic will stimulate new research.
Description : A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineering. Written by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research.
Description : International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional scientists
Description : Introduces readers to the enlightening world of the modern light microscope There have been rapid advances in science and technology over the last decade, and the light microscope, together with the information that it gives about the image, has changed too. Yet the fundamental principles of setting up and using a microscope rests upon unchanging physical principles that have been understood for years. This informative, practical, full-colour guide fills the gap between specialised edited texts on detailed research topics, and introductory books, which concentrate on an optical approach to the light microscope. It also provides comprehensive coverage of confocal microscopy, which has revolutionised light microscopy over the last few decades. Written to help the reader understand, set up, and use the often very expensive and complex modern research light microscope properly, Understanding Light Microscopy keeps mathematical formulae to a minimum—containing and explaining them within boxes in the text. Chapters provide in-depth coverage of basic microscope optics and design; ergonomics; illumination; diffraction and image formation; reflected-light, polarised-light, and fluorescence microscopy; deconvolution; TIRF microscopy; FRAP & FRET; super-resolution techniques; biological and materials specimen preparation; and more. Gives a didactic introduction to the light microscope Encourages readers to use advanced fluorescence and confocal microscopes within a research institute or core microscopy facility Features full-colour illustrations and workable practical protocols Understanding Light Microscopy is intended for any scientist who wishes to understand and use a modern light microscope. It is also ideal as supporting material for a formal taught course, or for individual students to learn the key aspects of light microscopy through their own study.
Description : Essentials of Molecular Biology, Fourth Edition focuses on the fundamental aspects of molecular structure and function by reviewing key features and along the way, capsulizing them as a series of concise concepts. Thus, students are encouraged to place the reductionist knowledge of molecular biology into broad contexts and thereby develop both academic and personal meaning for this discipline.
Description : Looks at the complex interrelationships between human culture and the nature. Covering the period from the beginning of agriculture right up to the present day, it focuses on issues relating to human health and well-being and the state of our natural environment. From his vast survey, author Stephen Boyden draws some key conclusions critical to the future of humanity.
Description : What is the relationship between criminality and biology? Nineteenth-century phrenologists insisted that criminality was innate, a trait inherent in the offender’s brain matter. While they were eventually repudiated as pseudo-scientists and self-deluded charlatans, today the pendulum has swung back. Both criminologists and biologists have begun to speak of a tantalizing but disturbing possibility: that criminality may be inherited as a set of genetic deficits that place one at risk for theft, violence, and sexual deviance. If that is so, we may soon confront proposals for genetically modifying “at risk” fetuses or doctoring up criminals so their brains operate like those of law-abiding citizens. In The Criminal Brain, well-known criminologist Nicole Rafter traces the sometimes violent history of these criminological theories and provides an introduction to current biological theories of crime, or biocriminology, with predictions of how these theories are likely to develop in the future. What do these new theories assert? Are they as dangerous as their forerunners, which the Nazis and other eugenicists used to sterilize, incarcerate, and even execute thousands of supposed “born” criminals? How can we prepare for a future in which leaders may propose crime-control programs based on biology? Enhanced with fascinating illustrations and written in lively prose, The Criminal Brain examines these issues in light of the history of ideas about the criminal brain. By tracing the birth and growth of enduring ideas in criminology, as well as by recognizing historical patterns in the interplay of politics and science, she offers ways to evaluate new theories of the criminal brain that may radically reshape ideas about the causes of criminal behavior.
Description : The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.
Description : A study traces violent behavior to changes in the chemistry of the brain that occur over a lifetime in response to particular environments